Lutz P Breitling

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. pmc Liver enzymes: interaction analysis of smoking with alcohol consumption or BMI, comparing AST and ALT to γ-GT
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research C070, German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 6:e27951. 2011
  2. doi Smoking cessation and variations in nicotinic acetylcholine receptor subunits alpha-5, alpha-3, and beta-4 genes
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Biol Psychiatry 65:691-5. 2009
  3. doi Dopamine-related genes and spontaneous smoking cessation in ever-heavy smokers
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, TP4 INF581, 69120 Heidelberg, Germany
    Pharmacogenomics 12:1099-106. 2011
  4. doi Gamma-glutamyltransferase, general and cause-specific mortality in 19,000 construction workers followed over 20 years
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, D 69120 Heidelberg, Germany
    J Hepatol 55:594-601. 2011
  5. doi Prospective association of dopamine-related polymorphisms with smoking cessation in general care
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, D 69115 Heidelberg, Germany
    Pharmacogenomics 11:527-36. 2010
  6. doi Gamma-glutamyltransferase and prognosis in patients with stable coronary heart disease followed over 8 years
    L P Breitling
    Division of Clinical Epidemiology and Aging Research C070, German Cancer Research Center, Bergheimer Str 20, 69115 Heidelberg, Germany
    Atherosclerosis 210:649-55. 2010
  7. doi Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Hepatology 49:802-8. 2009
  8. doi Odd odds interactions introduced through dichotomisation of continuous outcomes
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, D 69115 Heidelberg, Germany
    J Epidemiol Community Health 64:300-3. 2010
  9. doi Situational temptation scores and smoking cessation in general care
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Psychol Addict Behav 23:362-7. 2009
  10. doi Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study
    Bob Siegerink
    German Cancer Research Center DKFZ, Division of Clinical Epidemiology and Aging Research C070, Heidelberg, Germany
    Clin Res Cardiol 102:193-202. 2013

Detail Information

Publications22

  1. pmc Liver enzymes: interaction analysis of smoking with alcohol consumption or BMI, comparing AST and ALT to γ-GT
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research C070, German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 6:e27951. 2011
    ..The present work aimed to provide further insights by examining similar interactions pertaining to aspartate and alanine transaminase (AST, ALT), routine liver markers less prone to enzyme induction...
  2. doi Smoking cessation and variations in nicotinic acetylcholine receptor subunits alpha-5, alpha-3, and beta-4 genes
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Biol Psychiatry 65:691-5. 2009
    ..We aimed to determine whether these genetic variations are also predictive of smoking cessation...
  3. doi Dopamine-related genes and spontaneous smoking cessation in ever-heavy smokers
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, TP4 INF581, 69120 Heidelberg, Germany
    Pharmacogenomics 12:1099-106. 2011
    ..Several studies have provided evidence for associations of polymorphisms located in and near dopamine-related genes and nicotine dependence and other smoking-related phenotypes, including pharmacogenetic interactions...
  4. doi Gamma-glutamyltransferase, general and cause-specific mortality in 19,000 construction workers followed over 20 years
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, D 69120 Heidelberg, Germany
    J Hepatol 55:594-601. 2011
    ..The present study attempted to expand the body of evidence to especially relevant occupational cohorts in which exposure to established γ-GT determinants may greatly differ from the general population...
  5. doi Prospective association of dopamine-related polymorphisms with smoking cessation in general care
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, D 69115 Heidelberg, Germany
    Pharmacogenomics 11:527-36. 2010
    ..Genetic contributions to nicotine dependence have been demonstrated repeatedly, but the relevance of individual polymorphisms for smoking cessation remains controversial...
  6. doi Gamma-glutamyltransferase and prognosis in patients with stable coronary heart disease followed over 8 years
    L P Breitling
    Division of Clinical Epidemiology and Aging Research C070, German Cancer Research Center, Bergheimer Str 20, 69115 Heidelberg, Germany
    Atherosclerosis 210:649-55. 2010
    ..Serum gamma-glutamyltransferase (gamma-GT) predicts incident cardiovascular disease and mortality. The present study examined whether gamma-GT also is associated with prognosis in patients with stable coronary heart disease...
  7. doi Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Hepatology 49:802-8. 2009
    ..9 (1.1-7.6) in women and to 3.8 (2.2-6.6) in men (test for interaction between alcohol consumption and smoking: P(females) = 0.12, P(males) = 0.0017)...
  8. doi Odd odds interactions introduced through dichotomisation of continuous outcomes
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, D 69115 Heidelberg, Germany
    J Epidemiol Community Health 64:300-3. 2010
    ..We were interested in the effects of dichotomisation of an outcome variable when two predictors are examined...
  9. doi Situational temptation scores and smoking cessation in general care
    Lutz Philipp Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Psychol Addict Behav 23:362-7. 2009
    ..Additional studies are needed to fully understand how situational temptations relate to smoking cessation outcomes and explain variance beyond that of more established predictors of cessation...
  10. doi Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study
    Bob Siegerink
    German Cancer Research Center DKFZ, Division of Clinical Epidemiology and Aging Research C070, Heidelberg, Germany
    Clin Res Cardiol 102:193-202. 2013
    ..This study aimed to determine the associations of both ADMA and SDMA levels with secondary cardiovascular disease events and all-cause mortality in patients with stable coronary heart disease (CHD)...
  11. doi Genetic variations in the vitamin D binding protein and season-specific levels of vitamin D among older adults
    Laura Perna
    German Cancer Research Center DKFZ, Division of Clinical Epidemiology and Aging Research, Im Neuenheimer Feld 581, Heidelberg, Germany
    Epidemiology 24:104-9. 2013
    ..The quantification of this association among older women and men and its potential variation by season remain unexplored...
  12. doi Impact of national smoke-free legislation on home smoking bans: findings from the International Tobacco Control Policy Evaluation Project Europe Surveys
    Ute Mons
    German Cancer Research Center, Unit Cancer Prevention and WHO Collaborating Centre for Tobacco Control, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Tob Control 22:e2-9. 2013
    ..To measure changes in prevalence and predictors of home smoking bans (HSBs) among smokers in four European countries after the implementation of national smoke-free legislation...
  13. doi Vitamin D and cognitive functioning in the elderly population in Germany
    Lutz P Breitling
    Division C070 Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Exp Gerontol 47:122-7. 2012
    ..To examine the relationship of serum 25-hydroxy vitamin D3 with cognitive functioning in higher age, using an instrument covering multiple cognitive domains in a population-based study...
  14. pmc Type II secretory phospholipase A2 and prognosis in patients with stable coronary heart disease: mendelian randomization study
    Lutz P Breitling
    Division C070 Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, Heidelberg, Germany
    PLoS ONE 6:e22318. 2011
    ..This study investigated if an association of sPLA(2)-IIa with secondary cardiovascular disease (CVD) events may be of causal nature or mainly a matter of confounding by correlated cardiovascular risk markers...
  15. doi Large-scale application of a telephone-based test of cognitive functioning in older adults
    Lutz P Breitling
    German Cancer Research Center, Heidelberg, Germany
    Dement Geriatr Cogn Disord 30:309-16. 2010
    ..The present study examined the practicability of such investigations using a recently developed telephone interview (Cognitive Telephone Screening Instrument, COGTEL)...
  16. doi Association of hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) variants and colorectal cancer risk
    Bernd Frank
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
    Carcinogenesis 32:190-6. 2011
    ..82, 95% CI = 0.70, 0.95, P = 0.01) as well as among smokers (OR = 0.74, 95% CI = 0.61, 0.90, P = 0.003). Yet, our data do not support the previously reported associations of HPGD tagSNPs and risk of CRC...
  17. doi Prognostic usefulness of free fatty acids in patients with stable coronary heart disease
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research C070, German Cancer Research Center, Heidelberg, Germany
    Am J Cardiol 108:508-13. 2011
    ..02, for 95th percentile vs first quartile). In conclusion, FFAs are closely correlated with cardiovascular risk markers, and in particular, very high FFA might identify patients with stable coronary heart disease with worse prognoses...
  18. pmc Comprehensive smoke-free policies attract more support from smokers in Europe than partial policies
    Ute Mons
    Unit Cancer Prevention and WHO Collaborating Centre for Tobacco Control, German Cancer Research Center, DKFZ, Heidelberg, Germany
    Eur J Public Health 22:10-6. 2012
    ..Support for smoke-free policies increases over time and particularly after implementation of the policy. In this study we examined whether the comprehensiveness of such policies moderates the effect on support among smokers...
  19. ncbi The novel "genomic pathway approach" to complex diseases: a reason for (over-)optimism?
    Lutz P Breitling
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer St 20, D 69115 Heidelberg, Germany
    Epidemiology 20:500-7. 2009
    ....
  20. doi Vitamin D and cardiovascular disease: systematic review and meta-analysis of prospective studies
    Norma C Grandi
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, D 69115 Heidelberg, Germany
    Prev Med 51:228-33. 2010
    ..This review summarizes evidence from prospective studies evaluating the prognostic value of 25-OH-D for cardiovascular disease incidence and mortality...
  21. pmc Tobacco-smoking-related differential DNA methylation: 27K discovery and replication
    Lutz P Breitling
    Division C070 Clinical Epidemiology and Aging Research, German Cancer Research Center, D 69120 Heidelberg, Germany
    Am J Hum Genet 88:450-7. 2011
    ..To date, this gene had not attracted attention in the literature on smoking...