Daniel Scharlau

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. doi request reprint Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre
    Daniel Scharlau
    Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    Mutat Res 682:39-53. 2009
  2. doi request reprint Modification of an in vitro model simulating the whole digestive process to investigate cellular endpoints of chemoprevention
    Katrin Stein
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, Jena, Germany
    Br J Nutr 105:678-87. 2011
  3. doi request reprint Effects of synbiotic fermentation products on primary chemoprevention in human colon cells
    Katrin Stein
    Department of Nutritional Toxicology, Institute for Nutrition, Biological Pharmaceutical Faculty, Friedrich Schiller University Jena, 07743 Jena, Germany
    J Nutr Biochem 23:777-84. 2012
  4. ncbi request reprint Gut fermentation products of inulin-type fructans modulate the expression of xenobiotic-metabolising enzymes in human colonic tumour cells
    Umang Munjal
    Friedrich Schiller University Jena, Biological Pharmaceutical Faculty, Institute for Nutrition, Department of Nutritional Toxicology, Dornburger Str 24, 07743 Jena, Germany
    Anticancer Res 32:5379-86. 2012
  5. doi request reprint Fermented wheat aleurone enriched with probiotic strains LGG and Bb12 modulates markers of tumor progression in human colon cells
    Anke Borowicki
    Friedrich Schiller University Jena, Institute for Nutrition, Department of Nutritional Toxicology, Jena, Germany
    Nutr Cancer 63:151-60. 2011
  6. ncbi request reprint In vitro fermented nuts exhibit chemopreventive effects in HT29 colon cancer cells
    Stefanie Lux
    Department of Nutritional Toxicology, Institute of Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, Jena, Germany
    Br J Nutr 108:1177-86. 2012
  7. doi request reprint Fermented wheat aleurone induces enzymes involved in detoxification of carcinogens and in antioxidative defence in human colon cells
    Katrin Stein
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    Br J Nutr 104:1101-11. 2010
  8. doi request reprint Fermentation supernatants of wheat ( Triticum aestivum L.) aleurone beneficially modulate cancer progression in human colon cells
    Anke Borowicki
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    J Agric Food Chem 58:2001-7. 2010
  9. doi request reprint Fermented wheat aleurone inhibits growth and induces apoptosis in human HT29 colon adenocarcinoma cells
    Anke Borowicki
    Department of Nutritional Toxicology, Friedrich Schiller University Jena, Institute for Nutrition, Dornburger Strasse 24, 07743 Jena, Germany
    Br J Nutr 103:360-9. 2010
  10. doi request reprint Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis
    Umang Munjal
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    Br J Nutr 102:663-71. 2009

Detail Information

Publications10

  1. doi request reprint Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre
    Daniel Scharlau
    Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    Mutat Res 682:39-53. 2009
    ..Additional animal and human studies are needed to define the exact role of dietary fibre and butyrate in inducing GST activity and reducing the risk of colon cancer...
  2. doi request reprint Modification of an in vitro model simulating the whole digestive process to investigate cellular endpoints of chemoprevention
    Katrin Stein
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, Jena, Germany
    Br J Nutr 105:678-87. 2011
    ..In conclusion, an in vitro digestion model, which can be used to study the effects of foodstuffs on chemoprevention and gut health in colon cells, is introduced and its physiological relevance is demonstrated...
  3. doi request reprint Effects of synbiotic fermentation products on primary chemoprevention in human colon cells
    Katrin Stein
    Department of Nutritional Toxicology, Institute for Nutrition, Biological Pharmaceutical Faculty, Friedrich Schiller University Jena, 07743 Jena, Germany
    J Nutr Biochem 23:777-84. 2012
    ..The observed effects could improve detoxification of xenobiotics and therefore may lower colon cancer risk...
  4. ncbi request reprint Gut fermentation products of inulin-type fructans modulate the expression of xenobiotic-metabolising enzymes in human colonic tumour cells
    Umang Munjal
    Friedrich Schiller University Jena, Biological Pharmaceutical Faculty, Institute for Nutrition, Department of Nutritional Toxicology, Dornburger Str 24, 07743 Jena, Germany
    Anticancer Res 32:5379-86. 2012
    ....
  5. doi request reprint Fermented wheat aleurone enriched with probiotic strains LGG and Bb12 modulates markers of tumor progression in human colon cells
    Anke Borowicki
    Friedrich Schiller University Jena, Institute for Nutrition, Department of Nutritional Toxicology, Jena, Germany
    Nutr Cancer 63:151-60. 2011
    ..In conclusion, fs aleurone(+) modulated markers of cancer prevention, namely inhibition of cell growth and promotion of apoptosis as well as differentiation...
  6. ncbi request reprint In vitro fermented nuts exhibit chemopreventive effects in HT29 colon cancer cells
    Stefanie Lux
    Department of Nutritional Toxicology, Institute of Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, Jena, Germany
    Br J Nutr 108:1177-86. 2012
    ....
  7. doi request reprint Fermented wheat aleurone induces enzymes involved in detoxification of carcinogens and in antioxidative defence in human colon cells
    Katrin Stein
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    Br J Nutr 104:1101-11. 2010
    ..In conclusion, fermented aleurone is able to act on primary prevention by inducing mRNA expression and the activity of enzymes involved in detoxification of carcinogens and antioxidative defence...
  8. doi request reprint Fermentation supernatants of wheat ( Triticum aestivum L.) aleurone beneficially modulate cancer progression in human colon cells
    Anke Borowicki
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    J Agric Food Chem 58:2001-7. 2010
    ..9-22.2-fold). In conclusion, fermented wheat aleurone is able to act as a secondary chemopreventive agent by modulating parameters of cell growth and survival, whereas cells of an early transformation stage are more sensitive...
  9. doi request reprint Fermented wheat aleurone inhibits growth and induces apoptosis in human HT29 colon adenocarcinoma cells
    Anke Borowicki
    Department of Nutritional Toxicology, Friedrich Schiller University Jena, Institute for Nutrition, Dornburger Strasse 24, 07743 Jena, Germany
    Br J Nutr 103:360-9. 2010
    ..Fermented wheat aleurone is able to induce apoptosis and to block cell cycle - two essential markers of secondary chemoprevention...
  10. doi request reprint Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis
    Umang Munjal
    Department of Nutritional Toxicology, Institute for Nutrition, Friedrich Schiller University Jena, Dornburger Strasse 24, 07743 Jena, Germany
    Br J Nutr 102:663-71. 2009
    ..Moreover, since early adenoma cells were found to be more sensitive, this may have important implications for chemoprevention when translated to the in vivo situation, because survival of early transformed cells could be reduced...