Yasuyuki Fujita

Summary

Country: Germany

Publications

  1. ncbi request reprint Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
    Yasuyuki Fujita
    Max Delbruck Center for Molecular Medicine, Robert Rossle Str 10, 13125 Berlin, Germany
    Nat Cell Biol 4:222-31. 2002
  2. pmc Rap1 regulates the formation of E-cadherin-based cell-cell contacts
    Catherine Hogan
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, Gower Street, London WC1E 6BT, United Kingdom
    Mol Cell Biol 24:6690-700. 2004
  3. pmc The transcriptional repressor Glis2 is a novel binding partner for p120 catenin
    Catherine Rose Hosking
    Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, Department of Biology, University College London, London WC1E 6BT, UK
    Mol Biol Cell 18:1918-27. 2007
  4. pmc Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts
    Sophie Dupre-Crochet
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, and Department of Biology, University College London, Gower Street, London, United Kingdom
    Mol Cell Biol 27:3804-16. 2007
  5. ncbi request reprint beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
    Dietmar Zechner
    Max Delbrück Center of Molecular Medicine, Robert Rossle Str 10, 13125, Berlin, Germany
    Dev Biol 258:406-18. 2003
  6. pmc A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus
    Emma C Ferber
    University College London, London, WC1E 6BT, UK
    J Biol Chem 283:12691-700. 2008
  7. pmc Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions
    Felipe Palacios
    Department of Biological Sciences, University of Notre Dame, Box 369, Galvin Life Sciences Bldg, Notre Dame, IN 46556 0369, USA
    Mol Cell Biol 25:389-402. 2005
  8. ncbi request reprint Epithelial cell shape and Rho small GTPases
    Yasuyuki Fujita
    MRC Laboratory for Cell and Molecular Biology, Cell Biology Unit and Department of Biology, University College London, UK
    Novartis Found Symp 269:144-55; discussion 155-8, 223-30. 2005
  9. ncbi request reprint CTACK/CCL27 accelerates skin regeneration via accumulation of bone marrow-derived keratinocytes
    Daisuke Inokuma
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Stem Cells 24:2810-6. 2006
  10. ncbi request reprint A novel interaction between kinesin and p120 modulates p120 localization and function
    Masahiro Yanagisawa
    Mayo Clinic Cancer Center, Jacksonville, Florida 32224, USA
    J Biol Chem 279:9512-21. 2004

Collaborators

  • Walter Birchmeier
  • Jürgen Behrens
  • Martin Scheffner
  • Carmen Birchmeier
  • Albert B Reynolds
  • V Braga
  • Panos Z Anastasiadis
  • Emma C Ferber
  • Catherine Hogan
  • Catherine Rose Hosking
  • Sophie Dupre-Crochet
  • Carl U Bialucha
  • Angélica Figueroa
  • Daisuke Inokuma
  • Carl Uli Bialucha
  • Felipe Palacios
  • Masahiro Yanagisawa
  • Dietmar Zechner
  • Juliet Daniel
  • Carien Niessen
  • Hiroyoshi Ariga
  • Mihoko Kajita
  • Anthony Wadlow
  • Lara Tobiansky
  • Fausto Ulloa
  • Sew Y Peak-Chew
  • Kris Gevaert
  • Franck Pichaud
  • Joanna Adams
  • James Briscoe
  • Emily C N Richardson
  • Tadamichi Shimizu
  • Riichiro Abe
  • Hideki Nakamura
  • James R McMillan
  • Hiroshi Shimizu
  • Akihiko Shibaki
  • Mikako Sasaki
  • Jogender S Tushir
  • CRISLYN D'SOUZA-SCHOREY
  • Patricia Cogram
  • Aixia Wang
  • Norberto Serpente
  • Stephan Michael Feller
  • Irina N Kaverina
  • Jörg Hülsken
  • Thomas Muller
  • E Bryan Crenshaw
  • Makoto M Taketo
  • Ingrid Walther

Detail Information

Publications12

  1. ncbi request reprint Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
    Yasuyuki Fujita
    Max Delbruck Center for Molecular Medicine, Robert Rossle Str 10, 13125 Berlin, Germany
    Nat Cell Biol 4:222-31. 2002
    ..Through dynamic recycling of E-cadherin, Hakai can thus modulate cell adhesion, and could participate in the regulation of epithelial--mesenchymal transitions in development or metastasis...
  2. pmc Rap1 regulates the formation of E-cadherin-based cell-cell contacts
    Catherine Hogan
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, Gower Street, London WC1E 6BT, United Kingdom
    Mol Cell Biol 24:6690-700. 2004
    ..Furthermore, our data suggest that Cdc42 functions downstream of Rap1 in this process. We conclude that Rap1 plays a vital role in the establishment of E-cadherin-based cell-cell adhesion...
  3. pmc The transcriptional repressor Glis2 is a novel binding partner for p120 catenin
    Catherine Rose Hosking
    Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, Department of Biology, University College London, London WC1E 6BT, UK
    Mol Biol Cell 18:1918-27. 2007
    ..These data indicate that p120 has additional novel functions in the nucleus together with Glis2...
  4. pmc Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts
    Sophie Dupre-Crochet
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, and Department of Biology, University College London, Gower Street, London, United Kingdom
    Mol Cell Biol 27:3804-16. 2007
    ..These data indicate that CK1 is a novel negative regulator of cadherin-based cell-cell contacts...
  5. ncbi request reprint beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
    Dietmar Zechner
    Max Delbrück Center of Molecular Medicine, Robert Rossle Str 10, 13125, Berlin, Germany
    Dev Biol 258:406-18. 2003
    ..beta-Catenin signals are thus essential for the maintenance of proliferation of neuronal progenitors, controlling the size of the progenitor pool, and impinging on the decision of neuronal progenitors to proliferate or to differentiate...
  6. pmc A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus
    Emma C Ferber
    University College London, London, WC1E 6BT, UK
    J Biol Chem 283:12691-700. 2008
    ..Finally, we show that E-cad/CTF2 can regulate the p120-Kaiso-mediated signaling pathway in the nucleus. These data indicate a novel role for cleaved E-cadherin in the nucleus...
  7. pmc Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions
    Felipe Palacios
    Department of Biological Sciences, University of Notre Dame, Box 369, Galvin Life Sciences Bldg, Notre Dame, IN 46556 0369, USA
    Mol Cell Biol 25:389-402. 2005
    ..Our studies reveal that the lysosomal targeting of E-cadherin is an important posttranscriptional mechanism to deplete cellular E-cadherin during Src-induced epithelial to mesenchymal transitions...
  8. ncbi request reprint Epithelial cell shape and Rho small GTPases
    Yasuyuki Fujita
    MRC Laboratory for Cell and Molecular Biology, Cell Biology Unit and Department of Biology, University College London, UK
    Novartis Found Symp 269:144-55; discussion 155-8, 223-30. 2005
    ....
  9. ncbi request reprint CTACK/CCL27 accelerates skin regeneration via accumulation of bone marrow-derived keratinocytes
    Daisuke Inokuma
    Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Stem Cells 24:2810-6. 2006
    ....
  10. ncbi request reprint A novel interaction between kinesin and p120 modulates p120 localization and function
    Masahiro Yanagisawa
    Mayo Clinic Cancer Center, Jacksonville, Florida 32224, USA
    J Biol Chem 279:9512-21. 2004
    ..Taken together, the data suggest that kinesin affects both the targeting and activity of p120 at several cellular locations...
  11. pmc p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase Czeta and regulates cell polarity
    Carl U Bialucha
    Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, England, UK
    J Cell Biol 178:575-81. 2007
    ..p32 knockdown by short hairpin RNA also induces cell polarity defects. Collectively, our data indicate that p32 is a novel regulator of cell polarity that forms a complex with mLgl2 and aPKC and enhances aPKC activity...
  12. ncbi request reprint Regulation of cell-cell adhesion by Rap1
    Yasuyuki Fujita
    MRC Laboratory for Molecular and Cell Biology, Cell Biology Unit and Department of Biology, University College, London, United Kingdom
    Methods Enzymol 407:359-72. 2006
    ..This is important, because different receptors that accumulate at sites of cell-cell contacts are also able to activate Rap1 (Fukuyama et al., 2005; Mandell et al., 2005)...