Research Topics
| Timm RosburgSummaryAffiliation: Friedrich Schiller University Country: Germany Publications
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Detail Information
Publications
The influence of repetition and famousness on the intracranially recorded temporobasal N200Timm Rosburg
Department of Epileptology, University of Bonn, Bonn, Germany
Behav Neurosci 119:876-83. 2005..They suppose that the recognition of faces becomes observable within the N200 latency range and that the increased N200 latency reflects a feature processing additional to the holistic face processing...
Internal consistency of dipole localizations for the human movement-evoked magnetic field component 1 (MEF 1)T Rosburg
Psychiatric Department, University of Jena, Germany
Neurosci Lett 215:45-8. 1996..The mean spatial deviation between both halves amounted to 3.8 mm. The window-homogeneity was found to be 2 mm deviation/10 ms...
The dipole location shift within the auditory evoked neuromagnetic field components N100m and mismatch negativity (MMNm)T Rosburg
Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
Clin Neurophysiol 115:906-13. 2004..To investigate whether within the latency range of the neuromagnetic mismatch negativity (MMNm) a similar dipole shift can be observed as found in previous studies for the auditory evoked field component N100m...
Effects of tone repetition on auditory evoked neuromagnetic fieldsTimm Rosburg
Department of Psychiatry, Friedrich Schiller University of Jena, Philosophenweg 3, D 07743 Jena, Germany
Clin Neurophysiol 115:898-905. 2004..To investigate the impact of stimulus repetition on neuromagnetic auditory evoked fields (AEF) in the context of permanently varying auditory stimulation and uniform stimulation...
Left parietal lobe activation to auditory mismatch?Timm Rosburg
Department of Psychiatry, Friedrich Schiller University Jena, Jena, Germany
Hum Brain Mapp 21:44-5; discussion 46-8. 2004..Statistical Parametric Mapping of LORETA Using High-Density EEG and Individual MRI: Application to Mismatch Negativities in Schizophrenia. Hum Brain Mapp 2002;17:168-178)...
Left hemispheric dipole locations of the neuromagnetic mismatch negativity to frequency, intensity and duration deviantsTimm Rosburg
Department of Psychiatry, Friedrich Schiller University, Philosophenweg 3, D 07743, Jena, Germany
Brain Res Cogn Brain Res 16:83-90. 2003..This differentiation between sources emphasizes the importance of feature analysis in MMN(m) generation...
Stimulus duration influences the dipole location shift within the auditory evoked field component N100mT Rosburg
Brain Topogr 15:37-41. 2002..Stimulus duration significantly affected the degree of dipole shift in this direction. It was found to be shorter the shorter the stimulus...
Habituation of the auditory evoked field component N100m and its dependence on stimulus durationT Rosburg
Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07740, Jena, Germany
Clin Neurophysiol 113:421-8. 2002..In the current study we investigated the habituation of the neuromagnetic auditory evoked field (AEF) component N100m and its dependence on stimulus duration...
Habituation of the auditory evoked field component N100m in male patients with schizophreniaT Rosburg
Department of Psychiatry, University of Jena, Philosophenweg 3, D 07740, Jena, Germany
J Psychiatr Res 34:245-54. 2000..However, this difference was related to medication with clozapine. Overall, the habituation behaviour of the N100m seems to be undisturbed in schizophrenic patients...
Hemispheric differences in frequency dependent dipole orientation of the human auditory evoked field component N100mT Rosburg
Department of Psychiatry, Jena University, Germany
Neurosci Lett 258:105-8. 1998..The left hemispheric dipoles were orientated on average 10.8 degrees more vertically for the 5000 Hz condition. This result points to interhemispheric differences on the level of sensory processing...
Endophenotype properties of niacin sensitivity as marker of impaired prostaglandin signalling in schizophreniaStefan Smesny
Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743, Jena, Germany
Prostaglandins Leukot Essent Fatty Acids 77:79-85. 2007..Disruption of arachidonic acid pathways and prostaglandin signalling has been implicated in the pathophysiology of schizophrenia...
Cannabinoids influence lipid-arachidonic acid pathways in schizophreniaStefan Smesny
Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
Neuropsychopharmacology 32:2067-73. 2007..Considering pre-existing vulnerability of lipid metabolism in schizophrenia, observed effects of cannabis use support the notion of a gene x environment interaction...
Increased calcium-independent phospholipase A2 activity in first but not in multiepisode chronic schizophreniaStefan Smesny
Department of Psychiatry, Friedrich Schiller University Jena, Jena, USA
Biol Psychiatry 57:399-405. 2005..Previous studies in chronic schizophrenia were less conclusive. To explore whether iPLA2 changes are stage dependent, we investigated serum iPLA2 activity in various stages of schizophrenia...
The influence of age and gender on niacin skin test results - implications for the use as a biochemical marker in schizophreniaStefan Smesny
Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
J Psychiatr Res 38:537-43. 2004..Consideration of gender and age is strongly recommended for further clinical niacin studies...
Metabolic mapping using 2D 31P-MR spectroscopy reveals frontal and thalamic metabolic abnormalities in schizophreniaStefan Smesny
Department of Psychiatry, Friedrich Schiller University Jena, Philosophenweg 3, D 07743 Jena, Germany
Neuroimage 35:729-37. 2007..Results support the notion of disturbed phospholipid turnover in schizophrenia, probably unrelated to prior pharmacological treatment, and associated with increased energy demand...
Effects of lorazepam on the neuromagnetic mismatch negativity (MMNm) and auditory evoked field component N100mTimm Rosburg
Department of Psychiatry, Friedrich Schiller University Jena, Jena, Germany
Neuropsychopharmacology 29:1723-33. 2004..MMN studies on clinical populations have to be controlled for the recording time because of the strong habituation of this component...
Potential use of the topical niacin skin test in early psychosis -- a combined approach using optical reflection spectroscopy and a descriptive rating scaleStefan Smesny
Department of Psychiatry, University of Jena, Philosophenweg 3, D 07743, Jena, Germany
J Psychiatr Res 37:237-47. 2003..Niacin sensitivity in high risk populations and the specificity of impaired skin response are subjects of further investigation...
Hippocampal event-related potentials to tone duration deviance in a passive oddball paradigm in humansTimm Rosburg
Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Neuroimage 37:274-81. 2007..The current study provides evidence that the MMN is part of a multistage comparison process and that the rhinal cortex is part of its underlying cortical network...
Towards a functional topography of sensory gating areas: invasive P50 recording and electrical stimulation mapping in epilepsy surgery candidatesMartin Kurthen
Department of Epileptology, University of Bonn, Germany
Psychiatry Res 155:121-33. 2007..Results suggest that the early stage of sensory gating already involves a top-down modulation of sensory input by frontal areas...
Mid-latency auditory-evoked responses and sensory gating in focal epilepsy: a preliminary explorationNash N Boutros
Wayne State University School of Medicine, Department of Psychiatry and Behavioral Neurosciences, Detroit, MI 48207, USA
J Neuropsychiatry Clin Neurosci 18:409-16. 2006..Though alteration of sensory gating can be demonstrated in epileptic patients, it seems to be qualitatively different from alterations reported in association with schizophrenia...
Habituation of auditory evoked potentials in intracranial and extracranial recordingsTimm Rosburg
Department of Epileptology, University of Bonn, D 53105 Bonn, Germany
Psychophysiology 43:137-44. 2006..This dissociation between the intracranial and scalp recordings might be explained by a different sensitivity of the two measurements for N100 generators...
Subdural recordings of the mismatch negativity (MMN) in patients with focal epilepsyTimm Rosburg
Department of Epileptology, University of Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
Brain 128:819-28. 2005..Current findings have, however, to be interpreted with caution owing to the placement and limited extension of the used electrode arrays...
Short-term habituation of the intracranially recorded auditory evoked potentials P50 and N100Timm Rosburg
Department of Epileptology, University of Bonn, Sigmund Freud Street 25, D 53105 Bonn, Germany
Neurosci Lett 372:245-9. 2004..Current results indicate that the P50 suppression as investigated in sensory gating experiments seems to be completed after the 2nd stimulus...
Sensory gating in epilepsy - effects of the lateralization of hippocampal sclerosisTimm Rosburg
Department of Epileptology, University of Bonn, Sigmund Freud Str 25, D 53105 Bonn, Germany
Clin Neurophysiol 119:1310-9. 2008..The role of the hippocampus in sensory gating is unresolved as yet. The current study was conducted in order to examine the effects of hippocampal lesions on the function of auditory sensory gating...
Intracranially recorded memory-related potentials reveal higher posterior than anterior hippocampal involvement in verbal encoding and retrievalEva Ludowig
Department of Epileptology, University of Bonn, Bonn, Germany
J Cogn Neurosci 20:841-51. 2008..Both effects were larger the further posterior an electrode was located in the hippocampus. Findings are suggestive for a predominant posterior hippocampal involvement in both verbal encoding and retrieval...
