Christiane Franzius

Summary

Country: Germany

Publications

  1. ncbi High-activity samarium-153-EDTMP therapy in unresectable osteosarcoma
    C Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    Nuklearmedizin 38:337-40. 1999
  2. ncbi [Procedure guideline for radioiodine therapy and 131iodine whole-body scintigraphy in paediatric patients with differentiated thyroid cancer]
    C Franzius
    Kliniken und Polikliniken für Nuklearmedizin, Universitätsklinika Münster, Albert Schweitzer Str 33, 48129 Munster
    Nuklearmedizin 46:224-31. 2007
  3. ncbi Whole-body PET/CT with 11C-meta-hydroxyephedrine in tumors of the sympathetic nervous system: feasibility study and comparison with 123I-MIBG SPECT/CT
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    J Nucl Med 47:1635-42. 2006
  4. ncbi Successful high-resolution animal positron emission tomography of human Ewing tumours and their metastases in a murine xenograft model
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital Munster, Munster, Germany
    Eur J Nucl Med Mol Imaging 33:1432-41. 2006
  5. ncbi Is PET/CT necessary in paediatric oncology? For
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Strasse 33, 48149, Munster, Germany
    Eur J Nucl Med Mol Imaging 33:960-5. 2006
  6. ncbi FDG PET: advantages for staging the mediastinum?
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Strasse 33, D 48149 Munster, Germany
    Lung Cancer 45:S69-74. 2004
  7. ncbi Assessment of therapy response by FDG PET in pediatric patients
    C Franzius
    Department of Nuclear Medicine, Munster University, Munster, Germany
    Q J Nucl Med 47:41-5. 2003
  8. ncbi Prognostic significance of (18)F-FDG and (99m)Tc-methylene diphosphonate uptake in primary osteosarcoma
    Christiane Franzius
    Department of Nuclear Medicine, Munster University Hospital, Germany
    J Nucl Med 43:1012-7. 2002
  9. ncbi 3-[123I]Iodo-L-alpha-methyl tyrosine transport into human fibroblasts and comparison with Ewing's sarcoma cells
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital, Muenster, Germany
    Nucl Med Biol 29:483-90. 2002
  10. ncbi FDG-PET for detection of recurrences from malignant primary bone tumors: comparison with conventional imaging
    C Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    Ann Oncol 13:157-60. 2002

Detail Information

Publications35

  1. ncbi High-activity samarium-153-EDTMP therapy in unresectable osteosarcoma
    C Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    Nuklearmedizin 38:337-40. 1999
    ....
  2. ncbi [Procedure guideline for radioiodine therapy and 131iodine whole-body scintigraphy in paediatric patients with differentiated thyroid cancer]
    C Franzius
    Kliniken und Polikliniken für Nuklearmedizin, Universitätsklinika Münster, Albert Schweitzer Str 33, 48129 Munster
    Nuklearmedizin 46:224-31. 2007
    ..Reference values of fT3 are higher in children than in adults. Evidence is insufficient to describe in which constellation the TSH may be kept within the low normal level. Therefore, TSH suppression is generally recommended...
  3. ncbi Whole-body PET/CT with 11C-meta-hydroxyephedrine in tumors of the sympathetic nervous system: feasibility study and comparison with 123I-MIBG SPECT/CT
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    J Nucl Med 47:1635-42. 2006
    ....
  4. ncbi Successful high-resolution animal positron emission tomography of human Ewing tumours and their metastases in a murine xenograft model
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital Munster, Munster, Germany
    Eur J Nucl Med Mol Imaging 33:1432-41. 2006
    ..The aim of this study was to evaluate the feasibility of diagnostic molecular imaging by small animal PET in this mouse model...
  5. ncbi Is PET/CT necessary in paediatric oncology? For
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Strasse 33, 48149, Munster, Germany
    Eur J Nucl Med Mol Imaging 33:960-5. 2006
  6. ncbi FDG PET: advantages for staging the mediastinum?
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Strasse 33, D 48149 Munster, Germany
    Lung Cancer 45:S69-74. 2004
    ..Data comparing FDG PET with other functional imaging modalities or endoscopic ultrasound are limited. The necessity of a histological confirmation of PET results is still under discussion...
  7. ncbi Assessment of therapy response by FDG PET in pediatric patients
    C Franzius
    Department of Nuclear Medicine, Munster University, Munster, Germany
    Q J Nucl Med 47:41-5. 2003
    ..There is a need for large, systematic studies evaluating FDG PET in therapy monitoring, but also in grading, staging, and in the diagnosis of recurrences in pediatric malignancies...
  8. ncbi Prognostic significance of (18)F-FDG and (99m)Tc-methylene diphosphonate uptake in primary osteosarcoma
    Christiane Franzius
    Department of Nuclear Medicine, Munster University Hospital, Germany
    J Nucl Med 43:1012-7. 2002
    ....
  9. ncbi 3-[123I]Iodo-L-alpha-methyl tyrosine transport into human fibroblasts and comparison with Ewing's sarcoma cells
    Christiane Franzius
    Department of Nuclear Medicine, University Hospital, Muenster, Germany
    Nucl Med Biol 29:483-90. 2002
    ..These results were compared with those determined in two malignantly transformed extracranial cell lines, the human Ewing's sarcoma cell lines VH-64 and CADO-ES-1...
  10. ncbi FDG-PET for detection of recurrences from malignant primary bone tumors: comparison with conventional imaging
    C Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    Ann Oncol 13:157-60. 2002
    ....
  11. ncbi Evaluation of chemotherapy response in primary bone tumors with F-18 FDG positron emission tomography compared with histologically assessed tumor necrosis
    C Franzius
    Department of Nuclear Medicine, University Hospital, Westfalische Wilhelms Universitat, Munster, Germany
    Clin Nucl Med 25:874-81. 2000
    ....
  12. ncbi High-activity samarium-153-EDTMP therapy followed by autologous peripheral blood stem cell support in unresectable osteosarcoma
    C Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    Nuklearmedizin 40:215-20. 2001
    ..Despite highly efficacious chemotherapy, patients with osteosarcomas still have a poor prognosis if adequate surgical control cannot be obtained. These patients may benefit from therapy with radiolabeled phosphonates...
  13. ncbi [Clinical value of positron emission tomography (PET) in the diagnosis of bone and soft tissue tumors. 3rd Interdisciplinary Consensus Conference "PET in Oncology": results of the Bone and Soft Tissue Study Group]
    C Franzius
    Klinik und Poliklinik fur Nuklearmedizin, Westfalische Wilhelms Universitat Munster
    Chirurg 72:1071-7. 2001
    ..In the framework of the 3rd Consensus Conference "PET in Oncology" the bone and soft-tissue tumors study group evaluated the present position of PET for these tumor entities on the basis of international publications...
  14. ncbi Characterization of 3-[123I]iodo-L-alpha-methyl tyrosine ([123I]IMT) transport into human Ewing's sarcoma cells in vitro
    C Franzius
    Department of Nuclear Medicine, Westfalische Wilhelms Universitat, Munster, Albert Schweitzer Str 33, 48149, Munster, Germany
    Nucl Med Biol 28:123-8. 2001
    ..7+/-3.9 microM) and maximum transport velocitiy amounted to V(max)=20.7+/-0.6 nmol x mg protein(-1) x 10 min(-1). Inhibition experiments revealed the predominance of [(123)I]IMT uptake via sodium-independent system L...
  15. ncbi FDG-PET for detection of pulmonary metastases from malignant primary bone tumors: comparison with spiral CT
    C Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    Ann Oncol 12:479-86. 2001
    ..The purpose was the comparison of positron emission tomography using F-18-fluorodeoxy-glucose (FDG-PET) and spiral thoracic CT to detect pulmonary metastases from malignant primary osseous tumors...
  16. doi Diagnostic impact of 18F-FDG PET-CT evaluating solid pancreatic lesions versus endosonography, endoscopic retrograde cholangio-pancreatography with intraductal ultrasonography and abdominal ultrasound
    Verena Schick
    Department of Medicine B, Muenster University Hospital, Albert Schweitzer Strasse 33, 48149 Muenster, Germany
    Eur J Nucl Med Mol Imaging 35:1775-85. 2008
    ....
  17. ncbi Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography
    Matthias Stelljes
    Department of Medicine Hematology and Oncology, University of Muenster, Albert Schweitzer Strasse 33, Muenster, Germany
    Blood 111:2909-18. 2008
    ..Novel targeted tracers for PET may provide new insights into the pathophysiology of GVHD and bear the potential to further improve GVHD diagnosis...
  18. ncbi Significant benefit of multimodal imaging: PET/CT compared with PET alone in staging and follow-up of patients with Ewing tumors
    Hans U Gerth
    Department of Nuclear Medicine, University Hospital Munster, Munster, Germany
    J Nucl Med 48:1932-9. 2007
    ..Hybrid PET/CT was compared with PET alone in the staging and restaging of patients with Ewing tumor to assess the benefit of the combined imaging technique...
  19. ncbi Iodine excretion during stimulation with rhTSH in differentiated thyroid carcinoma
    M Loffler
    Department of Nuclear Medicine, University of Munster, Albert Schweitzer Strasse 33, 48129 Munster, Germany
    Nuklearmedizin 42:240-3. 2003
    ..The aim of this study was to assess the iodine excretion depending on different ways of stimulation...
  20. ncbi High diagnostic value of 18F-FDG-PET in pediatric patients with chronic inflammatory bowel disease
    M Loffler
    Department of Nuclear Medicine, University Hospital Muenster, Albert Schweitzer Strasse 33, 48129 Muenster, Germany
    Ann N Y Acad Sci 1072:379-85. 2006
    ..Depicting inflammation in the whole bowel, while being not traumatic, it is attractive for use especially in children. FDG-PET is especially reliable for the small bowel and can inform application of topical therapy...
  21. ncbi Kinetic parameters of 3-[(123)I]iodo-L-alpha-methyl tyrosine ([(123)I]IMT) transport in human GOS3 glioma cells
    B Riemann
    Department of Nuclear MedicineWestfälische Wilhelms Universität, Munster, Germany
    Nucl Med Biol 28:293-7. 2001
    ..1 +/- 1.5 microM). The maximum transport velocity (V(max)) amounted to 34.8 +/- 1.9 nmol/mg protein/10 min. Competitive inhibition experiments revealed that [(123)I]IMT transport is mediated principally by the sodium-independent system L...
  22. ncbi [Role of FDG-PET in oncological surgery]
    G Schurmann
    Klinik und Poliklinik für Allgemeine Chirurgie, Westfalische Wilhelms Universitat Munster
    Chirurg 72:528-36. 2001
    ..This short review describes the biological basis of [18F]FDG-PET and gives a critical discussion of its role in oncological surgery...
  23. ncbi Whole-body imaging of oncologic patients using 16-channel PET-CT. Evaluation of an i.v. contrast enhanced MDCT protocol
    K U Juergens
    Department of Clinical Radiology, University of Muenster, Albert Schweitzer Strasse 33, 48149 Muenster, Germany
    Nuklearmedizin 47:30-6. 2008
    ....
  24. ncbi Tumor staging using whole-body high-resolution 16-channel PET-CT: does additional low-dose chest CT in inspiration improve the detection of solitary pulmonary nodules?
    K U Juergens
    Department of Clinical Radiology, University of Muenster, Albert Schweitzer Strabe 33, 48149 Muenster, Germany
    Eur Radiol 16:1131-7. 2006
    ..001). Additional I-LDCT of the chest significantly improves the detection of SPN at whole-body F-18-FDG-PET-CT and thus is recommended as part of the standard protocol for oncological patients...
  25. ncbi Staging in childhood lymphoma: differences between FDG-PET and CT
    S Hermann
    Department of Nuclear Medicine, University Hospital Munster, Albert Schweitzer Str 33, 48149 Munster, Germany
    Nuklearmedizin 44:1-7. 2005
    ..However, there are only few data regarding childhood lymphoma. The purpose of this retrospective study was to compare the staging of childhood lymphoma using FDG-PET and the established computed tomography (CT)...
  26. doi PET surveillance of patients with Ewing sarcomas of the trunk: Must the lower legs be included?
    A Vrachimis
    Klinik und Poliklinik fur Nuklearmedizin, Universitatsklinikum Munster, Albert Schweitzer Str 33, 48149 Munster, Germany
    Nuklearmedizin 49:183-6. 2010
    ..Almost all of the patients had undergone a combined chemotherapy with surgery or/and radiotherapy. 156 follow-up PET scans of the legs of these patients were evaluated retrospectively...
  27. ncbi Mucinous cystadenocarcinoma--an extremely rare tumor in a young patient
    O Sezer
    Department of Thoracic and Cardiovascular Surgery, University Hospital of Munster, Munster, Germany
    Thorac Cardiovasc Surg 54:216-7. 2006
    ..This case is the youngest patient reported so far with a malignant pulmonary mucinous cystadenocarcinoma and highlights the importance of close follow-up of indeterminate pulmonary nodules in patients with unremarkable history...
  28. ncbi Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET
    H E Daldrup-Link
    Department of Clinical Radiology, , , Germany
    AJR Am J Roentgenol 177:229-36. 2001
    ..Most false-positive lesions were diagnosed using FDG PET. CONCLUSION: Whole-body MR imaging has a higher sensitivity than skeletal scintigraphy for the detection of bone marrow metastases but a lower sensitivity than FDG PET...
  29. ncbi Metastatic neuroblastoma demonstrated by whole-body PET-CT using 11C-HED
    C Franzius
    Department of Nuclear Medicine, University Hospital, Munster, Germany
    Nuklearmedizin 44:N4-5. 2005
  30. ncbi Clinical value of parathyroid scintigraphy with technetium-99m methoxyisobutylisonitrile: discrepancies in clinical data and a systematic metaanalysis of the literature
    Martin Gotthardt
    Department of Nuclear Medicine, Philipps University of Marburg, Baldingerstrasse, 35043 Marburg, Germany
    World J Surg 28:100-7. 2004
    ..We believe that a well-designed and properly conducted prospective study is necessary to evaluate the reasons for the differences observed...
  31. ncbi Follow-up of perfusion defects in pulmonary perfusion scanning after pulmonary embolism: are we too careless?
    M Gotthardt
    Department of Nuclear Medicine, Philipps University of Marburg, Germany
    Nucl Med Commun 23:447-52. 2002
    ..In many cases, there was no further follow-up even if reperfusion of the defects was lacking in early follow-up...
  32. doi The role of positron emission tomography in the evaluation of residual masses after chemotherapy for advanced stage seminoma
    Stefan Hinz
    Department of Urology, Charite Campus Benjamin Franklin, Universitaetsmedizin Berlin, Berlin, Germany
    J Urol 179:936-40; discussion 940. 2008
    ..We analyzed the accuracy of preoperative positron emission tomography for predicting viable tumor residuals in patients with seminoma...
  33. ncbi Skip metastases in osteosarcoma: experience of the Cooperative Osteosarcoma Study Group
    Leo Kager
    St Anna Children s Hospital, Vienna, Austria
    J Clin Oncol 24:1535-41. 2006
    ..This study was conducted to further investigate the prognostic implication of skip metastases in osteosarcoma...
  34. ncbi PET/CT with diagnostic CT in the evaluation of childhood sarcoma
    Christiane Franzius
    AJR Am J Roentgenol 186:581; author reply 581-2. 2006
  35. ncbi [Pulmonary aspergillosis as initial manifestation of septic granulomatosis (chronic granulomatous disease, CGD) in a premature monozygotic female twin and FDG-PET diagnosis of spread of the disease]
    Iris Theobald
    Institut für Klinische Radiologie des UKM, Albert Schweitzer Str 33, 48129 Munster
    Radiologe 42:42-5. 2002
    ..To demonstrate and to discuss the complex diagnosis and the diagnostic value of FDG-PET in monitoring the spread and activity of the disease...