Wulf Dröge

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. ncbi Free radicals in the physiological control of cell function
    Wulf Dröge
    Division of Immunochemistry, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Physiol Rev 82:47-95. 2002
  2. ncbi Autophagy and aging--importance of amino acid levels
    Wulf Dröge
    Division of Immunochemistry, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Mech Ageing Dev 125:161-8. 2004
  3. ncbi The deficit in low molecular weight thiols as a target for antiageing therapy
    Wulf Dröge
    Division of Redox Physiology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Curr Drug Targets 7:1505-12. 2006
  4. ncbi Oxidative stress and aging
    Wulf Dröge
    Tumor Immunology Program, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Adv Exp Med Biol 543:191-200. 2003
  5. ncbi Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidants
    Wulf Dröge
    Deutsches Krebsforschungszentrum, German Cancer Research Center DKFZ, Division of Immunochemistry, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Exp Gerontol 37:1333-45. 2002
  6. ncbi The plasma redox state and ageing
    Wulf Dröge
    Division of Immunochemistry, German Cancer Research Center DKFZ, Im Neuenheimer, Feld 280, 69120 Heidelberg, Germany
    Ageing Res Rev 1:257-78. 2002
  7. ncbi Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males
    Gabriel A Bonaterra
    Department of Anatomy and Cell Biology III, University of Heidelberg, Im Neuenheimer Feld 307, 69120, Heidelberg, Germany
    J Mol Med (Berl) 85:181-90. 2007
  8. ncbi Oxidative stress and ageing: is ageing a cysteine deficiency syndrome?
    Wulf Dröge
    Deutsches Krebsforschungszentrum Division of Redox Physiology and Aging Research Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Philos Trans R Soc Lond B Biol Sci 360:2355-72. 2005
  9. ncbi Cholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox status in hyperlipidemic subjects
    Ralf Kinscherf
    Department of Anatomy and Cell Biology III, Heidelberg University, Heidelberg, Germany
    Free Radic Biol Med 35:1286-92. 2003
  10. ncbi Increased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects
    Gabriel A Bonaterra
    Department of Anatomy and Cell Biology III, University of Heidelberg, Im Neuenheimer Feld 307, 69120 Heidelberg, Germany
    Free Radic Biol Med 38:235-42. 2005

Collaborators

  • Wulf Hildebrandt
  • Thomas L Schmitt
  • Bernd Sido
  • Thomas G Hofmann
  • Gabriel A Bonaterra
  • Ralf Kinscherf
  • Jürgen Metz
  • Hans Peter Deigner
  • Klaus A Dugi
  • Roland Sauer
  • Anne Bodens
  • Hans-Peter Deigner
  • Andreas Möller
  • Helmut Heinle
  • Dan Turcanu
  • Gerd Michel
  • Huseyin Sirma
  • Raoul Breitkreutz
  • M Lienhard Schmitz
  • Falk Roder
  • Hans Will
  • Konstantinos Cafaltzis
  • Sven Rueffer
  • Elisabeth Klimczak
  • Lutz Edler
  • Egon Werle
  • Giso Feussner
  • Jörg Kreuzer

Detail Information

Publications15

  1. ncbi Free radicals in the physiological control of cell function
    Wulf Dröge
    Division of Immunochemistry, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Physiol Rev 82:47-95. 2002
    ..There is growing evidence that aging involves, in addition, progressive changes in free radical-mediated regulatory processes that result in altered gene expression...
  2. ncbi Autophagy and aging--importance of amino acid levels
    Wulf Dröge
    Division of Immunochemistry, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Mech Ageing Dev 125:161-8. 2004
    ..Recent studies suggest that this decrease may result from an age-related increase in post-absorptive amino acid levels and/or from an increase in baseline insulin receptor signaling. If so, it is potentially reversible...
  3. ncbi The deficit in low molecular weight thiols as a target for antiageing therapy
    Wulf Dröge
    Division of Redox Physiology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Curr Drug Targets 7:1505-12. 2006
    ....
  4. ncbi Oxidative stress and aging
    Wulf Dröge
    Tumor Immunology Program, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Adv Exp Med Biol 543:191-200. 2003
    ....
  5. ncbi Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidants
    Wulf Dröge
    Deutsches Krebsforschungszentrum, German Cancer Research Center DKFZ, Division of Immunochemistry, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Exp Gerontol 37:1333-45. 2002
    ..Thiol antioxidants were found to ameliorate various aging-related processes but obviously ought to be used with caution in consideration of the oxidative environment of the blood...
  6. ncbi The plasma redox state and ageing
    Wulf Dröge
    Division of Immunochemistry, German Cancer Research Center DKFZ, Im Neuenheimer, Feld 280, 69120 Heidelberg, Germany
    Ageing Res Rev 1:257-78. 2002
    ....
  7. ncbi Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males
    Gabriel A Bonaterra
    Department of Anatomy and Cell Biology III, University of Heidelberg, Im Neuenheimer Feld 307, 69120, Heidelberg, Germany
    J Mol Med (Berl) 85:181-90. 2007
    ..The higher expressions of scavenger receptors, proinflammatory and oxidative stress-related genes of PBMCs are suggested to result mainly from hyperlipidemia and the accompanied increase of oxLDL concentrations...
  8. ncbi Oxidative stress and ageing: is ageing a cysteine deficiency syndrome?
    Wulf Dröge
    Deutsches Krebsforschungszentrum Division of Redox Physiology and Aging Research Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Philos Trans R Soc Lond B Biol Sci 360:2355-72. 2005
    ....
  9. ncbi Cholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox status in hyperlipidemic subjects
    Ralf Kinscherf
    Department of Anatomy and Cell Biology III, Heidelberg University, Heidelberg, Germany
    Free Radic Biol Med 35:1286-92. 2003
    ....
  10. ncbi Increased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects
    Gabriel A Bonaterra
    Department of Anatomy and Cell Biology III, University of Heidelberg, Im Neuenheimer Feld 307, 69120 Heidelberg, Germany
    Free Radic Biol Med 38:235-42. 2005
    ....
  11. ncbi Low intestinal glutamine level and low glutaminase activity in Crohn's disease: a rational for glutamine supplementation?
    Bernd Sido
    Department of Surgery, Ruprecht Karls University, Heidelberg, Germany
    Dig Dis Sci 51:2170-9. 2006
    ..In the colon, however, which does not use glutamine as its principal energy source, immune enhancement of inflammatory cells by glutamine increases oxidative tissue injury...
  12. ncbi Oxidative enhancement of insulin receptor signaling: experimental findings and clinical implications
    Wulf Dröge
    Tumor Immunology Program, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Antioxid Redox Signal 7:1071-7. 2005
    ..e., the HOMA-R index) at least under certain conditions. This effect may have therapeutic implications...
  13. ncbi Interdependent regulation of insulin receptor kinase activity by ADP and hydrogen peroxide
    Thomas L Schmitt
    Division of Immunochemistry, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    J Biol Chem 280:3795-801. 2005
    ....
  14. ncbi Hydrogen peroxide inhibits activity of the IGF-1 receptor kinase
    Thomas L Schmitt
    Division of Immunochemistry, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Redox Rep 11:105-9. 2006
    ..This reciprocal influence of physiologically relevant doses of hydrogen peroxide may have important implications on signal transduction of the closely related receptors for insulin and IGF-1...
  15. ncbi PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains
    Andreas Möller
    Division of Immunochemistry, German Cancer Research Center DKFZ, 69120 Heidelberg, Germany
    Cancer Res 63:4310-4. 2003
    ..Whereas the architecture of HIPK domains is PML independent, HIPK2-mediated enhancement of p53-dependent transcription, p53 serine 46 phosphorylation and the antiproliferative function of HIPK2 strictly rely on the presence of PML...