Research Topics
Species | M FroschSummaryCountry: Germany Publications
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Detail Information
Publications
New insights in systemic juvenile idiopathic arthritis--from pathophysiology to treatmentM Frosch
University of Muenster, Department of Paediatrics, Albert Schweitzer Str 33, D 48149 Muenster, Germany
Rheumatology (Oxford) 47:121-5. 2008..First case studies show improvement and remission on therapy in a substantial portion of these patients. In this review, we summarize the current knowledge of pathophysiology and experiences in the treatment of SJIA...
Wegener granulomatosis in childhood and adolescenceMichael Frosch
Department of Paediatrics, University of Munster, Albert Schweitzer Strasse 33, Munster, Germany
Eur J Pediatr 163:425-34. 2004....
Arthrosonography of hip and knee joints in the follow up of juvenile rheumatoid arthritisM Frosch
Department of Paediatrics, University of Muenster, Albert Schweitzer Str 33, D 48149 Muenster, Germany
Ann Rheum Dis 62:242-4. 2003..To evaluate sensitivity of arthrosonography of hip and knee joints for monitoring disease activity in juvenile rheumatoid arthritis (JRA)...
Periventricular cystic lesions in a preterm infant after a car accident during pregnancyH Rabe
Department of Pediatrics, University Hospital of Munster, Albert Schweitzer Strasse 33, D 48129 Munster, Germany
Eur J Ultrasound 14:171-8. 2001..The literature on car accidents during pregnancy is reviewed with specific focus on neonatal neurological outcome...
Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop?D Foell
Department of Paediatrics, University of Muenster, Albert Schweitzer Str 33, D 48149 Muenster, Germany
Ann Rheum Dis 63:206-8. 2004....
Autologous peripheral blood stem cell transplantation and anti-B-cell directed immunotherapy for refractory auto-immune haemolytic anaemiaS Seeliger
Department of Paediatrics, , Germany
Eur J Pediatr 160:492-6. 2001....
Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritisHelmut Wittkowski
Interdisciplinary Centre of Clinical Research, University of Munster, Röntgenstr 21, D 48149 Munster, Germany
Ann Rheum Dis 66:1020-5. 2007..The aim of this project was to analyse the effect of intra-articular corticosteroids or systemic anti-TNF treatment on synovial expression and serum levels of S100A12 in rheumatoid arthritis (RA)...
Systemic juvenile rheumatoid arthritis: cognitive function and social adjustmentReinhold Feldmann
Department of Pediatrics, University Hospital of Munster, Munster, Germany
Ann Neurol 58:605-9. 2005..Cognitive performance and social adjustment of young patients with SJRA are not affected by disease activity and duration...
Early activation of cutaneous vessels and epithelial cells is characteristic of acute systemic onset juvenile idiopathic arthritisMichael Frosch
Institute of Experimental Dermatology, , Germany
Exp Dermatol 14:259-65. 2005..Their differential expression further points to distinct roles of the individual molecules in inflammatory processes...
Early detection of severe cholestatic hepatopathy in COACH syndromeDirk Foell
Department of Pediatrics, University Hospital Munster, Germany
Am J Med Genet 111:429-34. 2002..Progressive destructive cholangiopathy may contribute to hepatic fibrosis in COACH syndrome. Liver disease can be severe even in cases with mild neurologic deficits...
Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammationDirk Foell
Department of Pediatrics, University of Munster, Munster, Germany
Clin Chim Acta 344:37-51. 2004..In this review, pro-inflammatory functions of S100 proteins and their usefulness as biomarkers of inflammation are presented...
Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrationsDirk Foell
Institute of Experimental Dermatology and Department of Pediatrics, University of Muenster, Muenster, Germany
Arthritis Rheum 50:1286-95. 2004..The aim of our study was to determine neutrophil activation in juvenile rheumatoid arthritis (JRA) by analyzing S100A12 (EN-RAGE; calgranulin C), a proinflammatory protein secreted by human neutrophils...
Increased perivascular synovial membrane expression of myeloid-related proteins in psoriatic arthritisDavid Kane
Department of Rheumatology, St Vincent's University Hospital, Dublin, Ireland
Arthritis Rheum 48:1676-85. 2003..Moreover, MRP expression is reduced following MTX treatment. MRP proteins may represent a novel therapeutic target in inflammatory arthritis...
Expression of MRP8 and MRP14 by macrophages is a marker for severe forms of glomerulonephritisMichael Frosch
Institute of Experimental Dermatology, University of Munster, Röntgenstr 21, D 48149, Munster, Germany
J Leukoc Biol 75:198-206. 2004..In addition, our findings reflect differences in the inflammatory mechanisms underlying the various forms of GN, as they revealed that distinct macrophage subpopulations prevail in the different forms of GN...
Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritisMichael Frosch
Institute of Experimental Dermatology and Department of Pediatrics, University of Munster, Munster, Germany
Arthritis Rheum 48:2622-6. 2003....
