Jurgen Popp

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. pmc A study of Docetaxel-induced effects in MCF-7 cells by means of Raman microspectroscopy
    Katharina Hartmann
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 403:745-53. 2012
  2. pmc Raman spectroscopic detection of anthrax endospores in powder samples
    S Stöckel
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Jena, Germany
    Angew Chem Int Ed Engl 51:5339-42. 2012
  3. ncbi request reprint A new calibration concept for a reproducible quantitative detection based on SERS measurements in a microfluidic device demonstrated on the model analyte adenine
    Evelyn Kämmer
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Phys Chem Chem Phys 16:9056-63. 2014
  4. pmc Chemotaxonomic identification of single bacteria by micro-Raman spectroscopy: application to clean-room-relevant biological contaminations
    Petra Rosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Appl Environ Microbiol 71:1626-37. 2005
  5. ncbi request reprint Hyperspectral unmixing of Raman micro-images for assessment of morphological and chemical parameters in non-dried brain tumor specimens
    Norbert Bergner
    Institute of Photonic Technology, Albert Einstein Straße 9, 07745, Jena, Germany
    Anal Bioanal Chem 405:8719-28. 2013
  6. ncbi request reprint The excited-state chemistry of protochlorophyllide a: a time-resolved fluorescence study
    Benjamin Dietzek
    Institut fur Physikalische Chemie, Bayerische Julius Maximilians Universität Würzburg, Am Hubland, 97074 Wurzburg, Germany
    Chemphyschem 7:1727-33. 2006
  7. ncbi request reprint On the way to nanometer-sized information of the bacterial surface by tip-enhanced Raman spectroscopy
    Ute Neugebauer
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, 07743 Jena, Germany
    Chemphyschem 7:1428-30. 2006
  8. doi request reprint Widely tuneable fiber optical parametric amplifier for coherent anti-Stokes Raman scattering microscopy
    Mario Chemnitz
    Institute for Applied Physics, Abbe Center of Photonics, Friedrich Schiller Universtity Jena, Jena, Germany
    Opt Express 20:26583-95. 2012
  9. doi request reprint Expanding multimodal microscopy by high spectral resolution coherent anti-Stokes Raman scattering imaging for clinical disease diagnostics
    Tobias Meyer
    Institute of Photonic Technology Jena, Jena, Germany
    Anal Chem 85:6703-15. 2013
  10. doi request reprint Light-induced dynamics in conjugated bis(terpyridine) ligands--a case study toward photoactive coordination polymers
    Ronald Siebert
    Institute for Physical Chemistry IPC, Friedrich Schiller University of Jena, Helmholtzweg 4, 07743 Jena, Germany
    Macromol Rapid Commun 33:481-97. 2012

Collaborators

Detail Information

Publications90

  1. pmc A study of Docetaxel-induced effects in MCF-7 cells by means of Raman microspectroscopy
    Katharina Hartmann
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 403:745-53. 2012
    ..Thereby we were able to differentiate treated from untreated MCF-7 cells and to quantify the cell-drug response by utilizing linear discriminant analysis models...
  2. pmc Raman spectroscopic detection of anthrax endospores in powder samples
    S Stöckel
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Jena, Germany
    Angew Chem Int Ed Engl 51:5339-42. 2012
  3. ncbi request reprint A new calibration concept for a reproducible quantitative detection based on SERS measurements in a microfluidic device demonstrated on the model analyte adenine
    Evelyn Kämmer
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Phys Chem Chem Phys 16:9056-63. 2014
    ..In doing so, a vast improvement in the quantification using SERS, especially in view of the comparability, reproducibility and repeatability, is demonstrated. ..
  4. pmc Chemotaxonomic identification of single bacteria by micro-Raman spectroscopy: application to clean-room-relevant biological contaminations
    Petra Rosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Appl Environ Microbiol 71:1626-37. 2005
    ....
  5. ncbi request reprint Hyperspectral unmixing of Raman micro-images for assessment of morphological and chemical parameters in non-dried brain tumor specimens
    Norbert Bergner
    Institute of Photonic Technology, Albert Einstein Straße 9, 07745, Jena, Germany
    Anal Bioanal Chem 405:8719-28. 2013
    ..The role of non-linear Raman modalities to speed-up image acquisition is discussed. ..
  6. ncbi request reprint The excited-state chemistry of protochlorophyllide a: a time-resolved fluorescence study
    Benjamin Dietzek
    Institut fur Physikalische Chemie, Bayerische Julius Maximilians Universität Würzburg, Am Hubland, 97074 Wurzburg, Germany
    Chemphyschem 7:1727-33. 2006
    ....
  7. ncbi request reprint On the way to nanometer-sized information of the bacterial surface by tip-enhanced Raman spectroscopy
    Ute Neugebauer
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, 07743 Jena, Germany
    Chemphyschem 7:1428-30. 2006
  8. doi request reprint Widely tuneable fiber optical parametric amplifier for coherent anti-Stokes Raman scattering microscopy
    Mario Chemnitz
    Institute for Applied Physics, Abbe Center of Photonics, Friedrich Schiller Universtity Jena, Jena, Germany
    Opt Express 20:26583-95. 2012
    ..CARS spectroscopy and microscopy is demonstrated, probing different molecular vibrational modes within the accessible region between 1200cm(-1) and 3800cm(-1)...
  9. doi request reprint Expanding multimodal microscopy by high spectral resolution coherent anti-Stokes Raman scattering imaging for clinical disease diagnostics
    Tobias Meyer
    Institute of Photonic Technology Jena, Jena, Germany
    Anal Chem 85:6703-15. 2013
    ..Transfer of this highly precise but compact and simple to use imaging approach into clinical settings is expected in the near future. ..
  10. doi request reprint Light-induced dynamics in conjugated bis(terpyridine) ligands--a case study toward photoactive coordination polymers
    Ronald Siebert
    Institute for Physical Chemistry IPC, Friedrich Schiller University of Jena, Helmholtzweg 4, 07743 Jena, Germany
    Macromol Rapid Commun 33:481-97. 2012
    ....
  11. doi request reprint Characterization of atherosclerotic plaque depositions by Raman and FTIR imaging
    Annika Lattermann
    University Hospital Friedrich Schiller University of Jena, Clinic for Internal Medicine I, Jena, Germany
    J Biophotonics 6:110-21. 2013
    ..These results correlate well with histopathology. The described method is a promising tool for easy and fast molecular imaging of atherosclerosis...
  12. doi request reprint A concept to tailor electron delocalization: applying QTAIM analysis to phenyl-terpyridine compounds
    Martin Presselt
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    J Phys Chem A 114:13163-74. 2010
    ..Furthermore, the ellipticity in the BCP of the py-ph bond is related to the corresponding geometrical properties (e.g., bond length and dihedral angle) and to the DFT-calculated HOMO and LUMO energies...
  13. doi request reprint Ultrafast plasmon dynamics and evanescent field distribution of reproducible surface-enhanced Raman-scattering substrates
    Dana Cialla
    Institute of Physical Chemistry, Friedrich Schiller University Jena Jenaer Biochip Initiative, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 394:1811-8. 2009
    ....
  14. doi request reprint Analysis of single blood cells for CSF diagnostics via a combination of fluorescence staining and micro-Raman spectroscopy
    Michaela Harz
    Institute of Physical Chemistry, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Analyst 133:1416-23. 2008
    ..This capability with the possibility of accurate and rapid blood cell identification in cerebrospinal fluid is extremely promising for implementation in clinical diagnostics...
  15. ncbi request reprint Self-healing mechanism of metallopolymers investigated by QM/MM simulations and Raman spectroscopy
    Stephan Kupfer
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Phys Chem Chem Phys 16:12422-32. 2014
    ..However, such calculations on model clusters revealed relatively strong binding of the clusters, which renders reversible cluster breaking and reformation upon temperature cycling in the range up to 100 °C unlikely...
  16. doi request reprint Synthesis and characterization of regioselective substituted tetrapyridophenazine ligands and their Ru(II) complexes
    Michael Karnahl
    Institute of Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, August Bebel Strasse 2, 07743, Jena, Germany
    Dalton Trans 39:2359-70. 2010
    ..A clear influence caused by the electronic effects of the different type and position of the substituents of tpphz on the photophysical behavior was observed...
  17. ncbi request reprint Resonance-Raman spectro-electrochemistry of intermediates in molecular artificial photosynthesis of bimetallic complexes
    Linda Zedler
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chem Commun (Camb) 50:5227-9. 2014
    ....
  18. doi request reprint Alignment-free, all-spliced fiber laser source for CARS microscopy based on four-wave-mixing
    Martin Baumgartl
    Institute of Applied Physics, Abbe Center of Photonics, Friedrich Schiller Universitat Jena, Albert Einstein Str 15, 07745 Jena, Germany
    Opt Express 20:21010-8. 2012
    ..Due to its simplicity, compactness, maintenance-free operation, and ease-of-use the presented low-cost laser is an ideal source for bio-medical applications outside laser laboratories and in particular inside clinics...
  19. ncbi request reprint Quartz microfluidic chip for tumour cell identification by Raman spectroscopy in combination with optical traps
    Sebastian Dochow
    Institute of Photonic Technology, Jena, Germany
    Anal Bioanal Chem 405:2743-6. 2013
    ..Mean sensitivity and specificity determined by iterated 10-fold cross validation were 96 and 99 %, respectively, for the distinction of leucocytes extracted from blood, breast cancer cells BT-20 and MCF-7, and leukaemia cells OCI-AML3...
  20. doi request reprint Online-calibration for reliable and robust lab-on-a-chip surface enhanced Raman spectroscopy measurement in a liquid/liquid segmented flow
    Anne März
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany
    Anal Chem 83:8337-40. 2011
    ..In this contribution, we present a new approach to achieve reliable and robust measurements based on segmented flow LOC-SERS via online-wavenumber calibration...
  21. doi request reprint STXM and NanoSIMS investigations on EPS fractions before and after adsorption to goethite
    Xinran Liu
    Institut fur Geowissenschaften, Friedrich Schiller Universitat Jena, Germany
    Environ Sci Technol 47:3158-66. 2013
    ..e., of two materials which will strongly differ in their reactive sites. This will finally affect further adsorption, the particle mobility and eventually also colloidal stability...
  22. doi request reprint Protein-induced excited-state dynamics of protochlorophyllide
    Robert Hanf
    Institute for Physical Chemistry and Abbe Centre of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, D 07743 Jena, Germany
    J Phys Chem A 115:7873-81. 2011
    ..The possible relevance of this result for the catalytic reaction in the enzyme POR is discussed...
  23. ncbi request reprint UV cross-linking of unmodified DNA on glass surfaces
    Thomas Schüler
    Jenaer Biochip Initiative, Institute of Physical Chemistry, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Anal Bioanal Chem 395:1097-105. 2009
    ..However, higher binding rates can be achieved when using amino-modified oligonucleotides on an epoxy surface. The limit of detection for the used settings was 5 pM...
  24. pmc Towards multiple readout application of plasmonic arrays
    Dana Cialla
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Beilstein J Nanotechnol 2:501-8. 2011
    ..The results shown open the way to more flexible use of plasmonic arrays in bioanalytics...
  25. doi request reprint Analysis of the cytochrome distribution via linear and nonlinear Raman spectroscopy
    Angela Walter
    Institute of Physical Chemistry, Friedrich Schiller University, Helmholtzweg 4, 07743 Jena, Germany
    Analyst 135:908-17. 2010
    ..commune or other basidiomycetous fungi, by means of resonance Raman microspectroscopy and CARS microscopy. These Raman methods bear the potential of label-free in vivo mitochondria localization and investigation...
  26. doi request reprint Morphology-sensitive Raman modes of the malaria pigment hemozoin
    Torsten Frosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Analyst 134:1126-32. 2009
    ..830 nm. In conclusion, resonance Raman micro-spectroscopy with lambda(exc.) = 647 nm was shown to have great potential as an analytical tool to probe the morphology of hematin samples...
  27. doi request reprint The switch that wouldn't switch--unexpected luminescence from a ruthenium(II)-dppz-complex in water
    Matthias Schwalbe
    Institute of Inorganic and Analytical Chemistry, August Bebel Str 2, 07743 Jena, Germany
    Dalton Trans 39:2768-71. 2010
    ..The complex [(dmcb)(2)Ru(dppz)](PF(6))(2) shows unexpected luminescence in water implying fundamentally different excited state relaxation pathways than are typically observed for complexes of this kind...
  28. doi request reprint Towards a quantitative SERS approach--online monitoring of analytes in a microfluidic system with isotope-edited internal standards
    Anne März
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Jena, Germany
    J Biophotonics 2:232-42. 2009
    ..To the best of our knowledge these are the first measurements combining the above mentioned concepts in order to correct for differences in the enhancement behaviour of the respective colloid...
  29. doi request reprint Towards automated segmentation of cells and cell nuclei in nonlinear optical microscopy
    Anna Medyukhina
    Institute of Photonic Technology IPHT Jena eV, Jena, Germany
    J Biophotonics 5:878-88. 2012
    ..The results are important for the development of NLO microscopy into a clinically relevant diagnostic tool...
  30. doi request reprint From bulk to single-cell classification of the filamentous growing Streptomyces bacteria by means of Raman spectroscopy
    Angela Walter
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat, Helmholtzweg 4, 07743 Jena, Germany
    Appl Spectrosc 65:1116-25. 2011
    ..The classification utilizing a tree-like classifier is also applied to the Streptomyces single-cell spectra, resulting in classification accuracies between 80 and 93% for the investigated Streptomyces species...
  31. doi request reprint Raman spectroscopy-an innovative and versatile tool to follow the respirational activity and carbonate biomineralization of important cave bacteria
    Robert Keiner
    Institute of Photonic Technology, Institute for Physical Chemistry, Institute of Ecology, and Abbe School of Photonics, Friedrich Schiller University, Jena, Germany
    Anal Chem 85:8708-14. 2013
    ....
  32. doi request reprint Tumour cell identification by means of Raman spectroscopy in combination with optical traps and microfluidic environments
    Sebastian Dochow
    Institute of Photonic Technology, Jena, Germany
    Lab Chip 11:1484-90. 2011
    ..Implementation into microfluidic environments enables a high degree of automation that is required to improve the throughput of the approach for Raman activated cell sorting...
  33. doi request reprint Toward improving fine needle aspiration cytology by applying Raman microspectroscopy
    Melanie Becker-Putsche
    University of Jena, Institute of Physical Chemistry and Abbe Center of Photonics, Helmholtzweg 4, 07743 Jena, Germany
    J Biomed Opt 18:047001. 2013
    ..This work shows the applicability of Raman spectroscopy and statistical data handling in analyzing cancer-relevant biochemical information for advanced medical diagnosis on the single-cell level...
  34. doi request reprint How to pre-process Raman spectra for reliable and stable models?
    Thomas Bocklitz
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University, Jena, Germany
    Anal Chim Acta 704:47-56. 2011
    ..The suggested GA procedure results in models, which have a higher precision and are more stable against corrupting effects...
  35. doi request reprint SERS as tool for the analysis of DNA-chips in a microfluidic platform
    Katharina K Strelau
    Jenaer Biochip Initiative, Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07745 Jena, Germany
    Anal Bioanal Chem 396:1381-4. 2010
    ..With this setup, we are able to distinguish between different complementary and non-complementary target sequences in one sample solution...
  36. doi request reprint Microarray-based detection of dye-labeled DNA by SERRS using particles formed by enzymatic silver deposition
    Katharina Konstanze Hering
    Jenaer Biochip Initiative, Institute of Physical Chemistry, Friedrich Schiller Universitat Jena, Helmholtzweg 4, 07745 Jena, Germany
    Chemphyschem 9:867-72. 2008
    ..The nanoparticles are characterized and their ability for use as SERS- and SERRS-active substrate is estimated. Three different Raman-active dyes are investigated for their potential for involvement in sequence specific DNA analysis...
  37. doi request reprint Raman spectroscopic detection of physiology changes in plasmid-bearing Escherichia coli with and without antibiotic treatment
    Angela Walter
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat, Jena, Germany
    Anal Bioanal Chem 400:2763-73. 2011
    ..Independent cultural replicates of either ampicillin-challenged or non-challenged cultures are successfully identified with identification rates of over 90%...
  38. ncbi request reprint Identification of meat-associated pathogens via Raman microspectroscopy
    Susann Meisel
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Food Microbiol 38:36-43. 2014
    ..The test samples were correctly assigned to their genus and for the most part down to the species-level i.e. a differentiation from closely-related non-pathogenic members was achieved. ..
  39. doi request reprint Protonation effects on the resonance Raman properties of a novel (terpyridine)Ru(4H-imidazole) complex: an experimental and theoretical case study
    Stephan Kupfer
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743, Jena, Germany
    Phys Chem Chem Phys 13:15580-8. 2011
    ..Finally, the examination of the molecular orbitals and of the RR spectra for the MLCT state shows that protonation favors a charge transfer excitation to the 4H-imidazole ligand...
  40. doi request reprint Sample size planning for classification models
    Claudia Beleites
    Department of Spectroscopy and Imaging, Institute of Photonic Technology, Jena, Germany
    Anal Chim Acta 760:25-33. 2013
    ....
  41. doi request reprint Metal-mediated reaction modeled on nature: the activation of isothiocyanates initiated by zinc thiolate complexes
    Wilhelm A Eger
    Institut fur Organische Chemie und Makromolekulare Chemie, Friedrich Schiller Universitat Jena, Humboldtstrasse 10, 07743 Jena, Germany
    Inorg Chem 50:3223-33. 2011
    ..In addition, the presented synthetic pathways can offer a completely new access to a variety of dithiocarbamates...
  42. doi request reprint Detection of thiopurine methyltransferase activity in lysed red blood cells by means of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS)
    Anne März
    Institute of Physical Chemisty, Friedrich Schiller University, Jena, Germany
    Anal Bioanal Chem 400:2755-61. 2011
    ..Being able to determine the TPMT activity before starting a treatment using 6-mercaptopurine, an optimized dosage can be applied to each patient and serious toxicity appearing within thiopurine treatment will be prevented...
  43. ncbi request reprint Catalytic efficiency of a photoenzyme-an adaptation to natural light conditions
    Robert Hanf
    Friedrich Schiller Universitat Jena, Institut fur Physikalische Chemie, Helmholtzweg 4, 07743 Jena Germany, Fax 49 3641 948302
    Chemphyschem 13:2013-5. 2012
    ..It becomes evident that "red" photons are more efficiently utilized in enzyme catalysis than "blue" photons. This shows an adaptation of the enzyme activity to the natural light conditions...
  44. doi request reprint Multimodal nonlinear microscopic investigations on head and neck squamous cell carcinoma: toward intraoperative imaging
    Tobias Meyer
    Institute of Photonic Technology, Jena, Germany
    Head Neck 35:E280-7. 2013
    ..A promising noninvasive alternative is nonlinear optical imaging, which is capable of in vivo tissue visualization for tumor typing and grading...
  45. ncbi request reprint Excited-state annihilation in a homodinuclear ruthenium complex
    Christian Kuhnt
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Jena Center of Soft Matter and Abbe Center of Photonics, Helmhotzweg 4, 07743 Jena, Germany
    Chem Commun (Camb) 47:3820-1. 2011
    ..The observation of pump-intensity dependent triplet-triplet annihilation highlights the importance of considering various loss mechanisms in the design of artificial photosynthetic assemblies...
  46. doi request reprint Towards a fast, high specific and reliable discrimination of bacteria on strain level by means of SERS in a microfluidic device
    Angela Walter
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Jena, Germany
    Lab Chip 11:1013-21. 2011
    ..Within this contribution the potential of our approach of bacterial identification for future application is discussed, focusing on the time-benefit and the combination with other microfluidic applications...
  47. doi request reprint Toward a spectroscopic hemogram: Raman spectroscopic differentiation of the two most abundant leukocytes from peripheral blood
    Anuradha Ramoji
    Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany
    Anal Chem 84:5335-42. 2012
    ..This marks a promising step toward automated Raman spectroscopic blood analysis which holds the potential not only to assign the numbers of the cells but also to yield important biochemical information...
  48. doi request reprint A comparative Raman and CARS imaging study of colon tissue
    Christoph Krafft
    Institute of Photonic Technology, Germany, Albert Einstein Str 9, 07745 Jena, Germany
    J Biophotonics 2:303-12. 2009
    ..This first comparison establishes the foundation for further development of the CARS technology to assess tissue...
  49. doi request reprint Ru dye functionalized Au-SiO2@TiO2 and Au/Pt-SiO2@TiO2 nanoassemblies for surface-plasmon-induced visible light photocatalysis
    Frank Theil
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, Jena, Germany Leibniz Institute of Photonic Technology IPHT Jena e V, Albert Einstein Str 9, Jena, Germany
    J Colloid Interface Sci 421:114-21. 2014
    ..The photocatalytic activity of the nanostructures shows up to 52% higher first order rate constants compared to the corresponding nanostructures without further dye functionalization. ..
  50. pmc Raman spectroscopy as a potential tool for detection of Brucella spp. in milk
    Susann Meisel
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany
    Appl Environ Microbiol 78:5575-83. 2012
    ..The measurements we performed at the single-cell level thus allow fast identification within a few hours without a demanding process for sample preparation...
  51. ncbi request reprint On-line monitoring and identification of bioaerosols
    Petra Rosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Anal Chem 78:2163-70. 2006
    ..Since only the biotic particles are of interest, the analysis time can be minimized due to reduction of the data set. The biotic particles are then analyzed further with Raman spectroscopy and identified with a support vector machine...
  52. ncbi request reprint Quantitative online detection of low-concentrated drugs via a SERS microfluidic system
    Katrin R Ackermann
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chemphyschem 8:2665-70. 2007
    ....
  53. ncbi request reprint SERS: a versatile tool in chemical and biochemical diagnostics
    Katharina Hering
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, 07743, Jena, Germany
    Anal Bioanal Chem 390:113-24. 2008
    ..Here, rough coin metal surfaces enhance the Raman signal by a factor of 10(4)-10(15), depending on the applied method. In this review we discuss recent developments in SERS spectroscopy and their impact on different research fields...
  54. ncbi request reprint Raman spectroscopic imaging for the real-time detection of chemical changes associated with docetaxel exposure
    Katharina Bräutigam
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chemphyschem 14:550-3. 2013
    ..The work presented paves the way for establishing Raman spectroscopy as a monitoring tool of the effectiveness of a chemotherapy treatment and can therefore be seen as a step towards personalized therapy...
  55. doi request reprint Probing innovative microfabricated substrates for their reproducible SERS activity
    Dana Cialla
    Friedrich Schiller University Jena, Department of Physical Chemistry, Jenaer Biochip Initiative JBCI, Helmholtzweg 4, 07743 Jena, Germany
    Chemphyschem 9:758-62. 2008
    ..To test the SERS activity of these nanostar and nanodiamond arrays, a monolayer of the dye crystal violet is used. Enhancement factors are estimated to be at least 130 for the nanodiamond and 310 for the nanostar arrays...
  56. doi request reprint Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic
    Anne März
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Anal Bioanal Chem 402:2625-31. 2012
    ..With the new concept of binding the label molecule directly to the analyte molecule, the application of linkage compounds like antibodies or any other recognition molecules becomes dispensable...
  57. doi request reprint A disposable and cost efficient microfluidic device for the rapid chip-based electrical detection of DNA
    Thomas Schüler
    Jenaer Biochip Initiative, Friedrich Schiller University, Institute of Physical Chemistry, Helmholtzweg 4, Jena, Germany
    Biosens Bioelectron 25:15-21. 2009
    ..These first steps of automation and integration will help to realize a laboratory-independent bioanalytical tool, for the use outside of specialized laboratories for fast analysis of different chemical and biological applications...
  58. ncbi request reprint Surface-enhanced Raman spectroscopy (SERS): progress and trends
    Dana Cialla
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany
    Anal Bioanal Chem 403:27-54. 2012
    ..To benefit from synergies, SERS is combined with other methods, such as scanning probe microscopy and microfluidics, which illustrates the broad applications of this powerful technique...
  59. doi request reprint Self-healing polymer coatings based on crosslinked metallosupramolecular copolymers
    Stefan Bode
    Laboratory of Organic and Macromolecular Chemistry IOMC, Friedrich Schiller University Jena, Jena, Germany
    Adv Mater 25:1634-8. 2013
    ..Moreover, the influence of the comonomers on the thermal properties is studied in detail...
  60. doi request reprint Characterizing cytochrome c states--TERS studies of whole mitochondria
    René Böhme
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Chem Commun (Camb) 47:11453-5. 2011
    ..Protein structures (cytochrome c) were visualized by TERS measurements on whole mitochondria referring to specific spectral features describing the electronic state of the heme moiety...
  61. doi request reprint Culture independent Raman spectroscopic identification of urinary tract infection pathogens: a proof of principle study
    Sandra Kloss
    Institute of Physical Chemistry and Abbe Center of Photonics, University of Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Anal Chem 85:9610-6. 2013
    ..These results demonstrate that Raman microspectroscopy in combination with support vector machines allow an identification of important UTI bacteria within two hours without the need of a culture step. ..
  62. doi request reprint Localizing and identifying living bacteria in an abiotic environment by a combination of Raman and fluorescence microscopy
    Mario Krause
    Institute for Physical Chemistry, University of Jena, Helmholtzweg 4, 07743 Jena, Germany
    Anal Chem 80:8568-75. 2008
    ..The living cells were identified by means of Raman spectroscopy in combination with a support vector machine. Furthermore, the localization of bacterial cells in a mix of abiotic particles is demonstrated...
  63. doi request reprint Raman spectroscopic determination of norbixin and tartrazine in sugar
    Ute Uhlemann
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller Universitat, Jena, Germany
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 29:1244-55. 2012
    ..A detection limit of 250 ng g⁻¹ for norbixin and 989 ng g⁻¹ for tartrazine in solid sugar samples could be reached by logistic regression...
  64. ncbi request reprint Quality control of commercially available essential oils by means of Raman spectroscopy
    Katrin R Strehle
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    J Agric Food Chem 54:7020-6. 2006
    ..In addition, cross-sections of anise seeds were analyzed applying the Raman mapping technique to localize and investigate the distribution of the oil in situ...
  65. ncbi request reprint UV Raman spectroscopy--a technique for biological and mineralogical in situ planetary studies
    Nicolae Tarcea
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Spectrochim Acta A Mol Biomol Spectrosc 68:1029-35. 2007
    ..Making use of the resonance effects, spectra of microorganisms were recorded with a high S/N ratio, allowing afterwards a very precise identification and classification (to the strain level) of the measured samples...
  66. doi request reprint Direct analysis of clinical relevant single bacterial cells from cerebrospinal fluid during bacterial meningitis by means of micro-Raman spectroscopy
    Michaela Harz
    Institute of Physical Chemistry, Friedrich Schiller Universitat Jena, Helmholtzweg 4, Jena, Germany
    J Biophotonics 2:70-80. 2009
    ..meningitidis cells from patients with bacterial meningitis could be achieved...
  67. ncbi request reprint In situ localization and structural analysis of the malaria pigment hemozoin
    Torsten Frosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    J Phys Chem B 111:11047-56. 2007
    ....
  68. doi request reprint Dual emission from highly conjugated 2,2':6':2″-terpyridine complexes-a potential route to white emitters
    Ronald Siebert
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Macromol Rapid Commun 31:883-8. 2010
    ..Thus, by structurally tuning the electronic coupling of the ππ* and the MLCT states a new synthetic route toward white emitters, which can subsequently be incorporated into polymers, is opened...
  69. ncbi request reprint Droplet formation via flow-through microdevices in Raman and surface enhanced Raman spectroscopy--concepts and applications
    Anne März
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Lab Chip 11:3584-92. 2011
    ..Within this contribution, previous reported applications on droplet-based flow-through Raman and SERS approaches and the additional benefit with regard to the importance in the field of analytics are considered...
  70. doi request reprint Structural analysis of the antimalarial drug halofantrine by means of Raman spectroscopy and density functional theory calculations
    Torsten Frosch
    Friedrich Schiller Universitat Jena, Institut fur Physikalische Chemie, Jena, Germany
    J Biomed Opt 15:041516. 2010
    ..Complementary IR spectroscopy is performed for an investigation of vibrations of polar functional groups of the halofantrine molecule...
  71. doi request reprint Accumulating advantages, reducing limitations: multimodal nonlinear imaging in biomedical sciences - the synergy of multiple contrast mechanisms
    Tobias Meyer
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    J Biophotonics 6:887-904. 2013
    ..The third part focuses on recent applications in life science fundamental research and biomedical diagnostics as well as future clinical applications...
  72. doi request reprint Utilizing ancillary ligands to optimize the photophysical properties of 4H-imidazole ruthenium dyes
    Maria Wächtler
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena Germany Institute of Photonic Technology Jena IPHT e V Albert Einstein Str 9, 07745 Jena Germany
    Chemphyschem 14:2973-83. 2013
    ....
  73. ncbi request reprint The influence of intracellular storage material on bacterial identification by means of Raman spectroscopy
    Valerian Ciobotă
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Anal Bioanal Chem 397:2929-37. 2010
    ..Although the presence of PHB induced severe changes in the Raman spectra, our results suggest that Raman spectroscopy can be successfully used for identification as long as the bacteria are not in the stationary phase...
  74. ncbi request reprint Identification and differentiation of single cells from peripheral blood by Raman spectroscopic imaging
    Ute Neugebauer
    Institute of Photonic Technology, Jena, Germany
    J Biophotonics 3:579-87. 2010
    ..The model was successfully applied to identify single cells from an independent mixture of cells based on their vibrational spectra. The classification was confirmed by fluorescence staining of the cells after the Raman measurement...
  75. pmc Toward in vivo chemical imaging of epicuticular waxes
    Ina Weissflog
    Institute of Photonic Technology, Jena, Germany
    Plant Physiol 154:604-10. 2010
    ..aff. deliciosa). We anticipate that the work presented will open a doorway for online monitoring of formation and alterations of epicuticular wax layers...
  76. doi request reprint Chip-on-foil devices for DNA analysis based on inkjet-printed silver electrodes
    Sebastian Wünscher
    Laboratory of Organic and Macromolecular Chemistry IOMC, Friedrich Schiller University Jena, Humboldtstr 10, 07743 Jena, Germany
    Lab Chip 14:392-401. 2014
    ..The proof-of-principle experiments successfully demonstrated the applicability of these convenient chip-on-foil devices for nucleic acid based pathogen detection. ..
  77. doi request reprint Protochlorophyllide a: A Comprehensive Photophysical Picture
    Benjamin Dietzek
    Institute for Physical Chemistry, University Jena, Lessingstrasse 10, 07743 Jena, Germany
    Chemphyschem 10:144-50. 2009
    ..The implications of this finding with respect to the photochemistry of NADPH:protochlorophyllide oxidoreductase (POR) are discussed...
  78. doi request reprint Spatially resolved investigation of the oil composition in single intact hyphae of Mortierella spp. with micro-Raman spectroscopy
    Ute Münchberg
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Biochim Biophys Acta 1831:341-9. 2013
    ....
  79. ncbi request reprint The molecular mechanism of dual emission in terpyridine transition metal complexes--ultrafast investigations of photoinduced dynamics
    Ronald Siebert
    Institute for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany
    Phys Chem Chem Phys 13:1606-17. 2011
    ....
  80. doi request reprint Assessment of two isolation techniques for bacteria in milk towards their compatibility with Raman spectroscopy
    Susann Meisel
    Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany
    Analyst 136:4997-5005. 2011
    ....
  81. doi request reprint Unsupervised unmixing of Raman microspectroscopic images for morphochemical analysis of non-dried brain tumor specimens
    Norbert Bergner
    Institute of Photonic Technology, Albert Einstein Straße 9, 07745, Jena, Germany
    Anal Bioanal Chem 403:719-25. 2012
    ..The results are compared for both unmixing algorithms and with previously reported supervised spectral decomposition techniques...
  82. pmc Calcite biomineralization by bacterial isolates from the recently discovered pristine karstic herrenberg cave
    Anna Rusznyák
    Aquatic Geomicrobiology Group, Institute of Ecology, Friedrich Schiller University Jena, Jena, Germany
    Appl Environ Microbiol 78:1157-67. 2012
    ....
  83. ncbi request reprint Ruthenium(II) photosensitizers of tridentate click-derived cyclometalating ligands: a joint experimental and computational study
    Benjamin Schulze
    Laboratory of Organic and Macromolecular Chemistry IOMC, Friedrich Schiller University Jena, Humboldtstr 10, 07743 Jena, Germany
    Chemistry 18:4010-25. 2012
    ..Thus, the complexes reveal great potential for dye-sensitized solar-cell applications...
  84. doi request reprint Disruption-free imaging by Raman spectroscopy reveals a chemical sphere with antifouling metabolites around macroalgae
    Katharina Grosser
    IAAC, Bioorganic Analytics, Friedrich Schiller University Jena, Lessingstr 8, Jena, 07743, Germany
    Biofouling 28:687-96. 2012
    ....
  85. doi request reprint Biochemical imaging below the diffraction limit--probing cellular membrane related structures by tip-enhanced Raman spectroscopy (TERS)
    René Böhme
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Jena, Germany
    J Biophotonics 3:455-61. 2010
    ..Since a spatial differentiation between different compositional domains is difficult to achieve by topographic features only, the combination of morphology and spectral data enables a much more detailed characterization of biomembranes...
  86. doi request reprint Derivation of correlation functions to predict bond properties of phenyl-CH bonds based on vibrational and (1)H NMR spectroscopic quantities
    Martin Presselt
    Institute of Physical Chemistry, Friedrich Schiller University Jena, Helmholzweg 4, 07743 Jena, Germany
    J Phys Chem A 114:10287-96. 2010
    ..Thus, ellipticities are best predicted using (1)H NMR data for the para position of monosubstituted benzene derivatives...
  87. ncbi request reprint In situ UV resonance Raman micro-spectroscopic localization of the antimalarial quinine in cinchona bark
    Torsten Frosch
    Institut fur Physikalische Chemie, Friedrich Schiller Universitat Jena, Helmholtzweg 4, D 07743 Jena, Germany
    J Phys Chem B 111:4171-7. 2007
    ....
  88. ncbi request reprint A reproducible surface-enhanced raman spectroscopy approach. Online SERS measurements in a segmented microfluidic system
    Katrin R Strehle
    Department for Physical Chemistry, Friedrich Schiller University Jena, Helmholtzweg 4, D 07743 Jena, Germany
    Anal Chem 79:1542-7. 2007
    ..The combination of the segmented microfluidic system with the highly sensitive SERS technique reaches in a reproducible quantification of analytes with the SERS technique...
  89. ncbi request reprint Distribution of amygdalin in apricot (Prunus armeniaca) seeds studied by Raman microscopic imaging
    Christoph Krafft
    Institute of Photonic Technology, Jena, Germany
    Appl Spectrosc 66:644-9. 2012
    ..The observed biological variability of the amygdalin distribution cannot yet be explained satisfactorily and requires further investigation...