Stephanie Bechtel

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. ncbi request reprint An anthropoid-specific segmental duplication on human chromosome 1q22
    Vladimir Yu Kuryshev
    Department of Molecular Genome Analysis, DKFZ German Cancer Research Center, INF 580, D 69120 Heidelberg, Germany
    Genomics 88:143-51. 2006
  2. pmc Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration
    Siau Wei Baï
    Randall Division of Cell and Molecular Biophysics, King s College London, New Hunt s House, Guy s Campus, London SE11UL, UK
    BMC Biol 9:54. 2011
  3. pmc The full-ORF clone resource of the German cDNA Consortium
    Stephanie Bechtel
    Department of Molecular Genome Analysis, German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Genomics 8:399. 2007
  4. ncbi request reprint High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins
    Mamatha Sauermann
    Division of Molecular Genome Analysis, German Cancer Research Centre, Heidelberg, Germany
    J Biomol Screen 12:510-20. 2007
  5. pmc Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation
    Jitao David Zhang
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    PLoS ONE 6:e22176. 2011
  6. ncbi request reprint Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle
    Dorit Arlt
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Cancer Res 65:7733-42. 2005
  7. ncbi request reprint Large-scale protein expression for proteome research
    Ulrike Korf
    Molecular Genome Analysis, DKFZ, Heidelberg, Germany
    Proteomics 5:3571-80. 2005
  8. ncbi request reprint The German cDNA network: cDNAs, functional genomics and proteomics
    Stefan Wiemann
    Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    J Struct Funct Genomics 4:87-96. 2003
  9. pmc The LIFEdb database in 2006
    Alexander Mehrle
    Division Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Nucleic Acids Res 34:D415-8. 2006
  10. pmc From ORFeome to biology: a functional genomics pipeline
    Stefan Wiemann
    Molecular Genome Analysis, German Cancer Research Center, 69120 Heidelberg, Germany
    Genome Res 14:2136-44. 2004

Collaborators

Detail Information

Publications12

  1. ncbi request reprint An anthropoid-specific segmental duplication on human chromosome 1q22
    Vladimir Yu Kuryshev
    Department of Molecular Genome Analysis, DKFZ German Cancer Research Center, INF 580, D 69120 Heidelberg, Germany
    Genomics 88:143-51. 2006
    ..Moreover, we provide detailed information regarding structure and evolution of the SD1q22 region that is a prerequisite for future studies of its anthropoid-specific functions and possible linkage to human genetic disorders...
  2. pmc Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration
    Siau Wei Baï
    Randall Division of Cell and Molecular Biophysics, King s College London, New Hunt s House, Guy s Campus, London SE11UL, UK
    BMC Biol 9:54. 2011
    ..Cell migration is essential during development and in human disease progression including cancer. Most cell migration studies concentrate on known or predicted components of migration pathways...
  3. pmc The full-ORF clone resource of the German cDNA Consortium
    Stephanie Bechtel
    Department of Molecular Genome Analysis, German Cancer Research Center DKFZ, Heidelberg, Germany
    BMC Genomics 8:399. 2007
    ..In combination with a unique and versatile cloning system, these will provide the tools for genome-wide systematic functional analyses, to achieve a deeper insight into complex biological processes...
  4. ncbi request reprint High-throughput flow cytometry-based assay to identify apoptosis-inducing proteins
    Mamatha Sauermann
    Division of Molecular Genome Analysis, German Cancer Research Centre, Heidelberg, Germany
    J Biomol Screen 12:510-20. 2007
    ..The candidate proteins were all verified in an independent microscopy-based nuclear fragmentation assay, finally resulting in the identification of 6 apoptosis inducers...
  5. pmc Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation
    Jitao David Zhang
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    PLoS ONE 6:e22176. 2011
    ..Our work establishes RTCA technology as a novel robust tool with biological and pharmacological relevance amenable for high-throughput screening...
  6. ncbi request reprint Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle
    Dorit Arlt
    Division of Molecular Genome Analysis, German Cancer Research Center, Heidelberg, Germany
    Cancer Res 65:7733-42. 2005
    ..We have established a novel functional profiling strategy that links genomics to cell biology and showed its potential for discerning cancer relevant modulators of the cell cycle in the candidate lists from microarray studies...
  7. ncbi request reprint Large-scale protein expression for proteome research
    Ulrike Korf
    Molecular Genome Analysis, DKFZ, Heidelberg, Germany
    Proteomics 5:3571-80. 2005
    ..Affinity-purified fusion proteins were confirmed by MALDI-TOF MS...
  8. ncbi request reprint The German cDNA network: cDNAs, functional genomics and proteomics
    Stefan Wiemann
    Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    J Struct Funct Genomics 4:87-96. 2003
    ....
  9. pmc The LIFEdb database in 2006
    Alexander Mehrle
    Division Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Nucleic Acids Res 34:D415-8. 2006
    ..LIFEdb enables researchers to systematically select and characterize genes and proteins of interest, and presents data and information via its user-friendly web-based interface...
  10. pmc From ORFeome to biology: a functional genomics pipeline
    Stefan Wiemann
    Molecular Genome Analysis, German Cancer Research Center, 69120 Heidelberg, Germany
    Genome Res 14:2136-44. 2004
    ..All information is presented in a Web database (http://www.dkfz.de/LIFEdb). It is exploited for the identification of disease-relevant genes and proteins for diagnosis and therapy...
  11. ncbi request reprint CDNAs for functional genomics and proteomics: the German Consortium
    Stefan Wiemann
    Molecular Genome Analysis, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
    C R Biol 326:1003-9. 2003
    ..The resulting information is integrated with functional genomics and proteomics data for further understanding of protein functions in the cellular context...
  12. pmc The systematic functional characterisation of Xq28 genes prioritises candidate disease genes
    Anja Kolb-Kokocinski
    Division of Molecular Genome Analysis, German Cancer Research Centre DKFZ, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
    BMC Genomics 7:29. 2006
    ..To expedite disease gene identification, we have initiated the functional characterisation of all known Xq28 genes...