Peter Fritz

Summary

Country: Germany

Publications

  1. pmc Smad4-expression is decreased in breast cancer tissues: a retrospective study
    Christina H Stuelten
    Department of Clinical Chemistry, Robert Bosch Hospital, Stuttgart, Germany
    BMC Cancer 6:25. 2006
  2. pmc c-erbB2 and topoisomerase IIalpha protein expression independently predict poor survival in primary human breast cancer: a retrospective study
    Peter Fritz
    Department of Diagnostic Medicine, Pathology, Robert Bosch Hospital, Stuttgart, Germany
    Breast Cancer Res 7:R374-84. 2005
  3. doi request reprint Involvement of α-klotho, fibroblast growth factor-, vitamin-D- and calcium-sensing receptor in 53 patients with primary hyperparathyroidism
    Joerg Latus
    Department of Internal Medicine, Division of Nephrology, Robert Bosch Hospital, Auerbachstrasse 110, 70376, Stuttgart, Germany
    Endocrine 44:255-63. 2013
  4. pmc Phenotypes of encapsulating peritoneal sclerosis--macroscopic appearance, histologic findings, and outcome
    Joerg Latus
    Department of Internal Medicine, 1 Division of Nephrology, Robert Bosch Hospital, and Department of General, Visceral and Trauma Surgery, 2 Robert Bosch Hospital, Stuttgart, Germany
    Perit Dial Int 33:495-502. 2013
  5. pmc The spectrum of podoplanin expression in encapsulating peritoneal sclerosis
    Niko Braun
    Department of Internal Medicine, Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    PLoS ONE 7:e53382. 2012
  6. pmc Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast
    Maike Sonnenberg
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology and University of Tuebingen, Stuttgart, Germany
    BMC Cancer 8:364. 2008
  7. ncbi request reprint A polymorphism in the TC21 promoter associates with an unfavorable tamoxifen treatment outcome in breast cancer
    Matjaz Rokavec
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology and Department of Gynecology, Robert Bosch Hospital, Stuttgart, Germany
    Cancer Res 68:9799-808. 2008
  8. ncbi request reprint Antiestrogens suppress effects of transforming growth factor-β in breast cancer cells via the signaling axis estrogen receptor-α and Y-box Binding Protein-1
    Simone L Popp
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    Anticancer Res 33:2473-80. 2013
  9. pmc Periostin: a matricellular protein involved in peritoneal injury during peritoneal dialysis
    Niko Braun
    Department of Internal Medicine, 1 Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, and Institute of Digital Medicine, 2 Stuttgart, Germany
    Perit Dial Int 33:515-28. 2013
  10. doi request reprint Analysis of α-klotho, fibroblast growth factor-, vitamin-D and calcium-sensing receptor in 70 patients with secondary hyperparathyroidism
    Joerg Latus
    Department of Internal Medicine, Division of Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    Kidney Blood Press Res 37:84-94. 2013

Collaborators

Detail Information

Publications53

  1. pmc Smad4-expression is decreased in breast cancer tissues: a retrospective study
    Christina H Stuelten
    Department of Clinical Chemistry, Robert Bosch Hospital, Stuttgart, Germany
    BMC Cancer 6:25. 2006
    ..Since tumors often display altered TGF-beta signaling, particularly involving the Smad-pathway, we investigated the role of Smad4-expression in breast cancer...
  2. pmc c-erbB2 and topoisomerase IIalpha protein expression independently predict poor survival in primary human breast cancer: a retrospective study
    Peter Fritz
    Department of Diagnostic Medicine, Pathology, Robert Bosch Hospital, Stuttgart, Germany
    Breast Cancer Res 7:R374-84. 2005
    ..The aim of the study was to analyze retrospectively whether the expression of c-erbB2 and topoisomerase IIalpha protein influences the long-term outcome of patients with primary breast cancer...
  3. doi request reprint Involvement of α-klotho, fibroblast growth factor-, vitamin-D- and calcium-sensing receptor in 53 patients with primary hyperparathyroidism
    Joerg Latus
    Department of Internal Medicine, Division of Nephrology, Robert Bosch Hospital, Auerbachstrasse 110, 70376, Stuttgart, Germany
    Endocrine 44:255-63. 2013
    ..Whether these findings give new insights into the pathogenesis of the disease is yet unknown and has to be elucidated...
  4. pmc Phenotypes of encapsulating peritoneal sclerosis--macroscopic appearance, histologic findings, and outcome
    Joerg Latus
    Department of Internal Medicine, 1 Division of Nephrology, Robert Bosch Hospital, and Department of General, Visceral and Trauma Surgery, 2 Robert Bosch Hospital, Stuttgart, Germany
    Perit Dial Int 33:495-502. 2013
    ..Encapsulating peritoneal sclerosis (EPS) is a rare but devastating complication of peritoneal dialysis (PD), with clinical signs of abdominal pain, bowel obstruction, and weight loss in late stages...
  5. pmc The spectrum of podoplanin expression in encapsulating peritoneal sclerosis
    Niko Braun
    Department of Internal Medicine, Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    PLoS ONE 7:e53382. 2012
    ..Podoplanin might serve as a useful adjunct to the morphological workup of peritoneal biopsies...
  6. pmc Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast
    Maike Sonnenberg
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology and University of Tuebingen, Stuttgart, Germany
    BMC Cancer 8:364. 2008
    ..This study was undertaken to analyze the influence of chemotherapy on carcinoma-associated fibroblasts (CAFs) in vitro and in vivo...
  7. ncbi request reprint A polymorphism in the TC21 promoter associates with an unfavorable tamoxifen treatment outcome in breast cancer
    Matjaz Rokavec
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology and Department of Gynecology, Robert Bosch Hospital, Stuttgart, Germany
    Cancer Res 68:9799-808. 2008
    ..35; 95% CI, 1.34-4.14). Our functional and patient-based results suggest that the TC21 -582C>T polymorphism improves prediction of tamoxifen treatment outcome in breast cancer...
  8. ncbi request reprint Antiestrogens suppress effects of transforming growth factor-β in breast cancer cells via the signaling axis estrogen receptor-α and Y-box Binding Protein-1
    Simone L Popp
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    Anticancer Res 33:2473-80. 2013
    ..Thus, a putative influence of YB1 on TGFβ signaling should be investigated...
  9. pmc Periostin: a matricellular protein involved in peritoneal injury during peritoneal dialysis
    Niko Braun
    Department of Internal Medicine, 1 Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, and Institute of Digital Medicine, 2 Stuttgart, Germany
    Perit Dial Int 33:515-28. 2013
    ..We hypothesized that this protein might be expressed in the peritoneal cavity of patients on peritoneal dialysis (PD) and even more in patients with signs of encapsulating peritoneal sclerosis (EPS)...
  10. doi request reprint Analysis of α-klotho, fibroblast growth factor-, vitamin-D and calcium-sensing receptor in 70 patients with secondary hyperparathyroidism
    Joerg Latus
    Department of Internal Medicine, Division of Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    Kidney Blood Press Res 37:84-94. 2013
    ....
  11. pmc Histological criteria for encapsulating peritoneal sclerosis - a standardized approach
    Niko Braun
    Department of Internal Medicine, Division of Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    PLoS ONE 7:e48647. 2012
    ..Two blinded investigators analyzed 20 histological characteristics in EPS and PD patients...
  12. ncbi request reprint The promoter C specific ERalpha isoform is associated with tamoxifen outcome in breast cancer
    Sandra Amaral
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart and University Tuebingen, Auerbachstrasse 112, 70376, Stuttgart, Germany
    Breast Cancer Res Treat 118:323-31. 2009
    ..41; CI 95% 1.45-8.04). The ESR1_C isoform had a prolonged mRNA half-life and a more relaxed 5'-UTR structure compared to ESR1_A isoform. ESR1_C levels may aid in the discrimination of patients' endocrine responsiveness...
  13. ncbi request reprint Gastrointestinal involvement in granulomatosis with polyangiitis and microscopic polyangiitis: histological features and outcome
    Joerg Latus
    Division of Nephrology, Department of Internal Medicine, Robert Bosch Hospital, Stuttgart, Germany
    Int J Rheum Dis 17:412-9. 2014
    ..Gastrointestinal (GI) involvement in patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) is rare...
  14. doi request reprint Encapsulating peritoneal sclerosis: a rare, serious but potentially curable complication of peritoneal dialysis-experience of a referral centre in Germany
    Joerg Latus
    Department of Internal Medicine, Division of Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    Nephrol Dial Transplant 28:1021-30. 2013
    ..Chronic peritoneal dialysis (PD) can be complicated by encapsulating peritoneal sclerosis (EPS), the most severe complication associated with long-term PD...
  15. doi request reprint Increased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatment
    Reiner Hoppe
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany University Tuebingen, Tuebingen, Germany
    Eur J Cancer 49:3598-608. 2013
    ..MicroRNAs have been suggested to be important prognosticators in breast cancer. This study aims to identify microRNAs with the potential to predict tamoxifen response...
  16. doi request reprint Olfactomedin-4 is a glycoprotein secreted into mucus in active IBD
    Michael Gersemann
    Department of Internal Medicine I, Robert Bosch Hospital, Stuttgart, Germany
    J Crohns Colitis 6:425-34. 2012
    ..Olfactomedin-4 (OLFM4) is a glycoprotein characteristic of intestinal stem cells and apparently involved in mucosal defense of the stomach and colon. Here we studied its expression, regulation and function in IBD...
  17. doi request reprint TKTL-1 expression in lung cancer
    Peter Fritz
    Department of Clinical Pathology, Robert Bosch Hospital, Stuttgart, Germany
    Pathol Res Pract 208:203-9. 2012
    ..Based on this data, we conclude that TKTL1 could be a target protein for improved therapeutic strategies in some cases of lung cancer...
  18. doi request reprint Microsomal epoxide hydrolase expression in the endometrial uterine corpus is regulated by progesterone during the menstrual cycle
    Simone L Popp
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    J Mol Histol 41:111-9. 2010
    ..In contrast our results suggest that MPA had no influence on the mEH protein level in the ERalpha- IKPRAB-36 cells. In conclusion, mEH expression is regulated by progesterone in the presence of both PRs and ERalpha...
  19. ncbi request reprint Polymorphism of the DNA repair enzyme XRCC1 is associated with treatment prediction in anthracycline and cyclophosphamide/methotrexate/5-fluorouracil-based chemotherapy of patients with primary invasive breast cancer
    Malgorzata Jaremko
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, University of Tubingen, Stuttgart, Germany
    Pharmacogenet Genomics 17:529-38. 2007
    ..Therefore, we tested the hypothesis of a relationship between event-free survival and genotype distributions of seven polymorphic DNA repair enzymes and four cell cycle regulators...
  20. ncbi request reprint Tubular Breast Cancer. A Retrospective study
    Peter Fritz
    Institute of Digital Medicine, Stuttgart, Germany Robert Bosch Hospital, Department of Clinical Pathology, Stuttgart, Germany
    Anticancer Res 34:3647-56. 2014
    ..025). Our data suggest that post-operative radiotherapy is an important treatment to prolong survival for patients suffering from tubular breast cancer. ..
  21. pmc Short term culture of breast cancer tissues to study the activity of the anticancer drug taxol in an intact tumor environment
    Heiko van der Kuip
    Dr, Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    BMC Cancer 6:86. 2006
    ..To study drug-sensitivity within different compartments of an individual tumor ex vivo, culture models directly established from fresh tumor tissues are absolutely essential...
  22. doi request reprint Difference in the expression of hormone receptors and fibrotic markers in the human peritoneum--implications for therapeutic targets to prevent encapsulating peritoneal sclerosis
    Niko Braun
    Division of General Internal Medicine and Nephrology, Department of Internal Medicine, Robert Bosch Hospital, Stuttgart, Germany
    Perit Dial Int 31:291-300. 2011
    ..We also investigated estrogen receptor (ER), matrix metalloproteinase 9 (MMP9), and transforming growth factor β1 (TGFβ1) in the context of their potential role in tamoxifen therapy...
  23. pmc Estrogen-mediated downregulation of CD24 in breast cancer cells
    Benny Abraham Kaipparettu
    Division of Molecular Mechanisms of Origin and Treatment of Breast Cancer, Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    Int J Cancer 123:66-72. 2008
    ..Together, our results show that CD24 is repressed by estrogen and that this repression is a direct transcriptional effect depending on ER alpha and histone deacetylases...
  24. ncbi request reprint Predictors for treatment success and expression of glucocorticoid receptor in giant cell arteritis and polymyalgia rheumatica
    Niko Braun
    Division of General Internal Medicine and Nephrology, Department of Internal Medicine, Robert Bosch Hospital Stuttgart, 70376 Stuttgart, Germany
    J Rheumatol 36:2269-76. 2009
    ....
  25. ncbi request reprint The expression patterns of peritoneal defensins
    Alexander Grupp
    Division of General Internal Medicine and Nephrology, Department of Internal Medicine, Robert Bosch Krankenhaus, Auerbachstrasse 110, Stuttgart, Germany
    Perit Dial Int 27:654-62. 2007
    ..Local defense mechanisms are important for the integrity of the peritoneum, but few details are known about the expression patterns of antimicrobial proteins such as human defensin in normal and damaged peritoneum...
  26. ncbi request reprint Metallothionein and dendritic cells in skin of end-stage renal disease patients not on dialysis, or on hemodialysis or peritoneal dialysis
    Dominik M Alscher
    Department of Internal Medicine, Robert Bosch Krankenhaus, Stuttgart, Germany
    Perit Dial Int 22:449-53. 2002
    ..The pathogenesis of these defects and derangements are poorly understood; therefore, we studied immune competent cells, dermal dendrocytes (DC), and a special proinflammatory protein, metallothionein (MT), in the skin of these patients...
  27. ncbi request reprint Cardiovascular magnetic resonance assessment of human myocarditis: a comparison to histology and molecular pathology
    Heiko Mahrholdt
    Division of Cardiology, Robert Bosch Medical Center, Stuttgart, Germany
    Circulation 109:1250-8. 2004
    ..Because the initial onset is difficult to recognize clinically and the diagnostic tools available are unsatisfactory, new strategies to diagnose myocarditis are needed...
  28. ncbi request reprint Metallothionein in liver-biopsies from patients with different diseases
    Dominik Mark Alscher
    Division of General Internal Medicine and Nephrology, Department of Internal Medicine, Robert Bosch Hospital, Stuttgart, Germany
    Exp Toxicol Pathol 54:245-53. 2002
    ..This could help in identifying these conditions in liver biopsies...
  29. ncbi request reprint Apoptosis of mesothelial cells caused by unphysiological characteristics of peritoneal dialysis fluids
    Dominik M Alscher
    Division of General Internal Medicine and Nephrology, Department of Internal Medicine, Robert Bosch Hospital, Stuttgart, Germany
    Artif Organs 27:1035-40. 2003
    ..In conclusion, after improving PDFs and introducing neutral fluids, further attention should be drawn to inducers of apoptosis. Apoptosis can be detected quite early (24 h) and is caused by plasticizers and high osmolarity...
  30. ncbi request reprint Presentation, patterns of myocardial damage, and clinical course of viral myocarditis
    Heiko Mahrholdt
    Division of Cardiology, Robert Bosch Medical Center, Auerbachstrasse 110, 70376 Stuttgart, Germany
    Circulation 114:1581-90. 2006
    ..Enteroviruses and adenoviruses have been considered the most common causes of viral myocarditis, but parvovirus B19 (PVB19) and human herpesvirus 6 (HHV6) are increasingly found in endomyocardial biopsy samples...
  31. ncbi request reprint Induction of metallothionein in mesothelial cells by zinc
    Dominik M Alscher
    Division of General Internal Medicine and Nephrology, Department of Internal Medicine, Stuttgart, Germany
    Artif Organs 31:488-91. 2007
    ..Zinc was able to upregulate MT significantly in HPMC and MTC on the RNA and protein level. Fourfold increases of MT were achievable...
  32. ncbi request reprint Peritoneal mast cells in peritoneal dialysis patients, particularly in encapsulating peritoneal sclerosis patients
    Dominik M Alscher
    Department of Internal Medicine, Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    Am J Kidney Dis 49:452-61. 2007
    ..Therefore, we investigated mast cells in different pathological conditions of the peritoneum...
  33. doi request reprint Detection of rearrangements and transcriptional up-regulation of ALK in FFPE lung cancer specimens using a novel, sensitive, quantitative reverse transcription polymerase chain reaction assay
    Kim Gruber
    Department of Clinical Pathology, Robert Bosch Krankenhaus, Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, Germany Institute of Pathology, University of Wurzburg, Wurzburg, Germany Center for Pulmonology and Thoracic Surgery, Klinik Schillerhöhe, Stuttgart Gerlingen, Germany and Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, and Department of Clinical Pharmacology, University Hospital, Tubingen, Germany
    J Thorac Oncol 9:307-15. 2014
    ..We devised a sensitive and robust routine diagnostic test for the detection of rearrangements and transcriptional up-regulation of ALK...
  34. ncbi request reprint A novel functional polymorphism in the transforming growth factor-beta2 gene promoter and tumor progression in breast cancer
    Julia Beisner
    Department of Clinical Chemistry, Robert Bosch Hospital, Auerbachstrasse 110, 70376 Stuttgart, Germany
    Cancer Res 66:7554-61. 2006
    ..18; 95% confidence interval, 1.44-18.62). We provide evidence that the TGFB2 -246ins polymorphism leads to enhanced TGF-beta(2) expression levels in vivo and might thereby contribute to tumor progression and development of metastases...
  35. ncbi request reprint Induction of metallothionein in proximal tubular cells by zinc and its potential as an endogenous antioxidant
    Dominik M Alscher
    Division of General Internal Medicine and Nephrology, Department of Internal Medicine, Robert Bosch Krankenhaus, Stuttgart, Germany
    Kidney Blood Press Res 28:127-33. 2005
    ....
  36. doi request reprint Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis
    Michael Gersemann
    Department of Internal Medicine I, Robert Bosch Hospital, Stuttgart, Germany
    Differentiation 77:84-94. 2009
    ..Conspicuously, inflammation is associated with an enhanced goblet cell differentiation in CD but not in UC, a defect possibly of pathogenic importance...
  37. doi request reprint Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis
    Niko Braun
    Department of Internal Medicine, Division of General Internal Medicine and Nephrology, Robert Bosch Hospital, Stuttgart, Germany
    Nephrol Dial Transplant 26:1033-41. 2011
    ..Podoplanin is expressed by mesothelial cells and lymphatic vessels, which are involved in inflammatory reactions in the peritoneal cavity...
  38. ncbi request reprint Herpes simplex virus colitis complicating ulcerative colitis: A case report and brief review on superinfections
    Marco Oliver Schunter
    Department of Gastroenterology and Hepatology, Robert Bosch Hospital, Auerbachstrasse 110, 70376 Stuttgart, Germany
    J Crohns Colitis 1:41-6. 2007
    ..Herpes simplex virus colitis is a rare but potentially fatal complication of immunosuppressive treatment in patients with inflammatory bowel disease. Prompt diagnosis and efficient antiviral therapy are mandatory to improve prognosis...
  39. ncbi request reprint Attenuated induction of epithelial and leukocyte serine antiproteases elafin and secretory leukocyte protease inhibitor in Crohn's disease
    Michael Schmid
    Department of Internal Medicine I, Robert Bosch Hospital, Auerbachstr 112, 70376 Stuttgart, and Department of Dermatology, University of Kiel, Germany
    J Leukoc Biol 81:907-15. 2007
    ..This could contribute to the transmural depth of tissue destruction in CD. Elafin and SLPI may be added to the list of defensin-like peptides with diminished induction in CD versus UC...
  40. ncbi request reprint Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers
    Ina Bergheim
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    J Lipid Res 47:42-50. 2006
    ..In conclusion, in normal weight female gallstone carriers, the decreased expression of ileal bile acid transporters may form a molecular basis for gallstone formation...
  41. ncbi request reprint Influence of omeprazole on multidrug resistance protein 3 expression in human liver
    Monika Hitzl
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    J Pharmacol Exp Ther 304:524-30. 2003
    ..05), in HepG2 cells treated with omeprazole. Finally, MRP3 was induced in HepG2 cells by beta-naphthoflavone. In summary, treatment with omeprazole and beta-naphthoflavone is a determinant of variable human hepatic MRP3 expression...
  42. ncbi request reprint MALDI-TOF MS and TaqMan assisted SNP genotyping of DNA isolated from formalin-fixed and paraffin-embedded tissues (FFPET)
    Malgorzata Jaremko
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
    Hum Mutat 25:232-8. 2005
    ..Our study shows for the first time that MALDI-TOF MS and TaqMan genotyping procedures provide reliable data, and are therefore applicable in studies that require large scale FFPET genotyping...
  43. ncbi request reprint Transbronchial cryobiopsy: a new tool for lung biopsies
    Alexander Babiak
    Department of Pulmonary Medicine, Red Cross Medical Center, Stuttgart, Germany
    Respiration 78:203-8. 2009
    ..Flexible cryoprobes have been shown to be useful in therapeutic bronchoscopy. We introduce a novel technique for obtaining lung biopsies bronchoscopically, using a flexible cryoprobe...
  44. ncbi request reprint Prognostic significance of transforming growth factor beta receptor II in estrogen receptor-negative breast cancer patients
    Miriam B Buck
    Robert Bosch Hospital, Department of Clinical Chemistry, Stuttgart, Germany
    Clin Cancer Res 10:491-8. 2004
    ..This study was conducted to further analyze the role of TGF-beta receptors in breast cancer and to evaluate their significance as prognostic markers...
  45. ncbi request reprint [Concurrent chemotherapy and radiation therapy for unresectable locally advanced carcinoma of the esophagus. Phase II study and clinical review on literature]
    Peter Fritz
    Abteilung Klinische Radiologie, Schwerpunkt Strahlentherapie und Poliklinik, Universitat Heidelberg
    Strahlenther Onkol 179:328-36. 2003
    ..The results of combining: first surgery, then radiation therapy, which have been unsatisfactory for decades, encourage therapeutic concepts involving a variety of modalities...
  46. ncbi request reprint 5-year results of pulsed dose rate brachytherapy applied as a boost after breast-conserving therapy in patients at high risk for local recurrence from breast cancer
    Wolfgang Harms
    Department of Clinical Radiology, Radiation Therapy, University of Heidelberg, Germany
    Strahlenther Onkol 178:607-14. 2002
    ..The aim of this study was to evaluate effect, toxicity, and cosmesis of a prospectively applied pulsed dose rate (PDR) brachytherapy boost schedule in patients with stage I/II/IIIa invasive breast cancer...
  47. ncbi request reprint Telomerase activity in chronic inflammatory bowel disease
    Elke Kleideiter
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Auerbachstr 112, D 70376 Stuttgart, Germany
    Dig Dis Sci 48:2328-32. 2003
    ....
  48. ncbi request reprint Impact of mistletoe lectin binding in breast cancer
    Peter Fritz
    Zentrum für diagnostische Medizin Robert Bosch Krankenhaus, Auerbachstr 110, D 70376 Stuttgart, Germany
    Anticancer Res 24:1187-92. 2004
    ..The aim of this study was to determine the correlation between VAA-1 binding in breast cancer and disease outcome...
  49. ncbi request reprint Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis
    Benny K Abraham
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, D 70376 Stuttgart, Germany
    Clin Cancer Res 11:1154-9. 2005
    ..Validation of these findings with respect to detection in clinical samples, prognosis, and clinical relevance is in demand...
  50. ncbi request reprint The enlarging spectrum of desminopathies: new morphological findings, eastward geographic spread, novel exon 3 desmin mutation
    Alexandra Vrabie
    Department of Neuropathology, Johannes Gutenberg University Medical Center, Langenbeckstrasse 1, 55101 Mainz, Germany
    Acta Neuropathol 109:411-7. 2005
    ....
  51. ncbi request reprint Cyclooxygenase-2 expression in human colorectal cancer is unrelated to overall patient survival
    Richard Fux
    Abteilung Klinische Pharmakologie, Institut fur Pharmakologie und Toxikologie, Universitatsklinikum Tubingen, Tubingen, Germany
    Clin Cancer Res 11:4754-60. 2005
    ..However, data about the relation between COX-2 expression and patient survival are inconclusive as yet. Therefore, we studied COX-2 expression in surgery tissue and survival time in a cohort of 747 colorectal cancer patients...
  52. ncbi request reprint Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes
    Werner Schroth
    Dr Margarete Fischer Bosch Institute of Clinical Pharmacology, Auerbachstrasse 112, D 70376 Stuttgart, Germany
    J Clin Oncol 25:5187-93. 2007
    ..We investigated the predictive value of genetic variants of CYP2D6, CYP2C19, and three other cytochrome P450 enzymes for tamoxifen treatment outcome...
  53. ncbi request reprint Growth/adhesion-regulatory tissue lectin galectin-3: stromal presence but not cytoplasmic/nuclear expression in tumor cells as a negative prognostic factor in breast cancer
    Adina Moisa
    Institut für Gerichtliche Medizin der Universität Tübingen, Germany
    Anticancer Res 27:2131-9. 2007
    ..The endogenous lectin galectin-3 can regulate cell adhesion and proliferation in vitro, thus prompting the examination of its clinical relevance in breast cancer...