N Becker

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. ncbi [Development of the incidence and mortality of breast cancer]
    N Becker
    Abteilung Klinische Epidemiologie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg
    Radiologe 41:337-43. 2001
  2. ncbi Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort
    Alexandra Nieters
    German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Eur J Nutr 41:210-21. 2002
  3. ncbi Cancer mortality in a cohort of male German iron foundry workers
    Karl Heinrich Adzersen
    German Cancer Research Center DKFZ, Division of Clinical Epidemiology, Heidelberg, Germany
    Am J Ind Med 43:295-305. 2003
  4. ncbi [Epidemiology of colorectal cancer]
    N Becker
    Abteilung Klinische Epidemiologie, Deutsches Krebsforschungszentrum, Heidelberg
    Radiologe 43:98-104. 2003
  5. ncbi [Experiences in scientific use of data from cancer registries]
    N Becker
    Deutsches Krebsforschungszentrum, Heidelberg
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:444-50. 2004
  6. doi [Active monitoring of cancer clusters: comments from an epidemiological perspective]
    N Becker
    Epidemiologisches Krebsregister Baden Württemberg, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 581, 69120, Heidelberg, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57:41-6. 2014
  7. doi Hepatitis B virus infection is associated with deletion of chromosome 8p in multiple myeloma
    Nikolaus Becker
    Clinical Cancer Registry, National Center of Tumor Diseases and German Cancer Research Center, Im Neuenheimer Feld 581, Heidelberg, Germany
    Eur J Haematol 90:279-85. 2013
  8. doi Hepatitis B virus infection and risk of lymphoma: results of a serological analysis within the European case-control study Epilymph
    Nikolaus Becker
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany
    J Cancer Res Clin Oncol 138:1993-2001. 2012
  9. doi Randomized study on early detection of lung cancer with MSCT in Germany: study design and results of the first screening round
    N Becker
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany
    J Cancer Res Clin Oncol 138:1475-86. 2012
  10. ncbi Evaluation of effectiveness of quality-assured mammography screening in Germany: sample size considerations and design options
    Nikolaus Becker
    German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg, Germany
    Eur J Cancer Prev 16:225-31. 2007

Detail Information

Publications81

  1. ncbi [Development of the incidence and mortality of breast cancer]
    N Becker
    Abteilung Klinische Epidemiologie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg
    Radiologe 41:337-43. 2001
    ....
  2. ncbi Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohort
    Alexandra Nieters
    German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Eur J Nutr 41:210-21. 2002
    ....
  3. ncbi Cancer mortality in a cohort of male German iron foundry workers
    Karl Heinrich Adzersen
    German Cancer Research Center DKFZ, Division of Clinical Epidemiology, Heidelberg, Germany
    Am J Ind Med 43:295-305. 2003
    ..The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer...
  4. ncbi [Epidemiology of colorectal cancer]
    N Becker
    Abteilung Klinische Epidemiologie, Deutsches Krebsforschungszentrum, Heidelberg
    Radiologe 43:98-104. 2003
    ..Consistent encouragement of these possibilities for prevention could reduce incidence and mortality substantially and render colorectal tumors less frequent...
  5. ncbi [Experiences in scientific use of data from cancer registries]
    N Becker
    Deutsches Krebsforschungszentrum, Heidelberg
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 47:444-50. 2004
    ..Efforts must now focus on (a) achieving completeness, e. g., by making the reporting system more efficient and (b) harmonizing the legal regulations on cancer registration among the federal states and fitting them to practice...
  6. doi [Active monitoring of cancer clusters: comments from an epidemiological perspective]
    N Becker
    Epidemiologisches Krebsregister Baden Württemberg, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 581, 69120, Heidelberg, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 57:41-6. 2014
    ..Collaboration with professional cancer registries is advised. ..
  7. doi Hepatitis B virus infection is associated with deletion of chromosome 8p in multiple myeloma
    Nikolaus Becker
    Clinical Cancer Registry, National Center of Tumor Diseases and German Cancer Research Center, Im Neuenheimer Feld 581, Heidelberg, Germany
    Eur J Haematol 90:279-85. 2013
    ..36-5.50, P = 0.0048) and for loss of 13q14 non-significantly increased (OR = 1.40, 95% CL = 0.74-2.65) in anti-HBc positive patients. The results provide further support for a role of HBV infection in the pathogenesis of MM...
  8. doi Hepatitis B virus infection and risk of lymphoma: results of a serological analysis within the European case-control study Epilymph
    Nikolaus Becker
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany
    J Cancer Res Clin Oncol 138:1993-2001. 2012
    ....
  9. doi Randomized study on early detection of lung cancer with MSCT in Germany: study design and results of the first screening round
    N Becker
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany
    J Cancer Res Clin Oncol 138:1475-86. 2012
    ..Scope of the present study is to examine within a common European effort whether MSCT screening is capable to reduce the lung cancer mortality by at least 20 % and at which amount of undesired side effects this could be achieved...
  10. ncbi Evaluation of effectiveness of quality-assured mammography screening in Germany: sample size considerations and design options
    Nikolaus Becker
    German Cancer Research Center, Division of Cancer Epidemiology, Heidelberg, Germany
    Eur J Cancer Prev 16:225-31. 2007
    ..It is from this the individual truly benefits...
  11. ncbi Single nucleotide polymorphism--disease relationships: statistical issues for the performance of association studies
    Nikolaus Becker
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, Heidelberg 69120, Germany
    Mutat Res 525:11-8. 2003
    ..Additionally, minimal information is proposed which should be presented in publications about association studies in order to facilitate reproducibility studies by other authors...
  12. doi Epidemiology of multiple myeloma
    Nikolaus Becker
    German Cancer Research Center, Im Neuenheimer Feld 581, D 69120, Heidelberg, Germany
    Recent Results Cancer Res 183:25-35. 2011
    ..Finally, infections with HIV and hepatitis C virus appear related to an elevated multiple myeloma risk. Currently, large efforts are undertaken to unravel the etiology of malignant lymphoma including those of multiple myeloma...
  13. ncbi Birth order, allergies and lymphoma risk: results of the European collaborative research project Epilymph
    Nikolaus Becker
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Leuk Res 31:1365-72. 2007
    ..Our findings on birth order and lymphoma increase the inconsistency of findings across studies and suggest a critical reappraisal of potential underlying mechanisms...
  14. ncbi Epidemiological aspects of cancer screening in Germany
    Nikolaus Becker
    Deutsches Krebsforschungszentrum, Abteilung Klinische Epidemiologie, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    J Cancer Res Clin Oncol 129:691-702. 2003
    ..Based on these figures and present knowledge on the efficacy of screening modalities, we assessed past benefits and the future potential of cancer screening in Germany...
  15. ncbi Medical history and risk of lymphoma: results of a European case-control study (EPILYMPH)
    Nikolaus Becker
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
    J Cancer Res Clin Oncol 135:1099-107. 2009
    ..Lymphomas are a heterogeneous group of immune-cell malignancies. Immunology-related conditions are among the few factors for which consistent evidence exists relating them to lymphoma risk...
  16. ncbi Medical history and risk for lymphoma: results of a population-based case-control study in Germany
    Nikolaus Becker
    German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Eur J Cancer 41:133-42. 2005
    ..These results are compatible with the notion that persistent immunological alterations contribute to the aetiology of lymphoma, but partially inconsistent with the Th1/Th2-shift paradigm...
  17. ncbi Report on trends of incidence (1970-2002) of and mortality (1952-2002) from cancer in Germany
    Nikolaus Becker
    German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    J Cancer Res Clin Oncol 133:23-35. 2007
    ..It addresses also the issue of a cross-over of cancer mortality and mortality from cardiovascular diseases (CVD) in the near future, as suggested by various authors...
  18. doi Mortality among Thorotrast-exposed patients and an unexposed comparison group in the German Thorotrast study
    Nikolaus Becker
    Deutsches Krebsforschungszentrum, Abteilung Klin Epidemiologie, Im Neuenheimer Feld 280, Heidelberg, Germany
    Eur J Cancer 44:1259-68. 2008
    ..Mortality (total and selected cause-specific) increased with cumulative time since first exposure...
  19. ncbi [The role of epidemiological quality parameters in a mammography screening programme]
    N Becker
    Abteilung Klinische Epidemiologie, Deutsches Krebsforschungszentrum Heidelberg, Im Neuenheimer Feld 280, 69120 Heidelberg
    Radiologe 46:984-92. 2006
    ..The reasons for focussing on those parameters, on which the European Guidelines and now the German programme are based, and their significance in the long-term effectiveness of this programme are explained...
  20. ncbi [Screening from an epidemiologic perspective]
    N Becker
    Abteilung Krebsepidemiologie, Deutsches Krebsforschungszentrum, Heidelberg, Deutschland
    Radiologe 48:10, 12-6. 2008
    ..The present article provides an overview of the basic obstacles and how to cope with them. It turns out that quality assurance of service screening has to be considered not as optional but as a condition sine qua non...
  21. doi [Epidemiology of prostate cancer]
    N Becker
    Abteilung Epidemiologie von Krebserkrankungen, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 581, 69120, Heidelberg, Deutschland
    Radiologe 51:922-9. 2011
    ..Before routine application the novel approaches also have to be scrutinized in a research setting...
  22. ncbi Cancer mortality in the United States and Germany
    N Becker
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    J Cancer Res Clin Oncol 127:293-300. 2001
    ..If it is true that the major part of cancer occurrence is lifestyle-related, we should see corresponding discrepancies and assimilations on the level of cancer occurrence...
  23. ncbi The fibroblast growth factor receptor gene Arg388 allele is not associated with early lymph node metastasis of breast cancer
    Nikolaus Becker
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, 69120 Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 12:582-3. 2003
  24. ncbi Association of polymorphisms in Th1, Th2 cytokine genes with hayfever and atopy in a subsample of EPIC-Heidelberg
    A Nieters
    Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Clin Exp Allergy 34:346-53. 2004
    ..Indications exist that polymorphisms in cytokine genes involved in the regulation of the Th1/Th2 balance may contribute to the allergic phenotype...
  25. ncbi Cooking of meat and fish in Europe--results from the European Prospective Investigation into Cancer and Nutrition (EPIC)
    S Rohrmann
    Division of Clinical Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Eur J Clin Nutr 56:1216-30. 2002
    ..Since data on food cooking methods are scarce, the aim of this study was to describe the variation in meat and fish cooking methods in different parts of Europe...
  26. ncbi Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk
    A Nieters
    Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Genes Immun 7:615-24. 2006
    ..76, 95% CI=1.12-6.81) and HL (OR=1.80, 95% CI=0.99-3.26). In conclusion, this study suggests an effect of polymorphisms in factors of the innate immune response in the aetiology of some lymphoma subtypes...
  27. ncbi [Screening from the epidemiological viewpoint]
    N Becker
    Abteilung Klinische Epidemiologie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg
    Radiologe 42:592-600. 2002
    ....
  28. ncbi [The use of the Epidemiology Cancer registry Baden-Württemberg in the follow-up of the EPIC cohort]
    G Nagel
    Abteilung Klinische Epidemiologie, Deutsches Krebsforschungszentrum, Heidelberg
    Gesundheitswesen 66:469-74. 2004
    ..Since the technical requirements are complied with, attempts should be made to improve the completeness of the epidemiological cancer registry Baden- Württemberg...
  29. ncbi Time trends in cigarette smoking in two German cohorts--results from EPIC Germany
    S Rohrmann
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Eur J Cancer Prev 12:327-32. 2003
    ..However, they did differ according to the quantity and quality of smoking. These differences, as well as the changes over the last 40 years may contribute to a changing pattern of diseases in different groups of the German population...
  30. ncbi Patterns of past alcohol consumption in the EPIC-Germany cohorts. European Investigation into Cancer and Nutrition
    K Klipstein-Grobusch
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbrucke, Heidelberg, Germany
    Ann Nutr Metab 43:258-65. 1999
    ..The data indicate that collection of alcohol consumption data at various discrete points in time is essential to depict life-long history of alcohol consumption...
  31. ncbi EPIC-Germany--A source for studies into diet and risk of chronic diseases. European Investigation into Cancer and Nutrition
    H Boeing
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbrucke, Heidelberg, Germany
    Ann Nutr Metab 43:195-204. 1999
    ..These studies will be conducted on cancer at the international level and on non-cancer diseases at the national or local level...
  32. ncbi Joint effect between regular use of non-steroidal anti-inflammatory drugs, variants in inflammatory genes and risk of lymphoma
    Birgit Hoeft
    Molecular Tumour Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, Germany
    Cancer Causes Control 19:163-73. 2008
    ..To further research in this area, we investigated the role of genetic variants in key inflammatory factors, non-steroidal anti-inflammatory drug [NSAID] use, and their joint effect in lymphomagenesis...
  33. ncbi SMR analysis of historical follow-up studies with missing death certificates
    W Rittgen
    Department of Biostatistics, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Biometrics 56:1164-9. 2000
    ..Easily computable confidence limits can be obtained by dividing the usual confidence limits of the SMR by the opposite limit of the proportion p. However, the confidence level alpha has to be adjusted appropriately...
  34. doi [Epidemiology of lung cancer]
    N Becker
    Abteilung Krebsepidemiologie, Deutsches Krebsforschungszentrum Heidelberg, Im Neuenheimer Feld 581, 69120, Heidelberg, Deutschland
    Radiologe 50:654-61. 2010
    ..The results are not expected for some years. Until then the early detection of lung cancer with MSCT cannot be considered suitable for routine use but can only be justified within the framework of research studies...
  35. ncbi Epidemiologic aspects of cancer prevention in Germany
    N Becker
    German Cancer Research Center, Division of Clinical Epidemiology, Heidelberg
    J Cancer Res Clin Oncol 127:9-19. 2001
    ..The estimates are based on very conservative assumptions. They yield, for the theoretical potential, values in the range 43-65% and for the reduction actually obtainable in the medium term due to primary prevention, values of 18-31%...
  36. ncbi Influence of dietary fatty acid, vegetable, and vitamin intake on etheno-DNA adducts in white blood cells of healthy female volunteers: a pilot study
    T Hagenlocher
    Division of Toxicology, German Cancer Research Center (Deutsches Krebsforschungszentrum, 69120 Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 10:1187-91. 2001
    ..This pilot study also indicated a protective effect of dietary vitamin E and vegetables against miscoding, lipid peroxidation-induced DNA lesions...
  37. ncbi The influence of the dietary intake of fatty acids and antioxidants on hay fever in adults
    G Nagel
    Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Allergy 58:1277-84. 2003
    ..The objective of the investigation was to explore in a prospective study the associations between dietary intake of fatty acids, antioxidants and hay fever manifestation in adulthood...
  38. ncbi Asbestos exposure and malignant lymphomas--a review of the epidemiological literature
    N Becker
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Int Arch Occup Environ Health 74:459-69. 2001
    ..Such studies should address separately the various sub-entities, employing the latest internationally agreed classification, and should also use the latest methods of quantifying exposure...
  39. ncbi Trends in cigarette smoking in the German centers of the European Prospective Investigation into Cancer and Nutrition (EPIC): the influence of the educational level
    Sabine Rohrmann
    German Cancer Research Center, Division of Clinical Epidemiology, Heidelberg, Germany
    Prev Med 36:448-54. 2003
    ....
  40. ncbi Fruit and vegetable consumption and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Sabine Rohrmann
    Division of Clinical Epidemiology C020, German Cancer Research Centre, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany
    Cancer Causes Control 18:537-49. 2007
    ..The best-established risk factors are related to dys-regulation of immune function, and evidence suggests that factors such as dietary or lifestyle habits may be involved in the etiology...
  41. doi Smoking and lymphoma risk in the European prospective investigation into cancer and nutrition
    Alexandra Nieters
    Division of Cancer Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
    Am J Epidemiol 167:1081-9. 2008
    ..Future analysis should involve viral biomarkers and genetic susceptibility markers to elucidate potential mechanisms of smoking-induced carcinogenesis, particularly for Hodgkin's lymphoma...
  42. ncbi Hepatitis C and risk of lymphoma: results of the European multicenter case-control study EPILYMPH
    Alexandra Nieters
    German Cancer Research Center, Heidelberg, Germany
    Gastroenterology 131:1879-86. 2006
    ..However, previous epidemiologic studies were limited in size to establish an association between HCV infection and specific lymphoma subtypes. We performed a large, multicenter, case-control study to address this question...
  43. ncbi Tobacco and alcohol consumption and risk of lymphoma: results of a population-based case-control study in Germany
    Alexandra Nieters
    Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Int J Cancer 118:422-30. 2006
    ..In conclusion, this investigation suggests a positive association between tobacco smoking and lymphoma risk and finds decreased odds ratios among consumers of alcohol...
  44. ncbi Cross-sectional study on cytokine polymorphisms, cytokine production after T-cell stimulation and clinical parameters in a random sample of a German population
    A Nieters
    Deutsches Krebsforschungszentrum, Abteilung Klinische Epidemiologie, Heidelberg, Germany
    Hum Genet 108:241-8. 2001
    ..If confirmed, these relationships could contribute to a better characterisation of the genetic component of allergies...
  45. ncbi Lifestyle and diet in people using dietary supplements: a German cohort study
    Annika Reinert
    Division of Cancer Epidemiology, German Cancer Research Centre, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Eur J Nutr 46:165-73. 2007
    ..The use of dietary supplements is often associated with a healthy lifestyle. Due to high variation in supplementation practice by country, these associations will be investigated in a large German cohort study...
  46. ncbi Linear regression calibration: theoretical framework and empirical results in EPIC, Germany
    Gisela Kynast-Wolf
    Division of Clinical Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Ann Nutr Metab 46:2-8. 2002
    ..We conclude that calibration is a necessary step in multicenter studies. However, this exercise shows that the current statistical framework is not yet sufficiently developed for a broad application...
  47. ncbi Socio-demographic characteristics of participation in the opportunistic German cervical cancer screening programme: results from the EPIC-Heidelberg cohort
    David Seidel
    Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120, Heidelberg, Germany
    J Cancer Res Clin Oncol 135:533-41. 2009
    ..To analyse participation in the German cervical cancer screening programme by socio-demographic characteristics...
  48. ncbi Population-based study of lymphoma in Germany: rationale, study design and first results
    Nikolaus Becker
    Deutsches Krebsforschungszentrum, Abteilung Klinische Epidemiologie, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Leuk Res 28:713-24. 2004
    ..The inconsistencies of some of the findings with an explanation by the Th1/Th2 paradigm, however, warrant further research and may indicate that broader explanatory concepts are needed...
  49. ncbi Randomized trial with fruits and vegetables in prevention of cancer
    Keyvan Tadjalli-Mehr
    German Cancer Research Centre, Division of Clinical Epidemiology, Heidelberg, Germany
    Acta Oncol 42:287-93. 2003
    ..For a comparably short period the Baltic countries offer a time-window for a randomized trial. It is unlikely that the costs of such a trial would considerably exceed the costs of the available chemoprevention trials...
  50. ncbi Use of high-temperature cooking methods in preparation of meat and fish in European countries
    S Rohrmann
    Deutsches Krebsforschungszentrum, Heidelberg, Germany
    IARC Sci Publ 156:219-20. 2002
  51. ncbi [Computed tomography screening for lung cancer]
    N Becker
    Abteilung Krebsepidemiologie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 581, 69120, Heidelberg, Deutschland
    Radiologe 53:757-63. 2013
    ..Before the final analysis in several years time routine lung cancer screening with MSCT cannot be recommended and MSCT lung screening can only be performed within the framework of studies. ..
  52. doi Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro
    L M Dittmann
    Division of Molecular Genetics, German Cancer Research Center, Heidelberg, Germany
    Oncogene 31:3409-18. 2012
    ..Taken together, our findings indicate that epigenetic silencing of PRDX1 is frequent in 1p/19q-deleted oligodendroglial tumours and likely contributes to radio- and chemosensitivity of these tumours...
  53. pmc Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples
    Janne Pullat
    Division of Functional Genome Analysis, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
    BMC Genomics 8:282. 2007
    ....
  54. ncbi Development of a short questionnaire to assess the dietary intake of heterocyclic aromatic amines
    Sabine Rohrmann
    Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Public Health Nutr 5:699-705. 2002
    ..Development and validation of a short instrument to assess the dietary intake of heterocyclic aromatic amines (HCA)...
  55. ncbi Personal use of hair dye and the risk of certain subtypes of non-Hodgkin lymphoma
    Yawei Zhang
    Environmental Science Division, School of Public Health, Yale University, New Haven, CT, USA
    Am J Epidemiol 167:1321-31. 2008
    ..1, 2.0). These results indicate that personal hair-dye use may play a role in risks of FL and CLL/SLL in women who started use before 1980 and that increased risk of FL among women who started use during or after 1980 cannot be excluded...
  56. doi Diabetes and the risk of non-Hodgkin's lymphoma and multiple myeloma in the European Prospective Investigation into Cancer and Nutrition
    Aneire E Khan
    Department of Epidemiology and Public Health, Division of Epidemiology, Public Health and Primary Care, Imperial College London, St Mary s Campus, Variety Wing, Norfolk Place, Paddington, London W2 1PG
    Haematologica 93:842-50. 2008
    ..Increases in the incidence of non-Hodgkin's lymphoma and multiple myeloma in the past implicate environmental factors as potential causal agents...
  57. doi Exposure to ultraviolet radiation and risk of malignant lymphoma and multiple myeloma--a multicentre European case-control study
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Int J Epidemiol 37:1080-94. 2008
    ..Three recent studies have reported a decreased risk of non-Hodgkin lymphoma (NHL) for high ultraviolet (UV) radiation exposure...
  58. pmc Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma
    Christine F Skibola
    School of Public Health, Division of Environmental Health Sciences, University of California Berkeley, Berkeley, California, USA
    PLoS ONE 3:e2816. 2008
    ..Non-Hodgkin lymphoma (NHL) is the fifth most common cancer in the U.S. and few causes have been identified. Genetic association studies may help identify environmental risk factors and enhance our understanding of disease mechanisms...
  59. doi Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Julie A Britton
    Department of Epidemiology and Public Health, Imperial College London, Room 151, St Mary s Campus, Norfolk Place W2 1PG, London, UK
    Haematologica 93:1666-77. 2008
    ..It has been hypothesized that this may be due, in part, to the parallel rising prevalence of obesity. It is biologically plausible that anthropometric characteristics can infuence the risk of non-Hodgkin's lymphoma and multiple myeloma...
  60. ncbi Epstein-Barr virus infection and risk of lymphoma: immunoblot analysis of antibody responses against EBV-related proteins in a large series of lymphoma subjects and matched controls
    Silvia de Sanjose
    Servei d Epidemiologia and Registre del Cancer, IDIBELL, Institut Catala d Oncologia, Gran Via Km 2 7, 08907 L Hospitalet, Barcelona, Spain
    Int J Cancer 121:1806-12. 2007
    ..Ab_EBV is a useful tool to explore EBV imbalances preceding or paralleling possible EBV associated oncogenic events...
  61. pmc Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph)
    Sophia S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Blood 109:3479-88. 2007
    ..0; 95% CI = 1.6-5.6). The pattern of NHL heritability appeared to be uniform across NHL subtypes, but risk patterns differed by specific hematopoietic malignancies and the sex of the relative, revealing critical clues to disease etiology...
  62. ncbi Disease mapping of stage-specific cancer incidence data
    Leonhard Knorr-Held
    Department of Mathematics and Statistics, Lancaster University, UK
    Biometrics 58:492-501. 2002
    ..The results suggest that there are large spatial differences in the stage proportions, which indicate spatial variability with respect to the introduction and effectiveness of Pap smear screening programs...
  63. ncbi Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Germany
    Int J Cancer 118:728-38. 2006
    ..Our data give further credence to public health efforts aiming to reduce the prevalence of obesity to prevent RCC, in addition to other chronic diseases...
  64. ncbi Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology Consortium
    Silvia de Sanjose
    Unit of Infections and Cancer, Catalan Institute of Oncology, Institut d Investigacio Biomedica de Bellvitge, Centro de Investigación Biomédica en Red Epidemiología y Salud Pública, Barcelona, Spain
    Clin Gastroenterol Hepatol 6:451-8. 2008
    ..We pooled case-control study data to provide robust estimates of the risk of non-Hodgkin's lymphoma (NHL) subtypes after HCV infection...
  65. ncbi Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium
    Nathaniel Rothman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Lancet Oncol 7:27-38. 2006
    ..We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph)...
  66. ncbi Sun exposure and malignant lymphoma: a population-based case-control study in Germany
    Thomas Weihkopf
    Institute of Medical Biostatistics, Epidemiology and Informatics, Johannes Gutenberg University, Mainz, Germany
    Int J Cancer 120:2445-51. 2007
    ..This data suggest that exposure to natural and artificial ultraviolet radiation may reduce the OR for lymphoma in this study population...
  67. ncbi Influence of familial cancer history on lymphoid neoplasms risk validated in the large European case-control study epilymph
    Romain Casey
    Registre des Hémopathies Malignes de Côte d Or, EA INSERM InVs 4T0003C, faculté de médecine de Dijon, 7 Boulevard Jeanne d Arc, 21 000 Dijon, France
    Eur J Cancer 42:2570-6. 2006
    ..Our study suggests familial aggregation of CLL with a family history of haematological cancer and of HL with a family history of lymphoma. The transmission pattern suggests a dominant model of heredity...
  68. ncbi Body size and risk of colon and rectal cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC)
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition DIfE, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    J Natl Cancer Inst 98:920-31. 2006
    ..This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women...
  69. ncbi Association between personal use of hair dyes and lymphoid neoplasms in Europe
    Silvia de Sanjose
    Catalan Institute of Oncology, Barcelona, Spain
    Am J Epidemiol 164:47-55. 2006
    ..10, 2.40). Personal use of hair dyes is associated with a moderate increase in lymphoma risk, particularly among women and persons who used dyes before 1980. Specific compounds associated with this risk remain to be elucidated...
  70. ncbi Retrospective quantification of background incidence and stage distribution of breast cancer for the mammography screening pilot project in Wiesbaden, Germany
    Gisela Schott
    Pilot Project Mammography Screening Wiesbaden, Michelsberg 3, 65183 Wiesbaden, Germany
    J Cancer Res Clin Oncol 134:29-35. 2008
    ..This incidence rate is 2.5 per 1,000, while that found in the Wiesbaden area was 2.7 per 1,000...
  71. ncbi Occupational exposure to meat and risk of lymphoma: a multicenter case-control study from Europe
    Tina Moore
    Department of Lifestyle, Environment and Cancer, International Agency for Research on Cancer, Lyon, France
    Int J Cancer 121:2761-6. 2007
    ..Occupational exposure to meat does not appear to represent an important risk factor of lymphoma, although an increased risk of specific types of non-Hodgkin lymphoma cannot be excluded...
  72. ncbi Personal sun exposure and risk of non Hodgkin lymphoma: a pooled analysis from the Interlymph Consortium
    Anne Kricker
    School of Public Health, University of Sydney, Sydney, New South Wales, Australia
    Int J Cancer 122:144-54. 2008
    ..Increased recreational sun exposure may protect against NHL...
  73. ncbi Variation in DNA repair genes XRCC3, XRCC4, XRCC5 and susceptibility to myeloma
    Patrick J Hayden
    Durkan Leukaemia Laboratories, Department of Haematology, Institute of Molecular Medicine, Trinity College Dublin, Ireland
    Hum Mol Genet 16:3117-27. 2007
    ..015). This SNP is located in the 3'-UTR of XRCC5. Overall, these data provide support for the hypothesis that common variation in the genes encoding DNA repair proteins contributes to susceptibility to myeloma...
  74. ncbi Tobacco smoking, alcohol drinking and non-Hodgkin's lymphoma: A European multicenter case-control study (Epilymph)
    Herve Besson
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 119:901-8. 2006
    ..The results of this large-scale European study did not support an association between tobacco and NHL and suggested a protective effect of alcohol on development of NHL for men and in non-Mediterranean countries...
  75. ncbi Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition
    Steffen Weikert
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal, Germany
    Am J Epidemiol 167:438-46. 2008
    ..These results support the hypothesis that hypertension, rather than its medications, increases the risk of RCC in both sexes, while effective blood pressure control may lower the risk...
  76. ncbi Non-Hodgkin lymphoma and obesity: a pooled analysis from the InterLymph Consortium
    Eleanor V Willett
    Epidemiology and Genetics Unit, Department of Health Sciences, University of York, Heslington, York YO10 5DD, United Kingdom
    Int J Cancer 122:2062-70. 2008
    ....
  77. ncbi Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC)
    Steffen Weikert
    Department of Epidemiology, German Institute of Human Nutrition Potsdam Rehbruecke, Nuthetal
    Int J Cancer 118:3133-9. 2006
    ..The relationship of specific fruit and vegetable subgroups with RCC risk warrant further investigation...
  78. pmc A functional TNFRSF5 gene variant is associated with risk of lymphoma
    Christine F Skibola
    Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    Blood 111:4348-54. 2008
    ..These results suggest that the TNFRSF5 -1C>T polymorphism may increase FL susceptibility through mechanisms that hinder cellular immune responses. Further studies are needed to explore these findings...
  79. pmc Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium
    Karin Ekstrom Smedby
    Department of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
    Blood 111:4029-38. 2008
    ..Thus, specific autoimmune disorders are associated with NHL risk beyond the development of rare NHL subtypes in affected organs. The pattern of associations with NHL subtypes may harbor clues to lymphomagenesis...
  80. ncbi Statin use and risk of lymphoid neoplasms: results from the European Case-Control Study EPILYMPH
    Joan Fortuny
    Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Gran Via Km 2 7, 08907 L Hospitalet de Llobregat, Autonomous University of Barcelona corrected Barcelona, Catalonia, Spain
    Cancer Epidemiol Biomarkers Prev 15:921-5. 2006
    ..Statins, drugs used to treat dyslipidemia, may have anticancer properties. We have evaluated lymphoma risk associated with regular statin use in an international case-control study...
  81. ncbi Towards joint disease mapping
    Leonhard Held
    Department of Statistics, University of Munich, Germany
    Stat Methods Med Res 14:61-82. 2005
    ....