Research Topics
| H GeyerSummaryAffiliation: German Sport University Country: Germany Publications
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Detail Information
Publications
Analysis of non-hormonal nutritional supplements for anabolic-androgenic steroids - results of an international studyH Geyer
Institute of Biochemistry, German Sport University, Cologne, Germany
Int J Sports Med 25:124-9. 2004..01 micro g/g up to 190 micro g/g. The administration of supplements containing nandrolone prohormones adding up to a total uptake of more than 1 micro g resulted in positive doping results for norandrosterone for several hours...- Analysis of confiscated black market drugs using chromatographic and mass spectrometric approachesMario Thevis
Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
J Anal Toxicol 32:232-40. 2008..Except for those drugs supposedly originating from so-called underground labs, fake packings were hardly or not distinguishable from original boxes by visual inspection... 
Nutritional supplements cross-contaminated and faked with doping substancesHans Geyer
Center for Preventive Doping Research, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany
J Mass Spectrom 43:892-902. 2008..For the detection of new 'designer' steroids in nutritional supplements, mass spectrometric strategies (GC/MS, LC/MS/MS) are presented...- Characterisation of the pharmacological profile of desoxymethyltestosterone (Madol), a steroid misused for dopingP Diel
Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sports University Cologne, 50927 Cologne, Germany
Toxicol Lett 169:64-71. 2007..Therefore, there is a need for a strict control of a possible misuse... - 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic propertiesA Friedel
Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sport University Cologne, 50927 Cologne, Germany
Toxicol Lett 165:149-55. 2006..It has to be assumed that consumption of this substance is associated with adverse side effects typical for this class of compounds. Therefore, a strict control of its ban is essential... - The prohormone 19-norandrostenedione displays selective androgen receptor modulator (SARM) like properties after subcutaneous administrationP Diel
Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sports University Cologne, Carl Diem Weg 6, Cologne 50927, Germany
Toxicol Lett 177:198-204. 2008..This observation may have relevance with respect to therapeutic aspects but also doping prevention... - Analytical strategies for the detection of non-labelled anabolic androgenic steroids in nutritional supplementsM K Parr
Institute of Biochemistry, German Sport University Cologne
Food Addit Contam 21:632-40. 2004..For quantitative measurements of the steroids in nutritional supplements, deuterated internal standards of the specific steroids or standard addition are necessary to compensate for matrix effects... - Identification of the aromatase inhibitor letrozole in urine by gas chromatography/mass spectrometryU Mareck
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Rapid Commun Mass Spectrom 19:3689-93. 2005..The full-scan spectrum, diagnostic ions and a validation of the method for the analysis of bis-4-cyanophenylmethanol are presented... - Clenbuterol - regional food contamination a possible source for inadvertent doping in sportsS Guddat
Institute of Biochemistry and Center of Preventive Doping Research, German Sport University Cologne, Germany
Drug Test Anal 4:534-8. 2012..1-8.8%), accuracy (89.5-102.5%) and mean recovery (81.4%). Clenbuterol was detectable in 22 (79%) of the analyzed samples, indicating a general food contamination problem despite an official clenbuterol prohibition in China for livestock... - Long-term detection and identification of metandienone and stanozolol abuse in athletes by gas chromatography-high-resolution mass spectrometryW Schanzer
Institute of Biochemistry, German Sports University, Cologne, Germany
J Chromatogr B Biomed Appl 687:93-108. 1996..V and VI were isolated using high-performance liquid chromatography (HPLC) fractionation... - High-throughput screening for various classes of doping agents using a new 'dilute-and-shoot' liquid chromatography-tandem mass spectrometry multi-target approachS Guddat
Institute of Biochemistry and Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany
Drug Test Anal 3:836-50. 2011..This straightforward and reliable approach accomplishes the combination of different screening procedures resulting in a high-throughput method that increases the efficiency of the labs daily work... - Serum testosterone and urinary excretion of steroid hormone metabolites after administration of a high-dose zinc supplementK Koehler
Institute of Biochemistry, German Research Centre of Elite Sport, German Sport University Cologne, Cologne, Germany
Eur J Clin Nutr 63:65-70. 2009.... - Tetrahydrogestrinone is a potent but unselective binding steroid and affects glucocorticoid signalling in the liverA Friedel
Center for Preventive Doping Research, Institute of Cardiovascular Research and Sports Medicine, Department of Molecular and Cellular Sports Medicine, German Sport University Cologne, Cologne, 50927 Colonge, Germany
Toxicol Lett 164:16-23. 2006..Therefore, it is conceivable that an intake will result in adverse side effects... - Proteases in doping control analysisM Thevis
Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Cologne, Germany
Int J Sports Med 28:545-9. 2007.... - Identification of the aromatase inhibitor aminoglutethimide in urine by gas chromatography/mass spectrometryU Mareck
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Rapid Commun Mass Spectrom 16:2209-14. 2002..Full mass spectra and diagnostic ions for the analysis of aminoglutethimide are presented... - Identification of oral antidiabetics and their metabolites in human urine by liquid chromatography/tandem mass spectrometry--a matter for doping control analysisMario Thevis
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, Cologne, Germany
Rapid Commun Mass Spectrom 19:928-36. 2005.... - Detection of dehydroepiandrosterone misuse by means of gas chromatography- combustion-isotope ratio mass spectrometryUte Mareck
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany koeln de
Eur J Mass Spectrom (Chichester, Eng) 13:419-26. 2007..These results should be taken into consideration in future discussions about threshold values for endogenous steroids in doping control... - [Doping control activities in Germany 1989-2006]Mario Thevis
Zentrum für Präventive Dopingforschung Institut für Biochemie, Deutsche Sporthochschule Koln, Carl Diem Weg 6, 50933 Koln
Med Klin (Munich) 103:282-98. 2008..In light of recent doping scandals and confessions in 2007, a critical review of national antidoping actions is considered necessary... - Determination of 13C/12C ratios of endogenous urinary steroids: method validation, reference population and application to doping control purposesThomas Piper
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Koln, Germany
Rapid Commun Mass Spectrom 22:2161-75. 2008..In order to determine naturally occurring (13)C/(12)C ratios of all implemented steroids, a reference population of n = 61 subjects was measured to enable the calculation of reference limits for all relevant steroidal Delta values... - Mass spectrometric determination of gonadotrophin-releasing hormone (GnRH) in human urine for doping control purposes by means of LC-ESI-MS/MSAndreas Thomas
Center for Preventive Doping Research and Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50993 Cologne, Germany
J Mass Spectrom 43:908-15. 2008..5 pg/ml), precision (inter/intraday, < 20%) and accuracy (105%) using Des-pGlu(1)-GnRH as internal standard to control each sample preparation step... - Factors influencing the steroid profile in doping control analysisUte Mareck
Institute of Biochemistry, Center for Preventive Doping Research, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany
J Mass Spectrom 43:877-91. 2008.... - Clenbuterol marketed as dietary supplementMaria K Parr
Centre for Preventive Doping Research, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Biomed Chromatogr 22:298-300. 2008..The ingestion of these products containing additions of therapeutic drugs can lead to side effects and/or interactions with conventional medicines... - High amounts of 17-methylated anabolic-androgenic steroids in effervescent tablets on the dietary supplement marketMaria K Parr
Centre for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Biomed Chromatogr 21:164-8. 2007..The quantitation of metandienone, norandrostenedione, and stanozolol was performed using HPLC-DAD... - Identification of the aromatase inhibitors anastrozole and exemestane in human urine using liquid chromatography/tandem mass spectrometryUte Mareck
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Rapid Commun Mass Spectrom 20:1954-62. 2006..02 ng/mL; exemestane: 3.1 ng/mL; dihydroexemestane: 0.5 ng/mL), interday precisions (6.6-11.1%, 4.9-9.1% and 5.6-8.3% for low [10 ng/mL], medium [50 ng/mL] and high [100 ng/mL] concentration) and recoveries (ranged from 85-97%)... - Mass spectrometric identification and characterization of a new long-term metabolite of metandienone in human urineWilhelm Schanzer
Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Rapid Commun Mass Spectrom 20:2252-8. 2006.... - Determination of the origin of urinary norandrosterone traces by gas chromatography combustion isotope ratio mass spectrometryMoritz Hebestreit
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, Cologne, Germany
Analyst 131:1021-6. 2006..By comparing delta(13)C(VPDB)-values of androsterone as endogenous reference compound with NA, the origin of NA in doping control samples was determined as either endogenous or exogenous... - Determination of therapeutics with growth-hormone secretagogue activity in human urine for doping control purposesMario Thevis
Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Rapid Commun Mass Spectrom 20:3393-402. 2006..In both cases, the administered drug and the respective desmethylated metabolites were detected... - Determination of Synacthen in human plasma using immunoaffinity purification and liquid chromatography/tandem mass spectrometryMario Thevis
Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Rapid Commun Mass Spectrom 20:3551-6. 2006..Authentic plasma samples obtained from a patient undergoing a standard short Synacthen test were used to prove the applicability of the developed procedure... - Screening for unknown synthetic steroids in human urine by liquid chromatography-tandem mass spectrometryMario Thevis
Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933, Cologne, Germany
J Mass Spectrom 40:955-62. 2005..Subsequent product ion scan experiments on precursor ions of peaks of unknown origin provided structural identification of the unknown compounds... - Detection of manipulation in doping control urine sample collection: a multidisciplinary approach to determine identical urine samplesMario Thevis
Center for Preventive Doping Research Institute of Biochemistry, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Anal Bioanal Chem 388:1539-43. 2007..Application of a new multidisciplinary strategy employing common and new doping control assays enables the detection of urine substitution in sports drug testing... - Doping-control analysis of the 5alpha-reductase inhibitor finasteride: determination of its influence on urinary steroid profiles and detection of its major urinary metaboliteMario Thevis
Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Cologne, Germany
Ther Drug Monit 29:236-47. 2007.... - Identification of fentanyl, alfentanil, sufentanil, remifentanil and their major metabolites in human urine by liquid chromatography/tandem mass spectrometry for doping control purposesMario Thevis
Institute of Biochemistry, German Sport University Cologne, Carl-Diem Weg 6, 50933 Cologne, Germany
Eur J Mass Spectrom (Chichester, Eng) 11:419-27. 2005.... - Histomorphologic evaluation of extracorporeal shock wave therapy of the fourth metatarsal bone and the origin of the suspensory ligament in horses without lamenessAndrea S Bischofberger
Equine Hospital, Vetsuisse Faculty, University of Zurich, , Switzerland
Am J Vet Res 67:577-82. 2006..No damage to bone or the bone-ligament interface should occur at the settings used in this study, and ESWT can therefore be administered safely in horses...