Jakob Linseisen

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. pmc The impact of education on risk factors and the occurrence of multimorbidity in the EPIC-Heidelberg cohort
    Gabriele Nagel
    Institute of Epidemiology, Ulm University, Ulm, Germany
    BMC Public Health 8:384. 2008
  2. doi request reprint Biomarkers of dietary intake of flavonoids and phenolic acids for studying diet-cancer relationship in humans
    Jakob Linseisen
    Unit of Nutritional Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
    Eur J Nutr 47:60-8. 2008
  3. doi request reprint Serum undercarboxylated osteocalcin as biomarker of vitamin K intake and risk of prostate cancer: a nested case-control study in the Heidelberg cohort of the European prospective investigation into cancer and nutrition
    Katharina Nimptsch
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg DE 69120, Germany
    Cancer Epidemiol Biomarkers Prev 18:49-56. 2009
  4. pmc Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk
    Sascha Abbas
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany
    Breast Cancer Res 10:R31. 2008
  5. doi request reprint The association between dietary vitamin K intake and serum undercarboxylated osteocalcin is modulated by vitamin K epoxide reductase genotype
    Katharina Nimptsch
    Unit of Nutritional Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg DE 69120, Germany
    Br J Nutr 101:1812-20. 2009
  6. doi request reprint The Gc2 allele of the vitamin D binding protein is associated with a decreased postmenopausal breast cancer risk, independent of the vitamin D status
    Sascha Abbas
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 17:1339-43. 2008
  7. doi request reprint Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk
    Birgit Hoeft
    German Cancer Research Center, Heidelberg, Germany
    Carcinogenesis 31:466-72. 2010
  8. doi request reprint Level of education and the risk of lymphoma in the European prospective investigation into cancer and nutrition
    Silke Hermann
    Division of Cancer Epidemiology C020, German Cancer Research Center, Heidelberg, Germany
    J Cancer Res Clin Oncol 136:71-7. 2010
  9. doi request reprint Dietary vitamin K intake in relation to cancer incidence and mortality: results from the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg)
    Katharina Nimptsch
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Am J Clin Nutr 91:1348-58. 2010
  10. doi request reprint Consistency of vitamin and/or mineral supplement use and demographic, lifestyle and health-status predictors: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg cohort
    Kuanrong Li
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Br J Nutr 104:1058-64. 2010

Detail Information

Publications103 found, 100 shown here

  1. pmc The impact of education on risk factors and the occurrence of multimorbidity in the EPIC-Heidelberg cohort
    Gabriele Nagel
    Institute of Epidemiology, Ulm University, Ulm, Germany
    BMC Public Health 8:384. 2008
    ..Thus, we investigated the association between educational attainment and multimorbidity in a prospective cohort study, taking also into account intermediate factors that could explain such associations...
  2. doi request reprint Biomarkers of dietary intake of flavonoids and phenolic acids for studying diet-cancer relationship in humans
    Jakob Linseisen
    Unit of Nutritional Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
    Eur J Nutr 47:60-8. 2008
    ..Since dietary intake estimates suffer from imprecision, the measurement of these compounds (or metabolites of) in biological specimens collected in epidemiological studies is expected to improve accuracy of exposure estimation...
  3. doi request reprint Serum undercarboxylated osteocalcin as biomarker of vitamin K intake and risk of prostate cancer: a nested case-control study in the Heidelberg cohort of the European prospective investigation into cancer and nutrition
    Katharina Nimptsch
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg DE 69120, Germany
    Cancer Epidemiol Biomarkers Prev 18:49-56. 2009
    ..37). The increased risks of advanced-stage and high-grade prostate cancer with higher serum ucOC/iOC ratio strengthen the findings for dietary menaquinone intake...
  4. pmc Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk
    Sascha Abbas
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany
    Breast Cancer Res 10:R31. 2008
    ..Effect modification by serum 25-hydroxyvitamin D (25 [OH]D), the biomarker for vitamin D status in humans, has rarely been examined...
  5. doi request reprint The association between dietary vitamin K intake and serum undercarboxylated osteocalcin is modulated by vitamin K epoxide reductase genotype
    Katharina Nimptsch
    Unit of Nutritional Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg DE 69120, Germany
    Br J Nutr 101:1812-20. 2009
    ..Thus, the results show that the inverse association between dietary vitamin K intake and serum ucOC depends on a functionally relevant allelic variant of the VKORC1 gene...
  6. doi request reprint The Gc2 allele of the vitamin D binding protein is associated with a decreased postmenopausal breast cancer risk, independent of the vitamin D status
    Sascha Abbas
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 17:1339-43. 2008
    ..Our results provide evidence for a serum 25(OH)D-independent effect of Gc2 allele carrier status in postmenopausal breast cancer...
  7. doi request reprint Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk
    Birgit Hoeft
    German Cancer Research Center, Heidelberg, Germany
    Carcinogenesis 31:466-72. 2010
    ..Our results support the key role of prostanoid signaling in colon carcinogenesis and suggest a relevance of genetic variation in fatty acid metabolism-related genes and CRC risk...
  8. doi request reprint Level of education and the risk of lymphoma in the European prospective investigation into cancer and nutrition
    Silke Hermann
    Division of Cancer Epidemiology C020, German Cancer Research Center, Heidelberg, Germany
    J Cancer Res Clin Oncol 136:71-7. 2010
    ..We explored the association between education and the incidence of lymphoma in the prospective EPIC study...
  9. doi request reprint Dietary vitamin K intake in relation to cancer incidence and mortality: results from the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg)
    Katharina Nimptsch
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Am J Clin Nutr 91:1348-58. 2010
    ..Anticarcinogenic activities of vitamin K have been observed in animal and cell studies...
  10. doi request reprint Consistency of vitamin and/or mineral supplement use and demographic, lifestyle and health-status predictors: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg cohort
    Kuanrong Li
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Br J Nutr 104:1058-64. 2010
    ..We concluded that supplement use is a fairly unstable behaviour in free-living individuals. Individuals with a favourable lifestyle and healthier diet are more likely to show consistent supplementation...
  11. doi request reprint Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and herceptin 2 receptor status
    Aida Karina Zaineddin
    Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Int J Cancer 130:1401-10. 2012
    ..The overall evidence together with other studies supports an inverse association between higher serum enterolactone levels and postmenopausal breast cancer risk...
  12. doi request reprint Dietary intake of individual glucosinolates in participants of the EPIC-Heidelberg cohort study
    Astrid Steinbrecher
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Ann Nutr Metab 54:87-96. 2009
    ..To compile a database on content of individual glucosinolates in food and to describe the dietary intake of individual glucosinolates in a German population...
  13. doi request reprint Consumption of meat and dairy and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition
    Sabine Rohrmann
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Int J Cancer 128:623-34. 2011
    ..Chance is a plausible explanation of the observed associations, which need to be confirmed in further studies...
  14. doi request reprint Heterocyclic aromatic amine intake increases colorectal adenoma risk: findings from a prospective European cohort study
    Sabine Rohrmann
    Unit of Nutritional Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Am J Clin Nutr 89:1418-24. 2009
    ..Heterocyclic aromatic amines (HCAs), which arise from cooking meat and fish at high temperatures, may increase the risk of colorectal adenomas. Conversely, flavonoids might counteract the negative effects of HCAs...
  15. doi request reprint Vitamin/mineral supplementation and cancer, cardiovascular, and all-cause mortality in a German prospective cohort (EPIC-Heidelberg)
    Kuanrong Li
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Eur J Nutr 51:407-13. 2012
    ..To prospectively evaluate the association of vitamin/mineral supplementation with cancer, cardiovascular, and all-cause mortality...
  16. doi request reprint Dietary glucosinolate intake, polymorphisms in selected biotransformation enzymes, and risk of prostate cancer
    Astrid Steinbrecher
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 19:135-43. 2010
    ..This information will help to further elucidate the mechanism of action of potentially protective substances in vivo...
  17. ncbi request reprint Fruit and vegetable consumption and lung cancer risk: updated information from the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Jakob Linseisen
    Division of Clinical Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Int J Cancer 121:1103-14. 2007
    ..In addition to an overall inverse association with fruit intake, the results of this evaluation add evidence for a significant inverse association of vegetable consumption and lung cancer incidence in smokers...
  18. doi request reprint The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study
    Aida Karina Zaineddin
    Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Nutr Cancer 64:652-65. 2012
    ..Our results provide evidence for a reduced postmenopausal breast cancer risk associated with increased consumption of sunflower and pumpkin seeds and soybeans...
  19. doi request reprint Serum enterolactone and prognosis of postmenopausal breast cancer
    Katharina Buck
    Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    J Clin Oncol 29:3730-8. 2011
    ..Dietary lignans are metabolized to enterolignans, which are subsequently absorbed and become bioavailable...
  20. ncbi request reprint Dietary intake of vitamin K and risk of prostate cancer in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg)
    Katharina Nimptsch
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Am J Clin Nutr 87:985-92. 2008
    ..Epidemiologic studies linking dietary intake of vitamin K with the development of prostate cancer have not yet been conducted...
  21. doi request reprint Alcohol consumption and the risk for prostate cancer in the European Prospective Investigation into Cancer and Nutrition
    Sabine Rohrmann
    Division of Cancer Epidemiology C020, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 17:1282-7. 2008
    ..No statistically significant association was observed for alcohol intake from specific alcoholic beverages. Our results indicate no association between the consumption of alcohol and prostate cancer in this cohort of European men...
  22. doi request reprint Concentrations of IGF-I and IGFBP-3 and brain tumor risk in the European Prospective Investigation into Cancer and Nutrition
    Sabine Rohrmann
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 20:2174-82. 2011
    ..Insulin-like growth factor-1 (IGF-I) is important in normal brain development but in the adult brain, IGF-I overexpression may be a risk factor for tumor development...
  23. doi request reprint Association of hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) variants and colorectal cancer risk
    Bernd Frank
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Carcinogenesis 32:190-6. 2011
    ..82, 95% CI = 0.70, 0.95, P = 0.01) as well as among smokers (OR = 0.74, 95% CI = 0.61, 0.90, P = 0.003). Yet, our data do not support the previously reported associations of HPGD tagSNPs and risk of CRC...
  24. doi request reprint Plasma 25-hydroxyvitamin D and premenopausal breast cancer risk in a German case-control study
    Sascha Abbas
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Int J Cancer 124:250-5. 2009
    ..05, case-only model). Our findings support a protective effect of vitamin D for premenopausal breast cancer...
  25. ncbi request reprint Fruit and vegetable consumption and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Sabine Rohrmann
    Division of Clinical Epidemiology C020, German Cancer Research Centre, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany
    Cancer Causes Control 18:537-49. 2007
    ..The best-established risk factors are related to dys-regulation of immune function, and evidence suggests that factors such as dietary or lifestyle habits may be involved in the etiology...
  26. doi request reprint Smoking and lymphoma risk in the European prospective investigation into cancer and nutrition
    Alexandra Nieters
    Division of Cancer Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Am J Epidemiol 167:1081-9. 2008
    ..Future analysis should involve viral biomarkers and genetic susceptibility markers to elucidate potential mechanisms of smoking-induced carcinogenesis, particularly for Hodgkin's lymphoma...
  27. doi request reprint Lifestyle factors, obesity and the risk of colorectal adenomas in EPIC-Heidelberg
    Silke Hermann
    Division of Cancer Epidemiology C020, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
    Cancer Causes Control 20:1397-408. 2009
    ..We investigated the association of lifestyle and obesity with colorectal adenoma risk in a prospective setting...
  28. doi request reprint Dietary calcium and magnesium intake in relation to cancer incidence and mortality in a German prospective cohort (EPIC-Heidelberg)
    Kuanrong Li
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Cancer Causes Control 22:1375-82. 2011
    ..This prospective cohort study provides no strong evidence to support that high dietary calcium and magnesium intake in the intake range observed in a German population may reduce cancer incidence or mortality...
  29. ncbi request reprint Intake of heterocyclic aromatic amines from meat in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg cohort
    Sabine Rohrmann
    Division of Clinical Epidemiology, German Cancer Research Centre, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Br J Nutr 98:1112-5. 2007
    ..The present study offers the opportunity of a detailed examination of the associations between meat cooking as well as HCA intake from meat and cancer risk in a prospective way...
  30. doi request reprint Intake of heterocyclic aromatic amines and the risk of prostate cancer in the EPIC-Heidelberg cohort
    Anja Sander
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Cancer Causes Control 22:109-14. 2011
    ..Heterocyclic amines (HCA) are positively associated with prostate cancer risk in animal models. Because of mostly inconsistent results of epidemiological studies, we examined the association between intake of HCA and prostate cancer risk...
  31. ncbi request reprint Ethanol intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Sabine Rohrmann
    Division of Clinical Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Am J Epidemiol 164:1103-14. 2006
    ..Although there was no overall association between ethanol intake and risk of lung cancer, the authors cannot rule out a lower risk for moderate consumption and a possibly increased risk for high lifelong consumption...
  32. doi request reprint Associations of dietary calcium intake and calcium supplementation with myocardial infarction and stroke risk and overall cardiovascular mortality in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition study (EPIC-Hei
    Kuanrong Li
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Heart 98:920-5. 2012
    ..However, findings of an ultimately decreased risk of cardiovascular disease (CVD) are limited. Instead, recent evidence warns that taking calcium supplements might increase myocardial infarction (MI) risk...
  33. doi request reprint Lipid peroxidation and DNA adduct formation in lymphocytes of premenopausal women: Role of estrogen metabolites and fatty acid intake
    Xin Sun
    Division of Toxicology and Cancer Risk Factors, German Cancer Research Center, DKFZ, Heidelberg 69120, Germany
    Int J Cancer 131:1983-90. 2012
    ..Similar studies in human breast epithelial tissue and on amplification of DNA-damage in breast cancer patients are in progress...
  34. doi request reprint Effects of selenium status and polymorphisms in selenoprotein genes on prostate cancer risk in a prospective study of European men
    Astrid Steinbrecher
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 19:2958-68. 2010
    ..We evaluated the association between serum selenium status and prostate cancer risk in a population with relative low selenium concentrations considering effect modification by genetic variants in selenoprotein genes...
  35. doi request reprint Meta-analyses of lignans and enterolignans in relation to breast cancer risk
    Katharina Buck
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Am J Clin Nutr 92:141-53. 2010
    ..Epidemiologic studies that examined whether lignans, the most important class of phytoestrogens in the Western diet, protect against breast cancer have yielded inconsistent results...
  36. doi request reprint Socio-demographic characteristics of participation in the opportunistic German cervical cancer screening programme: results from the EPIC-Heidelberg cohort
    David Seidel
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
    J Cancer Res Clin Oncol 135:533-41. 2009
    ..To analyse participation in the German cervical cancer screening programme by socio-demographic characteristics...
  37. ncbi request reprint Lifestyle and diet in people using dietary supplements: a German cohort study
    Annika Reinert
    Division of Cancer Epidemiology, German Cancer Research Centre, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Eur J Nutr 46:165-73. 2007
    ..The use of dietary supplements is often associated with a healthy lifestyle. Due to high variation in supplementation practice by country, these associations will be investigated in a large German cohort study...
  38. ncbi request reprint Plasma 7beta-hydroxycholesterol as a possible predictor of lung cancer risk
    Jakob Linseisen
    German Cancer Research Centre, Division of Clinical Epidemiology, Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 11:1630-7. 2002
    ..Because of the rather high-risk estimate, research on possible intrinsic biological effects of this compound should be encouraged...
  39. doi request reprint Plasma 25-hydroxyvitamin D and the risk of breast cancer in the European prospective investigation into cancer and nutrition: a nested case-control study
    Tilman Kühn
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, Heidelberg, Germany
    Int J Cancer 133:1689-700. 2013
    ..This result is in line with findings in the majority of prospective studies and does not support a role of vitamin D in the development of breast cancer. ..
  40. doi request reprint Polymorphisms of genes coding for ghrelin and its receptor in relation to anthropometry, circulating levels of IGF-I and IGFBP-3, and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (
    Laure Dossus
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany
    Carcinogenesis 29:1360-6. 2008
    ..These associations, however, might also be due to chance findings and further large studies are needed to confirm our results...
  41. doi request reprint Effect of dietary fatty acid intake on prospective weight change in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition
    Katharina Nimptsch
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, Germany
    Public Health Nutr 13:1636-46. 2010
    ....
  42. pmc Ethanol intake and the risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Sabine Rohrmann
    Division of Clinical Epidemiology, German Cancer Research Centre, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Cancer Causes Control 20:785-94. 2009
    ..To examine the association of baseline and lifetime ethanol intake with cancer of the pancreas in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  43. ncbi request reprint Long-term reproducibility of a food-frequency questionnaire and dietary changes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heidelberg cohort
    Gabriele Nagel
    Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Br J Nutr 98:194-200. 2007
    ..For some nutrients the dietary changes were consistent with results from independent national surveys. The performance of the FFQ gives confidence in the dietary data to be used as long-term exposure variables...
  44. ncbi request reprint Socioeconomic position and the risk of gastric and oesophageal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    Gabriele Nagel
    Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Int J Epidemiol 36:66-76. 2007
    ..To evaluate the association of socioeconomic position with adenocarcinoma of the oesophagus and stomach...
  45. doi request reprint Dietary intake of vitamin D and calcium and breast cancer risk in the European Prospective Investigation into Cancer and Nutrition
    Sascha Abbas
    German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg, Germany
    Nutr Cancer 65:178-87. 2013
    ..57 and 0.22 in pre- and postmenopausal women, respectively). In this large prospective cohort, we found no evidence for an association between dietary vitamin D or calcium intake and breast cancer risk...
  46. doi request reprint Meat and fish consumption and risk of pancreatic cancer: results from the European Prospective Investigation into Cancer and Nutrition
    Sabine Rohrmann
    Division of Cancer Epidemiology and Prevention, Institute of Social and Preventive Medicine, University of Zurich, Zurich, Switzerland
    Int J Cancer 132:617-24. 2013
    ..The positive association of poultry consumption with pancreatic cancer might be a chance finding as it contradicts most previous findings...
  47. doi request reprint Dietary glucosinolate intake and risk of prostate cancer in the EPIC-Heidelberg cohort study
    Astrid Steinbrecher
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Int J Cancer 125:2179-86. 2009
    ..This study shows an inverse association between dietary intake of GLS and the risk of prostate cancer. Because this is the first prospective study using individual GLS intake data, confirmation in other studies is warranted...
  48. doi request reprint Dietary intake of meat and meat-derived heterocyclic aromatic amines and their correlation with DNA adducts in female breast tissue
    Sabine Rohrmann
    Division of Clinical Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Mutagenesis 24:127-32. 2009
    ..Since the detected DNA adducts were not necessarily specific only for HCA, it is possible that HCA intake is a surrogate of other genotoxic substances, such as polycyclic aromatic hydrocarbons, in meat prepared at high temperatures...
  49. ncbi request reprint Serum 25-hydroxyvitamin D and risk of post-menopausal breast cancer--results of a large case-control study
    Sascha Abbas
    Division of Cancer Epidemiology, German Cancer Research Center, 69120 Heidelberg, Germany
    Carcinogenesis 29:93-9. 2008
    ....
  50. pmc The association of education with body mass index and waist circumference in the EPIC-PANACEA study
    Silke Hermann
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    BMC Public Health 11:169. 2011
    ..To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  51. ncbi request reprint Physical activity and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition Cohort
    Karen Steindorf
    Unit of Environmental Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Int J Cancer 119:2389-97. 2006
    ..It can be assumed that the elevated risks found for occupational physical activity are not produced mechanistically by physical activity itself but rather reflect exposure to occupation-related lung cancer risk factors...
  52. ncbi request reprint Dietary vitamin D and calcium intake and premenopausal breast cancer risk in a German case-control study
    Sascha Abbas
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Nutr Cancer 59:54-61. 2007
    ..29). No statistically significant interaction between the 2 nutrients was observed. Our data support a protective effect of dietary vitamin D on premenopausal breast cancer risk independent of dietary calcium intake...
  53. doi request reprint A distinct ERCC1 haplotype is associated with mRNA expression levels in prostate cancer patients
    Andreas Woelfelschneider
    Division of Toxicology and Cancer Risk Factors, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Carcinogenesis 29:1758-64. 2008
    ..Our study further revealed a modulating effect by nutritional factors...
  54. ncbi request reprint Nutrition and breast cancer risk by age 50: a population-based case-control study in Germany
    Silke Hermann
    Department of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Nutr Cancer 44:23-34. 2002
    ....
  55. ncbi request reprint Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort
    Alexandra Nieters
    German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Eur J Nutr 41:210-21. 2002
    ....
  56. ncbi request reprint Reproductive and dietary determinants of the age at menopause in EPIC-Heidelberg
    Gabriele Nagel
    Division of Clinical Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Maturitas 52:337-47. 2005
    ..The aim of the study was to explore the influence of reproductive and dietary factors on the age at menopause...
  57. ncbi request reprint Determinants and correlates of serum undercarboxylated osteocalcin
    Katharina Nimptsch
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Ann Nutr Metab 51:563-70. 2007
    ..To assess dietary and nondietary determinants of serum undercarboxylated osteocalcin (ucOC) as a measure of vitamin K status...
  58. ncbi request reprint Use of hormone replacement therapy (HRT) among women aged 45-64 years in the German EPIC-cohorts
    Gabriele Nagel
    Division of Clinical Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    Maturitas 56:436-46. 2007
    ..To describe the prevalence and to assess type and indicators of hormone replacement therapy (HRT) use in the two German EPIC-cohorts...
  59. ncbi request reprint Dietary intake of different types and characteristics of processed meat which might be associated with cancer risk--results from the 24-hour diet recalls in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Jakob Linseisen
    German Cancer Research Centre, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Public Health Nutr 9:449-64. 2006
    ....
  60. ncbi request reprint Plasma enterolactone and genistein and the risk of premenopausal breast cancer
    Regina Piller
    Unit of Human Nutrition and Cancer Prevention, Technical University of Munich, and German Cancer Research Center, Department of Clinical Epidemiology, Heidelberg, Germany
    Eur J Cancer Prev 15:225-32. 2006
    ..We previously reported an inverse association between dietary phytoestrogen intake and premenopausal breast cancer risk and now examine the relationship with plasma phytoestrogen concentrations...
  61. ncbi request reprint Quantity and quality of dietary fat, carbohydrate, and fiber intake in the German EPIC cohorts
    Jakob Linseisen
    Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Ann Nutr Metab 47:37-46. 2003
    ..This evaluation aims to describe the quantity and quality of dietary fat, carbohydrate and fiber intake in both German cohorts participating in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  62. ncbi request reprint Plasma levels of six carotenoids in nine European countries: report from the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Wael K Al-Delaimy
    Unit of Nutrition and Cancer, International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Public Health Nutr 7:713-22. 2004
    ..Few studies have compared levels of these carotenoids between countries in Europe...
  63. ncbi request reprint Serum C-peptide levels and breast cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Martijn Verheus
    International Agency for Research on Cancer IARC WHO, Lyon, France
    Int J Cancer 119:659-67. 2006
    ..Nevertheless, among older, postmenopausal women, hyperinsulinemia might contribute to increasing breast cancer risk...
  64. ncbi request reprint Association of fatty acids in serum phospholipids with hay fever, specific and total immunoglobulin E
    Iris Kompauer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Br J Nutr 93:529-35. 2005
    ..The present result on the association between hay fever and arachidonic acid is consistent with current hypotheses but warrants further research...
  65. ncbi request reprint Consumption of vegetables and fruits and risk of breast cancer
    Carla H van Gils
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    JAMA 293:183-93. 2005
    ..Most of the evidence comes from case-control studies, but a recent pooled analysis of the relatively few published cohort studies suggests no significantly reduced breast cancer risk is associated with vegetable and fruit consumption...
  66. pmc IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3)
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, United States of America
    PLoS ONE 3:e2578. 2008
    ..In summary, the impact of genetic variation in IGF1 and IGFBP3 on circulating IGF levels does not appear to substantially influence breast cancer risk substantially among primarily Caucasian postmenopausal women...
  67. ncbi request reprint Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study
    Paula Jakszyn
    Department of Epidemiology, Catalan Institute of Oncology, ICO IDIBELL Barcelona, Spain
    Carcinogenesis 27:1497-501. 2006
    ..09). Moreover, we observed an interaction between plasma vitamin C and ENOC (P < 0.02). ENOC formation may account for our previously reported association between red and processed meat consumption and gastric cancer risk...
  68. ncbi request reprint Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC)
    Carlos A Gonzalez
    Department of Epidemiology, Catalan Institute of Oncology, Barcelona, Spain
    J Natl Cancer Inst 98:345-54. 2006
    ..We examined the risks of gastric cancer and esophageal adenocarcinoma associated with meat consumption within the European Prospective Investigation Into Cancer and Nutrition (EPIC) cohort...
  69. ncbi request reprint Fish consumption and breast cancer risk. The European Prospective Investigation into Cancer and Nutrition (EPIC)
    Dagrun Engeset
    Institute of Community Medicine, University of Tromsø, Tromsø, Norway
    Int J Cancer 119:175-82. 2006
    ..Although the period of follow-up is relatively short, the results provide no evidence for an association between fish intake and breast cancer risk...
  70. ncbi request reprint Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    Carlos A Gonzalez
    Department of Epidemiology, Catalan Institute of Oncology, Barcelona ICO IDIBELL, Spain
    Int J Cancer 118:2559-66. 2006
    ..Our study supports a possible protective role of vegetable intake in the intestinal type of GC and the ACO. Citrus fruit consumption may have a role in the protection against cardia GC and ACO...
  71. ncbi request reprint Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Germany
    Int J Cancer 118:728-38. 2006
    ..Our data give further credence to public health efforts aiming to reduce the prevalence of obesity to prevent RCC, in addition to other chronic diseases...
  72. pmc Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition
    Teresa Norat
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69 372 Lyon cedex 08, France
    J Natl Cancer Inst 97:906-16. 2005
    ..Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish intake may be associated with a decreased risk, but the existing evidence is less convincing...
  73. ncbi request reprint 4-Aminobiphenyl-hemoglobin adducts and risk of smoking-related disease in never smokers and former smokers in the European Prospective Investigation into Cancer and Nutrition prospective study
    Luisa Airoldi
    Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Cancer Epidemiol Biomarkers Prev 14:2118-24. 2005
    ..The most important finding of this prospective study is that, at least in women, 4-ABP-Hb adducts may help identify subjects at high risk of cancers related to environmental tobacco smoke exposure...
  74. ncbi request reprint Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nu
    Federico Canzian
    Hormones and Cancer Team, International Agency for Research on Cancer, 150 cours Albert Thomas, F 69372 Lyon, France
    Cancer Epidemiol Biomarkers Prev 14:2316-25. 2005
    ....
  75. ncbi request reprint Anthropometry, physical activity, and the risk of pancreatic cancer in the European prospective investigation into cancer and nutrition
    Amy Berrington de Gonzalez
    Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Roosevelt Drive, Oxford OX3 7LF, United Kingdom
    Cancer Epidemiol Biomarkers Prev 15:879-85. 2006
    ..50-1.35 for most active versus inactive). Future studies should consider including measurements of waist and hip circumference, to further investigate the relationship between central adiposity and the risk of pancreatic cancer...
  76. ncbi request reprint Occupational exposures, environmental tobacco smoke, and lung cancer
    Fabrizio Veglia
    Institute for Scientific Interchange ISI Foundation, Turin, Italy
    Epidemiology 18:769-75. 2007
    ..We have studied the association between 52 high-risk job titles and lung cancer incidence in a large prospective study, with more than 200,000 participants followed for more than 6 years and 809 incident cases of lung cancer...
  77. ncbi request reprint Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition
    Steffen Weikert
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Am J Epidemiol 167:438-46. 2008
    ..These results support the hypothesis that hypertension, rather than its medications, increases the risk of RCC in both sexes, while effective blood pressure control may lower the risk...
  78. ncbi request reprint Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study
    Timothy J Key
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Am J Clin Nutr 86:672-81. 2007
    ..Previous studies suggest that high plasma concentrations of carotenoids, retinol, or tocopherols may reduce the risk of prostate cancer...
  79. ncbi request reprint Dietary carbohydrates, glycemic index, glycemic load, and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition cohort
    Anne E Cust
    Nutrition and Hormones Unit, International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 166:912-23. 2007
    ....
  80. ncbi request reprint Cereal fiber intake may reduce risk of gastric adenocarcinomas: the EPIC-EURGAST study
    Mendez M A
    Department of Epidemiology, Catalan Institute of Oncology, Barcelona ICO IDIBELL, Spain
    Int J Cancer 121:1618-23. 2007
    ..Cereal fiber consumption may help to reduce risk of GC, particularly diffuse type tumors. Further study on different food sources of fiber in relation to GC risk is warranted to confirm these relationships...
  81. ncbi request reprint Eating out of home and its correlates in 10 European countries. The European Prospective Investigation into Cancer and Nutrition (EPIC) study
    Philippos Orfanos
    Department of Hygiene and Epidemiology, University of Athens Medical School, 75 Mikras Asias Street, Athens 11527, Greece
    Public Health Nutr 10:1515-25. 2007
    ....
  82. ncbi request reprint Serum androgens and prostate cancer among 643 cases and 643 controls in the European Prospective Investigation into Cancer and Nutrition
    Ruth C Travis
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Int J Cancer 121:1331-8. 2007
    ....
  83. ncbi request reprint The effect of occasional smoking on smoking-related cancers: in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Bine Kjøller Bjerregaard
    Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100, Copenhagen Ø, Denmark
    Cancer Causes Control 17:1305-9. 2006
    ..We have investigated the association between occasional smoking and cancer of the bladder, kidney, pancreas, upper aero-digestive tract and lung...
  84. ncbi request reprint Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition
    Olga M Sinilnikova
    IARC, Lyon, France
    Cancer Epidemiol Biomarkers Prev 16:409-15. 2007
    ..However, they suggest a possible role of the ACC-alpha common sequence variants in susceptibility to breast cancer and encourage studies of other genes involved in fatty acid synthesis...
  85. ncbi request reprint Physical activity and risk of endometrial cancer: the European prospective investigation into cancer and nutrition
    Christine Friedenreich
    Division of Population Health and Information, Alberta Cancer Board, Calgary, Alberta, Canada
    Int J Cancer 121:347-55. 2007
    ..The relative risk reductions are most apparent for household activities...
  86. ncbi request reprint An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes
    Matthias B Schulze
    German Institute of Human Nutrition Potsdam Rehbruecke, Department of Epidemiology, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    Diabetes Care 30:510-5. 2007
    ..We aimed to develop a precise risk score for the screening of large populations for individuals at high risk of developing type 2 diabetes based on noninvasive measurements of major risk factors in German study populations...
  87. ncbi request reprint Anthropometric factors and risk of endometrial cancer: the European prospective investigation into cancer and nutrition
    Christine Friedenreich
    Division of Population Health and Information, Alberta Cancer Board, T2N 4N2, Calgary, Alberta, Canada
    Cancer Causes Control 18:399-413. 2007
    ..To examine the association between anthropometry and endometrial cancer, particularly by menopausal status and exogenous hormone use subgroups...
  88. ncbi request reprint Association of carotenoids, tocopherols and vitamin C in plasma with allergic rhinitis and allergic sensitisation in adults
    Iris Kompauer
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Public Health Nutr 9:472-9. 2006
    ....
  89. doi request reprint CDH1 gene polymorphisms, smoking, Helicobacter pylori infection and the risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    Mazda Jenab
    International Agency for Research on Cancer IARC WHO, Lyon, France
    Eur J Cancer 44:774-80. 2008
    ..However, three CDH1 polymorphisms in the same haplotype block, including the CDH1-160C/A, interacted with smoking to increase GC risk in smokers but not in never smokers. These findings should be confirmed in larger independent studies...
  90. ncbi request reprint Intake of vegetables, legumes, and fruit, and risk for all-cause, cardiovascular, and cancer mortality in a European diabetic population
    Ute Nöthlings
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, 14558 Germany
    J Nutr 138:775-81. 2008
    ....
  91. ncbi request reprint No association between polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the risk of gastric adenocarcinoma in the European prospective investigation into cancer and nutrition
    Antonio Agudo
    Unit of Epidemiology Catalan Institute of Oncology, Av Gran Via s n km 2 7, 08907 L Hospitalet de Llobregat, Spain
    Cancer Epidemiol Biomarkers Prev 15:1043-5. 2006
  92. doi request reprint Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Julie A Britton
    Department of Epidemiology and Public Health, Imperial College London, Room 151, St Mary s Campus, Norfolk Place W2 1PG, London, UK
    Haematologica 93:1666-77. 2008
    ..It has been hypothesized that this may be due, in part, to the parallel rising prevalence of obesity. It is biologically plausible that anthropometric characteristics can infuence the risk of non-Hodgkin's lymphoma and multiple myeloma...
  93. doi request reprint Cross-sectional study on acrylamide hemoglobin adducts in subpopulations from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study
    Hubert W Vesper
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Agric Food Chem 56:6046-53. 2008
    ..In the assessment of potential health effects related to acrylamide exposure, country of origin, BMI, alcohol consumption, sex, and smoking status should be considered...
  94. ncbi request reprint Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition
    Antonio Agudo
    Unit of Epidemiology, Catalan Institute of Oncology, L Hospitalet de Llobregat, Av Gran Via s n km 2 7, 08907 Barcelona, Spain
    Cancer Epidemiol Biomarkers Prev 15:2427-34. 2006
    ..Most of these genes are involved in the activation and detoxification of polycyclic aromatic hydrocarbons, suggesting a potential role of these compounds in gastric carcinogenesis...
  95. ncbi request reprint Plasma and dietary vitamin C levels and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    Mazda Jenab
    Nutrition and Hormones Group, IARC WHO Lyon, France
    Carcinogenesis 27:2250-7. 2006
    ....
  96. pmc Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Naomi E Allen
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, UK
    Endocr Relat Cancer 15:485-97. 2008
    ..In conclusion, relatively high blood concentrations of estrogens and free testosterone are associated with an increased endometrial cancer risk in postmenopausal women...
  97. doi request reprint Circulating concentrations of folate and vitamin B12 in relation to prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutrition study
    Mattias Johansson
    Department of Surgical and Perioperative Sciences, Urology and Andrology, Umea University, 901 85 Umea, Sweden
    Cancer Epidemiol Biomarkers Prev 17:279-85. 2008
    ..The aim of the present study was to investigate the relationship between prostate cancer risk and circulating concentrations of folate and vitamin B(12) in a large prospective cohort...
  98. ncbi request reprint Dietary fat intake and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition
    Francesca L Crowe
    Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Am J Clin Nutr 87:1405-13. 2008
    ..However, the results from more recent prospective studies do not support this hypothesis, and the possible association between different food sources of fat and prostate cancer risk also remains unclear...
  99. ncbi request reprint Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC)
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition DIfE, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    J Natl Cancer Inst 98:920-31. 2006
    ..This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women...
  100. ncbi request reprint Intake of fruits and vegetables and risk of cancer of the upper aero-digestive tract: the prospective EPIC-study
    Heiner Boeing
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbrucke, Arthur Scheunert Allee 114 116, 14558, Nuthetal, Germany
    Cancer Causes Control 17:957-69. 2006
    ..Dietary recommendations should consider the potential benefit of increasing fruits and vegetables consumption for reducing the risk of cancers of the upper aero-digestive tract, particularly at low intake...
  101. ncbi request reprint Fruit and vegetable consumption and risk of epithelial ovarian cancer: the European Prospective Investigation into Cancer and Nutrition
    Mandy Schulz
    German Institute of Human Nutrition Potsdam Rehbrucke, Arthur Scheunert Allee 114 116, 14458 Nuthetal, Germany
    Cancer Epidemiol Biomarkers Prev 14:2531-5. 2005
    ..The association between consumption of fruit and vegetables and risk of ovarian cancer is still unclear from a prospective point of view...