Thilo Sprenger

Summary

Affiliation: Georg August University
Country: Germany

Publications

  1. pmc Preoperative chemoradiotherapy does not necessarily reduce lymph node retrieval in rectal cancer specimens--results from a prospective evaluation with extensive pathological work-up
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center Gottingen, Georg August University, Robert Koch Str 40, 37099 Gottingen, Germany
    J Gastrointest Surg 14:96-103. 2010
  2. doi request reprint Lymph node metastases in rectal cancer after preoperative radiochemotherapy: impact of intramesorectal distribution and residual micrometastatic involvement
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center Gottingen, Germany
    Am J Surg Pathol 37:1283-9. 2013
  3. doi request reprint Enrichment of CD133-expressing cells in rectal cancers treated with preoperative radiochemotherapy is an independent marker for metastasis and survival
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center, Goettingen, Germany
    Cancer 119:26-35. 2013
  4. doi request reprint Failure of downregulation of survivin following neoadjuvant radiochemotherapy in rectal cancer is associated with distant metastases and shortened survival
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center, Gottingen, Germany
    Clin Cancer Res 17:1623-31. 2011
  5. pmc Stage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: do we have indications for individual risk stratification?
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center Gottingen, Georg August University, Gottingen, Germany
    World J Surg Oncol 8:27. 2010
  6. pmc Thymidylate synthase as a prognostic biomarker for locally advanced rectal cancer after multimodal treatment
    Lena Christin Conradi
    Department of General and Visceral Surgery Department of General and Visceral Surgery, Göttingen University Medical Center, Gottingen, Germany
    Ann Surg Oncol 18:2442-52. 2011
  7. pmc Gender-specific acute organ toxicity during intensified preoperative radiochemotherapy for rectal cancer
    Hendrik A Wolff
    Department of Radiotherapy and Radiooncology, University Medical Center Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Oncologist 16:621-31. 2011
  8. doi request reprint Frequency of HER-2 positivity in rectal cancer and prognosis
    Lena Christin Conradi
    Department of General and Visceral Surgery, University Medical Center, Gottingen, Germany
    Am J Surg Pathol 37:522-31. 2013
  9. doi request reprint Optimal lymph node harvest in rectal cancer (UICC stages II and III) after preoperative 5-FU-based radiochemotherapy. Acetone compression is a new and highly efficient method
    Anastasia Gehoff
    Department of General, University Medical Center Gottingen, Gottingen, Germany
    Am J Surg Pathol 36:202-13. 2012
  10. pmc Ultrasonic scalpel causes greater depth of soft tissue necrosis compared to monopolar electrocautery at standard power level settings in a pig model
    Kia Homayounfar
    Department of General and Visceral Surgery, University Medical Center Goettingen, Georg August University, Germany
    BMC Surg 12:3. 2012

Collaborators

Detail Information

Publications10

  1. pmc Preoperative chemoradiotherapy does not necessarily reduce lymph node retrieval in rectal cancer specimens--results from a prospective evaluation with extensive pathological work-up
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center Gottingen, Georg August University, Robert Koch Str 40, 37099 Gottingen, Germany
    J Gastrointest Surg 14:96-103. 2010
    ..The objective of this prospective study was to determine the effects of chemoradiation on mesorectal lymph node retrieval under terms of a meticulous histopathological evaluation...
  2. doi request reprint Lymph node metastases in rectal cancer after preoperative radiochemotherapy: impact of intramesorectal distribution and residual micrometastatic involvement
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center Gottingen, Germany
    Am J Surg Pathol 37:1283-9. 2013
    ..Here we assessed the prognostic impact of residual LN micrometastases (<0.2 cm) and the intramesorectal distribution of LN metastases...
  3. doi request reprint Enrichment of CD133-expressing cells in rectal cancers treated with preoperative radiochemotherapy is an independent marker for metastasis and survival
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center, Goettingen, Germany
    Cancer 119:26-35. 2013
    ....
  4. doi request reprint Failure of downregulation of survivin following neoadjuvant radiochemotherapy in rectal cancer is associated with distant metastases and shortened survival
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center, Gottingen, Germany
    Clin Cancer Res 17:1623-31. 2011
    ....
  5. pmc Stage II/III rectal cancer with intermediate response to preoperative radiochemotherapy: do we have indications for individual risk stratification?
    Thilo Sprenger
    Department of General and Visceral Surgery, University Medical Center Gottingen, Georg August University, Gottingen, Germany
    World J Surg Oncol 8:27. 2010
    ..However, most patients show incomplete response. The aim of this investigation was to find indications for risk stratification in the group of intermediate responders to RCT...
  6. pmc Thymidylate synthase as a prognostic biomarker for locally advanced rectal cancer after multimodal treatment
    Lena Christin Conradi
    Department of General and Visceral Surgery Department of General and Visceral Surgery, Göttingen University Medical Center, Gottingen, Germany
    Ann Surg Oncol 18:2442-52. 2011
    ..In this study, we analyzed TS expression in the rectal cancer tissue of 208 patients to evaluate its predictive/prognostic potential...
  7. pmc Gender-specific acute organ toxicity during intensified preoperative radiochemotherapy for rectal cancer
    Hendrik A Wolff
    Department of Radiotherapy and Radiooncology, University Medical Center Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Oncologist 16:621-31. 2011
    ..These results suggest that there are basic clinical parameters, such as gender and body mass index, that may be potential markers for generating individual risk profiles of RCT-induced toxicity...
  8. doi request reprint Frequency of HER-2 positivity in rectal cancer and prognosis
    Lena Christin Conradi
    Department of General and Visceral Surgery, University Medical Center, Gottingen, Germany
    Am J Surg Pathol 37:522-31. 2013
    ..7%) of rectal cancer patients. For the development of innovative new therapies, HER-2 may represent a promising target and should be further assessed within prospective clinical trials...
  9. doi request reprint Optimal lymph node harvest in rectal cancer (UICC stages II and III) after preoperative 5-FU-based radiochemotherapy. Acetone compression is a new and highly efficient method
    Anastasia Gehoff
    Department of General, University Medical Center Gottingen, Gottingen, Germany
    Am J Surg Pathol 36:202-13. 2012
    ..Actual numbers of assessed LNs and validity of ypN status vary extensively depending on the methods used...
  10. pmc Ultrasonic scalpel causes greater depth of soft tissue necrosis compared to monopolar electrocautery at standard power level settings in a pig model
    Kia Homayounfar
    Department of General and Visceral Surgery, University Medical Center Goettingen, Georg August University, Germany
    BMC Surg 12:3. 2012
    ..However, morphological data on the related tissue alteration are discordant. We developed an automatic device for standardized sample excision and compared quality and depth of morphological changes caused by UC and ME in a pig model...