U Haug

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. ncbi request reprint A simulation model for colorectal cancer screening: potential of stool tests with various performance characteristics compared with screening colonoscopy
    Ulrike Haug
    Department of Epidemiology, German Center for Research on Ageing, Bergheimer Strasse 20, Heidelberg 69115, Germany
    Cancer Epidemiol Biomarkers Prev 14:422-8. 2005
  2. pmc How should individuals with a false-positive fecal occult blood test for colorectal cancer be managed? A decision analysis
    Ulrike Haug
    Division of Preventive Oncology, National Center for Tumor Diseases German Cancer Research Center, DKFZ, Heidelberg, Germany
    Int J Cancer 131:2094-102. 2012
  3. doi request reprint Stool testing for the early detection of pancreatic cancer: rationale and current evidence
    Ulrike Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, Bergheimer Street 20, Heidelberg 69115, Germany
    Expert Rev Mol Diagn 8:753-9. 2008
  4. doi request reprint Is fecal occult blood testing more sensitive for left- versus right-sided colorectal neoplasia? A systematic literature review
    Ulrike Haug
    Division of Preventive Oncology, National Center for Tumor Diseases German Cancer Research Center DKFZ, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany
    Expert Rev Mol Diagn 11:605-16. 2011
  5. pmc Sensitivity of immunochemical faecal occult blood testing for detecting left- vs right-sided colorectal neoplasia
    U Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Im Neuenheimer Feld 460, Heidelberg 69120, Germany
    Br J Cancer 104:1779-85. 2011
  6. ncbi request reprint Mutant-enriched PCR and allele-specific hybridization reaction to detect K-ras mutations in stool DNA: high prevalence in a large sample of older adults
    Ulrike Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Clin Chem 53:787-90. 2007
  7. pmc Tumour M2-PK as a stool marker for colorectal cancer: comparative analysis in a large sample of unselected older adults vs colorectal cancer patients
    U Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center Bergheimer Street 20, 69115 Heidelberg, Germany
    Br J Cancer 96:1329-34. 2007
  8. doi request reprint Quantitative immunochemical fecal occult blood testing for colorectal adenoma detection: evaluation in the target population of screening and comparison with qualitative tests
    Ulrike Haug
    German Cancer Research Center, Heidelberg, Germany
    Am J Gastroenterol 105:682-90. 2010
  9. ncbi request reprint Blood markers for early detection of colorectal cancer: a systematic review
    Sabrina Hundt
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, Bergheimer Strasse 20, 69115 Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 16:1935-53. 2007
  10. pmc Sensitivity and specificity of faecal tumour M2 pyruvate kinase for detection of colorectal adenomas in a large screening study
    U Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, Heidelberg 69115, Germany
    Br J Cancer 99:133-5. 2008

Collaborators

Detail Information

Publications20

  1. ncbi request reprint A simulation model for colorectal cancer screening: potential of stool tests with various performance characteristics compared with screening colonoscopy
    Ulrike Haug
    Department of Epidemiology, German Center for Research on Ageing, Bergheimer Strasse 20, Heidelberg 69115, Germany
    Cancer Epidemiol Biomarkers Prev 14:422-8. 2005
    ....
  2. pmc How should individuals with a false-positive fecal occult blood test for colorectal cancer be managed? A decision analysis
    Ulrike Haug
    Division of Preventive Oncology, National Center for Tumor Diseases German Cancer Research Center, DKFZ, Heidelberg, Germany
    Int J Cancer 131:2094-102. 2012
    ..Specifying an appropriate management strategy for individuals with a prior fpFOBT may substantially reduce required resources within a FOBT-based CRC screening program without limiting its effectiveness...
  3. doi request reprint Stool testing for the early detection of pancreatic cancer: rationale and current evidence
    Ulrike Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, Bergheimer Street 20, Heidelberg 69115, Germany
    Expert Rev Mol Diagn 8:753-9. 2008
    ..Pertinent studies could greatly benefit from recent methodological advances gained in connection with stool testing for colorectal cancer...
  4. doi request reprint Is fecal occult blood testing more sensitive for left- versus right-sided colorectal neoplasia? A systematic literature review
    Ulrike Haug
    Division of Preventive Oncology, National Center for Tumor Diseases German Cancer Research Center DKFZ, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany
    Expert Rev Mol Diagn 11:605-16. 2011
    ..Most of the seven included studies showed a higher sensitivity of FOBT for advanced neoplasia in the left versus right colon, but this finding needs to be confirmed since the available literature is scarce and not entirely consistent...
  5. pmc Sensitivity of immunochemical faecal occult blood testing for detecting left- vs right-sided colorectal neoplasia
    U Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Im Neuenheimer Feld 460, Heidelberg 69120, Germany
    Br J Cancer 104:1779-85. 2011
    ..We aimed to assess the sensitivity of an immunochemical FOBT for detecting advanced colorectal neoplasia in the left vs the right colon and to explore reasons for potential differences in site-specific test performance...
  6. ncbi request reprint Mutant-enriched PCR and allele-specific hybridization reaction to detect K-ras mutations in stool DNA: high prevalence in a large sample of older adults
    Ulrike Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Clin Chem 53:787-90. 2007
    ..We investigated the prevalence and potential determinants of mutant K-ras in stool in a large sample of unselected older adults and assessed the association with colonoscopic findings...
  7. pmc Tumour M2-PK as a stool marker for colorectal cancer: comparative analysis in a large sample of unselected older adults vs colorectal cancer patients
    U Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center Bergheimer Street 20, 69115 Heidelberg, Germany
    Br J Cancer 96:1329-34. 2007
    ..Possibilities to enhance specificity of the test should be explored...
  8. doi request reprint Quantitative immunochemical fecal occult blood testing for colorectal adenoma detection: evaluation in the target population of screening and comparison with qualitative tests
    Ulrike Haug
    German Cancer Research Center, Heidelberg, Germany
    Am J Gastroenterol 105:682-90. 2010
    ....
  9. ncbi request reprint Blood markers for early detection of colorectal cancer: a systematic review
    Sabrina Hundt
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, Bergheimer Strasse 20, 69115 Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 16:1935-53. 2007
    ..The purpose of this review was to give an overview of published studies on blood markers aimed at the early detection of CRC and to summarize their performance characteristics...
  10. pmc Sensitivity and specificity of faecal tumour M2 pyruvate kinase for detection of colorectal adenomas in a large screening study
    U Haug
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, Heidelberg 69115, Germany
    Br J Cancer 99:133-5. 2008
    ..56 (0.52-0.59) for advanced and other adenomas, respectively. In conclusion, the tumour M2 PK test has only very limited potential to distinguish between people bearing precursors to CRC and people with no finding at colonoscopy...
  11. doi request reprint Colonoscopy use in a country with a long-standing colorectal cancer screening programme: evidence from a large German survey
    M Sieverding
    Department of Psychology, University of Heidelberg, Heidelberg, Germany
    Z Gastroenterol 48:1351-7. 2010
    ..We aimed to examine overall prevalence and correlates of colonoscopy use in Germany, a country with a long-standing, opportunistic CRC screening programme...
  12. doi request reprint [Screening: prerequisites]
    M Hoffmeister
    Abteilung Klinische Epidemiologie und Alternsforschung, Deutsches Krebsforschungszentrum, Bergheimer Strasse 20, 69115, Heidelberg, Germany
    Internist (Berl) 49:655-6, 658-9. 2008
    ..e. the diagnosis of clinically irrelevant disease). Benefits from screening must be achieved at acceptable costs. Implementation of screening has to be based on scientific evidence and accompanied by scientific evaluation...
  13. pmc Comparison and combination of blood-based inflammatory markers with faecal occult blood tests for non-invasive colorectal cancer screening
    S Tao
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Centre, Heidelberg, Germany
    Br J Cancer 106:1424-30. 2012
    ..Faecal occult blood tests (FOBTs) are widely used for colorectal cancer (CRC) screening. Blood-based inflammatory markers have been suggested as alternative or supplementary non-invasive CRC screening tests...
  14. pmc Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology
    H Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Strasse 20, Heidelberg D 69115, Germany
    Br J Cancer 99:532-5. 2008
    ..The ages at which defined levels of incidence and mortality were reached varied between 9 and 17 years between countries. This variation requires consideration in the definition of screening guidelines...
  15. doi request reprint Meta-analysis: longitudinal studies of serum vitamin D and colorectal cancer risk
    L Yin
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Strasse, Heidelberg D 69115, Germany
    Aliment Pharmacol Ther 30:113-25. 2009
    ..Further research has been conducted over the past 20 years...
  16. pmc Gender differences in colorectal cancer: implications for age at initiation of screening
    H Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Strasse 20, D 69115 Heidelberg, Germany
    Br J Cancer 96:828-31. 2007
    ..The gender differences were remarkably constant across populations and over time. These patterns suggest that gender differentiation of age at initiation may be worthwhile to utilise CRC-screening resources more efficiently...
  17. doi request reprint Evaluation of serum and urinary myeloid related protein-14 as a marker for early detection of prostate cancer
    Heiko Muller
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    J Urol 180:1309-12; discussion 1312-3. 2008
    ..In diagnostic studies promising results were shown for myeloid related protein-14 in serum and urine. However, confirmation in longitudinal population based studies is needed...
  18. pmc Risk of progression of advanced adenomas to colorectal cancer by age and sex: estimates based on 840,149 screening colonoscopies
    Hermann Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, D 69115 Heidelberg, Germany
    Gut 56:1585-9. 2007
    ..To derive age and sex specific estimates of transition rates from advanced adenomas to colorectal cancer by combining data of a nationwide screening colonoscopy registry and national data on colorectal cancer (CRC) incidence...
  19. ncbi request reprint Tumor M2 pyruvate kinase as a stool marker for colorectal cancer: stability at room temperature and implications for application in the screening setting
    Ulrike Haug
    Clin Chem 52:782-4. 2006
  20. ncbi request reprint New stool tests for colorectal cancer screening: a systematic review focusing on performance characteristics and practicalness
    Ulrike Haug
    Department of Epidemiology, German Centre for Research on Ageing, Heidelberg, Germany
    Int J Cancer 117:169-76. 2005
    ..g., the possibility of mailing the samples, is needed...