H Geyer

Summary

Affiliation: German Sport University
Country: Germany

Publications

  1. ncbi request reprint Analysis of non-hormonal nutritional supplements for anabolic-androgenic steroids - results of an international study
    H Geyer
    Institute of Biochemistry, German Sport University, Cologne, Germany
    Int J Sports Med 25:124-9. 2004
  2. ncbi request reprint Analysis of confiscated black market drugs using chromatographic and mass spectrometric approaches
    Mario Thevis
    Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    J Anal Toxicol 32:232-40. 2008
  3. doi request reprint Nutritional supplements cross-contaminated and faked with doping substances
    Hans Geyer
    Center for Preventive Doping Research, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany
    J Mass Spectrom 43:892-902. 2008
  4. ncbi request reprint 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties
    A Friedel
    Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sport University Cologne, 50927 Cologne, Germany
    Toxicol Lett 165:149-55. 2006
  5. ncbi request reprint Characterisation of the pharmacological profile of desoxymethyltestosterone (Madol), a steroid misused for doping
    P Diel
    Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sports University Cologne, 50927 Cologne, Germany
    Toxicol Lett 169:64-71. 2007
  6. doi request reprint The prohormone 19-norandrostenedione displays selective androgen receptor modulator (SARM) like properties after subcutaneous administration
    P Diel
    Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sports University Cologne, Carl Diem Weg 6, Cologne 50927, Germany
    Toxicol Lett 177:198-204. 2008
  7. doi request reprint Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing
    S Guddat
    Institute of Biochemistry and Center for Preventive Doping Research, German Sport University, Am Sportpark Muengersdorf 6, 50933, Cologne, Germany
    Anal Bioanal Chem 405:8285-94. 2013
  8. ncbi request reprint Identification of the aromatase inhibitor letrozole in urine by gas chromatography/mass spectrometry
    U Mareck
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Rapid Commun Mass Spectrom 19:3689-93. 2005
  9. ncbi request reprint Analytical strategies for the detection of non-labelled anabolic androgenic steroids in nutritional supplements
    M K Parr
    Institute of Biochemistry, German Sport University Cologne
    Food Addit Contam 21:632-40. 2004
  10. doi request reprint Clenbuterol - regional food contamination a possible source for inadvertent doping in sports
    S Guddat
    Institute of Biochemistry and Center of Preventive Doping Research, German Sport University Cologne, Germany
    Drug Test Anal 4:534-8. 2012

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Analysis of non-hormonal nutritional supplements for anabolic-androgenic steroids - results of an international study
    H Geyer
    Institute of Biochemistry, German Sport University, Cologne, Germany
    Int J Sports Med 25:124-9. 2004
    ..01 micro g/g up to 190 micro g/g. The administration of supplements containing nandrolone prohormones adding up to a total uptake of more than 1 micro g resulted in positive doping results for norandrosterone for several hours...
  2. ncbi request reprint Analysis of confiscated black market drugs using chromatographic and mass spectrometric approaches
    Mario Thevis
    Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    J Anal Toxicol 32:232-40. 2008
    ..Except for those drugs supposedly originating from so-called underground labs, fake packings were hardly or not distinguishable from original boxes by visual inspection...
  3. doi request reprint Nutritional supplements cross-contaminated and faked with doping substances
    Hans Geyer
    Center for Preventive Doping Research, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany
    J Mass Spectrom 43:892-902. 2008
    ..For the detection of new 'designer' steroids in nutritional supplements, mass spectrometric strategies (GC/MS, LC/MS/MS) are presented...
  4. ncbi request reprint 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties
    A Friedel
    Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sport University Cologne, 50927 Cologne, Germany
    Toxicol Lett 165:149-55. 2006
    ..It has to be assumed that consumption of this substance is associated with adverse side effects typical for this class of compounds. Therefore, a strict control of its ban is essential...
  5. ncbi request reprint Characterisation of the pharmacological profile of desoxymethyltestosterone (Madol), a steroid misused for doping
    P Diel
    Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sports University Cologne, 50927 Cologne, Germany
    Toxicol Lett 169:64-71. 2007
    ..Therefore, there is a need for a strict control of a possible misuse...
  6. doi request reprint The prohormone 19-norandrostenedione displays selective androgen receptor modulator (SARM) like properties after subcutaneous administration
    P Diel
    Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sports University Cologne, Carl Diem Weg 6, Cologne 50927, Germany
    Toxicol Lett 177:198-204. 2008
    ..This observation may have relevance with respect to therapeutic aspects but also doping prevention...
  7. doi request reprint Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing
    S Guddat
    Institute of Biochemistry and Center for Preventive Doping Research, German Sport University, Am Sportpark Muengersdorf 6, 50933, Cologne, Germany
    Anal Bioanal Chem 405:8285-94. 2013
    ....
  8. ncbi request reprint Identification of the aromatase inhibitor letrozole in urine by gas chromatography/mass spectrometry
    U Mareck
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Rapid Commun Mass Spectrom 19:3689-93. 2005
    ..The full-scan spectrum, diagnostic ions and a validation of the method for the analysis of bis-4-cyanophenylmethanol are presented...
  9. ncbi request reprint Analytical strategies for the detection of non-labelled anabolic androgenic steroids in nutritional supplements
    M K Parr
    Institute of Biochemistry, German Sport University Cologne
    Food Addit Contam 21:632-40. 2004
    ..For quantitative measurements of the steroids in nutritional supplements, deuterated internal standards of the specific steroids or standard addition are necessary to compensate for matrix effects...
  10. doi request reprint Clenbuterol - regional food contamination a possible source for inadvertent doping in sports
    S Guddat
    Institute of Biochemistry and Center of Preventive Doping Research, German Sport University Cologne, Germany
    Drug Test Anal 4:534-8. 2012
    ..1-8.8%), accuracy (89.5-102.5%) and mean recovery (81.4%). Clenbuterol was detectable in 22 (79%) of the analyzed samples, indicating a general food contamination problem despite an official clenbuterol prohibition in China for livestock...
  11. ncbi request reprint Long-term detection and identification of metandienone and stanozolol abuse in athletes by gas chromatography-high-resolution mass spectrometry
    W Schanzer
    Institute of Biochemistry, German Sports University, Cologne, Germany
    J Chromatogr B Biomed Appl 687:93-108. 1996
    ..V and VI were isolated using high-performance liquid chromatography (HPLC) fractionation...
  12. doi request reprint High-throughput screening for various classes of doping agents using a new 'dilute-and-shoot' liquid chromatography-tandem mass spectrometry multi-target approach
    S Guddat
    Institute of Biochemistry and Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany
    Drug Test Anal 3:836-50. 2011
    ..This straightforward and reliable approach accomplishes the combination of different screening procedures resulting in a high-throughput method that increases the efficiency of the labs daily work...
  13. ncbi request reprint Serum testosterone and urinary excretion of steroid hormone metabolites after administration of a high-dose zinc supplement
    K Koehler
    Institute of Biochemistry, German Research Centre of Elite Sport, German Sport University Cologne, Cologne, Germany
    Eur J Clin Nutr 63:65-70. 2009
    ....
  14. ncbi request reprint Identification of the aromatase inhibitor aminoglutethimide in urine by gas chromatography/mass spectrometry
    U Mareck
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Rapid Commun Mass Spectrom 16:2209-14. 2002
    ..Full mass spectra and diagnostic ions for the analysis of aminoglutethimide are presented...
  15. ncbi request reprint Proteases in doping control analysis
    M Thevis
    Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Cologne, Germany
    Int J Sports Med 28:545-9. 2007
    ....
  16. ncbi request reprint Tetrahydrogestrinone is a potent but unselective binding steroid and affects glucocorticoid signalling in the liver
    A Friedel
    Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sport University Cologne, Cologne, 50927 Colonge, Germany
    Toxicol Lett 164:16-23. 2006
    ..Therefore, it is conceivable that an intake will result in adverse side effects...
  17. ncbi request reprint Determination of therapeutics with growth-hormone secretagogue activity in human urine for doping control purposes
    Mario Thevis
    Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Rapid Commun Mass Spectrom 20:3393-402. 2006
    ..In both cases, the administered drug and the respective desmethylated metabolites were detected...
  18. doi request reprint Factors influencing the steroid profile in doping control analysis
    Ute Mareck
    Institute of Biochemistry, Center for Preventive Doping Research, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany
    J Mass Spectrom 43:877-91. 2008
    ....
  19. ncbi request reprint Screening for unknown synthetic steroids in human urine by liquid chromatography-tandem mass spectrometry
    Mario Thevis
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933, Cologne, Germany
    J Mass Spectrom 40:955-62. 2005
    ..Subsequent product ion scan experiments on precursor ions of peaks of unknown origin provided structural identification of the unknown compounds...
  20. doi request reprint Mass spectrometric determination of gonadotrophin-releasing hormone (GnRH) in human urine for doping control purposes by means of LC-ESI-MS/MS
    Andreas Thomas
    Center for Preventive Doping Research and Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50993 Cologne, Germany
    J Mass Spectrom 43:908-15. 2008
    ..5 pg/ml), precision (inter/intraday, < 20%) and accuracy (105%) using Des-pGlu(1)-GnRH as internal standard to control each sample preparation step...
  21. doi request reprint Determination of 13C/12C ratios of endogenous urinary steroids: method validation, reference population and application to doping control purposes
    Thomas Piper
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Koln, Germany
    Rapid Commun Mass Spectrom 22:2161-75. 2008
    ..In order to determine naturally occurring (13)C/(12)C ratios of all implemented steroids, a reference population of n = 61 subjects was measured to enable the calculation of reference limits for all relevant steroidal Delta values...
  22. doi request reprint [Doping control activities in Germany 1989-2006]
    Mario Thevis
    Zentrum für Präventive Dopingforschung Institut für Biochemie, Deutsche Sporthochschule Koln, Carl Diem Weg 6, 50933 Koln
    Med Klin (Munich) 103:282-98. 2008
    ..In light of recent doping scandals and confessions in 2007, a critical review of national antidoping actions is considered necessary...
  23. ncbi request reprint Detection of dehydroepiandrosterone misuse by means of gas chromatography- combustion-isotope ratio mass spectrometry
    Ute Mareck
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany koeln de
    Eur J Mass Spectrom (Chichester, Eng) 13:419-26. 2007
    ..These results should be taken into consideration in future discussions about threshold values for endogenous steroids in doping control...
  24. ncbi request reprint Identification of the aromatase inhibitors anastrozole and exemestane in human urine using liquid chromatography/tandem mass spectrometry
    Ute Mareck
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Rapid Commun Mass Spectrom 20:1954-62. 2006
    ..02 ng/mL; exemestane: 3.1 ng/mL; dihydroexemestane: 0.5 ng/mL), interday precisions (6.6-11.1%, 4.9-9.1% and 5.6-8.3% for low [10 ng/mL], medium [50 ng/mL] and high [100 ng/mL] concentration) and recoveries (ranged from 85-97%)...
  25. ncbi request reprint Clenbuterol marketed as dietary supplement
    Maria K Parr
    Centre for Preventive Doping Research, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Biomed Chromatogr 22:298-300. 2008
    ..The ingestion of these products containing additions of therapeutic drugs can lead to side effects and/or interactions with conventional medicines...
  26. ncbi request reprint Determination of Synacthen in human plasma using immunoaffinity purification and liquid chromatography/tandem mass spectrometry
    Mario Thevis
    Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Rapid Commun Mass Spectrom 20:3551-6. 2006
    ..Authentic plasma samples obtained from a patient undergoing a standard short Synacthen test were used to prove the applicability of the developed procedure...
  27. ncbi request reprint High amounts of 17-methylated anabolic-androgenic steroids in effervescent tablets on the dietary supplement market
    Maria K Parr
    Centre for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Biomed Chromatogr 21:164-8. 2007
    ..The quantitation of metandienone, norandrostenedione, and stanozolol was performed using HPLC-DAD...
  28. ncbi request reprint Identification of oral antidiabetics and their metabolites in human urine by liquid chromatography/tandem mass spectrometry--a matter for doping control analysis
    Mario Thevis
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, Cologne, Germany
    Rapid Commun Mass Spectrom 19:928-36. 2005
    ....
  29. ncbi request reprint Detection of manipulation in doping control urine sample collection: a multidisciplinary approach to determine identical urine samples
    Mario Thevis
    Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Anal Bioanal Chem 388:1539-43. 2007
    ..Application of a new multidisciplinary strategy employing common and new doping control assays enables the detection of urine substitution in sports drug testing...
  30. ncbi request reprint Doping-control analysis of the 5alpha-reductase inhibitor finasteride: determination of its influence on urinary steroid profiles and detection of its major urinary metabolite
    Mario Thevis
    Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Cologne, Germany
    Ther Drug Monit 29:236-47. 2007
    ....
  31. ncbi request reprint Determination of the origin of urinary norandrosterone traces by gas chromatography combustion isotope ratio mass spectrometry
    Moritz Hebestreit
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, Cologne, Germany
    Analyst 131:1021-6. 2006
    ..By comparing delta(13)C(VPDB)-values of androsterone as endogenous reference compound with NA, the origin of NA in doping control samples was determined as either endogenous or exogenous...
  32. ncbi request reprint Mass spectrometric identification and characterization of a new long-term metabolite of metandienone in human urine
    Wilhelm Schanzer
    Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Rapid Commun Mass Spectrom 20:2252-8. 2006
    ....
  33. ncbi request reprint Histomorphologic evaluation of extracorporeal shock wave therapy of the fourth metatarsal bone and the origin of the suspensory ligament in horses without lameness
    Andrea S Bischofberger
    Equine Hospital, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland
    Am J Vet Res 67:577-82. 2006
    ..To determine via histologic examination and scintigraphy the effect of focused extracorporeal shock wave therapy (ESWT) on normal bone and the bone-ligament interface in horses...
  34. ncbi request reprint Identification of fentanyl, alfentanil, sufentanil, remifentanil and their major metabolites in human urine by liquid chromatography/tandem mass spectrometry for doping control purposes
    Mario Thevis
    Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
    Eur J Mass Spectrom (Chichester, Eng) 11:419-27. 2005
    ....