Research Topics
| Katja Schenke-LaylandSummaryAffiliation: Fraunhofer Institute of Toxicology and Experimental Medicine Country: Germany Publications
| Collaborators
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Detail Information
Publications
Tracheal tissue engineering: building on a strong foundationSvenja Hinderer
Department of Thoracic, Cardiac and Vascular Surgery, University Hospital and Inter University, Centre for Medical Technology Stuttgart Tübingen, Eberhard Karls University Tubingen, 72076 Tubingen, Germany
Expert Rev Med Devices 10:33-5. 2013....
Skin tissue engineering--in vivo and in vitro applicationsFlorian Groeber
Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, Stuttgart, Germany
Adv Drug Deliv Rev 63:352-66. 2011..We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening...
Recapitulation of the embryonic cardiovascular progenitor cell nicheKatja Schenke-Layland
Department of Cell and Tissue Engineering, Fraunhofer IGB, 70569 Stuttgart, Germany
Biomaterials 32:2748-56. 2011..Our study represents an innovative approach to bioengineer cardiac niches that can serve as unique 3D in vitro systems to facilitate CPC expansion and study CPC biology...
In vitro human tissue models--moving towards personalized regenerative medicineKatja Schenke-Layland
Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569 Stuttgart, Germany
Adv Drug Deliv Rev 63:195-6. 2011..These ex-vivo manufactured systems can also be used to study drug delivery dynamics...
Engineering of fibrillar decorin matrices for a tissue-engineered tracheaSvenja Hinderer
Department of Thoracic and Cardiovascular Surgery, University Hospital UKT and Inter University Centre for Medical Technology Stuttgart Tübingen IZST, Eberhard Karls University Tubingen, 72076 Tubingen, Germany
Biomaterials 33:5259-66. 2012..Our data suggest that these hybrid materials may be suitable as a substrate for tracheal tissue engineering...
Raman spectroscopy for the non-contact and non-destructive monitoring of collagen damage within tissuesMiriam Votteler
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Dept of Cell and Tissue Engineering, 70569 Stuttgart, Germany
J Biophotonics 5:47-56. 2012..In conclusion, our data demonstrate that Raman microscopy is a promising, non-destructive and non-contact tool to probe ECM state in situ...
Preclinical evaluation of ice-free cryopreserved arteries: structural integrity and hemocompatibilityAgnes J T Huber
Thoracic, Cardiac and Vascular Surgery, University Hospital, Tubingen, Germany
Cells Tissues Organs 196:262-70. 2012..The objective of this study was to determine whether or not ice-free cryopreservation causes tissue changes that might preclude clinical use...
Electrospun poly(D/L-lactide-co-L-lactide) hybrid matrix: a novel scaffold material for soft tissue engineeringPetra J Kluger
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569, Stuttgart, Germany
J Mater Sci Mater Med 21:2665-71. 2010..Our data demonstrate the applicability of electrospun poly(D/L-lactide-co-L-lactide) scaffolds to serve as substrates for regenerative medicine applications with special focus on skin tissue engineering...
Skin tissue engineering-in vivo and in vitro applicationsFlorian Groeber
Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569 Stuttgart, Germany Institute for Interfacial Engineering, Nobelstrasse 12, 70569 Stuttgart, Germany
Clin Plast Surg 39:33-58. 2012..We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening...
The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestineJacqueline Pusch
Fraunhofer Institute for Interfacial Engineering and Biotechnology, Department of Cell and Tissue Engineering, Stuttgart, Germany
Biomaterials 32:7469-78. 2011..We conclude that the integration of physiological parameters is crucial for the establishment of a reliable 3D intestinal in vitro model, which enables the simulation of drug transport over the gut-blood-barrier in a simplified way...
Stem cell microenvironments--unveiling the secret of how stem cell fate is definedMiriam Votteler
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Department of Cell and Tissue Engineering, Nobelstrasse 12, 70569 Stuttgart, Germany
Macromol Biosci 10:1302-15. 2010..In this article, we review work highlighting the growing complexity of stem cell-ECM interactions and their impact on the fields of biomaterials research and regenerative medicine...
Non-invasive identification of proteoglycans and chondrocyte differentiation state by Raman microspectroscopyMarieke Pudlas
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Dept of Cell and Tissue Engineering, Nobelstr 12, 70569 Stuttgart, Germany
J Biophotonics 6:205-11. 2013..Our results are the first to demonstrate the applicability of Raman microspectroscopy as an analytical and potential diagnostic tool for non-invasive cell and tissue state monitoring of cartilage in biomedical research...
RNA isolation from fetal and adult human tissues for transcriptional profilingMiriam Votteler
Department of Thoracic and Cardiovascular Surgery, Inter University Centre for Medical Technology Stuttgart Tübingen IZST at the University Hospital Tübingen UKT, Eberhard Karls University, Tubingen, Germany
Biotechnol J 8:338-44. 2013..In this study, we present an improved standard processing procedure for tissue sample processing and analysis of rare human cardiovascular tissues...
Oligonucleotide and Parylene Surface Coating of Polystyrene and ePTFE for Improved Endothelial Cell Attachment and HemocompatibilityMartina Schleicher
Department of Thoracic, Cardiac and Vascular Surgery, University Hospital, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
Int J Biomater 2012:397813. 2012..These properties suggest the suitability of immobilization of DNA-oligonucleotides for biofunctionalization of blood vessel substitutes for improved in vivo endothelialization...
Raman spectroscopy: a noninvasive analysis tool for the discrimination of human skin cellsMarieke Pudlas
Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany
Tissue Eng Part C Methods 17:1027-40. 2011..We conclude therefore that Raman spectroscopy is a suitable tool for the noninvasive in situ quality control of cells used in skin tissue engineering applications...
