Jens Dawczynski

Summary

Affiliation: Friedrich Schiller University
Country: Germany

Publications

  1. doi Simple and objective method for routine detection of the macular pigment xanthophyll
    Dietrich Schweitzer
    Augenklinik der Friedrich Schiller Universität Jena, Experimentelle Ophthalmologie Bachstrasse 18 07743 Jena, Germany
    J Biomed Opt 15:061714. 2010
  2. doi Ultrastructure of the membrana limitans interna after dye-assisted membrane peeling
    Tobias Brockmann
    Department of Ophthalmology, Electron Microscopy Center, University Hospital Jena, Jena, Germany
    Ophthalmologica 226:228-33. 2011
  3. ncbi Advanced glycation end-products in corneas of patients with keratoconus
    Jens Dawczynski
    Department of Ophthalmology, Friedrich Schiller University Jena, Bachstrasse 18, 07740 Jena, Germany
    Graefes Arch Clin Exp Ophthalmol 240:296-301. 2002
  4. ncbi [Selenium and cataract--risk factor or useful dietary supplement?]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, 07743 Jena
    Klin Monbl Augenheilkd 223:675-80. 2006
  5. ncbi [Histological and immunohistological investigations in human epiretinal membranes]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, 07743 Jena
    Klin Monbl Augenheilkd 223:687-90. 2006
  6. ncbi [Advanced glycation end products and pseudoexfoliation--correlation between clinical outcome and histological findings]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena
    Klin Monbl Augenheilkd 223:748-51. 2006
  7. ncbi Interdisciplinary treatment and ophthalmological findings in Parry-Romberg syndrome
    Jens Dawczynski
    Department of Ophthalmology, University Hospital Jena, Jena, Germany
    J Craniofac Surg 17:1175-6. 2006
  8. doi Determination of absolute size of fundus objects
    Jens Dawczynski
    Department of Ophthalmology, University Hospital Jena, Bachstr 18, 07749 Bachstraße 18, 07740, Jena, Germany
    Graefes Arch Clin Exp Ophthalmol 249:381-7. 2011
  9. ncbi Anterior segment optical coherence tomography for evaluation of changes in anterior chamber angle and depth after intraocular lens implantation in eyes with glaucoma
    J Dawczynski
    Department of Ophthalmology, University Hospital Jena, Jena, Germany
    Eur J Ophthalmol 17:363-7. 2007
  10. ncbi [Endothelial dysfunction of central retinal vessels: a prognostic parameter for diabetic retinopathy?]
    J Dawczynski
    Universitats Augenklinik, Klinikum der FSU Jena
    Klin Monbl Augenheilkd 224:827-31. 2007

Collaborators

Detail Information

Publications37

  1. doi Simple and objective method for routine detection of the macular pigment xanthophyll
    Dietrich Schweitzer
    Augenklinik der Friedrich Schiller Universität Jena, Experimentelle Ophthalmologie Bachstrasse 18 07743 Jena, Germany
    J Biomed Opt 15:061714. 2010
    ..610±0.093 ODU) than in healthy subjects (n = 45) (ODx = 0.674±0.098 ODU) (p = 0.00019). No dependence on age was found in the pseudophakic eyes both of healthy subjects and AMD patients...
  2. doi Ultrastructure of the membrana limitans interna after dye-assisted membrane peeling
    Tobias Brockmann
    Department of Ophthalmology, Electron Microscopy Center, University Hospital Jena, Jena, Germany
    Ophthalmologica 226:228-33. 2011
    ..A possible explanation might be seen in the known photosensitivity of ICG, which induces a stiffening and shrinkage of the ILM but also generates retinal toxic metabolites...
  3. ncbi Advanced glycation end-products in corneas of patients with keratoconus
    Jens Dawczynski
    Department of Ophthalmology, Friedrich Schiller University Jena, Bachstrasse 18, 07740 Jena, Germany
    Graefes Arch Clin Exp Ophthalmol 240:296-301. 2002
    ..The underlying mechanisms are still not clear. One possible pathway is increased formation and accumulation of advanced glycation end-products (AGEs) in the cornea...
  4. ncbi [Selenium and cataract--risk factor or useful dietary supplement?]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, 07743 Jena
    Klin Monbl Augenheilkd 223:675-80. 2006
    ..Both protective and toxic effects and mechanisms have been postulated in the past. Accordingly, the selenium contents in human lenses and blood sera in different forms of cataract were investigated...
  5. ncbi [Histological and immunohistological investigations in human epiretinal membranes]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, 07743 Jena
    Klin Monbl Augenheilkd 223:687-90. 2006
    ..This study aimed to investigate human epiretinal membranes with the help of different histological and immunohistological methods in order to find new concepts for the development of these membranes...
  6. ncbi [Advanced glycation end products and pseudoexfoliation--correlation between clinical outcome and histological findings]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena
    Klin Monbl Augenheilkd 223:748-51. 2006
    ..This study investigated for the first time immunohistochemically lens capsules of PXS patients for the AGE carboxymethylysine (CML) and correlated the findings with the clinical outcome of the patients...
  7. ncbi Interdisciplinary treatment and ophthalmological findings in Parry-Romberg syndrome
    Jens Dawczynski
    Department of Ophthalmology, University Hospital Jena, Jena, Germany
    J Craniofac Surg 17:1175-6. 2006
    ..In the presented case of Parry-Romberg syndrome a rare association to ophthalmological involvement could be found. Beside the enophthalmos and eyelid alterations, also a panuveitis with papillitis should be treated by steroid therapy...
  8. doi Determination of absolute size of fundus objects
    Jens Dawczynski
    Department of Ophthalmology, University Hospital Jena, Bachstr 18, 07749 Bachstraße 18, 07740, Jena, Germany
    Graefes Arch Clin Exp Ophthalmol 249:381-7. 2011
    ..Creating multiple beam interference fringes on the retina using the "retina fringe projector" (RFP) provides us with a scale which can be used to determine the absolute size of objects at the fundus...
  9. ncbi Anterior segment optical coherence tomography for evaluation of changes in anterior chamber angle and depth after intraocular lens implantation in eyes with glaucoma
    J Dawczynski
    Department of Ophthalmology, University Hospital Jena, Jena, Germany
    Eur J Ophthalmol 17:363-7. 2007
    ..To examine anterior chamber depth (ACD) and anterior chamber angle (ACA) in patients with glaucoma after cataract extraction with an anterior optical coherence tomography (OCT) system...
  10. ncbi [Endothelial dysfunction of central retinal vessels: a prognostic parameter for diabetic retinopathy?]
    J Dawczynski
    Universitats Augenklinik, Klinikum der FSU Jena
    Klin Monbl Augenheilkd 224:827-31. 2007
    ..Flicker-induced endothelial NO release may be used as an indicator for endothelial functionality of the central retinal vessels...
  11. doi [Objective measurement of macular optical density]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, Jena
    Klin Monbl Augenheilkd 228:57-61. 2011
    ..The 1-wavelength reflection method is used for the newly initiated LUTEGA study. This study will investigate the long-term effects of a fixed lutein/omega-3-fatty acid combination on the optical density in patients with dry AMD...
  12. ncbi Anterior optical coherence tomography: a non-contact technique for anterior chamber evaluation
    Jens Dawczynski
    University Eye Hospital Jena, Bachstrasse 18, 07743, Jena, Germany
    Graefes Arch Clin Exp Ophthalmol 245:423-5. 2007
    ..To assess a new non-contact anterior optical coherence tomography (OCT) system for anterior chamber evaluation...
  13. ncbi [The aging lens--new concepts for lens aging]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, 07743 Jena
    Ophthalmologe 103:759-64. 2006
    ..Advanced glycation end-products and their potential inhibition seem to play a key role...
  14. ncbi [Unilateral protrusion of the eyeball. A 21-year-old patient with a 3-week painless right-sided protrusion of the eyeball]
    J Dawczynski
    Klinik fur Augenheilkunde, Universitatsklinikum, Jena
    Ophthalmologe 102:86-8. 2005
  15. ncbi [Preretinal haemorrhage after vomiting--a case report]
    Jens Dawczynski
    Universitatsklinikum Jena, Klinik fur Augenheilkunde
    Klin Monbl Augenheilkd 221:125-7. 2004
    ..There are different therapeutical options for treating early preretinal hemorrhages. Beside surgery and intraocular drug administration some reports have been published using neodymium-YAG laser...
  16. doi Retinal venous oxygen saturation increases by flicker light stimulation
    Martin Hammer
    Department of Ophthalmology, University of Jena, Jena, Germany
    Invest Ophthalmol Vis Sci 52:274-7. 2011
    ..Oxygen supply may be the target of the regulation of retinal blood flow. Thus, the oxygen saturation (SO(2)) in retinal arterioles and venules was investigated along with their diameters...
  17. doi Abnormal retinal autoregulation is detected by provoked stimulation with flicker light in well-controlled patients with type 1 diabetes without retinopathy
    Aleksandra Mandecka
    Department of Internal Medicine III, Friedrich Schiller University, Jena, Germany
    Diabetes Res Clin Pract 86:51-5. 2009
    ..We investigated whether dynamic analysis apart from the static one in type 1 diabetic patients without diabetic retinopathy with well-controlled diabetes could lead to additional information regarding retinal autoregulation...
  18. doi Retinal vessel oxygen saturation under flicker light stimulation in patients with nonproliferative diabetic retinopathy
    Martin Hammer
    Department of Ophthalmology, University of Jena, Jena, Germany
    Invest Ophthalmol Vis Sci 53:4063-8. 2012
    ..We investigated the response of retinal vessel diameters and oxygen saturation to flicker light stimulation of neuronal activity in patients with diabetic retinopathy...
  19. ncbi Increased levels of advanced glycation end products in human cataractous lenses
    Sybille Franke
    Department of Internal Medicine III, Friedrich Schiller University of Jena, 07740 Jena, Germany
    J Cataract Refract Surg 29:998-1004. 2003
    ....
  20. doi Photodynamic properties of vital dyes for vitreoretinal surgery
    Tobias Brockmann
    Department of Ophthalmology, Charite University Medicine Berlin, Berlin, Germany
    Ophthalmologica 228:234-8. 2012
    ..For this reason, our study provides evidence that intraocular dye concentrations and modern endoillumination systems alone cannot fully prevent ICG photodegradation...
  21. doi Diabetic patients with retinopathy show increased retinal venous oxygen saturation
    Martin Hammer
    Department of Ophthalmology, University of Jena, Bachstr 18, 07740, Jena, Germany
    Graefes Arch Clin Exp Ophthalmol 247:1025-30. 2009
    ..Longstanding diabetes mellitus results in a disturbed microcirculation. A new imaging oximeter was used to investigate the effect of this disturbance on retinal vessel oxygen saturation...
  22. ncbi Advanced glycation end-products in anterior chamber aqueous of cataractous patients
    Sybille Franke
    Department of Internal Medicine IV, University of Jena, Jena, Germany
    J Cataract Refract Surg 29:329-35. 2003
    ....
  23. doi Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study
    Jens Dawczynski
    Department of Ophthalmology, University Hospital Leipzig, Liebigstrasse 10 14, 04103, Leipzig, Germany
    Graefes Arch Clin Exp Ophthalmol 251:2711-23. 2013
    ....
  24. doi Macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration: a randomized trial
    Christin Arnold
    Bioactive Plant Products Research Group, Institute of Nutrition, Friedrich Schiller University Jena, Jena, Germany
    JAMA Ophthalmol 131:564-72. 2013
    ..Additionally, ω-3 long-chain polyunsaturated fatty acids (LC-PUFAs) may also be protective...
  25. doi [Corneal ulcers in systemic autoimmunologic diseases]
    R Augsten
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, Jena
    Klin Monbl Augenheilkd 228:66-9. 2011
    ..Keratolysis is a rare severe complication following systemic autoimmunologic diseases. Despite of complex therapeutic treatments, the prognosis is very poor...
  26. ncbi [Listeria monocytogenes endophthalmitis]
    R Augsten
    Klinik für Augenheilkunde der Friedrich Schiller Universität Jena
    Klin Monbl Augenheilkd 221:1054-6. 2004
    ..Controversy exists concerning clinical progress and prognosis in this bacterial infection. However, only a few reports about the clinical features have been previously published in the literature...
  27. doi [Time-resolved autofluorescence in retinal vascular occlusions]
    D Schweitzer
    Bereich Experimentelle Ophthalmologie, Augenklinik der FSU Jena, Bachstraße 18, Jena, Germany
    Ophthalmologe 107:1145-52. 2010
    ..In branch retinal artery occlusion, metabolic changes can be compared with normal tissue...
  28. doi [Haemoglobin oxygenation of retinal vessels in branch retinal artery occlusions over time and correlation with clinical outcome]
    S Gehlert
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Jena
    Klin Monbl Augenheilkd 227:976-80. 2010
    ..Purpose of these study was the evaluation of a new method for the measurement of haemoglobin oxygenation in retinal vessels. Patients with branch retinal artery occlusion have been measured before and after a rheological therapy...
  29. ncbi [Subjective sensations after intravitreal injection of bevacizumab]
    T Ach
    Klinik fur Augenheilkunde, Universitatsklinikum Jena
    Klin Monbl Augenheilkd 224:180-4. 2007
    ..The effects on subjective sensations are not always correlated with the objective changes...
  30. doi [Fusarium keratitis]
    R Augsten
    Klinik fur Augenheilkunde, Universitatsklinikum Jena, Bachstrasse 18, 07743, Jena, Deutschland
    Ophthalmologe 105:1043-5. 2008
    ..However, the infection progressed (endophthalmitis), and an enucleation was necessary. Despite modern drug therapy and surgical intervention, fungal keratitis can cause an enucleation...
  31. ncbi [Comparison of the corneal thickness as measured by Visante anterior segment OCT versus ultrasound technique]
    K Wildner
    Augenklinik, Klinikum der FSU Jena
    Klin Monbl Augenheilkd 224:832-6. 2007
    ..Thus, it is necessary to know the exact corneal thickness. A new non-contact technique for measuring the corneal thickness is available with the Visante anterior segment optical coherence tomography (OCT, Zeiss)...
  32. doi Age-related macular degeneration: Effects of a short-term intervention with an oleaginous kale extract--a pilot study
    Christin Arnold
    Institute of Nutrition, Friedrich Schiller University, Jena, Germany
    Nutrition 29:1412-7. 2013
    ..An increased dietary intake of xanthophylls is suggested to be inversely related to the risk of macular disease...
  33. ncbi Influence of flickering light on the retinal vessels in diabetic patients
    Aleksandra Mandecka
    Department of Internal Medicine III, Friedrich Schiller University, Bachstrasse 18, 07743, Jena, Germany
    Diabetes Care 30:3048-52. 2007
    ..The reduction of vasodilation is considered an endothelial dysfunction. We investigated the response of retinal vessels to flickering light in diabetic patients in different stages of diabetic retinopathy...
  34. ncbi Selenium and zinc in patients with acute and chronic uveitis
    J Dawczynski
    Department of Ophthalmology, University of Jena, Jena, Germany
    Biol Trace Elem Res 113:131-7. 2006
    ..Further studies should investigate possible positive effects of therapeutic selenium and zinc supplementation in patients with chronic, recurrent uveitis...
  35. ncbi Increased content of zinc and iron in human cataractous lenses
    J Dawczynski
    Department of Ophthalmology, University of Jena, Jena, Germany
    Biol Trace Elem Res 90:15-23. 2002
    ..These data suggest a possible influence of the lens zinc and iron content on the development of lens opacification. Especially advanced forms of cataract and dark brown colored lenses show significantly increased zinc and iron content...
  36. ncbi Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins
    Naila Ahmed
    Department of Biological Sciences, University of Essex, Central Campus, Wivenhoe Park, Colchester, Essex CO4 3SQ, United Kingdom
    Invest Ophthalmol Vis Sci 44:5287-92. 2003
    ....
  37. ncbi Developmental aspects of galectin-3 expression in the lens
    Ralf Dahm
    Max Planck Institute for Developmental Biology, Tubingen, Germany
    Histochem Cell Biol 119:219-26. 2003
    ..The spatiotemporal pattern of galectin-3 distribution during lens development favours a role of this lectin in adhesion processes and in the regulation of programmed organelle elimination during lens cell differentiation...