Gerd Geerling

Summary

Country: Germany

Publications

  1. ncbi request reprint Toxicity of natural tear substitutes in a fully defined culture model of human corneal epithelial cells
    G Geerling
    Moorfields Eye Hospital and the Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 42:948-56. 2001
  2. ncbi request reprint Sight and comfort: complex procedures in end-stage Stevens-Johnson syndrome
    G Geerling
    Moorfields Eye Hospital, London, UK
    Eye (Lond) 17:89-91. 2003
  3. pmc Autologous serum eye drops for ocular surface disorders
    G Geerling
    Department of Ophthalmology, University of Lubeck, Ratzeburger Allee 160, D 23538, Germany
    Br J Ophthalmol 88:1467-74. 2004
  4. ncbi request reprint Intraoperative 2-dimensional optical coherence tomography as a new tool for anterior segment surgery
    Gerd Geerling
    Department of Ophthalmology, Medical University of Lubeck, Lubeck, Germany
    Arch Ophthalmol 123:253-7. 2005
  5. ncbi request reprint Adnexal surgery for severe ocular surface disease
    Gerd Geerling
    Department of Ophthalmology, University of Lubeck, Lubeck, Germany
    Semin Ophthalmol 20:101-12. 2005
  6. ncbi request reprint [Keratoplasty -- a simple classification/terminology of current treatment options]
    G Geerling
    Klinik fur Augenheilkunde, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Klin Monbl Augenheilkd 222:612-4. 2005
  7. doi request reprint Evaluation of human MRC-5 cells as a feeder layer in a xenobiotic-free culture system for conjunctival epithelial progenitor cells
    Stefan Schrader
    Cells for Sight Transplantation and Research Programme Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Curr Eye Res 37:1067-74. 2012
  8. ncbi request reprint Corneal epitheliotrophic capacity of three different blood-derived preparations
    Lei Liu
    Department of Ophthalmology, University of Lubeck, Germany
    Invest Ophthalmol Vis Sci 47:2438-44. 2006
  9. doi request reprint Simulation of an in vitro niche environment that preserves conjunctival progenitor cells
    Stefan Schrader
    Cells for Sight Transplantation and Research Programme, Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Regen Med 5:877-89. 2010
  10. doi request reprint Effect of various platelet preparations on retinal muller cells
    Susanne L Burmeister
    Department of Ophthalmology, University of Lubeck, Lubeck, Germany
    Invest Ophthalmol Vis Sci 50:4881-6. 2009

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Toxicity of natural tear substitutes in a fully defined culture model of human corneal epithelial cells
    G Geerling
    Moorfields Eye Hospital and the Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 42:948-56. 2001
    ....
  2. ncbi request reprint Sight and comfort: complex procedures in end-stage Stevens-Johnson syndrome
    G Geerling
    Moorfields Eye Hospital, London, UK
    Eye (Lond) 17:89-91. 2003
    ..We describe our complex surgical techniques in the management of a patient with end-stage ocular surface disease from Stevens-Johnson syndrome...
  3. pmc Autologous serum eye drops for ocular surface disorders
    G Geerling
    Department of Ophthalmology, University of Lubeck, Ratzeburger Allee 160, D 23538, Germany
    Br J Ophthalmol 88:1467-74. 2004
    ..In view of legislative restrictions and based upon the literature reviewed here a preliminary standard operating procedure for the manufacture of serum eye drops is proposed...
  4. ncbi request reprint Intraoperative 2-dimensional optical coherence tomography as a new tool for anterior segment surgery
    Gerd Geerling
    Department of Ophthalmology, Medical University of Lubeck, Lubeck, Germany
    Arch Ophthalmol 123:253-7. 2005
    ..It is particularly helpful for lamellar dissection techniques such as deep anterior lamellar keratoplasty and trabeculectomy...
  5. ncbi request reprint Adnexal surgery for severe ocular surface disease
    Gerd Geerling
    Department of Ophthalmology, University of Lubeck, Lubeck, Germany
    Semin Ophthalmol 20:101-12. 2005
    ..In the presence of these problems, surgical attempts of ocular surface reconstruction frequently fail. Here we review established and evolving new techniques in the field of adnexal surgery to specifically address these problems...
  6. ncbi request reprint [Keratoplasty -- a simple classification/terminology of current treatment options]
    G Geerling
    Klinik fur Augenheilkunde, Universitatsklinikum Schleswig Holstein, Campus Lubeck
    Klin Monbl Augenheilkd 222:612-4. 2005
    ....
  7. doi request reprint Evaluation of human MRC-5 cells as a feeder layer in a xenobiotic-free culture system for conjunctival epithelial progenitor cells
    Stefan Schrader
    Cells for Sight Transplantation and Research Programme Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Curr Eye Res 37:1067-74. 2012
    ....
  8. ncbi request reprint Corneal epitheliotrophic capacity of three different blood-derived preparations
    Lei Liu
    Department of Ophthalmology, University of Lubeck, Germany
    Invest Ophthalmol Vis Sci 47:2438-44. 2006
    ..To test whether FFP or platelet-derived growth factor solutions could be used for ocular surface diseases, we compared the epitheliotrophic capacity of platelet releasate and FFP with that of serum in cell culture models...
  9. doi request reprint Simulation of an in vitro niche environment that preserves conjunctival progenitor cells
    Stefan Schrader
    Cells for Sight Transplantation and Research Programme, Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Regen Med 5:877-89. 2010
    ..To evaluate a serum-free system where mitotically active subconjunctival fibroblasts were co-cultured with conjunctival epithelial cells to mimic a niche environment for conjunctival progenitor cells...
  10. doi request reprint Effect of various platelet preparations on retinal muller cells
    Susanne L Burmeister
    Department of Ophthalmology, University of Lubeck, Lubeck, Germany
    Invest Ophthalmol Vis Sci 50:4881-6. 2009
    ....
  11. doi request reprint Clinical trials of therapeutic ocular surface medium for moderate to severe dry eye
    Stephanie L Watson
    Cornea and External Diseases, Moorfields Eye Hospital, London, United Kingdom
    Cornea 29:1241-6. 2010
    ..To investigate therapeutic ocular surface medium (TOSM), a potential physiological tear replacement therapy, for moderate to severe dry eye...
  12. doi request reprint Nourish and nurture: development of a nutrient ocular lubricant
    Lei Liu
    Department of Ophthalmology, University of Lubeck, Lubeck, Germany
    Invest Ophthalmol Vis Sci 50:2932-9. 2009
    ..The authors aimed to produce a new tear substitute capable of providing both lubrication and nutrition, based on a novel nutrient-containing therapeutic ocular surface medium (TOSM)...
  13. ncbi request reprint Filtering bleb evaluation with slit-lamp-adapted 1310-nm optical coherence tomography
    Maya Müller
    University Eye Hospital Schleswig Holstein, Lubeck, Germany
    Curr Eye Res 31:909-15. 2006
    ..Investigation of slit-lamp-adapted 1310-nm optical coherence tomography (OCT) as an in vivo imaging device in the postoperative course of glaucoma surgery...
  14. ncbi request reprint Anterior chamber angle measurement with optical coherence tomography: intraobserver and interobserver variability
    Maya Müller
    Eye Clinic, UK S H, Campus Lubeck, Lubeck, Germany
    J Cataract Refract Surg 32:1803-8. 2006
    ..To assess intraobserver and interobserver variability of anterior segment optical coherence tomography (AS-OCT) as an objective diagnostic tool to quantify the anterior chamber angle and opening width...
  15. ncbi request reprint Combination of serum eye drops with hydrogel bandage contact lenses in the treatment of persistent epithelial defects
    Stefan Schrader
    Department of Ophthalmology, UK SH Campus Lübeck, Klinik fur Augenheilkunde, Ratzeburger Allee 160, 23538, Lubeck, Germany
    Graefes Arch Clin Exp Ophthalmol 244:1345-9. 2006
    ..We report six eyes (five patients) which were all treated with autologous serum eye drops in combination with an FDA group IV hydrogel contact lens...
  16. ncbi request reprint Pharmacological prevention of radiation-induced dry eye-an experimental study in a rabbit model
    Julia Beutel
    Department of Ophthalmology, University Hospital Schleswig Holstein, Luebeck, Germany
    Graefes Arch Clin Exp Ophthalmol 245:1347-55. 2007
    ..To evaluate the radioprotective effect of lidocaine, amifostine and pilocarpine on lacrimal glands...
  17. doi request reprint Transplantation of the major salivary glands
    Gerd Geerling
    Department of Ophthalmology, University of Wurzburg, Wurzburg, Germany
    Dev Ophthalmol 41:255-68. 2008
    ..In this group of patients the three major salivary glands, the parotid, the submandibular and the sublingual gland, have been used to lubricate the ocular surface...
  18. doi request reprint In vitro characterization and ex vivo surgical evaluation of human hair keratin films in ocular surface reconstruction after sterilization processing
    Maria Borrelli
    Department of Ophthalmology, University of Duesseldorf, Dusseldorf, Germany
    J Mater Sci Mater Med 24:221-30. 2013
    ..However material modifications are requested before KF may represent a feasible alternative for ocular surface reconstruction...
  19. doi request reprint Decellularized porcine derived membrane (Tarsys®) for correction of lower eyelid retraction
    Maria Borrelli
    Department of Ophthalmology, University of Dusseldorf, Dusseldorf, Germany
    Orbit 31:187-9. 2012
    ....
  20. doi request reprint Tissue engineering for conjunctival reconstruction: established methods and future outlooks
    Stefan Schrader
    Cells for Sight Transplantation and Research Programme, Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Curr Eye Res 34:913-24. 2009
    ..This article reviews the present approaches for reconstruction of the conjunctival surface, considering the established strategies and new potential methodologies...
  21. pmc Early and late immunohistochemical and ultrastructural changes associated with functional impairment of the lachrymal gland following external beam radiation
    Samer G Hakim
    Department of Maxillofacial Surgery, University Hospital Schleswig Holstein, Luebeck, Germany
    Int J Exp Pathol 87:65-71. 2006
    ..These changes may represent objective surrogate parameters for radiogenic dysfunction and prerequisites for further investigations on radioprotection of lachrymal glands during radiotherapy of the periorbital region...
  22. doi request reprint Innervation and secretory function of transplanted human submandibular salivary glands
    Gerd Geerling
    Department of Ophthalmology, University of Wuerzburg, Wuerzburg, Germany
    Transplantation 85:135-40. 2008
    ..This shows that submandibular glands can remain viable despite complete separation from their normal nerve supply and are capable of regaining a substantial secretory activity for years...
  23. doi request reprint Minor salivary gland transplantation
    Gerd Geerling
    Department of Ophthalmology, University of Wurzburg, Wurzburg, Germany
    Dev Ophthalmol 41:243-54. 2008
    ..They can be transplanted together with the overlying mucosa as a complex graft to the posterior lamella of the eyelids to increase ocular surface lubrication and reduce discomfort in dry eyes...
  24. doi request reprint Surgical occlusion of the lacrimal drainage system
    Gerd Geerling
    Department of Ophthalmology, University of Wurzburg, Wurzburg, Germany
    Dev Ophthalmol 41:213-29. 2008
    ..Here we review current irreversible and reversible techniques to occlude the lacrimal drainage and describe a new surgical technique, termed 'punctum switch', which has the advantage of being permanent and yet potentially is reversible...
  25. doi request reprint Animal models of dry eye
    Stefan Schrader
    Department of Ophthalmology, University Hospital Schleswig Holstein, Campus Lubeck, Lubeck, Germany
    Dev Ophthalmol 41:298-312. 2008
    ..Understanding the characteristics and limitations of these models will help researchers choose the right models to address specific problems and develop new treatment modalities in dry eye...
  26. doi request reprint Flow chart on surgical approaches to dry eye
    Gerd Geerling
    Department of Ophthalmology, University of Wurzburg, Wurzburg, Germany
    Dev Ophthalmol 41:313-6. 2008
    ..Based on the type and severity of dry eye, we propose a structured approach to the surgical management of the disease...
  27. ncbi request reprint Epitheliotrophic capacity of a growth factor preparation produced from platelet concentrates on corneal epithelial cells: a potential agent for the treatment of ocular surface defects?
    Dirk Hartwig
    Institute of Immunology and Transfusion Medicine, Department of Ophthalmology, Institute of Anatomy, University of Luebeck, Luebeck, Germany
    Transfusion 44:1724-31. 2004
    ..Platelets (PLTs) are rich in growth factors and easily available as PLT concentrates (PCs) from blood banks. Therefore, growth factor preparations from PCs may serve as a new and superior therapeutic agent for such defects...
  28. doi request reprint Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable
    Claus Cursiefen
    Department of Ophthalmology, University of Cologne, Joseph Stelzmann Strasse 9 50924, Cologne, Germany
    Br J Ophthalmol 96:3-9. 2012
    ..In this review, we formulate a consensus on the unmet medical needs in the management of corneal neovascularisation and outline a framework for the clinical research that is needed to identify suitable agents to meet these needs...
  29. doi request reprint Leiomyolipoma of the orbit
    Maria Borrelli
    Department of Ophthalmology, University of Wurzburg, Wurzburg, Germany
    Ophthal Plast Reconstr Surg 28:e21-3. 2012
    ..Although it is very rare, ophthalmologists should consider leiomyolipoma in the differential diagnosis of orbital tumors. The long-term prognosis for patients affected by this benign tumor is good...
  30. doi request reprint Influence of corneal collagen crosslinking with riboflavin and ultraviolet-a irradiation on excimer laser surgery
    Daniel Kampik
    Department of Ophthalmology, University of Wurzburg, Wurzburg, Germany
    Invest Ophthalmol Vis Sci 51:3929-34. 2010
    ..This study was conducted to investigate whether CXL influences ablation rate, flap thickness, and refractive results of excimer laser procedures ex vivo...
  31. ncbi request reprint Temporal and spatial expression of matrix metalloproteinases during wound healing of human corneal tissue
    Julie T Daniels
    Epithelial Repair and Regeneration Group, Wound Healing Research Unit, Division of Pathology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, UK
    Exp Eye Res 77:653-64. 2003
    ..This study demonstrates matrix metalloproteinase expression in epithelial and fibroblast-like cells following wounding of human corneal tissue in culture where the cells remain in contact with their natural matrices...
  32. doi request reprint Mechanical pump dacryoreservoirs
    Juan Murube
    Clinica Murube, Madrid, Spain
    Dev Ophthalmol 41:269-82. 2008
    ..A new option is the implantable pump dacryoreservoir...
  33. doi request reprint Plugs for occlusion of the lacrimal drainage system
    Frank H W Tost
    University Eye Hospital, Greifswald, Germany
    Dev Ophthalmol 41:193-212. 2008
    ..A temporary block is usually induced by implants to tamponade on the level of the lacrimal puncta or canaliculi...
  34. ncbi request reprint Gene transfer to trabecular meshwork endothelium via direct injection into the Schlemm canal and in vivo toxicity study
    Tobias Hudde
    Zentrum für Augenheilkunde, Abteilung für Erkrankungen des vorderen Augenabschnitts, Essen, Germany
    Curr Eye Res 30:1051-9. 2005
    ..Our aim was to investigate the efficiency of adenoviral gene transfer via direct injection into the Schlemm canal ex vivo in human donor eyes and to examine the effect of human MMP-3 transgene expression in a rat model in vivo...
  35. ncbi request reprint Differential expression of vascular endothelial growth factor implies the limbal origin of pterygia
    Matthias Gebhardt
    Department of Anatomy, Christian Albrecht University of Kiel, Kiel, Germany
    Ophthalmology 112:1023-30. 2005
    ..To study the distribution of isoforms of vascular endothelial growth factor (VEGF) and its receptors VEGFR1 and VEGFR2 in pterygia and to compare it with that in healthy conjunctivas...