Christian P Bacher

Summary

Affiliation: German Cancer Research Center
Country: Germany

Publications

  1. pmc 4-D single particle tracking of synthetic and proteinaceous microspheres reveals preferential movement of nuclear particles along chromatin - poor tracks
    Christian P Bacher
    Division of Theoretical Bioinformatics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
    BMC Cell Biol 5:45. 2004
  2. pmc Nuclear body movement is determined by chromatin accessibility and dynamics
    Sabine M Görisch
    Division of Molecular Genetics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Proc Natl Acad Sci U S A 101:13221-6. 2004
  3. ncbi request reprint Trichostatin A-induced histone acetylation causes decondensation of interphase chromatin
    Katalin Fejes Toth
    Kirchhoff Institut für Physik, AG Molekulare Biophysik, Ruprecht Karls Universitat Heidelberg, Im Neuenheimer Feld 227, 69120 Heidelberg, Germany
    J Cell Sci 117:4277-87. 2004
  4. ncbi request reprint A contractile nuclear actin network drives chromosome congression in oocytes
    Peter Lenart
    Gene Expression and Cell Biology Biophysics Programmes, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Nature 436:812-8. 2005

Collaborators

  • Karsten Rippe
  • H Herrmann
  • MARK R TERASAKI
  • Peter Lenart
  • Malte Wachsmuth
  • Sabine M Görisch
  • Katalin Fejes Toth
  • Nathalie Daigle
  • Jan Ellenberg
  • Roland Eils
  • Arthur R Hand
  • Michael Stohr
  • Tobias A Knoch
  • Monika Frank-Stöhr
  • Gabriele Müller
  • Carina Ittrich
  • Peter Lichter

Detail Information

Publications4

  1. pmc 4-D single particle tracking of synthetic and proteinaceous microspheres reveals preferential movement of nuclear particles along chromatin - poor tracks
    Christian P Bacher
    Division of Theoretical Bioinformatics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany
    BMC Cell Biol 5:45. 2004
    ..Typically, such studies generate a wealth of data that require novel methods in image analysis and computational tools to quantitatively track particle movement on the background of moving cells and shape changing nuclei...
  2. pmc Nuclear body movement is determined by chromatin accessibility and dynamics
    Sabine M Görisch
    Division of Molecular Genetics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
    Proc Natl Acad Sci U S A 101:13221-6. 2004
    ..This finding suggests that the body mobility reflects the dynamics and accessibility of the chromatin environment, which might target bodies to specific nuclear subcompartments where they exert their biological function...
  3. ncbi request reprint Trichostatin A-induced histone acetylation causes decondensation of interphase chromatin
    Katalin Fejes Toth
    Kirchhoff Institut für Physik, AG Molekulare Biophysik, Ruprecht Karls Universitat Heidelberg, Im Neuenheimer Feld 227, 69120 Heidelberg, Germany
    J Cell Sci 117:4277-87. 2004
    ..An analysis by flow cytometry showed that the addition of TSA led to a significant arrest of cells in S phase and induced apoptosis. The concentration dependence of both processes was studied...
  4. ncbi request reprint A contractile nuclear actin network drives chromosome congression in oocytes
    Peter Lenart
    Gene Expression and Cell Biology Biophysics Programmes, European Molecular Biology Laboratory EMBL, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    Nature 436:812-8. 2005
    ..We show that this mechanism is essential for preventing chromosome loss and aneuploidy of the egg--a leading cause of pregnancy loss and birth defects in humans...