Katja Schenke-Layland

Summary

Affiliation: Fraunhofer Institute of Toxicology and Experimental Medicine
Country: Germany

Publications

  1. pmc Raman spectroscopy in biomedicine - non-invasive in vitro analysis of cells and extracellular matrix components in tissues
    Eva Brauchle
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany
    Biotechnol J 8:288-97. 2013
  2. pmc Electrospun poly(D/L-lactide-co-L-lactide) hybrid matrix: a novel scaffold material for soft tissue engineering
    Petra J Kluger
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569, Stuttgart, Germany
    J Mater Sci Mater Med 21:2665-71. 2010
  3. doi request reprint Tracheal tissue engineering: building on a strong foundation
    Svenja Hinderer
    Department of Thoracic, Cardiac and Vascular Surgery, University Hospital and Inter University, Centre for Medical Technology Stuttgart Tübingen, Eberhard Karls University Tubingen, 72076 Tubingen, Germany
    Expert Rev Med Devices 10:33-5. 2013
  4. doi request reprint Skin tissue engineering--in vivo and in vitro applications
    Florian Groeber
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, Stuttgart, Germany
    Adv Drug Deliv Rev 63:352-66. 2011
  5. pmc Recapitulation of the embryonic cardiovascular progenitor cell niche
    Katja Schenke-Layland
    Department of Cell and Tissue Engineering, Fraunhofer IGB, 70569 Stuttgart, Germany
    Biomaterials 32:2748-56. 2011
  6. doi request reprint In vitro human tissue models--moving towards personalized regenerative medicine
    Katja Schenke-Layland
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569 Stuttgart, Germany
    Adv Drug Deliv Rev 63:195-6. 2011
  7. doi request reprint Engineering of fibrillar decorin matrices for a tissue-engineered trachea
    Svenja Hinderer
    Department of Thoracic and Cardiovascular Surgery, University Hospital UKT and Inter University Centre for Medical Technology Stuttgart Tübingen IZST, Eberhard Karls University Tubingen, 72076 Tubingen, Germany
    Biomaterials 33:5259-66. 2012
  8. doi request reprint Raman spectroscopy for the non-contact and non-destructive monitoring of collagen damage within tissues
    Miriam Votteler
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Dept of Cell and Tissue Engineering, 70569 Stuttgart, Germany
    J Biophotonics 5:47-56. 2012
  9. doi request reprint Stem cell microenvironments--unveiling the secret of how stem cell fate is defined
    Miriam Votteler
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Department of Cell and Tissue Engineering, Nobelstrasse 12, 70569 Stuttgart, Germany
    Macromol Biosci 10:1302-15. 2010
  10. doi request reprint Non-invasive identification of proteoglycans and chondrocyte differentiation state by Raman microspectroscopy
    Marieke Pudlas
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Dept of Cell and Tissue Engineering, Nobelstr 12, 70569 Stuttgart, Germany
    J Biophotonics 6:205-11. 2013

Collaborators

  • Marieke Pudlas
  • Florian Groeber
  • Johannes A Eble
  • Dietmar W Hutmacher
  • Ulrich A Stock
  • Thorsten Walles
  • Matthias Schnabelrauch
  • Robert M Nerem
  • Miriam Votteler
  • Svenja Hinderer
  • Eva Brauchle
  • Heike Walles
  • Petra J Kluger
  • Martina Seifert
  • Agnes J T Huber
  • Martina Schleicher
  • Anke Hoppensack
  • Marianne K Schesny
  • Sibylle Thude
  • Kelvin G M Brockbank
  • Olaf Fritze
  • Hans Peter Wendel
  • Martina Hampel
  • Jacqueline Pusch
  • Johanna Schanz
  • Nian Shen
  • Jan Seifert
  • Christian C Kazanecki
  • Meinrad P Gawaz
  • Michael Monaghan
  • Anna Gosiewska
  • Sebastian Vogel
  • Johannes Rheinlaender
  • Désirée Freund
  • Tilman E Schäffer
  • Sara Y Brucker
  • Andrea H Bindermann
  • David Colter
  • Alexander Horke
  • Hannah Johannsen
  • Shannon L Layland
  • Samantha Nolan
  • Georgia Lill
  • Marianne Schesny
  • Iris Riemann
  • Jan Hansmann
  • Bentsian Elkin
  • Bettina Ibold
  • Daniel A Carvajal Berrio
  • Michaela Muller
  • Christine Schille
  • Simone Liebscher
  • Alexandra Bayrak
  • Stella Göhler
  • Jasmin Engl
  • Ralf Wyrwa
  • Jürgen Weisser
  • Julia Maierle
  • Claudia Rode

Detail Information

Publications22

  1. pmc Raman spectroscopy in biomedicine - non-invasive in vitro analysis of cells and extracellular matrix components in tissues
    Eva Brauchle
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany
    Biotechnol J 8:288-97. 2013
    ....
  2. pmc Electrospun poly(D/L-lactide-co-L-lactide) hybrid matrix: a novel scaffold material for soft tissue engineering
    Petra J Kluger
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569, Stuttgart, Germany
    J Mater Sci Mater Med 21:2665-71. 2010
    ..Our data demonstrate the applicability of electrospun poly(D/L-lactide-co-L-lactide) scaffolds to serve as substrates for regenerative medicine applications with special focus on skin tissue engineering...
  3. doi request reprint Tracheal tissue engineering: building on a strong foundation
    Svenja Hinderer
    Department of Thoracic, Cardiac and Vascular Surgery, University Hospital and Inter University, Centre for Medical Technology Stuttgart Tübingen, Eberhard Karls University Tubingen, 72076 Tubingen, Germany
    Expert Rev Med Devices 10:33-5. 2013
    ....
  4. doi request reprint Skin tissue engineering--in vivo and in vitro applications
    Florian Groeber
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, Stuttgart, Germany
    Adv Drug Deliv Rev 63:352-66. 2011
    ..We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening...
  5. pmc Recapitulation of the embryonic cardiovascular progenitor cell niche
    Katja Schenke-Layland
    Department of Cell and Tissue Engineering, Fraunhofer IGB, 70569 Stuttgart, Germany
    Biomaterials 32:2748-56. 2011
    ..Our study represents an innovative approach to bioengineer cardiac niches that can serve as unique 3D in vitro systems to facilitate CPC expansion and study CPC biology...
  6. doi request reprint In vitro human tissue models--moving towards personalized regenerative medicine
    Katja Schenke-Layland
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569 Stuttgart, Germany
    Adv Drug Deliv Rev 63:195-6. 2011
    ..These ex-vivo manufactured systems can also be used to study drug delivery dynamics...
  7. doi request reprint Engineering of fibrillar decorin matrices for a tissue-engineered trachea
    Svenja Hinderer
    Department of Thoracic and Cardiovascular Surgery, University Hospital UKT and Inter University Centre for Medical Technology Stuttgart Tübingen IZST, Eberhard Karls University Tubingen, 72076 Tubingen, Germany
    Biomaterials 33:5259-66. 2012
    ..Our data suggest that these hybrid materials may be suitable as a substrate for tracheal tissue engineering...
  8. doi request reprint Raman spectroscopy for the non-contact and non-destructive monitoring of collagen damage within tissues
    Miriam Votteler
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Dept of Cell and Tissue Engineering, 70569 Stuttgart, Germany
    J Biophotonics 5:47-56. 2012
    ..In conclusion, our data demonstrate that Raman microscopy is a promising, non-destructive and non-contact tool to probe ECM state in situ...
  9. doi request reprint Stem cell microenvironments--unveiling the secret of how stem cell fate is defined
    Miriam Votteler
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Department of Cell and Tissue Engineering, Nobelstrasse 12, 70569 Stuttgart, Germany
    Macromol Biosci 10:1302-15. 2010
    ..In this article, we review work highlighting the growing complexity of stem cell-ECM interactions and their impact on the fields of biomaterials research and regenerative medicine...
  10. doi request reprint Non-invasive identification of proteoglycans and chondrocyte differentiation state by Raman microspectroscopy
    Marieke Pudlas
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Dept of Cell and Tissue Engineering, Nobelstr 12, 70569 Stuttgart, Germany
    J Biophotonics 6:205-11. 2013
    ..Our results are the first to demonstrate the applicability of Raman microspectroscopy as an analytical and potential diagnostic tool for non-invasive cell and tissue state monitoring of cartilage in biomedical research...
  11. doi request reprint Design and analysis of a squamous cell carcinoma in vitro model system
    Eva Brauchle
    Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Department of Cell and Tissue Engineering, Stuttgart, Germany
    Biomaterials 34:7401-7. 2013
    ....
  12. ncbi request reprint Preclinical evaluation of ice-free cryopreserved arteries: structural integrity and hemocompatibility
    Agnes J T Huber
    Thoracic, Cardiac and Vascular Surgery, University Hospital, Tubingen, Germany
    Cells Tissues Organs 196:262-70. 2012
    ..The objective of this study was to determine whether or not ice-free cryopreservation causes tissue changes that might preclude clinical use...
  13. ncbi request reprint Skin tissue engineering-in vivo and in vitro applications
    Florian Groeber
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobelstrasse 12, 70569 Stuttgart, Germany Institute for Interfacial Engineering, Nobelstrasse 12, 70569 Stuttgart, Germany
    Clin Plast Surg 39:33-58. 2012
    ..We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening...
  14. ncbi request reprint The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine
    Jacqueline Pusch
    Fraunhofer Institute for Interfacial Engineering and Biotechnology, Department of Cell and Tissue Engineering, Stuttgart, Germany
    Biomaterials 32:7469-78. 2011
    ..We conclude that the integration of physiological parameters is crucial for the establishment of a reliable 3D intestinal in vitro model, which enables the simulation of drug transport over the gut-blood-barrier in a simplified way...
  15. pmc Cell death stages in single apoptotic and necrotic cells monitored by Raman microspectroscopy
    Eva Brauchle
    1 Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Department of Cell and Tissue Engineering, Nobelstr 12, 70569 Stuttgart, Germany 2 University of Stuttgart, Institute of Interfacial Process Engineering and Plasma Technology IGVP, Nobelstr 12, 70569 Stuttgart, Germany
    Sci Rep 4:4698. 2014
    ..To conclude, Raman spectroscopy allows a non-invasive, continuous monitoring of cell death, which may help shedding new light on complex pathophysiological or drug-induced cell death processes. ..
  16. doi request reprint Engineering of a bio-functionalized hybrid off-the-shelf heart valve
    Svenja Hinderer
    University Women s Hospital, Eberhard Karls University Tubingen, 72076 Tubingen, Germany Dept of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, 70569 Stuttgart, Germany Institute for Interfacial Process Engineering and Plasma Technology IGVP, University of Stuttgart, 70569 Stuttgart, Germany
    Biomaterials 35:2130-9. 2014
    ..As a proof of principle, these proteins were introduced to the scaffold, demonstrating the ability to bio-functionalize the hybrid valve based on natures' blueprint. ..
  17. ncbi request reprint Preserved bioactivity and tunable release of a SDF1-GPVI bi-specific protein using photo-crosslinked PEGda hydrogels
    Marianne K Schesny
    University Women s Hospital, Eberhard Karls University Tubingen, 72076 Tubingen, Germany Dept of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, 70569 Stuttgart, Germany
    Biomaterials 35:7180-7. 2014
    ....
  18. pmc A human in vitro model that mimics the renal proximal tubule
    Anke Hoppensack
    1 Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany
    Tissue Eng Part C Methods 20:599-609. 2014
    ..Basement membrane and microvilli formation demonstrated a strong polarization. We conclude that the combination of hKDCs and SIS is a suitable cell-scaffold composite to mimic the human PT in vitro. ..
  19. doi request reprint RNA isolation from fetal and adult human tissues for transcriptional profiling
    Miriam Votteler
    Department of Thoracic and Cardiovascular Surgery, Inter University Centre for Medical Technology Stuttgart Tübingen IZST at the University Hospital Tübingen UKT, Eberhard Karls University, Tubingen, Germany
    Biotechnol J 8:338-44. 2013
    ..In this study, we present an improved standard processing procedure for tissue sample processing and analysis of rare human cardiovascular tissues...
  20. pmc Oligonucleotide and Parylene Surface Coating of Polystyrene and ePTFE for Improved Endothelial Cell Attachment and Hemocompatibility
    Martina Schleicher
    Department of Thoracic, Cardiac and Vascular Surgery, University Hospital, Hoppe Seyler Strasse 3, 72076 Tuebingen, Germany
    Int J Biomater 2012:397813. 2012
    ..These properties suggest the suitability of immobilization of DNA-oligonucleotides for biofunctionalization of blood vessel substitutes for improved in vivo endothelialization...
  21. doi request reprint Raman spectroscopy: a noninvasive analysis tool for the discrimination of human skin cells
    Marieke Pudlas
    Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany
    Tissue Eng Part C Methods 17:1027-40. 2011
    ..We conclude therefore that Raman spectroscopy is a suitable tool for the noninvasive in situ quality control of cells used in skin tissue engineering applications...