R Geisen

Summary

Country: Germany

Publications

  1. ncbi request reprint Cloning a part of the ochratoxin A biosynthetic gene cluster of Penicillium nordicum and characterization of the ochratoxin polyketide synthase gene
    Anja Karolewiez
    Federal Research Centre fbr Nutrition and Food, Haid und Neu Str 9, 76131 Karlsruhe, Germany
    Syst Appl Microbiol 28:588-95. 2005
  2. ncbi request reprint Development of a molecular detection and differentiation system for ochratoxin A producing Penicillium species and its application to analyse the occurrence of Penicillium nordicum in cured meats
    Caroline Bogs
    Federal Research Centre for Nutrition and Food, Location Karlsruhe, Haid und Neu Str 9, 76351 Karlsruhe, Germany
    Int J Food Microbiol 107:39-47. 2006
  3. ncbi request reprint Physiological relationship between food preservatives, environmental factors, ochratoxin and otapksPV gene expression by Penicillium verrucosum
    Markus Schmidt-Heydt
    Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Int J Food Microbiol 119:277-83. 2007
  4. ncbi request reprint Inhibition of food-related pathogenic bacteria by god-transformed Penicillium nalgiovense strains
    R Geisen
    Federal Research Centre for Nutrition, Karlsruhe, Germany
    J Food Prot 62:940-3. 1999
  5. ncbi request reprint Development of a Real Time PCR system for detection of Penicillium nordicum and for monitoring ochratoxin A production in foods by targeting the ochratoxin polyketide synthase gene
    Rolf Geisen
    Federal Research Centre for Nutrition and Food, Institute of Hygiene and Toxicology, Karlsruhe, Germany
    Syst Appl Microbiol 27:501-7. 2004
  6. ncbi request reprint Molecular monitoring of environmental conditions influencing the induction of ochratoxin A biosynthesis genes in Penicillium nordicum
    Rolf Geisen
    Federal Research Centre for Nutrition and Food, Location Karlsruhe, Karlsruhe, Germany
    Mol Nutr Food Res 48:532-40. 2004
  7. ncbi request reprint P. nalgiovense carries a gene which is homologous to the paf gene of P. chrysogenum which codes for an antifungal peptide
    R Geisen
    Federal Research Centre for Nutrition, Karlsruhe, Germany
    Int J Food Microbiol 62:95-101. 2000
  8. doi request reprint Comprehensive molecular system to study the presence, growth and ochratoxin A biosynthesis of Penicillium verrucosum in wheat
    M Schmidt-Heydt
    Max Rubner Institute Federal Research Centre of Nutrition and Food, Karlsruhe, Germany
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:989-96. 2008
  9. ncbi request reprint Taxonomy and important features of probiotic microorganisms in food and nutrition
    W H Holzapfel
    Institute of Hygiene and Toxicology, BFE Karlsruhe, Germany
    Am J Clin Nutr 73:365S-373S. 2001
  10. ncbi request reprint Characterization of Penicillium roqueforti strains used as cheese starter cultures by RAPD typing
    R Geisen
    Federal Research Centre for Nutrition, Institute for Hygiene and Toxicology, Karlsruhe, Germany
    Int J Food Microbiol 65:183-91. 2001

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Cloning a part of the ochratoxin A biosynthetic gene cluster of Penicillium nordicum and characterization of the ochratoxin polyketide synthase gene
    Anja Karolewiez
    Federal Research Centre fbr Nutrition and Food, Haid und Neu Str 9, 76131 Karlsruhe, Germany
    Syst Appl Microbiol 28:588-95. 2005
    ..verrucosum, but not in other species. An inactivation of the polyketide synthase resulted in strains with abolished capacity to produce ochratoxin A. Expression of the polyketide synthase correlates with ochratoxin A biosynthesis...
  2. ncbi request reprint Development of a molecular detection and differentiation system for ochratoxin A producing Penicillium species and its application to analyse the occurrence of Penicillium nordicum in cured meats
    Caroline Bogs
    Federal Research Centre for Nutrition and Food, Location Karlsruhe, Haid und Neu Str 9, 76351 Karlsruhe, Germany
    Int J Food Microbiol 107:39-47. 2006
    ..nalgiovense strains however produced detectable amounts of ochratoxin A. A more detailed analysis revealed that P. nalgiovense carries similar but non-transcribed sequences to the ochratoxin A biosynthetic genes of P. nordicum...
  3. ncbi request reprint Physiological relationship between food preservatives, environmental factors, ochratoxin and otapksPV gene expression by Penicillium verrucosum
    Markus Schmidt-Heydt
    Federal Research Centre for Nutrition and Food, Karlsruhe, Germany
    Int J Food Microbiol 119:277-83. 2007
    ..This is the first time that genotypic information has been linked to phenotypic mycotoxin production in relation to such interacting stress factors...
  4. ncbi request reprint Inhibition of food-related pathogenic bacteria by god-transformed Penicillium nalgiovense strains
    R Geisen
    Federal Research Centre for Nutrition, Karlsruhe, Germany
    J Food Prot 62:940-3. 1999
    ..If catalase was added to the medium, the inhibitory activity of the transformants was completely inactivated, indicating that the hydrogen peroxide produced was responsible for the antibacterial activity of the transformants...
  5. ncbi request reprint Development of a Real Time PCR system for detection of Penicillium nordicum and for monitoring ochratoxin A production in foods by targeting the ochratoxin polyketide synthase gene
    Rolf Geisen
    Federal Research Centre for Nutrition and Food, Institute of Hygiene and Toxicology, Karlsruhe, Germany
    Syst Appl Microbiol 27:501-7. 2004
    ..According to these results the fragment is obviously part of a polyketide synthase (otapksPN) which seems to be involved in the production of ochratoxin A...
  6. ncbi request reprint Molecular monitoring of environmental conditions influencing the induction of ochratoxin A biosynthesis genes in Penicillium nordicum
    Rolf Geisen
    Federal Research Centre for Nutrition and Food, Location Karlsruhe, Karlsruhe, Germany
    Mol Nutr Food Res 48:532-40. 2004
    ..nordicum could be observed at the different temperatures, showing highest production at 25 degrees C. The importance of these data are discussed with reference to the natural habitat of P. nordicum...
  7. ncbi request reprint P. nalgiovense carries a gene which is homologous to the paf gene of P. chrysogenum which codes for an antifungal peptide
    R Geisen
    Federal Research Centre for Nutrition, Karlsruhe, Germany
    Int J Food Microbiol 62:95-101. 2000
    ..When P. nalgiovense were grown on plates containing other food-relevant fungi it showed weak antifungal activity...
  8. doi request reprint Comprehensive molecular system to study the presence, growth and ochratoxin A biosynthesis of Penicillium verrucosum in wheat
    M Schmidt-Heydt
    Max Rubner Institute Federal Research Centre of Nutrition and Food, Karlsruhe, Germany
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:989-96. 2008
    ..Reasonable amounts of ochratoxin A, however, could not be detected before day 30. This early activation of ochratoxin A related genes was confirmed by microarray analysis...
  9. ncbi request reprint Taxonomy and important features of probiotic microorganisms in food and nutrition
    W H Holzapfel
    Institute of Hygiene and Toxicology, BFE Karlsruhe, Germany
    Am J Clin Nutr 73:365S-373S. 2001
    ....
  10. ncbi request reprint Characterization of Penicillium roqueforti strains used as cheese starter cultures by RAPD typing
    R Geisen
    Federal Research Centre for Nutrition, Institute for Hygiene and Toxicology, Karlsruhe, Germany
    Int J Food Microbiol 65:183-91. 2001
    ..In addition, one of the primer (ari1) was able to distinguish between P. roqueforti strains producing larger or smaller numbers of metabolites...
  11. doi request reprint A gene cluster of the ochratoxin A biosynthetic genes inPenicillium
    R Geisen
    Federal Research Centre for Nutrition and Food, Location Karlsruhe, Haid und Neu Str 9, 76131, Karlsruhe, Germany
    Mycotoxin Res 22:134-41. 2006
    ..nordicum. P. nalgiovense, a species occurring in the same habitat asP. nordicum carries inactive homologues of the genes. All other species proved to be negative for the genes. This was also true for OTA producing Aspergilli...
  12. doi request reprint Stress induction of mycotoxin biosynthesis genes by abiotic factors
    Markus Schmidt-Heydt
    Max Rubner Institute, Karlsruhe, Germany
    FEMS Microbiol Lett 284:142-9. 2008
    ..Expression of the mycotoxin biosynthesis genes was followed exactly by phenotypic mycotoxin production. This expression profile appears to be generic across the mycotoxigenic fungi examined...
  13. pmc Monitoring the production of aflatoxin B1 in wheat by measuring the concentration of nor-1 mRNA
    Zsuzsanna Mayer
    Faculty of Food Science, Szent Itsván University, 1118 Budapest, Hungary
    Appl Environ Microbiol 69:1154-8. 2003
    ..The numbers of nor-1 gene copies increased at the beginning of the incubation and reached a plateau at day 5. They correlate well with the viable counts albeit at a higher level...
  14. ncbi request reprint Quantification of the copy number of nor-1, a gene of the aflatoxin biosynthetic pathway by real-time PCR, and its correlation to the cfu of Aspergillus flavus in foods
    Zsuzsanna Mayer
    Faculty of Food Science, Szent Itsván University, Villányi út 35 43, 1118 Budapest, Hungary
    Int J Food Microbiol 82:143-51. 2003
    ..In general, a good correlation between nor-1 gene copy number and the cfu data was observed; however, the nor-1 copy numbers were always higher. It was shown that the system is specific for nor-1 containing species...
  15. ncbi request reprint A microarray for monitoring the production of mycotoxins in food
    Markus Schmidt-Heydt
    Federal Research Centre for Nutrition and Food, Location Karlsruhe, Haid und Neu Str 9 76131 Karlsruhe, Germany
    Int J Food Microbiol 117:131-40. 2007
    ..An expression pattern indicative for trichothecene biosynthesis could be identified...
  16. ncbi request reprint Molecular characterization of ochratoxin A producing strains of the genus Penicillium
    Gemma Castella
    Dept Sanitat i Anatomia Animals, Facultat de Veterinaria, Universitat Autòmoma de Barcelona, Spain
    Syst Appl Microbiol 25:74-83. 2002
    ..verrucosum or P. nordicum. The homolgy between the ITS sequences however indicates phylogenetic relationship between the two species...