J Chang-Claude

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. ncbi request reprint Breastfeeding and breast cancer risk by age 50 among women in Germany
    J Chang-Claude
    Division of Epidemiology, Deutsches Krebsforschungs Zentrum, Heidelberg, Germany
    Cancer Causes Control 11:687-95. 2000
  2. ncbi request reprint Risk estimation as a decision-making tool for genetic analysis of the breast cancer susceptibility genes. EC Demonstration Project on Familial Breast Cancer
    J Chang-Claude
    Deutsches Krebsforschungszentrum, Division of Epidemiology, Heidelberg, Germany
    Dis Markers 15:53-65. 1999
  3. doi request reprint No evidence for variation in colorectal cancer risk associated with different types of postmenopausal hormone therapy
    M Hoffmeister
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Clin Pharmacol Ther 86:416-24. 2009
  4. ncbi request reprint Good agreement between physician and self-reported hormone therapy data in a case-control study
    S Kropp
    Department of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    J Clin Epidemiol 60:1280-7. 2007
  5. doi request reprint Polymorphism Thr160Thr in SRD5A1, involved in the progesterone metabolism, modifies postmenopausal breast cancer risk associated with menopausal hormone therapy
    R Hein
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany
    Breast Cancer Res Treat 131:653-61. 2012
  6. pmc Hormone replacement therapy, body mass, and the risk of colorectal cancer among postmenopausal women from Germany
    M Hoffmeister
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Br J Cancer 97:1486-92. 2007
  7. pmc Does a negative screening colonoscopy ever need to be repeated?
    H Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Centre, Heidelberg, Germany
    Gut 55:1145-50. 2006
  8. ncbi request reprint Low-to-moderate alcohol consumption and breast cancer risk by age 50 years among women in Germany
    S Kropp
    Department of Clinical Epidemiology, Deutsches Krebs-Forschungszentrum, Heidelberg, Germany
    Am J Epidemiol 154:624-34. 2001
  9. ncbi request reprint Low-dose oral contraceptives: protective effect on ovarian cancer risk
    J Royar
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Heidelberg, Germany
    Int J Cancer 95:370-4. 2001
  10. pmc Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer
    K Buck
    Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld 581, Heidelberg, Germany
    Br J Cancer 105:1151-7. 2011

Detail Information

Publications22

  1. ncbi request reprint Breastfeeding and breast cancer risk by age 50 among women in Germany
    J Chang-Claude
    Division of Epidemiology, Deutsches Krebsforschungs Zentrum, Heidelberg, Germany
    Cancer Causes Control 11:687-95. 2000
    ..Issues with regard to the timing of breastfeeding and effect modification by correlates of breastfeeding and other risk factors of breast cancer remain unresolved...
  2. ncbi request reprint Risk estimation as a decision-making tool for genetic analysis of the breast cancer susceptibility genes. EC Demonstration Project on Familial Breast Cancer
    J Chang-Claude
    Deutsches Krebsforschungszentrum, Division of Epidemiology, Heidelberg, Germany
    Dis Markers 15:53-65. 1999
    ..Due to the incomplete BRCA2 screening of the families, we cannot yet draw any conclusions with respect to the breast cancer only families...
  3. doi request reprint No evidence for variation in colorectal cancer risk associated with different types of postmenopausal hormone therapy
    M Hoffmeister
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Clin Pharmacol Ther 86:416-24. 2009
    ..40, 0.17-0.90) or with oral tablets (0.59, 0.39-0.90). In combination with estrogen, progestagens of the norethisterone and levonorgestrel families were associated with strong reduction in CRC risk...
  4. ncbi request reprint Good agreement between physician and self-reported hormone therapy data in a case-control study
    S Kropp
    Department of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    J Clin Epidemiol 60:1280-7. 2007
    ..In a population-based case-control study examining the effects of postmenopausal hormone therapy (HT) on breast cancer risk, the authors conducted a validation study comparing prescription data from gynecologists with self-reports...
  5. doi request reprint Polymorphism Thr160Thr in SRD5A1, involved in the progesterone metabolism, modifies postmenopausal breast cancer risk associated with menopausal hormone therapy
    R Hein
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany
    Breast Cancer Res Treat 131:653-61. 2012
    ..Postmenopausal breast cancer risk associated with combined therapy may be modified by genetic variation in SRD5A1. Further well-powered studies are, however, required to replicate our finding...
  6. pmc Hormone replacement therapy, body mass, and the risk of colorectal cancer among postmenopausal women from Germany
    M Hoffmeister
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Br J Cancer 97:1486-92. 2007
    ..The reasons for the inconsistency of results regarding the potential risk modifying effect of postmenopausal hormones in the association of BMI with CRC remain inconclusive and require further study...
  7. pmc Does a negative screening colonoscopy ever need to be repeated?
    H Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Centre, Heidelberg, Germany
    Gut 55:1145-50. 2006
    ..The aim of this study was to assess the long term risk of clinically manifest colorectal cancer among subjects with negative findings at colonoscopy...
  8. ncbi request reprint Low-to-moderate alcohol consumption and breast cancer risk by age 50 years among women in Germany
    S Kropp
    Department of Clinical Epidemiology, Deutsches Krebs-Forschungszentrum, Heidelberg, Germany
    Am J Epidemiol 154:624-34. 2001
    ..7, 1.6, and 0.7 for women with low, moderate, and high levels of education, respectively. These data suggest that low-level consumption of alcohol does not increase breast cancer risk in premenopausal women...
  9. ncbi request reprint Low-dose oral contraceptives: protective effect on ovarian cancer risk
    J Royar
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Heidelberg, Germany
    Int J Cancer 95:370-4. 2001
    ..Our study provides evidence that low-dose oral contraceptives confer substantial protection against the development of ovarian cancer...
  10. pmc Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer
    K Buck
    Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld 581, Heidelberg, Germany
    Br J Cancer 105:1151-7. 2011
    ..Lignans - oestrogenic substances present in various foods - are associated with postmenopausal breast cancer risk, but not much is known regarding their effects on survival...
  11. pmc Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer
    J Chang-Claude
    Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Br J Cancer 100:1680-6. 2009
    ..97, 95% CI: 1.11-3.52) for telangiectasia. Variants in the TP53 gene may therefore modify the risk of late skin toxicity after radiotherapy...
  12. ncbi request reprint Inherited genetic susceptibility to breast cancer
    J Chang-Claude
    Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    IARC Sci Publ 154:177-90. 2001
    ..At present, it seems unlikely that the genetic information at single polygenes will be clinically relevant for risk assessment and management...
  13. ncbi request reprint A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability
    C S Healey
    CRC Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK
    Nat Genet 26:362-4. 2000
    ..82 in females and 1.38 in males. Therefore, this variant of BRCA2 appears also to affect fetal survival in a sex-dependent manner...
  14. pmc Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study
    F Canzian
    International Agency for Research on Cancer, Lyon, France
    Br J Cancer 94:299-307. 2006
    ..Common genetic variation in these candidate genes does not play a major role in altering breast cancer risk in Caucasians...
  15. ncbi request reprint Lung fibre burden in lung cancer cases employed in the rock and slag wool industry
    K Soldan
    International Agency for Research on Cancer, Lyon, France
    Ann Occup Hyg 50:241-8. 2006
    ..To evaluate the relationship between estimated exposure to man-made vitreous fibres (MMVF) and to asbestos fibres and their concentration in the lung tissue of lung cancer cases amongst MMVF production workers...
  16. ncbi request reprint Postmenopausal serum androgens, oestrogens and breast cancer risk: the European prospective investigation into cancer and nutrition
    R Kaaks
    International Agency for Research on Cancer IARC WHO, Lyon, France
    Endocr Relat Cancer 12:1071-82. 2005
    ..The results from this study caution against the use of DHEA(S), or other androgens, for postmenopausal androgen replacement therapy...
  17. ncbi request reprint Cigar, pipe, and cigarette smoking and bladder cancer risk in European men
    A Pitard
    Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France
    Cancer Causes Control 12:551-6. 2001
    ..CONCLUSION: Our results suggest that smoking of cigars and pipe is carcinogenic to the urinary bladder, although the potency might be lower than for cigarettes...
  18. pmc Alcohol dehydrogenase 1B (ADH1B) genotype, alcohol consumption and breast cancer risk by age 50 years in a German case-control study
    C Lilla
    Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    Br J Cancer 92:2039-41. 2005
    ..1, 95% confidence interval (CI) 0.8-1.6 for ADH1B*1/*1 genotype vs 0.2, 95% CI 0.1-1.0 for ADH1B*2 carriers)...
  19. ncbi request reprint Haplotype sharing analysis using mantel statistics
    L Beckmann
    German Cancer Research Center DKFZ, DE 69120 Heidelberg, Germany
    Hum Hered 59:67-78. 2005
    ..We present a new approach based on Mantel statistics for spacetime clustering, which is developed in order to improve the power of haplotype sharing analysis for gene mapping in complex disease...
  20. pmc Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease
    N Hamajima
    Cancer Research UK Epidemiology Unit, Gibson Building, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    Br J Cancer 87:1234-45. 2002
    ....
  21. ncbi request reprint Estimating the sensitivity of a genetic test using gene-carrier probability estimates and its application in genetic counselling
    H Becher
    University of Heidelberg, Department of Tropical Hygiene and Public Health, Germany
    J Cancer Epidemiol Prev 7:13-9. 2002
    ..This information could be based on individual pedigree and family-history data, and a known genetic model for the disease of interest...
  22. ncbi request reprint Anthropometric factors and the risk of premenopausal breast cancer in Germany
    E Verla-Tebit
    Division of Clinical Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Eur J Cancer Prev 14:419-26. 2005
    ..Our findings are consistent with studies that found weight gain to be protective against premenopausal breast cancer and suggest that this effect may be more pronounced for women who were lean in adolescence and early adulthood...