Daniele Campa

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. pmc Bitter taste receptor polymorphisms and human aging
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 7:e45232. 2012
  2. doi request reprint Genetic susceptibility to pancreatic cancer and its functional characterisation: the PANcreatic Disease ReseArch (PANDoRA) consortium
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    Dig Liver Dis 45:95-9. 2013
  3. pmc A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Med Genet 11:88. 2010
  4. pmc Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    BMC Gastroenterol 10:112. 2010
  5. doi request reprint Variation in genes coding for AMP-activated protein kinase (AMPK) and breast cancer risk in the European Prospective Investigation on Cancer (EPIC)
    Daniele Campa
    Department of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Breast Cancer Res Treat 127:761-7. 2011
  6. doi request reprint A gene-wide investigation on polymorphisms in the ABCG2/BRCP transporter and susceptibility to colorectal cancer
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    Mutat Res 645:56-60. 2008
  7. doi request reprint Genetic variability of the forkhead box O3 and prostate cancer risk in the European Prospective Investigation on Cancer
    Daniele Campa
    German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Oncol Rep 26:979-86. 2011
  8. doi request reprint ABO blood groups and pancreatic cancer risk and survival: results from the PANcreatic Disease ReseArch (PANDoRA) consortium
    Cosmeri Rizzato
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    Oncol Rep 29:1637-44. 2013
  9. doi request reprint Interaction between functional polymorphic variants in cytokine genes, established risk factors and susceptibility to basal cell carcinoma of skin
    Cosmeri Rizzato
    German Cancer Research Center DKFZ, 69120 Heidelberg, Germany
    Carcinogenesis 32:1849-54. 2011
  10. doi request reprint Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC)
    Daniele Campa
    German Cancer Research Center, DKFZ, Heidelberg, Germany
    Eur J Cancer 47:420-7. 2011

Detail Information

Publications25

  1. pmc Bitter taste receptor polymorphisms and human aging
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 7:e45232. 2012
    ..These data provide suggestive evidence on the possible correlation between human longevity and taste genetics...
  2. doi request reprint Genetic susceptibility to pancreatic cancer and its functional characterisation: the PANcreatic Disease ReseArch (PANDoRA) consortium
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    Dig Liver Dis 45:95-9. 2013
    ..The recruitment of additional collaborators and partner institutions is continuously on-going...
  3. pmc A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Med Genet 11:88. 2010
    ..TAS2R14 is one of the better characterized members of the taste receptor family and has several polymorphic variants. Several substances that have been shown to activate TAS2R14 are powerful toxic and carcinogenic agents...
  4. pmc Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    BMC Gastroenterol 10:112. 2010
    ..Accumulating evidence also indicates a role of ghrelin in cancer development...
  5. doi request reprint Variation in genes coding for AMP-activated protein kinase (AMPK) and breast cancer risk in the European Prospective Investigation on Cancer (EPIC)
    Daniele Campa
    Department of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Breast Cancer Res Treat 127:761-7. 2011
    ..We observed no statistically significant association between the SNPs in the PRKAs genes and BC risk and BMI after correction for multiple testing...
  6. doi request reprint A gene-wide investigation on polymorphisms in the ABCG2/BRCP transporter and susceptibility to colorectal cancer
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    Mutat Res 645:56-60. 2008
    ..56-0.94; P(value)=0.017), and 0.72 (95% CI 0.53-0.97; P(value)=0.03). Thus, we found no strong and clearcut association between ABCG2 polymorphisms and CRC risk. To our knowledge this is the first report on ABCG2 and CRC risk...
  7. doi request reprint Genetic variability of the forkhead box O3 and prostate cancer risk in the European Prospective Investigation on Cancer
    Daniele Campa
    German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Oncol Rep 26:979-86. 2011
    ..We conclude that polymorphisms in the FOXO3 gene that are associated with longevity are not major risk factors for PC risk, in this population of Caucasian men...
  8. doi request reprint ABO blood groups and pancreatic cancer risk and survival: results from the PANcreatic Disease ReseArch (PANDoRA) consortium
    Cosmeri Rizzato
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    Oncol Rep 29:1637-44. 2013
    ..In addition, we investigated the possible influence that genetic variability at the ABO locus may have in pancreatic cancer survival, but we observed no effect in our population...
  9. doi request reprint Interaction between functional polymorphic variants in cytokine genes, established risk factors and susceptibility to basal cell carcinoma of skin
    Cosmeri Rizzato
    German Cancer Research Center DKFZ, 69120 Heidelberg, Germany
    Carcinogenesis 32:1849-54. 2011
    ..53, 95% CI 0.34-0.82, P = 0.0019). In conclusion, we found that two polymorphisms in inflammatory genes interacting with environmental risk factors could modulate BCC risk...
  10. doi request reprint Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC)
    Daniele Campa
    German Cancer Research Center, DKFZ, Heidelberg, Germany
    Eur J Cancer 47:420-7. 2011
    ..None of the SNPs reached statistical significance after adjusting for multiple comparisons. Common SNPs in the fatty acid synthase pathway are not major contributors to prostate cancer risk...
  11. doi request reprint Polymorphisms in regulators of xenobiotic transport and metabolism genes PXR and CAR do not affect multiple myeloma risk: a case-control study in the context of the IMMEnSE consortium
    Alessandro Martino
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    J Hum Genet 58:155-9. 2013
    ..We can therefore exclude that common genetic variants in the xenobiotic transport and metabolism regulator genes PXR and CAR affect MM risk...
  12. doi request reprint Lack of replication of seven pancreatic cancer susceptibility loci identified in two Asian populations
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 22:320-3. 2013
    ..Two recent genome-wide association studies (GWAS) of pancreatic ductal adenocarcinoma (PDAC), conducted, respectively, in a Japanese and in a Chinese population, identified eight novel loci affecting PDAC risk...
  13. pmc Pancreatic cancer susceptibility loci and their role in survival
    Cosmeri Rizzato
    German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 6:e27921. 2011
    ..In conclusion, we found that rs8028529 could be, if these results are replicated, a promising marker for both risk and prognosis for this lethal disease...
  14. doi request reprint Could polymorphisms in ATP-binding cassette C3/multidrug resistance associated protein 3 (ABCC3/MRP3) modify colorectal cancer risk?
    Daniele Campa
    German Cancer Research Center, 69120 Heidelberg, Germany
    Eur J Cancer 44:854-7. 2008
    ..We did not find any significant association between the two ABCC3 polymorphisms and colorectal cancer risk...
  15. pmc A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 7:e32784. 2012
    ..In conclusion, in this study of about 8,800 individuals we show that ABCB1 gene polymorphisms play at best a minor role in the susceptibility to CRC...
  16. pmc Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC)
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 6:e16914. 2011
    ..In conclusion, we found an association with prostate cancer risk for two SNPs belonging to PRKCI, a gene which is frequently overexpressed in various neoplasms, including prostate cancer...
  17. pmc The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk
    Daniele Campa
    German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Cancer 10:563. 2010
    ..BMI is considered to be one of the measures of choice to evaluate body fatness and there is evidence that body fatness is related with an increased risk of breast cancer (BC)...
  18. pmc Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center Deutsches Krebsforschungszentrum DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    J Natl Cancer Inst 103:1252-63. 2011
    ..Relatively little is known about the possible interactions between these loci and the established risk factors for breast cancer...
  19. pmc Somatic mutations in exocrine pancreatic tumors: association with patient survival
    P Sivaramakrishna Rachakonda
    Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany
    PLoS ONE 8:e60870. 2013
    ..02) and a corresponding HR of 3.07 (95%CI 1.33-7.10). Our results are indicative of an association between mutational status and survival in PDAC patients, which if confirmed in subsequent studies can have potential clinical application...
  20. doi request reprint A comprehensive study of polymorphisms in ABCB1, ABCC2 and ABCG2 and lung cancer chemotherapy response and prognosis
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    Int J Cancer 131:2920-8. 2012
    ....
  21. doi request reprint POMC and TP53 genetic variability and risk of basal cell carcinoma of skin: Interaction between host and genetic factors
    Cosmeri Rizzato
    German Cancer Research Center DKFZ, Heidelberg, Germany
    J Dermatol Sci 63:47-54. 2011
    ..Malfunction of the p53 pathway is an almost universal hallmark of human tumors. Polymorphisms in the gene encoding p53 (TP53) alter its transcriptional activity, which in turn may influence the UV radiation-induced tanning response...
  22. pmc A comprehensive study of polymorphisms in the ABCB1, ABCC2, ABCG2, NR1I2 genes and lymphoma risk
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center, Heidelberg, Germany
    Int J Cancer 131:803-12. 2012
    ..0004), which could be replicated in an independent population. These results suggest a role for this gene in B-NHL susceptibility, especially for CLL...
  23. doi request reprint Genetic variation in genes of the fatty acid synthesis pathway and breast cancer risk
    Daniele Campa
    Department of Cancer Epidemiology, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
    Breast Cancer Res Treat 118:565-74. 2009
    ..On the other hand, we found that two SNPs in FASN were associated with BMI...
  24. ncbi request reprint Comprehensive investigation of genetic variation in the 8q24 region and multiple myeloma risk in the IMMEnSE consortium
    Daniele Campa
    Genomic Epidemiology Group, German Cancer Research Center DKFZ, Heidelberg, Germany
    Br J Haematol 157:331-8. 2012
    ..These data provide further evidence that the genetic variability in the 8q24 region is associated with cancer risk, particularly haematological malignancies...
  25. doi request reprint A genome-wide "pleiotropy scan" does not identify new susceptibility Loci for estrogen receptor negative breast cancer
    Daniele Campa
    Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 9:e85955. 2014
    ..049 to 2.3×10(-4). None of the variants reached statistical significance in the replication phase. In conclusion, this study did not identify any novel susceptibility loci for ER-breast cancer using a "pleiotropic approach". ..