J Liepert

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. ncbi request reprint Motor plasticity induced by synchronized thumb and foot movements
    J Liepert
    Neurologische Universitatsklinik, Friedrich Schiller University, Jena, Germany
    Exp Brain Res 125:435-9. 1999
  2. ncbi request reprint Task-dependent changes of intracortical inhibition
    J Liepert
    Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Exp Brain Res 118:421-6. 1998
  3. ncbi request reprint Motor cortex plasticity during constraint-induced movement therapy in stroke patients
    J Liepert
    Department of Neurology, Friedrich Schiller University of Jena, Germany
    Neurosci Lett 250:5-8. 1998
  4. ncbi request reprint Plasticity of cortical hand muscle representation in patients with hemifacial spasm
    J Liepert
    Department of Neurology, Friedrich Schiller University Jena, Germany
    Neurosci Lett 272:33-6. 1999
  5. ncbi request reprint Mapping plastic brain changes after acute lesions
    J Liepert
    Department of Neurology, Friedrich Schiller University, Jena, Germany
    Curr Opin Neurol 12:709-13. 1999
  6. ncbi request reprint Motor cortex disinhibition in acute stroke
    J Liepert
    Department of Neurology, Friedrich Schiller University, D 07743, Jena, Germany
    Clin Neurophysiol 111:671-6. 2000
  7. ncbi request reprint Treatment-induced cortical reorganization after stroke in humans
    J Liepert
    Department of Neurology, Friedrich Schiller University of Jena, Germany
    Stroke 31:1210-6. 2000
  8. ncbi request reprint Motor cortex excitability after thalamic infarction
    J Liepert
    Department of Neurology, University Hospital Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Clin Neurophysiol 116:1621-7. 2005
  9. ncbi request reprint Interhemispheric effects of high and low frequency rTMS in healthy humans
    A Gorsler
    Department of Neurology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Clin Neurophysiol 114:1800-7. 2003
  10. ncbi request reprint Inhibition of ipsilateral motor cortex during phasic generation of low force
    J Liepert
    Department of Neurology, Friedrich Schiller University Jena, Jena, Germany
    Clin Neurophysiol 112:114-21. 2001

Detail Information

Publications30

  1. ncbi request reprint Motor plasticity induced by synchronized thumb and foot movements
    J Liepert
    Neurologische Universitatsklinik, Friedrich Schiller University, Jena, Germany
    Exp Brain Res 125:435-9. 1999
    ..We conclude that a short-lasting training of synchronous movements induces modulations of motor output maps which probably occur due to interactions between hand and foot representation areas in the motor cortex...
  2. ncbi request reprint Task-dependent changes of intracortical inhibition
    J Liepert
    Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Exp Brain Res 118:421-6. 1998
    ..Additionally, our data further supports the idea that ICI and ICF may be controlled independently...
  3. ncbi request reprint Motor cortex plasticity during constraint-induced movement therapy in stroke patients
    J Liepert
    Department of Neurology, Friedrich Schiller University of Jena, Germany
    Neurosci Lett 250:5-8. 1998
    ..The data therefore demonstrate a CNS correlate of therapy-induced recovery of function after nervous system damage in humans...
  4. ncbi request reprint Plasticity of cortical hand muscle representation in patients with hemifacial spasm
    J Liepert
    Department of Neurology, Friedrich Schiller University Jena, Germany
    Neurosci Lett 272:33-6. 1999
    ..The results indicate activity dependent interactions between hand and face representations in the adult human motor cortex...
  5. ncbi request reprint Mapping plastic brain changes after acute lesions
    J Liepert
    Department of Neurology, Friedrich Schiller University, Jena, Germany
    Curr Opin Neurol 12:709-13. 1999
    ..Recent research focused not only on lesion-induced plasticity, but also on therapy-induced reorganization of the brain. Data from animal experiments has expanded our knowledge of mechanisms that underlie plastic changes...
  6. ncbi request reprint Motor cortex disinhibition in acute stroke
    J Liepert
    Department of Neurology, Friedrich Schiller University, D 07743, Jena, Germany
    Clin Neurophysiol 111:671-6. 2000
    ..To test whether a disinhibition occurs in the human motor cortex after stroke...
  7. ncbi request reprint Treatment-induced cortical reorganization after stroke in humans
    J Liepert
    Department of Neurology, Friedrich Schiller University of Jena, Germany
    Stroke 31:1210-6. 2000
    ..The aim of the present study was to evaluate reorganization in the motor cortex of stroke patients that was induced with an efficacious rehabilitation treatment...
  8. ncbi request reprint Motor cortex excitability after thalamic infarction
    J Liepert
    Department of Neurology, University Hospital Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Clin Neurophysiol 116:1621-7. 2005
    ..We examined 8 patients with hemihypesthesia due to an ischemic thalamic lesion to explore the effects of a central sensory dysfunction on motor cortex excitability...
  9. ncbi request reprint Interhemispheric effects of high and low frequency rTMS in healthy humans
    A Gorsler
    Department of Neurology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Clin Neurophysiol 114:1800-7. 2003
    ..We investigated whether repetitive transcranial magnetic stimulation (rTMS) applied to the right motor cortex modified the excitability of the unstimulated left motor cortex...
  10. ncbi request reprint Inhibition of ipsilateral motor cortex during phasic generation of low force
    J Liepert
    Department of Neurology, Friedrich Schiller University Jena, Jena, Germany
    Clin Neurophysiol 112:114-21. 2001
    ..To study the effect of different types of unilateral pinch grips on excitability of the ipsilateral motor cortex...
  11. ncbi request reprint Modulation of motor cortex excitability induced by pinch grip repetition
    A Gorsler
    Department of Neurology, University Hospital, Hamburg Eppendorf, Germany
    J Neural Transm 111:1005-16. 2004
    ..These changes are distinct and independent of each other. Motor training has an interhemispheric effect on intracortical excitability...
  12. ncbi request reprint Abnormal motor cortex organization contralateral to early upper limb amputation in humans
    C Dettmers
    Neurologie, Friedrich Schiller Universitat, Jena, Germany
    Neurosci Lett 263:41-4. 1999
    ..In addition to previous functional studies, these new structural data suggest that maturation of the central sulcus develops in response to daily practice of the contralateral hand, possibly until adolescence...
  13. ncbi request reprint Disinhibition of somatosensory and motor cortex in mitochondriopathy without myoclonus
    J Liepert
    Department of Neurology, Friedrich Schiller University of Jena, Jena, Germany
    Clin Neurophysiol 112:917-22. 2001
    ..To test electrophysiologically, if patients with mitochondriopathy but without evidence of myocloni have subclinical signs of disinhibition in motor and somatosensory cortices...
  14. ncbi request reprint Motor excitability and motor behaviour after modafinil ingestion--a double-blind placebo-controlled cross-over trial
    J Liepert
    Department of Neurology, University Hospital Eppendorf, Hamburg, Germany
    J Neural Transm 111:703-11. 2004
    ..Thus, this study does not demonstrate significant differences between a single dose of modafinil and placebo in healthy subjects...
  15. ncbi request reprint Motor cortex plasticity during forced-use therapy in stroke patients: a preliminary study
    J Liepert
    Department of Neurology, Friedrich Schiller University, Jena, Germany
    J Neurol 248:315-21. 2001
    ..Due to the small number of patients and the lack of a control group, these results are preliminary observations and require replication in a larger sample...
  16. ncbi request reprint Motor cortex excitability and fatigue in multiple sclerosis: a transcranial magnetic stimulation study
    J Liepert
    Department of Neurology, University Hospital Eppendorf, Hamburg, Germany
    Mult Scler 11:316-21. 2005
    ..We conclude that MS patients with fatigue have an impairment of inhibitory circuits in their primary motor cortex. The results also indicate that fatigue severity is associated with an exercise-induced reduction of membrane excitability...
  17. ncbi request reprint No effect of a levodopa single dose on motor performance and motor excitability in chronic stroke. A double-blind placebo-controlled cross-over pilot study
    C Restemeyer
    Department of Neurology, University Medical Center Eppendorf, Hamburg, Germany
    Restor Neurol Neurosci 25:143-50. 2007
    ..Drugs that modulate neuronal transmission can influence motor recovery after stroke. Here, we tested if a single dose of levodopa could improve motor functions and change motor excitability in a group of chronic stroke patients...
  18. ncbi request reprint Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation
    P Schwenkreis
    Department of Neurology, Buerkle de la Camp Platz 1, Ruhr University Bochum, BG Kliniken Bergmannsheil, 44789 Bochum, Germany
    Exp Brain Res 135:293-9. 2000
    ..The most probable mechanism involves an effect on glutamatergic synaptic transmission...
  19. ncbi request reprint Motor cortex excitability after cerebellar infarction
    J Liepert
    Department of Neurology, University Hospital Eppendorf, Martinistr 52, D 20246 Hamburg, Germany
    Stroke 35:2484-8. 2004
    ..We investigated if the location of a cerebellar infarction was crucial for changes of motor cortex excitability and if the electrophysiological findings were correlated with motor performance...
  20. ncbi request reprint Chronic dose effects of reboxetine on motor skill acquisition and cortical excitability
    R Lange
    Department of Neurology, University Freiburg, Freiburg, Germany
    J Neural Transm 114:1085-9. 2007
    ..In this study, we tested if a chronic dose application of RBX improved motor skill acquisition and modulated cortical excitability...
  21. ncbi request reprint The influence of lorazepam on somatosensory-evoked fast frequency (600 Hz) activity in MEG
    J Haueisen
    Department of Neurology, Biomagnetisches Zentrum, Friedrich Schiller Universitat Jena, Philosophenweg 3, 07740, Jena, Germany
    Brain Res 874:10-4. 2000
    ..The source strengths of both N20m and 600-Hz bursts were significantly increased. Our results provide evidence for two components of the 600-Hz activity with a different generator structure...
  22. ncbi request reprint Motor cortex disinhibition in Alzheimer's disease
    J Liepert
    Department of Neurology, Friedrich Schiller University, Jena, Germany
    Clin Neurophysiol 112:1436-41. 2001
    ..To explore subclinical disturbances in the motor cortex of patients with Alzheimer's disease (AD)...
  23. ncbi request reprint Structural and functional cortical abnormalities after upper limb amputation during childhood
    F Hamzei
    Department of Neurology, Friedrich-Schiller-University, Jena, Germany
    Neuroreport 12:957-62. 2001
    ..Therefore, arm amputation in childhood affects functional organization as well as anatomical structure in both hemispheres...
  24. ncbi request reprint Orally administered atropine enhances motor cortex excitability: a transcranial magnetic stimulation study in human subjects
    J Liepert
    Department of Neurology, Friedrich Schiller University, Jena, Germany
    Neurosci Lett 300:149-52. 2001
    ..Thus, an antagonist of pre- and postsynaptic muscarinic receptors increased excitability in the human motor cortex in a dose-dependent manner, indicating an influence of the cholinergic system on motor cortex excitation...
  25. pmc Motor system abnormalities in hereditary spastic paraparesis type 4 (SPG4) depend on the type of mutation in the spastin gene
    D Bonsch
    Institut für Klinische Chemie und Laboratoriumsdiagnostik, Universitatsklinikum Jena, D 07740 Jena, Germany
    J Neurol Neurosurg Psychiatry 74:1109-12. 2003
    ..A variety of mutations have been identified within the SPG4 gene product, spastin...
  26. ncbi request reprint [Repetitive transcranial magnetic stimulation (rTMS) in the acute and long-term therapy of refractory depression--a case report]
    S Smesny
    Klinik für Psychiatrie der Friedrich Schiller Universität Jena, Philosophenweg 3, 07740 Jena
    Nervenarzt 72:734-8. 2001
    ..The rTMS treatments and psychotherapeutic counseling have been continued on an outpatient basis. Thus, pharmaco- and psychotherapeutic interventions combined with rTMS led to persistent symptom remission and social reintegration...
  27. ncbi request reprint Lesion-induced and training-induced brain reorganization
    J Liepert
    Department of Neurology, University Hospital Eppendorf, D 20246 Hamburg, Germany
    Restor Neurol Neurosci 22:269-77. 2004
    ..We examined if distinct ischemic brain lesions are associated with a specific pattern of excitability changes. We also investigated the effects of a rehabilitative therapy on motor excitability...
  28. ncbi request reprint Transcranial magnetic stimulation in neurorehabilitation
    J Liepert
    Department of Neurology, University Hospital Eppendorf, Hamburg, Germany
    Acta Neurochir Suppl 93:71-4. 2005
    ..Some evidence is emerging that the application of low frequency repetitive TMS over the non-lesioned hemisphere improves neglect phenomena by down-regulation of the excitability of the non-lesioned hemisphere...
  29. ncbi request reprint Fatigue suppresses ipsilateral intracortical facilitation
    T Baumer
    Department of Neurology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany
    Exp Brain Res 146:467-73. 2002
    ..These results indicate interhemispheric interactions between the two motor cortices that are still effective after cessation of movements...
  30. pmc Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFE
    Hans Christoph Diener
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Lancet Neurol 7:875-84. 2008
    ..The putative neuroprotective effects of antiplatelet compounds and the angiotensin II receptor antagonist telmisartan were investigated in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial...