Marco Breinig

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. ncbi Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors
    Marco Breinig
    Department of General Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Clin Cancer Res 17:2237-49. 2011
  2. ncbi Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors?
    Frank Bergmann
    Institute of Pathology, University of Heidelberg, Heidelberg, Germany
    Am J Gastroenterol 104:171-81. 2009
  3. ncbi Her2 overexpression is a rare event in anorectal melanoma
    Burkhard Maria Helmke
    Department of General Pathology, Heidelberg University Hospital, Heidelberg, Germany
    Melanoma Res 20:431-4. 2010
  4. ncbi Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms
    Benjamin Goeppert
    Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Hepatology 52:2023-33. 2010
  5. ncbi Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma
    Marco Breinig
    Department of General Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Hepatology 50:102-12. 2009

Collaborators

Detail Information

Publications5

  1. ncbi Heat shock protein 90-sheltered overexpression of insulin-like growth factor 1 receptor contributes to malignancy of thymic epithelial tumors
    Marco Breinig
    Department of General Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Clin Cancer Res 17:2237-49. 2011
    ..Consequently, there is a lack of efficacious targeted therapies and patient prognosis remains dismal, particularly for advanced TEMs. We sought to investigate protumorigenic mechanism relevant to this understudied cancer...
  2. ncbi Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors?
    Frank Bergmann
    Institute of Pathology, University of Heidelberg, Heidelberg, Germany
    Am J Gastroenterol 104:171-81. 2009
    ....
  3. ncbi Her2 overexpression is a rare event in anorectal melanoma
    Burkhard Maria Helmke
    Department of General Pathology, Heidelberg University Hospital, Heidelberg, Germany
    Melanoma Res 20:431-4. 2010
    ..The results presented here show that isolated cases of AM may benefit from an additive Her2-directed therapy, as the overexpression of Her2 was found in one of our AM patients...
  4. ncbi Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms
    Benjamin Goeppert
    Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Hepatology 52:2023-33. 2010
    ..Conclusion: In addition to genetic alterations, epigenetic mechanisms are responsible for the reduction of the tumor suppressor gene AKAP12 in human hepatocarcinogenesis...
  5. ncbi Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma
    Marco Breinig
    Department of General Pathology, University Hospital Heidelberg, Heidelberg, Germany
    Hepatology 50:102-12. 2009
    ..Conclusion: Hsp90 constitutes a promising therapeutic target in HCC. Non-quinone Hsp90 inhibitors exhibit tumor-specific accumulation and exert potent antineoplastic activity without causing significant hepatotoxicity...