Research Topics
| Andreas KrackSummaryAffiliation: Friedrich Schiller University Country: Germany Publications
| Collaborators |
Detail Information
Publications
Studies on intragastric PCO2 at rest and during exercise as a marker of intestinal perfusion in patients with chronic heart failureAndreas Krack
Department of Cardiology, Friedrich Schiller University, Erlanger Allee 101, D 07740, Jena, Germany
Eur J Heart Fail 6:403-7. 2004..In CHF inflammatory immune activation is hypothesized to result from a chronic endotoxin challenge due to bacterial translocation of hypoperfused intestinal mucosa...- The importance of the gastrointestinal system in the pathogenesis of heart failureAndreas Krack
Clinical Cardiology, NHLI, Imperial College School of Medicine, London, UK
Eur Heart J 26:2368-74. 2005..It is hoped that by improving our understanding of the role of the gut in cardiac disease will lead to the development of novel therapeutic strategies in the future... - Paclitaxel-eluting stents for the treatment of chronic total coronary occlusions: a strategy of extensive lesion coverage with drug-eluting stentsGerald S Werner
Clinic for Internal Medicine I, Friedrich Schiller University Jena, Erlanger Allee 101, D 07740 Jena, Germany
Catheter Cardiovasc Interv 67:1-9. 2006..However, diffuse atherosclerosis in CTOs should be covered completely by the drug-eluting stents... - Prevention of lesion recurrence in chronic total coronary occlusions by paclitaxel-eluting stentsGerald S Werner
Clinic for Internal Medicine I, Friedrich-Schiller University Jena, Jena, Germany
J Am Coll Cardiol 44:2301-6. 2004..Chronic total coronary occlusion should be a preferred indication for drug-eluting stents... - Analysis of location and pattern of target vessel failure in chronic total occlusions after stent implantation and its potential for the efficient use of drug-eluting stentsStefan Betge
Department of Cardiology, Friedrich Schiller University, Jena, Germany
J Interv Cardiol 19:226-31. 2006..Little is known about the localization of lesion recurrence, and whether extensive stenting should be performed. In this prospective analysis, the area at high risk for restenoses after recanalization of CTO was localized... - Cardiotrophin-1 induces interleukin-6 synthesis in human monocytesMichael Fritzenwanger
Department of Internal Medicine I, Division of Cardiology, Friedrich Schiller University Jena, Erlanger Allee 101, 07740 Jena, Germany
Cytokine 38:137-44. 2007..Additionally, monocyte function is modulated in CHF. The aim of this study was to examine if CT-1 is able to induce IL-6 in human monocytes and to investigate the underlying pathway... - No association between transmembrane protein-tyrosine phosphatase receptor type C (CD45) exon A point mutation (77C>G) and idiopathic dilated cardiomyopathyHansjörg Thude
Institute for Transfusion Medicine, University Hospital of Jena, Jena, Germany
Hum Immunol 66:1008-12. 2005..3% found in the control group (p=0.327). In conclusion, the data of this preliminary study could not reveal any association between the CD45 77C>G polymorphism and susceptibility to idiopathic DCM in a German population... 
Iohexol contrast medium induces QT prolongation in amiodarone patientsMatthias Goernig
Friedrich Schiller University, Clinic of Internal Medicine III, Erlanger Allee 101, D 07740 Jena, Germany
Br J Clin Pharmacol 58:96-8. 2004..Amiodarone is widely used in ventricular tachyarrhythmias and atrial fibrillation, known to prolong QT-intervals. Concurrent administration of drugs prolonging QT- time can induce life-threatening ventricular tachyarrhythmia...- Improvement of the primary success rate of recanalization of chronic total coronary occlusions with the Safe-Cross system after failed conventional wire attemptsGerald S Werner
Medizinische Klinik I, Klinikum Darmstadt, Grafenstrasse 9, 64283 Darmstadt, Germany
Clin Res Cardiol 96:489-96. 2007..The goal of the present study was to determine the additional benefit of a new penetration device in CTOs after an extensive conventional wire approach... 
Reduced glucose transporter GLUT4 in skeletal muscle predicts insulin resistance in non-diabetic chronic heart failure patients independently of body compositionWolfram Doehner
Division of Applied Cachexia Research, Department of Cardiology, Charite, Campus Virchow Klinikum, Berlin, Germany
Int J Cardiol 138:19-24. 2010..GLUT4, the predominant glucose transporter in the skeletal muscle promotes the rate-limiting step of glucose utilization in skeletal muscle. The significance of skeletal muscle GLUT4 in patients with CHF has not been studied in detail...- Outcome after cardiac arrest: predictive values and limitations of the neuroproteins neuron-specific enolase and protein S-100 and the Glasgow Coma ScaleRüdiger Pfeifer
Department of Internal Medicine I, Division of Cardiology and Intensive Care Medicine, University of Jena, Erlanger Allee 101, D 07740 Jena, Germany
Resuscitation 65:49-55. 2005.... - Sirolimus-eluting stents for the prevention of restenosis in a worst-case scenario of diffuse and recurrent in-stent restenosisGerald S Werner
Clinic for Internal Medicine III, Friedrich Schiller University Jena, Jena, Germany
Catheter Cardiovasc Interv 63:259-64. 2004..The observed restenosis rate is lower than that reported after brachytherapy and suggests that sirolimus-eluting stents are a promising treatment option for ISR... - Cardiotrophin-1 induces interleukin-6 synthesis in human umbilical vein endothelial cellsMichael Fritzenwanger
Department of Internal Medicine I, Division of Cardiology, Friedrich Schiller University Jena, Erlanger Allee 101, 07740 Jena, Germany
Cytokine 36:101-6. 2006..We speculate that in CHF CT-1 might be in part responsible for increased IL-6 plasma concentrations. Modulation of the CT-1 pathway may be a further strategy in CHF treatment... - Treatment with granulocyte colony-stimulating factor for mobilization of bone marrow cells in patients with acute myocardial infarctionFriedhelm Kuethe
Klinik fuer Innere Medizin I, Friedrich Schiller Universitaet Jena, Jena, Germany
Am Heart J 150:115. 2005.... - Growth factors in the collateral circulation of chronic total coronary occlusions: relation to duration of occlusion and collateral functionGerald S Werner
Clinic for Internal Medicine I, Friedrich Schiller University Jena, Jena, Germany
Circulation 110:1940-5. 2004..Despite extensive animal experimental evidence, there are few data on the relation of growth factors and collateral function in humans... - Carvedilol inhibits platelet-derived growth factor-induced signal transduction in human cardiac fibroblastsUlrich Lotze
Department of Internal Medicine I Cardiology, Angiology, Pneumology, Hospital Waltershausen Friedrichroda, Reinhardsbrunner Strasse 14 17, D 99894 Friedrichroda, Germany
J Cardiovasc Pharmacol 39:576-89. 2002..These findings provide novel experimental support for the known beneficial clinical effects of carvedilol in the treatment of chronic heart failure associated with myocardial fibrosis...