Manfred Gerlach

Summary

Country: Germany

Publications

  1. doi Is the treatment with psychostimulants in children and adolescents with attention deficit hyperactivity disorder harmful for the dopaminergic system?
    Manfred Gerlach
    Department for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    Atten Defic Hyperact Disord 5:71-81. 2013
  2. doi The effect of piribedil on L-DOPA-induced dyskinesias in a rat model of Parkinson's disease: differential role of α(2) adrenergic mechanisms
    Manfred Gerlach
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    J Neural Transm 120:31-6. 2013
  3. doi Neuromelanin-bound ferric iron as an experimental model of dopaminergic neurodegeneration in Parkinson's disease
    Manfred Gerlach
    University of Wurzburg, Department of Child and Adolescent Psychiatry and Psychotherapy, Laboratory for Clinical Neurobiology, Wurzburg, Germany
    Parkinsonism Relat Disord 14:S185-8. 2008
  4. doi Flibanserin attenuates L: -DOPA-sensitized contraversive circling in the unilaterally 6-hydroxydopamine-lesioned rat model of Parkinson's disease
    Manfred Gerlach
    Laboratory for Clinical Neurobiology, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    J Neural Transm 118:1727-32. 2011
  5. pmc Drug monitoring in child and adolescent psychiatry for improved efficacy and safety of psychopharmacotherapy
    Claudia Mehler Wex
    TDM Laboratory, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Fuechsleinstr 5, 97080 Wuerzburg, Germany
    Child Adolesc Psychiatry Ment Health 3:14. 2009
  6. doi Role of dopamine D3 and serotonin 5-HT 1A receptors in L: -DOPA-induced dyskinesias and effects of sarizotan in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease
    Manfred Gerlach
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Laboratory for Clinical Neurobiology, University of Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    J Neural Transm 118:1733-42. 2011
  7. pmc Biomarker candidates of neurodegeneration in Parkinson's disease for the evaluation of disease-modifying therapeutics
    Manfred Gerlach
    Department for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
    J Neural Transm 119:39-52. 2012
  8. doi Reduced thermal hyperalgesia and enhanced peripheral nerve injury after hind paw inflammation in mice lacking the serotonin-transporter
    Florian Palm
    Department of Neurology, University of Wurzburg, Neurologische Klinik der Universität, D 97080 Wurzburg, Germany
    Eur J Pain 12:790-7. 2008
  9. doi Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder
    Regina Taurines
    Hospital of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    World J Biol Psychiatry 12:104-8. 2011
  10. doi No elevated genomic damage in children and adolescents with attention deficit/hyperactivity disorder after methylphenidate therapy
    Susanne Walitza
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Fuechsleinstr 15, 97080 Wuerzburg, Germany
    Toxicol Lett 184:38-43. 2009

Detail Information

Publications52

  1. doi Is the treatment with psychostimulants in children and adolescents with attention deficit hyperactivity disorder harmful for the dopaminergic system?
    Manfred Gerlach
    Department for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    Atten Defic Hyperact Disord 5:71-81. 2013
    ....
  2. doi The effect of piribedil on L-DOPA-induced dyskinesias in a rat model of Parkinson's disease: differential role of α(2) adrenergic mechanisms
    Manfred Gerlach
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    J Neural Transm 120:31-6. 2013
    ..Clonidine blocked the effect of piribedil on AD, OD and FD. These data suggest a differential involvement of α(2) adrenergic receptors in the action of piribedil on different subclasses of L-DOPA-induced dyskinesias...
  3. doi Neuromelanin-bound ferric iron as an experimental model of dopaminergic neurodegeneration in Parkinson's disease
    Manfred Gerlach
    University of Wurzburg, Department of Child and Adolescent Psychiatry and Psychotherapy, Laboratory for Clinical Neurobiology, Wurzburg, Germany
    Parkinsonism Relat Disord 14:S185-8. 2008
    ....
  4. doi Flibanserin attenuates L: -DOPA-sensitized contraversive circling in the unilaterally 6-hydroxydopamine-lesioned rat model of Parkinson's disease
    Manfred Gerlach
    Laboratory for Clinical Neurobiology, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    J Neural Transm 118:1727-32. 2011
    ..The current preclinical findings further implicate the 5-HT(1A) receptor as a promising therapeutic target for the reduction of LID and predict a potential efficacy of flibanserin in the treatment of LID in PD...
  5. pmc Drug monitoring in child and adolescent psychiatry for improved efficacy and safety of psychopharmacotherapy
    Claudia Mehler Wex
    TDM Laboratory, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Fuechsleinstr 5, 97080 Wuerzburg, Germany
    Child Adolesc Psychiatry Ment Health 3:14. 2009
    ....
  6. doi Role of dopamine D3 and serotonin 5-HT 1A receptors in L: -DOPA-induced dyskinesias and effects of sarizotan in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease
    Manfred Gerlach
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Laboratory for Clinical Neurobiology, University of Wurzburg, Fuchsleinstrasse 15, 97080, Wurzburg, Germany
    J Neural Transm 118:1733-42. 2011
    ..This selective involvement is in contrast to the more general involvement of 5-HT(1A) receptors in the anti-dyskinetic effects of sarizotan...
  7. pmc Biomarker candidates of neurodegeneration in Parkinson's disease for the evaluation of disease-modifying therapeutics
    Manfred Gerlach
    Department for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
    J Neural Transm 119:39-52. 2012
    ..Almost all of the biomarker candidates were not investigated in relation to effects of treatment, validated in experimental models of PD and confirmed in independent studies...
  8. doi Reduced thermal hyperalgesia and enhanced peripheral nerve injury after hind paw inflammation in mice lacking the serotonin-transporter
    Florian Palm
    Department of Neurology, University of Wurzburg, Neurologische Klinik der Universität, D 97080 Wurzburg, Germany
    Eur J Pain 12:790-7. 2008
    ..Human variants of the 5-HTT genotypes might be part of the factors determining the extent of nerve injury and hyperalgesia in inflammation...
  9. doi Altered mRNA expression of monoaminergic candidate genes in the blood of children with attention deficit hyperactivity disorder and autism spectrum disorder
    Regina Taurines
    Hospital of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    World J Biol Psychiatry 12:104-8. 2011
    ....
  10. doi No elevated genomic damage in children and adolescents with attention deficit/hyperactivity disorder after methylphenidate therapy
    Susanne Walitza
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Fuechsleinstr 15, 97080 Wuerzburg, Germany
    Toxicol Lett 184:38-43. 2009
    ..Furthermore, micronuclei were analyzed in a second tissue, buccal mucosa...
  11. ncbi Oxidative stress in the brain at early preclinical stages of mouse scrapie
    Seong Wook Yun
    Clinical Neurochemistry and NPF Center of Excellence Research Laboratories, Clinic of Psychiatry and Psychotherapy, University of Wurzburg, 97080 Wurzburg, Germany
    Exp Neurol 201:90-8. 2006
    ....
  12. doi Effects of methylphenidate on olfaction and frontal and temporal brain oxygenation in children with ADHD
    Martin Schecklmann
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Germany
    J Psychiatr Res 45:1463-70. 2011
    ....
  13. doi Effects of methylphenidate: the cellular point of view
    Jasmin Bartl
    Clinical Neurochemistry Laboratory, Clinic and Policlinic for Psychiatry, Psychosomatic and Psychotherapy, University of Wurzburg, Germany
    Atten Defic Hyperact Disord 2:225-32. 2010
    ..These data point to diverse effects of MPH on cell metabolism independent of inhibiting DAT...
  14. doi Genotoxicity of the neurotransmitter dopamine in vitro
    Helga Stopper
    Department of Toxicology, University of Wuerzburg, Versbacher Strasse 9, D 97078 Wuerzburg, Germany
    Toxicol In Vitro 23:640-6. 2009
    ....
  15. pmc Structural abnormality of the substantia nigra in children with attention-deficit hyperactivity disorder
    Marcel Romanos
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wuerzburg, Wuerzburg, Germany
    J Psychiatry Neurosci 35:55-8. 2010
    ..We investigated echogenicity of the substantia nigra as a potential structural marker for dysfunction of the nigrostriatal dopamine system in children with attention-deficit hyperactivity disorder (ADHD)...
  16. doi Does the treatment of maternal attention deficit and hyperactivity disorder (ADHD) enhance the efficacy of a behavioural parent training for the treatment of their children's ADHD? Study protocol of a randomized controlled multicentre trail
    Thomas Jans
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital, University of Wuerzburg, Germany
    Atten Defic Hyperact Disord 1:33-45. 2009
    ..Intention-to-treat analysis will be performed within a linear regression model (Current Controlled Trials ISRCTN73911400)...
  17. ncbi The relevance of iron in the pathogenesis of Parkinson's disease
    Mario E Götz
    Department of Pharmacology and Toxicology, University of Wurzburg, Germany
    Ann N Y Acad Sci 1012:193-208. 2004
    ..There are indications that iron-mediated neuronal death in PD proceeds retrogradely. These results are also discussed with respect to their relevance for disease progression in relation to cytotoxic alpha-synuclein protofibril formation...
  18. doi Expression analyses of the mitochondrial complex I 75-kDa subunit in early onset schizophrenia and autism spectrum disorder: increased levels as a potential biomarker for early onset schizophrenia
    Regina Taurines
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    Eur Child Adolesc Psychiatry 19:441-8. 2010
    ..Although further studies are necessary to test for the specificity of this marker, our findings point to the potential use of the mitochondrial complex I as a biomarker for schizophrenia...
  19. ncbi The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery
    Seong Wook Yun
    Institute of Virology and Immunobiology, University of Wurzburg, Wurzburg, Germany
    J Neurovirol 13:328-37. 2007
    ..However, neither intraperitoneal nor intracerebroventricular delivery of the drug exerted any PrP(Sc) clearance effect in the CNS...
  20. pmc Human stiff-person syndrome IgG induces anxious behavior in rats
    Christian Geis
    Department of Neurology, University of Wurzburg, Wurzburg, Germany
    PLoS ONE 6:e16775. 2011
    ..Most patients have high-titer antibodies against glutamate decarboxylase (GAD) 65. The pathogenic role of these autoantibodies is unclear...
  21. pmc 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, is responsible for complete Freund's adjuvant-induced thermal hyperalgesia in mice
    Yong Chen
    Department of Neurology, University of Wurzburg, Josef Schneider Strasse 11, Wurzburg 97080, Germany
    Mol Pain 7:21. 2011
    ..Previous work led to the hypothesis that 5-hydroxyindolacetic acid (5-HIAA), a main metabolite of serotonin, might by itself influence pain thresholds...
  22. doi Serotonin transporter deficiency protects mice from mechanical allodynia and heat hyperalgesia in vincristine neuropathy
    Niels Hansen
    Department of Neurology, University of Wurzburg, Josef Schneider Straße 11, 97080 Wurzburg, Germany
    Neurosci Lett 495:93-7. 2011
    ..Conversely, attenuation of mechanical allodynia in 5-HTT-/- mice may indicate reduced 5-HT-mediated facilitation in the central nervous system...
  23. pmc Identification of L-ferritin in neuromelanin granules of the human substantia nigra: a targeted proteomics approach
    Florian Tribl
    Clinic and Polyclinic for Psychiatry and Psychotherapy, Julius Maximilians Universitat Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
    Mol Cell Proteomics 8:1832-8. 2009
    ..Thus our finding entails far reaching implications especially when considering etiopathogenetic aspects of Parkinson disease...
  24. ncbi Entacapone increases and prolongs the central effects of l-DOPA in the 6-hydroxydopamine-lesioned rat
    Manfred Gerlach
    Laboratory of Clinical Neurochemistry, Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
    Naunyn Schmiedebergs Arch Pharmacol 370:388-94. 2004
    ....
  25. doi No increased chromosomal damage in L-DOPA-treated patients with Parkinson's disease: a pilot study
    Rajaraman Gnana Oli
    Department of Toxicology, University of Wuerzburg, Versbacher Strasse 9, 97078 Wuerzburg, Germany
    J Neural Transm 117:737-46. 2010
    ..On the other hand, the 8-oxodG concentration in cultured PC 12 cells was enhanced after dopamine treatment. This elevation may be below a threshold for manifestation as chromosomal damage...
  26. doi Pharmacotherapy in depressed children and adolescents
    Regina Taurines
    Hospital of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    World J Biol Psychiatry 12:11-5. 2011
    ..In the following overview we address a general framework, therapeutic strategies and the issues of antidepressant pharmacotherapy for the treatment of unipolar depression in childhood and adolescence...
  27. doi Improved odor sensitivity in attention-deficit/hyperactivity disorder
    Marcel Romanos
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Clinic of Wuerzburg, Wuerzburg, Germany
    Biol Psychiatry 64:938-40. 2008
    ..Because of the involvement of the dopamine system in the pathophysiology of attention-deficit/hyperactivity disorder (ADHD), olfactory function was investigated in children with the disorder...
  28. ncbi beta-Amyloid deposition and prion infection in adult primary brain cell long-term culture model
    Seong Wook Yun
    Clinical Neurochemistry and NPF Center of Excellence Laboratories, Clinic of Psychiatry and Psychotherapy, University of Wurzburg, 97080 Wurzburg, Germany
    Biochem Biophys Res Commun 360:520-4. 2007
    ..After long-term culture of adult primary brain cells prepared from Alzheimer's disease and prion disease mouse models, we observed beta-amyloid deposition and prion infection in primary cell cultures in vitro...
  29. ncbi Comparison analysis of gene expression patterns between sporadic Alzheimer's and Parkinson's disease
    Edna Grunblatt
    Neurochemistry Laboratory, National Parkinson Foundation Centre of Excellence Laboratories, Clinic and Policlinic for Psychiatry and Psychotherapy, University of Wurzburg, Germany
    J Alzheimers Dis 12:291-311. 2007
    ..Knowledge of selective gene expression profile can lead to better understanding of disease pathology and development of specific diagnosis and effective therapy...
  30. ncbi Relating mode of action to clinical practice: dopaminergic agents in Parkinson's disease
    Peter Riederer
    Klinische Neurochemie Universitätsklinik für Psychiatrie und Psychotherapie, Wurzburg, Germany
    Parkinsonism Relat Disord 13:466-79. 2007
    ..This article reviews the three main classes of dopaminergic PD therapy (levodopa, monoamine oxidase inhibitors and dopamine agonists)...
  31. ncbi Neuromelanin and its interaction with iron as a potential risk factor for dopaminergic neurodegeneration underlying Parkinson's disease
    Manfred Gerlach
    Clinical Neurochemistry, Department of Child and Youth Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, D 97080 Wurzburg, Germany
    Neurotox Res 5:35-44. 2003
    ..The resultant radical-mediated cytotoxicity may contribute to cellular damage observed in PD...
  32. doi Altered frontal and temporal brain function during olfactory stimulation in adult attention-deficit/hyperactivity disorder
    Martin Schecklmann
    Department of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wurzburg, University of Wurzburg, Wurzburg, Germany
    Neuropsychobiology 63:66-76. 2011
    ..Some investigations suggested alterations in olfactory processing (identification and sensitivity) in childhood and adult ADHD...
  33. ncbi Unaltered susceptibility to scrapie in serotonin transporter deficient mice
    Rainald Mossner
    Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstrasse 15, 97080 Wurzburg, Germany
    Neurochem Int 49:454-8. 2006
    ..These findings argue against a major role of the 5-HTT in the pathogenesis of prion diseases in mice...
  34. ncbi Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury
    Daniela Berg
    Department of Neurology, University of Wurzburg, Josef Schneider Str 11, 97080 Wurzburg, Germany
    Arch Neurol 59:999-1005. 2002
    ..The same echo feature of the SN can be identified in 9% of healthy adults...
  35. ncbi Preclinical versus clinical neuroprotection
    Edna Grunblatt
    Department of Neurochemistry, Clinic and Polyclinic of Psychiatry and Psychotherapy, Bayerische Julius Maximilians University of Würzburg, Wurzburg, Germany
    Adv Neurol 91:309-28. 2003
  36. pmc Neuromelanin is an immune stimulator for dendritic cells in vitro
    Uwe Oberländer
    University of Wurzburg, Institute of Virology and Immunobiology, Wurzburg, Germany
    BMC Neurosci 12:116. 2011
    ..This recognition of NM by DCs is a prerequisite to trigger an adaptive autoimmune response directed against NM-associated structures...
  37. doi Influence of a genetic variant of the neuronal growth associated protein Stathmin 1 on cognitive and affective control processes: an event-related potential study
    Ann Christine Ehlis
    Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Germany
    Am J Med Genet B Neuropsychiatr Genet 156:291-302. 2011
    ....
  38. doi Decreased anxiety in mice lacking the organic cation transporter 3
    Thomas Wultsch
    Section of Clinical and Molecular Psychobiology, Department of Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    J Neural Transm 116:689-97. 2009
    ....
  39. doi [The impact of attention deficit/hyperactivity disorder (ADHD) in mothers on the treatment of their ADHD children--review and summary of the study protocol of a randomized controlled multi-centre trial on parent training]
    Thomas Jans
    Klinik und Poliklinik für Kinder und Jugendpsychiatrie, Psychosomatik und Psychotherapie des Klinikums der Universität Würzburg, Fuchsleinstrasse 15, Wurzburg
    Z Kinder Jugendpsychiatr Psychother 36:335-43. 2008
    ..Treatment comparisons of the primary endpoint (externalizing symptoms in the children) will be performed within a linear regression model...
  40. ncbi Biochemical and pharmacological characterization of 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline: a biologically relevant neurotoxin?
    Peter Riederer
    Clinical Neurochemistry, Department of Psychiatry, University of Wurzburg, Fuchsleinstrasse 15, Wurzburg, Germany
    Eur J Pharmacol 442:1-16. 2002
    ..The biochemical and pharmacological characteristics of TaClo and related compounds are thus reviewed here, and their potential significance for human neurodegenerative disease discussed...
  41. ncbi [Therapy with lithium salts in child and adolescent psychiatry--clinical efficacy and practical recommendations]
    Manfred Gerlach
    Klinik für Kinder und Jugendpsychiatrie und Psychotherapie der Universität Würzburg
    Z Kinder Jugendpsychiatr Psychother 34:181-8; quiz 188-9. 2006
    ..5 mmol/l are dangerous. All potential side effects, with the exception of very infrequently occurring renal damage, are reversible by means of dose reduction or, if necessary, by discontinuation of medication with lithium...
  42. ncbi [Therapeutic drug monitoring in child and adolescent psychiatry--practical recommendations]
    Manfred Gerlach
    Klinik für Kinder und Jugendpsychiatrie und Psychotherapie der Universität Würzburg
    Z Kinder Jugendpsychiatr Psychother 34:5-13. 2006
    ..For a detailed treatment of TDM in psychiatry, the interested reader is referred to the AG-NP-TDM Expert Group Consensus Guidelines published earlier (Baumann et al., 2004)...
  43. ncbi "Subcellular proteomics" of neuromelanin granules isolated from the human brain
    Florian Tribl
    Department of Clinical Neurochemistry, Clinic and Polyclinic for Psychiatry and Psychotherapy, and The National Parkinson Foundation Research Laboratories, Miami, Florida, USA
    Mol Cell Proteomics 4:945-57. 2005
    ....
  44. doi The relation between dosage, serum concentrations, and clinical outcome in children and adolescents treated with sertraline: a naturalistic study
    Regina Taurines
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany
    Ther Drug Monit 35:84-91. 2013
    ....
  45. ncbi Postnatal brain development and psychotropic drugs. Effects on animals and animal models of depression and attention-deficit/hyperactivity disorder
    Nathalie Bock
    University of Goettingen, Germany, Department of Child and Adolescent Psychiatry, Von Siebold Str 5, 37075 Goettingen, Germany
    Curr Pharm Des 16:2474-83. 2010
    ....
  46. doi Association of attention-deficit/hyperactivity disorder and atopic eczema modified by sleep disturbance in a large population-based sample
    Marcel Romanos
    Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Clinic of Wuerzburg, Fuechsleinstr 15, 97080 Wuerzburg, Germany
    J Epidemiol Community Health 64:269-73. 2010
    ....
  47. ncbi Absence of thermal hyperalgesia in serotonin transporter-deficient mice
    Carola Vogel
    Department of Neurology, University of Wurzburg, 97080 Wurzburg, Germany
    J Neurosci 23:708-15. 2003
    ..In contrast, bilateral mechanical allodynia, a centrally mediated phenomenon, was associated with decreased spinal 5-HT concentrations in 5-HTT-/- mice and may possibly be caused by a lack of spinal inhibition...
  48. pmc Does methylphenidate cause a cytogenetic effect in children with attention deficit hyperactivity disorder?
    Susanne Walitza
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Wurzburg, Germany
    Environ Health Perspect 115:936-40. 2007
    ..Assessment and treatment of patients were performed during inpatient or outpatient health care. The measure for genomic damage was the frequency of micronuclei, a subset of chromosomal aberrations, in peripheral lymphocytes...
  49. doi Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition
    Christian Geis
    Department of Neurology, University of Wurzburg, Josef Schneider Str 11, 97080 Wurzburg, Germany
    Brain 133:3166-80. 2010
    ....
  50. pmc Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD?
    Veit Roessner
    Department of Child and Adolescent Psychiatry, University of Goettingen, Goettingen, Germany
    Behav Brain Funct 3:64. 2007
    ..abstract:..
  51. ncbi Increased mRNA levels of the mitochondrial complex I 75-kDa subunit. A potential peripheral marker of early onset schizophrenia?
    Claudia Mehler-Wex
    Dept of Child and Adolescent Psychiatry, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    Eur Child Adolesc Psychiatry 15:504-7. 2006
    ..Our preliminary findings suggest the mitochondrial complex I as a potential peripheral marker of schizophrenia and its involvement in the pathophysiology of this illness...
  52. doi Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system
    Susanne Walitza
    Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wurzburg, Fuchsleinstr 15, 97080 Wurzburg, Germany
    J Neural Transm 115:1071-8. 2008
    ..No evidence of transmission disequilibrium was detected for alleles of the DAT1 and COMT polymorphisms. These polymorphisms do not appear to play a major role in the genetic predisposition to early onset OCD in our study group...