Florian Hahne

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. pmc Statistical methods and software for the analysis of highthroughput reverse genetic assays using flow cytometry readouts
    Florian Hahne
    Division of Molecular Genome Analysis, German Cancer Research Center, INF 580, 69120 Heidelberg, Germany
    Genome Biol 7:R77. 2006
  2. pmc Extending pathways based on gene lists using InterPro domain signatures
    Florian Hahne
    German Cancer Research Center, Molecular Genome Analysis, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
    BMC Bioinformatics 9:3. 2008
  3. ncbi request reprint High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins
    Mamatha Sauermann
    Division of Molecular Genome Analysis, German Cancer Research Centre, Heidelberg, Germany
    J Biomol Screen 12:510-20. 2007
  4. ncbi request reprint Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle
    Dorit Arlt
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Cancer Res 65:7733-42. 2005
  5. ncbi request reprint Modeling breast cell cycle regulation--overcoming drug resistance
    Dorit Arlt
    Div of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Conf Proc IEEE Eng Med Biol Soc 1:40-3. 2006
  6. pmc The LIFEdb database in 2006
    Alexander Mehrle
    Division Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Nucleic Acids Res 34:D415-8. 2006

Collaborators

Detail Information

Publications6

  1. pmc Statistical methods and software for the analysis of highthroughput reverse genetic assays using flow cytometry readouts
    Florian Hahne
    Division of Molecular Genome Analysis, German Cancer Research Center, INF 580, 69120 Heidelberg, Germany
    Genome Biol 7:R77. 2006
    ..The software is freely available in the Bioconductor package prada. The method permits analysis of large screens to detect the effects of molecular interventions in cellular systems...
  2. pmc Extending pathways based on gene lists using InterPro domain signatures
    Florian Hahne
    German Cancer Research Center, Molecular Genome Analysis, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
    BMC Bioinformatics 9:3. 2008
    ..This works by comparing InterPro domain signatures of the candidate gene lists with domain signatures of gene sets derived from known classifications, e.g. KEGG pathways...
  3. ncbi request reprint High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins
    Mamatha Sauermann
    Division of Molecular Genome Analysis, German Cancer Research Centre, Heidelberg, Germany
    J Biomol Screen 12:510-20. 2007
    ..The candidate proteins were all verified in an independent microscopy-based nuclear fragmentation assay, finally resulting in the identification of 6 apoptosis inducers...
  4. ncbi request reprint Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle
    Dorit Arlt
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Cancer Res 65:7733-42. 2005
    ..We have established a novel functional profiling strategy that links genomics to cell biology and showed its potential for discerning cancer relevant modulators of the cell cycle in the candidate lists from microarray studies...
  5. ncbi request reprint Modeling breast cell cycle regulation--overcoming drug resistance
    Dorit Arlt
    Div of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Conf Proc IEEE Eng Med Biol Soc 1:40-3. 2006
  6. pmc The LIFEdb database in 2006
    Alexander Mehrle
    Division Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Nucleic Acids Res 34:D415-8. 2006
    ..LIFEdb enables researchers to systematically select and characterize genes and proteins of interest, and presents data and information via its user-friendly web-based interface...