Research Topics
| Martin Johannes KoehlerSummaryAffiliation: Friedrich Schiller University Country: Germany Publications
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Detail Information
Publications
Non-invasive imaging techniques in the diagnosis of skin diseasesMartin Johannes Koehler
University Hospital Jena, Department of Dermatology, Erfurter Str 35, 07743 Jena, Germany 49 3641 9 37370 49 3641 9 37343
Expert Opin Med Diagn 5:425-40. 2011..Future research will not only aim at improving current technical limitations, but also investigate the potential synergistic effects of combining two or more techniques in order to enhance their diagnostic impact...
Non-invasive evaluation of dermal elastosis by in vivo multiphoton tomography with autofluorescence lifetime measurementsMartin J Koehler
Department of Dermatology, University Hospital Jena, Jena, Germany
Exp Dermatol 21:48-51. 2012..The FLIM analyses have shown that dermal autofluorescence has different lifetimes depending on age and in part on localization...
Clinical application of multiphoton tomography in combination with confocal laser scanning microscopy for in vivo evaluation of skin diseasesMartin Johannes Koehler
Department of Dermatology, University Hospital Jena, Jena, Germany
Exp Dermatol 20:589-94. 2011..Synergies of the combination of CLSM and MPT may be obtained by combined implementation in order to benefit from the fast overview given by CLSM and the detailed imaging of skin structures by MPT...
Keratinocyte morphology of human skin evaluated by in vivo multiphoton laser tomographyM J Koehler
Department of Dermatology, University Hospital Jena, Jena, Germany
Skin Res Technol 17:479-86. 2011....
In vivo measurement of the human epidermal thickness in different localizations by multiphoton laser tomographyMartin Johannes Koehler
Department of Dermatology and Allergology, Friedrich Schiller University, Jena, Germany
Skin Res Technol 16:259-64. 2010..While ultrasound, optical coherence tomography and confocal laser microscopy are used with moderate success, this issue has not been addressed by multiphoton laser tomography...
Actinic damage and its treatmentsM J Koehler
Department of Dermatology, University Hospital Jena, Jena, Germany
G Ital Dermatol Venereol 145:175-85. 2010..This review will focus on 1) the basic principles of actinic damage including carcinogenesis; 2) treatment options for photoaged skin and 3) an overview of current therapy concepts of light induced skin tumours...
Intrinsic, solar and sunbed-induced skin aging measured in vivo by multiphoton laser tomography and biophysical methodsMartin Johannes Koehler
Department of Dermatology and Allergology, Friedrich Schiller University, Jena 07743, Germany
Skin Res Technol 15:357-63. 2009..Over the last decades, both clinical and pathological differences between intrinsic and actinic aging have been characterized. In this work, we aimed at quantifying skin aging by non-invasive in vivo methods...
In vivo assessment of human skin aging by multiphoton laser scanning tomographyMartin Johannes Koehler
Department of Dermatology and Allergology, Freidrich Schiller University, Jena, Germany
Opt Lett 31:2879-81. 2006....
Sensitivity and specificity of multiphoton laser tomography for in vivo and ex vivo diagnosis of malignant melanomaEnrico Dimitrow
Department of Dermatology and Allergology, University of Jena, Jena, Germany
J Invest Dermatol 129:1752-8. 2009..By means of this procedure accuracy values up to 97% were reached. These findings underline the potential applicability of multiphoton laser tomography in melanoma diagnosis of melanocytic skin lesions...
Morphological skin ageing criteria by multiphoton laser scanning tomography: non-invasive in vivo scoring of the dermal fibre networkMartin Johannes Koehler
Department of Dermatology and Allergology, Friedrich Schiller University, Jena, Germany
Exp Dermatol 17:519-23. 2008..Morphological changes in the dermal collagen and elastin fibre network are characteristic for skin ageing and for pathological skin conditions of the dermis...
Depth-resolved measurement of the dermal matrix composition by multiphoton laser tomographyMartin Kaatz
Department of Dermatology and Allergology, University Hospital, Jena, Germany
Skin Res Technol 16:131-6. 2010....
Spectral fluorescence lifetime detection and selective melanin imaging by multiphoton laser tomography for melanoma diagnosisEnrico Dimitrow
Department of Dermatology and Allergology, University Hospital, Jena, Germany
Exp Dermatol 18:509-15. 2009..Procedures of selective imaging as well as spectral fluorescence lifetime imaging by means of multiphoton laser tomography support diagnostic decisions and may improve the process of non-invasive early detection of melanoma...
Changes in skin topography during hormone therapyMartin Kaatz
Department of Dermatology and Allergology, Friedrich Schiller University, Jena, Germany
Menopause 15:1193-4. 2008..In our study, the skin roughness of eight women receiving hormone therapy decreased significantly by approximately 15% in 12 months. Our results provide new evidence of the antiaging effect of female sex hormones...
An unusual histologic variant of necrobiotic xanthogranulomaMirjana Ziemer
Department of Dermatology, Venereology, and Allergology, University Hospital of Leipzig, Philipp Rosenthal Str 23 25, Leipzig, Germany
Am J Dermatopathol 34:e22-6. 2012..Moreover, the case shows overlaps with recently published granulomatous scleromyxedema. Some common clinical and histopathologic features of NXG and scleromyxedema might be based on shared underlying paraproteinemia...
Erythema elevatum diutinum - a chronic leukocytoclastic vasculitis microscopically indistinguishable from granuloma faciale?Mirjana Ziemer
Department of Dermatology, Venereology, and Allergology, University Hospital of Leipzig, Leipzig, Germany
J Cutan Pathol 38:876-83. 2011..As the sequential inflammatory changes are the same in erythema elevatum diutinum (EED) and granuloma faciale (GF), histopathologic distinction may be difficult...
