Affiliation: Fraunhofer Institute of Toxicology and Experimental Medicine
Requardt H, Braun A, Steinberg P, Hampel S, Hansen T. Surface defects reduce carbon nanotube toxicity in vitro. Toxicol In Vitro. 2019;: pubmed publisher
..Both MWCNTs induced a significant cytotoxicity, whereby the heat treatment, leading to a decrease in surface defects, further increased the indicated adverse effects. ..
Schaumann F, FrÃ¶mke C, Dijkstra D, Alessandrini F, Windt H, Karg E, et al
. Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: results of a double-blinded randomized cross-over clinical pilot study. Part Fibre Toxicol. 2014;11:39 pubmed publisher
..This should be reconfirmed in further studies with an appropriate study design and sufficient number of subjects. ..
Koch A, Saran S, Tran D, Klebba FÃ¤rber S, Thiesler H, Sewald K, et al
. Murine precision-cut liver slices (PCLS): a new tool for studying tumor microenvironments and cell signaling ex vivo. Cell Commun Signal. 2014;12:73 pubmed publisher
..This method may also prove useful for identification of genes in liver-resident cells that support cancer invasion by using PCLS from transgenic liver. ..
Booth J, Duggan E, Patel V, Langer M, Wu W, Braun A, et al
. Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models. Microbes Infect. 2016;18:615-626 pubmed publisher
..Our results support a model of spore escape from the alveolus that involves spore clustering with transient passage through intact AEC. However, subsequent transport of spores by APC from the lung to the lymph nodes may occur. ..