Affiliation: Friedrich Schiller University
- Effect of quality characteristics of single sample preparation steps in the precision and coverage of proteomic studies--a reviewThomas Krüger
Institute of Biochemistry I, Nonnenplan 2, Universitatsklinikum Jena, 07740 Jena, Germany
Anal Chim Acta 776:1-10. 2013....
- Proteome analysis of body fluids for amyotrophic lateral sclerosis biomarker discoveryThomas Krüger
Institute of Biochemistry 1, University Hospital, Jena, Germany
Proteomics Clin Appl 7:123-35. 2013..Furthermore, limitations and advantages of proteomic approaches for ALS biomarker discovery in different body fluids and reliable validation of biomarker candidates have been addressed...
- The removal of Triton X-100 by dialysis is feasible!Stefan Opitz
Institute of Biochemistry I, Jena University Hospital, Nonnenplan 2, 07743, Jena, Germany
Anal Bioanal Chem 407:1107-18. 2015..Applicability and protocols are shown with proteomic sample preparation of purified proteins and complex protein mixtures prior to matrix-assisted laser desorption ionization (MALDI) mass spectrometry. ..
- Native chromatographic sample preparation of serum, plasma and cerebrospinal fluid does not comprise a risk for proteolytic biomarker lossJelena Pesek
Institute of Biochemistry I, Universitatsklinikum Jena, Jena, Germany
J Chromatogr B Analyt Technol Biomed Life Sci 923:102-9. 2013..These results suggest that intrinsic, native proteinase inhibitors potentially protect the proteomes considered, enabling “top-down” proteomic approaches under native conditions with serum, plasma and cerebrospinal fluid...