Research Topics
| Götz NowakSummaryAffiliation: Friedrich Schiller University Country: Germany Publications
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Detail Information
Publications
The ecarin clotting time, a universal method to quantify direct thrombin inhibitorsGötz Nowak
Research Group Pharmacological Haemostaseology, Medical Faculty, Friedrich Schiller University Jena, Jena, Germany
Pathophysiol Haemost Thromb 33:173-83. 2003..g., for biochemical investigations, as a point-of-care method and for cardiac surgery. Advantages and disadvantages of these methods are discussed...
Platelet adhesion assay--a new quantitative whole blood test to measure platelet functionGötz Nowak
Friedrich Schiller University Jena, Medical Faculty, Research Group Pharmacological Haemostaseology, Jena, Germany
Semin Thromb Hemost 31:470-5. 2005..PADA was shown to be a simple reliable laboratory method for the detection of disturbed platelet function. The test requires low analytical efforts compared with other diagnostic platelet function tests...
Is platelet adhesion assay able to quantify drug-induced platelet dysfunction?Alrun Schumann
HaemoSys GmbH, Jena, Germany
Semin Thromb Hemost 31:476-81. 2005..Furthermore, patients having partial or full clopidogrel resistance were identified. Overdoses can be detected as well...
Measurement of maximum thrombin generation capacity in blood and plasma using the thrombin generation assay (THROGA)Götz Nowak
Friedrich Schiller University Jena, Medical Faculty, Research Group Pharmacological Haemostaseology, Drackendorfer Strasse 1, D 07747 Jena, Germany
Semin Thromb Hemost 33:508-14. 2007....
Anticoagulant efficacy of PEG-Hirudin in patients on maintenance hemodialysisKatrin Annett Pöschel
Department of Internal Medicine IV, Friedrich Schiller University, Jena, Germany
Kidney Int 65:666-74. 2004....
Pharmacology of recombinant hirudinGötz Nowak
Medical Faculty, Friedrich Schiller University, Jena, Germany
Semin Thromb Hemost 28:415-24. 2002..Recombinant hirudin (r-hirudin) is a product of genetic engineering that is identical to the hirudin found in nature and has the same biochemical and pharmacological characteristics as natural hirudin...
Heparin-induced thrombocytopenia (HIT II) - a drug-associated autoimmune diseaseGötz Nowak
University Hospital Jena, Research Group Pharmacological Haemostaseology, 07747 Jena, Germany
Thromb Haemost 102:887-91. 2009..By early and fast diagnostics and appropriate treatment severe complications of HIT II can be prevented...
Characterization of the postglomerular renal metabolism of lepirudin in healthy volunteersMichael Kautzleben
Research Unit Pharmacological Haemostaseology, Friedrich Schiller, University, Jena, Germany
Thromb Res 113:187-95. 2004..We examined the C-terminal amino acid degradation of lepirudin by the proximal kidney tubulus cells in humans as well as the antithrombotic efficacy of the metabolites and quantified the metabolite portions...
