Karsten Geletneky

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. pmc Regression of advanced rat and human gliomas by local or systemic treatment with oncolytic parvovirus H-1 in rat models
    Karsten Geletneky
    Department of Neurological Surgery, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Neuro Oncol 12:804-14. 2010
  2. pmc Therapeutic implications of the enhanced short and long-term cytotoxicity of radiation treatment followed by oncolytic parvovirus H-1 infection in high-grade glioma cells
    Karsten Geletneky
    Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany
    Bioeng Bugs 1:429-33. 2010
  3. pmc Improved killing of human high-grade glioma cells by combining ionizing radiation with oncolytic parvovirus H-1 infection
    Karsten Geletneky
    Department of Neurosurgery, University of Heidelberg, Heidelberg 69120, Germany
    J Biomed Biotechnol 2010:350748. 2010
  4. ncbi request reprint Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing
    Marta Herrero Y Calle
    Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany
    Int J Cancer 109:76-84. 2004
  5. ncbi request reprint Antitumor vaccination of patients with glioblastoma multiforme: a pilot study to assess feasibility, safety, and clinical benefit
    Hans Herbert Steiner
    Department of Neurosurgery, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    J Clin Oncol 22:4272-81. 2004

Collaborators

Detail Information

Publications5

  1. pmc Regression of advanced rat and human gliomas by local or systemic treatment with oncolytic parvovirus H-1 in rat models
    Karsten Geletneky
    Department of Neurological Surgery, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Neuro Oncol 12:804-14. 2010
    ..The results presented here and the innocuousness of H-1PV for humans argue for the use of H-1PV as a powerful means to perform oncolytic therapy of malignant gliomas...
  2. pmc Therapeutic implications of the enhanced short and long-term cytotoxicity of radiation treatment followed by oncolytic parvovirus H-1 infection in high-grade glioma cells
    Karsten Geletneky
    Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany
    Bioeng Bugs 1:429-33. 2010
    ..A likely translation into current clinical treatment protocols is to use stereotactic radiation of non-resectable recurrent gliomas followed by intratumoral injection of H-1PV to harvest the synergistic effects of combination treatment...
  3. pmc Improved killing of human high-grade glioma cells by combining ionizing radiation with oncolytic parvovirus H-1 infection
    Karsten Geletneky
    Department of Neurosurgery, University of Heidelberg, Heidelberg 69120, Germany
    J Biomed Biotechnol 2010:350748. 2010
    ..To elucidate the influence of ionizing radiation (IR) on the oncolytic activity of Parvovirus H-1 (H-1PV) in human high-grade glioma cells...
  4. ncbi request reprint Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing
    Marta Herrero Y Calle
    Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany
    Int J Cancer 109:76-84. 2004
    ..These advantageous characteristics of H-1 virus infection of glioma cells, combined with the known low toxicity of H-1 virus in nontransformed cells, make parvovirus H-1 a promising candidate for oncolytic glioma therapy...
  5. ncbi request reprint Antitumor vaccination of patients with glioblastoma multiforme: a pilot study to assess feasibility, safety, and clinical benefit
    Hans Herbert Steiner
    Department of Neurosurgery, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    J Clin Oncol 22:4272-81. 2004
    ..Also, we determined the influence on progression-free survival and overall survival and on vaccination-induced antitumor reactivity...