Jochen G Mainz

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. ncbi request reprint Pathogenesis and management of nasal polyposis in cystic fibrosis
    Jochen G Mainz
    Cystic Fibrosis Center, Department of Paediatrics, Paediatric Pulmonology, Jena University Hospital, Kochstrasse 2, 07740 Jena, Germany
    Curr Allergy Asthma Rep 12:163-74. 2012
  2. ncbi request reprint Sinonasal inhalation of dornase alfa administered by vibrating aerosol to cystic fibrosis patients: A double-blind placebo-controlled cross-over trial
    Jochen G Mainz
    Department of Paediatrics, CF Center, Jena University Hospital, Kochstraße 2, 07745 Jena, Germany Electronic address
    J Cyst Fibros 13:461-70. 2014
  3. doi request reprint Sinonasal inhalation of tobramycin vibrating aerosol in cystic fibrosis patients with upper airway Pseudomonas aeruginosa colonization: results of a randomized, double-blind, placebo-controlled pilot study
    Jochen G Mainz
    Cystic Fibrosis Centre, Department of Pediatrics, Jena University Hospital, Jena, Germany
    Drug Des Devel Ther 8:209-17. 2014
  4. doi request reprint Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation
    J G Mainz
    CF Centre, Pediatric Pneumology, Jena University Hospital, Germany
    J Cyst Fibros 11:158-61. 2012
  5. doi request reprint Pathogenesis and management of nasal polyposis in cystic fibrosis
    Jochen G Mainz
    Cystic Fibrosis Center, Department of Paediatrics, Paediatric Pulmonology, Jena University Hospital, Jena, Germany
    Curr Allergy Asthma Rep 12:163-74. 2012
  6. doi request reprint Sinonasal inhalation of dornase alfa in CF: A double-blind placebo-controlled cross-over pilot trial
    Jochen G Mainz
    Department of Paediatrics, Cystic Fibrosis Centre, University Hospital of Jena, Kochstrasse 2, 07740 Jena, Germany
    Auris Nasus Larynx 38:220-7. 2011
  7. doi request reprint Management of chronic rhinosinusitis in CF
    Jochen G Mainz
    Cystic Fibrosis Centre, Department of Paediatrics Friedrich Schiller University of Jena, University Hospital of Jena, D 07740 Jena, Germany
    J Cyst Fibros 8:S10-4. 2009
  8. doi request reprint Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis
    J G Mainz
    Department of Pediatrics, University of Jena, Cystic Fibrosis Center, Jena, Germany
    Thorax 64:535-40. 2009
  9. doi request reprint Substantially reduced calcaneal bone ultrasound parameters in severe untreated asthma
    Jochen G Mainz
    Department of Pediatrics, University of Jena, DE 07740 Jena, Germany
    Respiration 78:230-3. 2009
  10. doi request reprint [Terminal pulmonary insufficiency due to mild cystic fibrosis?]
    J G Mainz
    Mukoviszidosezentrum an der Friedrich Schiller Universität Jena
    Pneumologie 63:231-4. 2009

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Pathogenesis and management of nasal polyposis in cystic fibrosis
    Jochen G Mainz
    Cystic Fibrosis Center, Department of Paediatrics, Paediatric Pulmonology, Jena University Hospital, Kochstrasse 2, 07740 Jena, Germany
    Curr Allergy Asthma Rep 12:163-74. 2012
    ....
  2. ncbi request reprint Sinonasal inhalation of dornase alfa administered by vibrating aerosol to cystic fibrosis patients: A double-blind placebo-controlled cross-over trial
    Jochen G Mainz
    Department of Paediatrics, CF Center, Jena University Hospital, Kochstraße 2, 07745 Jena, Germany Electronic address
    J Cyst Fibros 13:461-70. 2014
    ..After a small pilot study to assess sinonasal inhalation of dornase alfa and placebo (isotonic saline) on potential sinonasal outcome measures, we present the subsequent prospective double-blind placebo-controlled crossover-trial...
  3. doi request reprint Sinonasal inhalation of tobramycin vibrating aerosol in cystic fibrosis patients with upper airway Pseudomonas aeruginosa colonization: results of a randomized, double-blind, placebo-controlled pilot study
    Jochen G Mainz
    Cystic Fibrosis Centre, Department of Pediatrics, Jena University Hospital, Jena, Germany
    Drug Des Devel Ther 8:209-17. 2014
    ..This trial assessed the effects of vibrating sinonasal inhalation of the antibiotic tobramycin in CF patients positive for P. aeruginosa in nasal lavage...
  4. doi request reprint Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation
    J G Mainz
    CF Centre, Pediatric Pneumology, Jena University Hospital, Germany
    J Cyst Fibros 11:158-61. 2012
    ....
  5. doi request reprint Pathogenesis and management of nasal polyposis in cystic fibrosis
    Jochen G Mainz
    Cystic Fibrosis Center, Department of Paediatrics, Paediatric Pulmonology, Jena University Hospital, Jena, Germany
    Curr Allergy Asthma Rep 12:163-74. 2012
    ....
  6. doi request reprint Sinonasal inhalation of dornase alfa in CF: A double-blind placebo-controlled cross-over pilot trial
    Jochen G Mainz
    Department of Paediatrics, Cystic Fibrosis Centre, University Hospital of Jena, Kochstrasse 2, 07740 Jena, Germany
    Auris Nasus Larynx 38:220-7. 2011
    ..This DBPC pilot-trial applying dornase alfa aims to evaluate outcome parameters and sample sizes for a subsequent efficacy trial...
  7. doi request reprint Management of chronic rhinosinusitis in CF
    Jochen G Mainz
    Cystic Fibrosis Centre, Department of Paediatrics Friedrich Schiller University of Jena, University Hospital of Jena, D 07740 Jena, Germany
    J Cyst Fibros 8:S10-4. 2009
    ..In summary, upper airway involvement in CF is undertreated and requires prospective investigation and an interdisciplinary consensus on diagnosis and therapy...
  8. doi request reprint Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis
    J G Mainz
    Department of Pediatrics, University of Jena, Cystic Fibrosis Center, Jena, Germany
    Thorax 64:535-40. 2009
    ..The upper airways (UAW) were shown to be a gateway for acquisition of opportunistic bacteria and to act as a reservoir for them. Therefore, tools for UAW assessment within CF routine care require evaluation...
  9. doi request reprint Substantially reduced calcaneal bone ultrasound parameters in severe untreated asthma
    Jochen G Mainz
    Department of Pediatrics, University of Jena, DE 07740 Jena, Germany
    Respiration 78:230-3. 2009
    ..On the contrary, ICS in low to medium dosages may allow regular growth, bone development and normalization of previously severe effects of the disease itself...
  10. doi request reprint [Terminal pulmonary insufficiency due to mild cystic fibrosis?]
    J G Mainz
    Mukoviszidosezentrum an der Friedrich Schiller Universität Jena
    Pneumologie 63:231-4. 2009
    ..We discuss the special features of CF treatment. Our report underlines the necessity for CF patients to be treated in specialised centres...
  11. doi request reprint Cross-sectional study on bone density-related sonographic parameters in children with asthma: correlation to therapy with inhaled corticosteroids and disease severity
    Jochen G Mainz
    Department of Pediatrics Pediatric Pulmonology, Friedrich Schiller University of Jena, Kochstrasse 2, Jena, Germany
    J Bone Miner Metab 26:485-92. 2008
    ..For differentiation of possible negative effect of ICS on ultrasonic bone quality and for evaluation of the potentials of the method, further longitudinal QUS assessment of asthmatics receiving a new ICS treatment is needed...
  12. ncbi request reprint Cystic fibrosis in 65- and 67-year-old siblings. Clinical feature and nasal potential difference measurement in patients with genotypes F508del and 2789+5G-->A
    J Mainz
    Department of Paediatrics, University of Jena, Jena, Germany
    Respiration 73:698-704. 2006
    ..In this regard this report can encourage CF patients to maintain a high level of physical activity in their daily lives...
  13. doi request reprint [Atypical cystic fibrosis. First diagnosed by chronic rhinosinusitis]
    J G Mainz
    Mukoviszidosezentrum für Kinder und Erwachsene am Universitätsklinikum der Friedrich Schiller Unversität, Kochstrasse 2, 07740, Jena
    HNO 57:804-7. 2009
    ..Atypical CF should be considered in chronic persistent rhinosinusitis even in patients with borderline sweat tests...
  14. ncbi request reprint Dynamics of soluble and cellular inflammatory markers in nasal lavage obtained from Cystic Fibrosis patients during intravenous antibiotic treatment
    Julia Hentschel
    CF Centre, Pediatrics, Jena University Hospital, Jena, Germany
    BMC Pulm Med 14:82. 2014
    ..Therefore, we assessed the effect of systemic antibiotics against pulmonary pathogens on sinonasal inflammation...
  15. ncbi request reprint Influences of nasal lavage collection-, processing- and storage methods on inflammatory markers--evaluation of a method for non-invasive sampling of epithelial lining fluid in cystic fibrosis and other respiratory diseases
    Julia Hentschel
    CF Center, Pediatrics, Jena University Hospital, Germany Electronic address
    J Immunol Methods 404:41-51. 2014
    ..However, the influences of collection-, processing- and storage-methods have not been sufficiently evaluated and standardized...
  16. ncbi request reprint [Early results of ultrasound based calculation of broadband ultrasound attenuation and speed of sound in children and adolescents suffering from asthma]
    A Malich
    Institut für Diagnostische und Interventionelle Radiologie, Friedrich Schiller Universitat, Jena
    Rofo 175:366-73. 2003
    ..To determine broadband ultrasound attenuation (BUA) and speed of sound (SOS) on the os caicis in asthmatic children. To correlate these findings with sex, age, weight and height, topical steroid intake, and asthma severity grade (ASG)...
  17. pmc Reduced nasal nitric oxide production in cystic fibrosis patients with elevated systemic inflammation markers
    Ruth K Michl
    Department of Paediatrics, Jena University Hospital, Jena, Germany
    PLoS ONE 8:e79141. 2013
    ..The aim of this study was to investigate the correlation between upper and lower airway NO levels and blood inflammatory parameters, CF-pathogen colonisation, and clinical data...
  18. doi request reprint Soluble inflammation markers in nasal lavage from CF patients and healthy controls
    Natalie Beiersdorf
    Department of Obstetrics, Placenta Laboratory, Jena University Hospital, D 07740 Jena, Germany
    J Cyst Fibros 12:249-57. 2013
    ..Nasal Lavage (NL) allows non-invasive repeated sampling of airway surface liquid. We compared inflammatory mediators in NL from CF-patients and healthy controls, and in CF in relation to sinonasal pathogen colonization...
  19. doi request reprint Homozygous CFTR mutation M348K in a boy with respiratory symptoms and failure to thrive. Disease-causing mutation or benign alteration?
    Julia Hentschel
    Institute of Human Genetics, Jena University Hospital, Kollegiengasse 10, 07743, Jena, Germany
    Eur J Pediatr 171:1039-46. 2012
    ..Conclusion: We assume that the homozygous alteration M348K is a harmless variant rather than a CF-causing mutation...
  20. doi request reprint Therapy of CF-patients with amitriptyline and placebo--a randomised, double-blind, placebo-controlled phase IIb multicenter, cohort-study
    Lutz Nährlich
    Department of Paediatrics, University Hospital Giessen, Giessen, Germany
    Cell Physiol Biochem 31:505-12. 2013
    ..aeruginosa in these mice...