Jan Galle

Summary

Country: Germany

Publications

  1. pmc Comparison of the Effects of Pioglitazone versus Placebo when Given in Addition to Standard Insulin Treatment in Patients with Type 2 Diabetes Mellitus Requiring Hemodialysis: Results from the PIOren Study
    Jan Galle
    Klinik für Nephrologie und Dialyseverfahren, Klinikum Lüdenscheid, Ludenscheid, Germany
    Nephron Extra 2:104-14. 2012
  2. pmc An observational cohort study of extended dosing (once every 2 weeks or once monthly) regimens with darbepoetin alfa in patients with chronic kidney disease not on dialysis: the EXTEND study
    Jan Christoph Galle
    Klinik für Nephrologie und Dialyseverfahren, Klinikum Lüdenscheid, Ludenscheid, Germany
    Nephrol Dial Transplant 27:2303-11. 2012
  3. doi request reprint [Cardiorenal syndrome]
    Jan Galle
    Klinik für Nephrologie und Dialyseverfahren, Klinikum Lüdenscheid, Ludenscheid
    Med Klin (Munich) 105:142-9. 2010
  4. doi request reprint Reduction of proteinuria with angiotensin receptor blockers
    Jan Galle
    Department of Nephrology and Dialysis at Klinikum Lüdenscheid, Ludenscheid, Germany
    Nat Clin Pract Cardiovasc Med 5:S36-43. 2008
  5. doi request reprint Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy
    Jan Galle
    Department of Internal Medicine, University Hospital, Wurzburg, Germany
    Nephrol Dial Transplant 23:3174-83. 2008
  6. ncbi request reprint L-Arginine does not affect renal morphology and cell survival in ischemic acute renal failure in rats
    Ulrike Raff
    Division of Nephrology, Department of Medicine, Julius Maximilian University, Wurzburg, Germany
    Nephron Physiol 101:p39-50. 2005
  7. doi request reprint Monomeric C-reactive protein decreases acetylated LDL uptake in human endothelial cells
    Susanne B Schwedler
    Department of Medicine I, University of Wurzburg, Wurzburg, Germany
    Clin Chem 55:1728-31. 2009
  8. ncbi request reprint L-Arginine counteracts nitric oxide deficiency and improves the recovery phase of ischemic acute renal failure in rats
    Reinhard Schneider
    Division of Nephrology, Department of Medicine, Julius Maximilians University, Wurzburg, Germany
    Kidney Int 64:216-25. 2003
  9. ncbi request reprint Impact of oxidized low density lipoprotein on vascular cells
    Jan Galle
    Department of Medicine, Division of Nephrology, Julius Maximilians University, Wurzburg, Germany
    Atherosclerosis 185:219-26. 2006
  10. ncbi request reprint [Atherosclerosis and arteriitis: implications for therapy of cardiovascular disease]
    Jan Galle
    Medizinische Klinik der Universität Würzburg, Wurzburg, Germany
    Herz 29:4-11. 2004

Collaborators

Detail Information

Publications18

  1. pmc Comparison of the Effects of Pioglitazone versus Placebo when Given in Addition to Standard Insulin Treatment in Patients with Type 2 Diabetes Mellitus Requiring Hemodialysis: Results from the PIOren Study
    Jan Galle
    Klinik für Nephrologie und Dialyseverfahren, Klinikum Lüdenscheid, Ludenscheid, Germany
    Nephron Extra 2:104-14. 2012
    ..The aim of this study was to investigate the effect of pioglitazone versus placebo on total daily insulin requirements and several pleiotropic factors in type 2 diabetes patients requiring hemodialysis...
  2. pmc An observational cohort study of extended dosing (once every 2 weeks or once monthly) regimens with darbepoetin alfa in patients with chronic kidney disease not on dialysis: the EXTEND study
    Jan Christoph Galle
    Klinik für Nephrologie und Dialyseverfahren, Klinikum Lüdenscheid, Ludenscheid, Germany
    Nephrol Dial Transplant 27:2303-11. 2012
    ..EXTEND is an observational study assessing the effectiveness of DA administered once biweekly (Q2W) or monthly (QM) in a general CKD-NoD population...
  3. doi request reprint [Cardiorenal syndrome]
    Jan Galle
    Klinik für Nephrologie und Dialyseverfahren, Klinikum Lüdenscheid, Ludenscheid
    Med Klin (Munich) 105:142-9. 2010
    ..Such a differentiation is helpful to find the appropriate therapeutic approach, according to the underlying disease. Therefore, the new classification and modern therapeutic concepts shall be presented here...
  4. doi request reprint Reduction of proteinuria with angiotensin receptor blockers
    Jan Galle
    Department of Nephrology and Dialysis at Klinikum Lüdenscheid, Ludenscheid, Germany
    Nat Clin Pract Cardiovasc Med 5:S36-43. 2008
    ..These data support the proposition that blockade of the renin-angiotensin system beyond that required for maximum blood pressure reduction provides optimum renal protection...
  5. doi request reprint Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy
    Jan Galle
    Department of Internal Medicine, University Hospital, Wurzburg, Germany
    Nephrol Dial Transplant 23:3174-83. 2008
    ..Experimental evidence demonstrates that angiotensin receptor blockers (ARBs) possess anti-inflammatory potential, which might contribute to reducing proteinuria and providing renoprotection...
  6. ncbi request reprint L-Arginine does not affect renal morphology and cell survival in ischemic acute renal failure in rats
    Ulrike Raff
    Division of Nephrology, Department of Medicine, Julius Maximilian University, Wurzburg, Germany
    Nephron Physiol 101:p39-50. 2005
    ..L-Arginine (L-Arg), a substrate of nitric oxide synthases, improves renal function in ischemic acute renal failure (iARF). We evaluated whether L-Arg improves renal morphology and cell survival in the course of iARF...
  7. doi request reprint Monomeric C-reactive protein decreases acetylated LDL uptake in human endothelial cells
    Susanne B Schwedler
    Department of Medicine I, University of Wurzburg, Wurzburg, Germany
    Clin Chem 55:1728-31. 2009
    ..Here, we tested the impact of mCRP and nCRP on the uptake of acetylated LDL (acLDL), which is internalized by receptors similar to those of oxLDL in human endothelial cells...
  8. ncbi request reprint L-Arginine counteracts nitric oxide deficiency and improves the recovery phase of ischemic acute renal failure in rats
    Reinhard Schneider
    Division of Nephrology, Department of Medicine, Julius Maximilians University, Wurzburg, Germany
    Kidney Int 64:216-25. 2003
    ..Here we further analyzed the impact of l-Arg on functional and biochemical parameters of nitric oxide signaling during the course of ischemic ARF...
  9. ncbi request reprint Impact of oxidized low density lipoprotein on vascular cells
    Jan Galle
    Department of Medicine, Division of Nephrology, Julius Maximilians University, Wurzburg, Germany
    Atherosclerosis 185:219-26. 2006
    ..Thus, through a variety of mechanisms, OxLDL importantly contributes to vascular dysfunction and remodeling...
  10. ncbi request reprint [Atherosclerosis and arteriitis: implications for therapy of cardiovascular disease]
    Jan Galle
    Medizinische Klinik der Universität Würzburg, Wurzburg, Germany
    Herz 29:4-11. 2004
    ....
  11. ncbi request reprint Inflammation in uremic patients: what is the link?
    Jan Galle
    Department of Medicine, Division of Nephrology, University of Wurzburg, Wurzburg, Germany
    Kidney Blood Press Res 26:65-75. 2003
    ..Based on pathophysiological considerations valid for uremic patients, we discuss therapeutical options that might help to reduce cardiovascular disease in uremic patients...
  12. ncbi request reprint Native C-reactive protein increases whereas modified C-reactive protein reduces atherosclerosis in apolipoprotein E-knockout mice
    Susanne B Schwedler
    Division of Nephrology, Department of Medicine, University of Wurzburg, Wurzburg, Germany
    Circulation 112:1016-23. 2005
    ..We tested the hypothesis that the configuration of CRP (pentameric, or native [nCRP], versus monomeric, or modified [mCRP]) determines these different characteristics in an in vivo model...
  13. ncbi request reprint Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA
    Jan Galle
    Department of Medicine, Julius Maximilians Universitat, Wurzburg, Germany
    J Am Soc Nephrol 14:1471-9. 2003
    ..Lysophosphatidylcholine mimics the OxLDL effect, consistent with a causal role of this OxLDL compound. Stimulation of RhoA by OxLDL may contribute to vasospasm in atherosclerotic arteries...
  14. ncbi request reprint Increase in nitric oxide bioavailability improves endothelial function in endothelin-1 transgenic mice
    Thomas Quaschning
    Department of Medicine, Division of Nephrology, University Hospital of Wurzburg, Wurzburg, Germany
    Nephrol Dial Transplant 18:479-83. 2003
    ..We thus hypothesized that vascular ET-1 effects may be antagonized by increased activity of other regulatory systems, such as the increase in bioavailability of the endothelial counterpart of ET-1, nitric oxide (NO)...
  15. ncbi request reprint C-reactive protein: a family of proteins to regulate cardiovascular function
    Susanne B Schwedler
    Division of Nephrology, Department of Medicine, University of Wurzburg, Germany
    Am J Kidney Dis 47:212-22. 2006
    ....
  16. ncbi request reprint Vasopeptidase inhibition normalizes blood pressure and restores endothelial function in renovascular hypertension
    Thomas Quaschning
    Department of Nephrology, University Hospital of Freiburg, Freiburg, Germany
    Kidney Blood Press Res 29:351-9. 2006
    ..The present study investigated the effect of the vasopeptidase inhibitor AVE7688 in comparison to the ACE inhibitor ramipril on systolic blood pressure (SBP) and endothelial function in renovascular hypertension...
  17. ncbi request reprint Has the time come to use antioxidant therapy in uraemic patients?
    Jan Galle
    Medizinische Klinik, Schwerpunkt Nephrologie, Universitat Wurzburg, Germany
    Nephrol Dial Transplant 18:1452-5. 2003
  18. ncbi request reprint Phosphorylation of blood vessel vasodilator-stimulated phosphoprotein at serine 239 as a functional biochemical marker of endothelial nitric oxide/cyclic GMP signaling
    César Ibarra-Alvarado
    Rudolf Buchheim Institute for Pharmacology, Justus Liebig University, Giessen, Germany
    Mol Pharmacol 61:312-9. 2002
    ..These data suggest that vascular P(Ser239)-VASP is primarily regulated by the NO/cGMP pathway and may thus serve as a biochemical marker for the activity state of this essential pathway in endothelial function...