Research Topics
Species | F KuetheSummaryAffiliation: Friedrich Schiller University Country: Germany Publications
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Detail Information
Publications
Immunopathogenesis of dilated cardiomyopathy. Evidence for the role of TH2-type CD4+T lymphocytes and association with myocardial HLA-DR expressionFriedhelm Kuethe
Klinik fuer Innere Medizin I, Friedrich Schiller Universitaet Jena, Erlanger Allee 101, Jena, 07740, Germany
J Clin Immunol 26:33-9. 2006..In the present study, we investigated the relation between the peripheral CD4+T-cell subset and the degree of HLA expression in the heart...
Lack of regeneration of myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans with large anterior myocardial infarctionsFriedhelm Kuethe
Klinik fuer Innere Medizin I, Friedrich Schiller Universitaet Jena, Erlanger Allee 101, 07740 Jena, Germany
Int J Cardiol 97:123-7. 2004..This approach should be tested in patients with large infarctions in whom a positive effect would be most beneficial...
Detection of viral genome in the myocardium: lack of prognostic and functional relevance in patients with acute dilated cardiomyopathyFriedhelm Kuethe
Klinik fuer Innere Medizin I, Friedrich Schiller Universitaet Jena, Jena, Germany
Am Heart J 153:850-8. 2007..This study was undertaken to determine if the detection of viral genome in the myocardium of patients with DCM is of functional and prognostic relevance under modern treatment strategies of heart insufficiency...
Autologous intracoronary mononuclear bone marrow cell transplantation in chronic ischemic cardiomyopathy in humansFriedhelm Kuethe
Klinik fuer Innere Medizin I, Friedrich Schiller University of Jena, Erlanger Allee 101, 07740 Jena, Germany
Int J Cardiol 100:485-91. 2005..We hypothesized that patients with chronic ischemic cardiomyopathy could also benefit from autologous BMC transplantation in addition to established heart failure therapy...
Treatment with granulocyte colony-stimulating factor for mobilization of bone marrow cells in patients with acute myocardial infarctionFriedhelm Kuethe
Klinik fuer Innere Medizin I, Friedrich Schiller Universitaet Jena, Jena, Germany
Am Heart J 150:115. 2005....
Creatine supplementation improves muscle strength in patients with congestive heart failureF Kuethe
Klinik fur Innere Medizin I, Friedrich Schiller Universitaet, Jena, Germany
Pharmazie 61:218-22. 2006..We therefore hypothesized that oral creatine supplementation improves skeletal muscle strength, quality of live and symptom-limited performance in patients with CHF...
Treatment with granulocyte-colony stimulating factor in patients with acute myocardial infarction. Evidence for a stimulation of neovascularization and improvement of myocardial perfusionF Kuethe
, MD, , , Erlanger Allee 101, D-07740 Jena, Germany
Pharmazie 61:957-61. 2006..CONCLUSION: In patients with AMI, the treatment with G-CSF modulates the formation of vascular growth factors that might improve neovascularization and result in an improved myocardial perfusion and function...
[Mobilization of stem cells by granulocyte colony-stimulating factor for the regeneration of myocardial tissue after myocardial infarction]F Kuethe
Klinik fur Innere Medizin I, Freiedrich Schiller Universität, Jena
Dtsch Med Wochenschr 129:424-8. 2004..We analysed cardiac function and perfusion in 5 patients who were treated with G-CSF in addition to standard therapeutical regimen...
Apoptosis in patients with dilated cardiomyopathy and diabetes: a feature of diabetic cardiomyopathy?F Kuethe
Klinik fur Innere Medizin I, Friedrich Schiller Universitat Jena, Jena, Germany
Horm Metab Res 39:672-6. 2007....
Cardiotrophin-1 induces monocyte chemoattractant protein-1 synthesis in human umbilical vein endothelial cellsMichael Fritzenwanger
Department of Internal Medicine I, Division of Cardiology, Friedrich Schiller University Jena, Erlanger Allee 101, 07740 Jena, Germany
Cytokine 33:46-51. 2006..In CHF, CT-1 may be able to induce MCP-1 which might be responsible for progression of heart failure either by recruiting inflammatory cells within the myocardium or by a direct modulation of myocyte function...
Collaterals and the recovery of left ventricular function after recanalization of a chronic total coronary occlusionGerald S Werner
Clinic for Internal Medicine I, Friedrich Schiller University Jena, Jena, Germany
Am Heart J 149:129-37. 2005..A good collateral function in patients with regional myocardial dysfunction may indicate viability with the potential for left ventricular (LV) recovery after revascularization of a chronic total coronary occlusion (CTO)...
Cardiotrophin-1 induces interleukin-6 synthesis in human umbilical vein endothelial cellsMichael Fritzenwanger
Department of Internal Medicine I, Division of Cardiology, Friedrich Schiller University Jena, Erlanger Allee 101, 07740 Jena, Germany
Cytokine 36:101-6. 2006..We speculate that in CHF CT-1 might be in part responsible for increased IL-6 plasma concentrations. Modulation of the CT-1 pathway may be a further strategy in CHF treatment...
Growth factors in the collateral circulation of chronic total coronary occlusions: relation to duration of occlusion and collateral functionGerald S Werner
Clinic for Internal Medicine I, Friedrich Schiller University Jena, Jena, Germany
Circulation 110:1940-5. 2004..Despite extensive animal experimental evidence, there are few data on the relation of growth factors and collateral function in humans...
Cardiotrophin-1 induces interleukin-6 synthesis in human monocytesMichael Fritzenwanger
Department of Internal Medicine I, Division of Cardiology, Friedrich Schiller University Jena, Erlanger Allee 101, 07740 Jena, Germany
Cytokine 38:137-44. 2007..Additionally, monocyte function is modulated in CHF. The aim of this study was to examine if CT-1 is able to induce IL-6 in human monocytes and to investigate the underlying pathway...
Angiographic assessment of collateral connections in comparison with invasively determined collateral function in chronic coronary occlusionsGerald S Werner
Clinic for Internal Medicine III, Friedrich Schiller University Jena, Jena, Germany
Circulation 107:1972-7. 2003....
