Friedemann Gaube

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. doi request reprint Effects of Leuzea carthamoides on human breast adenocarcinoma MCF-7 cells determined by gene expression profiling and functional assays
    Friedemann Gaube
    Institute of Pharmacy, University of Jena, Jena, Germany
    Planta Med 74:1701-8. 2008
  2. doi request reprint Antimicrobial, antiproliferative, cytotoxic, and tau inhibitory activity of rubellins and caeruleoramularin produced by the phytopathogenic fungus Ramularia collo-cygni
    Sebastian Miethbauer
    Institute of Pharmacy, University of Jena, Jena, Germany
    Planta Med 75:1523-5. 2009
  3. pmc Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7
    Friedemann Gaube
    Institute of Pharmacy, Department of Pharmaceutical Biology, University of Jena, Semmelweisstr, 10, 07743 Jena, Germany
    BMC Pharmacol 7:11. 2007

Collaborators

  • Matthias Hamburger
  • Sebastian Miethbauer
  • Bernd Liebermann
  • Manfred Gareis
  • Michaela Schmidtke
  • Ute Möllmann
  • Hans Martin Dahse
  • Marcus Pickhardt

Detail Information

Publications3

  1. doi request reprint Effects of Leuzea carthamoides on human breast adenocarcinoma MCF-7 cells determined by gene expression profiling and functional assays
    Friedemann Gaube
    Institute of Pharmacy, University of Jena, Jena, Germany
    Planta Med 74:1701-8. 2008
    ..Leuzea extract also inhibited 5alpha-reductase, type II. While the extract significantly modulates cellular activities, the phytoecdysteroids, are most likely not the active principles of L. carthamoides...
  2. doi request reprint Antimicrobial, antiproliferative, cytotoxic, and tau inhibitory activity of rubellins and caeruleoramularin produced by the phytopathogenic fungus Ramularia collo-cygni
    Sebastian Miethbauer
    Institute of Pharmacy, University of Jena, Jena, Germany
    Planta Med 75:1523-5. 2009
    ..Furthermore, when tested without illumination, compounds exerted antiproliferative and cytotoxic activity in a series of human tumor cell lines. Inhibition of tau protein assembly was observed as well...
  3. pmc Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7
    Friedemann Gaube
    Institute of Pharmacy, Department of Pharmaceutical Biology, University of Jena, Semmelweisstr, 10, 07743 Jena, Germany
    BMC Pharmacol 7:11. 2007
    ..We, therefore, investigated the effects of a lipophilic black cohosh rhizome extract and cycloartane-type triterpenoids on the estrogen receptor positive human breast cancer cell line MCF-7...