W M Franz

Summary

Country: Germany

Publications

  1. ncbi Analysis of tissue-specific gene delivery by recombinant adenoviruses containing cardiac-specific promoters
    W M Franz
    Medizinische Klinik II, Medizinische Universitat zu Lubeck, Germany
    Cardiovasc Res 35:560-6. 1997
  2. ncbi The 2.3 kb smooth muscle myosin heavy chain promoter directs gene expression into the vascular system of transgenic mice and rabbits
    W M Franz
    Medizinische Klinik II, University of Lubeck, Germany
    Cardiovasc Res 43:1040-8. 1999
  3. ncbi Association of nonsense mutation of dystrophin gene with disruption of sarcoglycan complex in X-linked dilated cardiomyopathy
    W M Franz
    Medizinische Klinik II, University of Lubeck, Germany
    Lancet 355:1781-5. 2000
  4. ncbi Transgenic animal models: new avenues in cardiovascular physiology
    W M Franz
    Medizinische Klinik II, Universitat Lubeck, Germany
    J Mol Med (Berl) 75:115-29. 1997
  5. ncbi Novel splice donor site mutation in the cardiac myosin-binding protein-C gene in familial hypertrophic cardiomyopathy. Characterization Of cardiac transcript and protein
    W Rottbauer
    Medizinische Klinik III, Universitat Heidelberg, D 69115 Heidelberg, Germany
    J Clin Invest 100:475-82. 1997
  6. ncbi Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias
    N Frey
    Department of Internal Medicine II and Department of Pathology, Medical University of Luebeck, Germany
    Cardiovasc Res 47:254-64. 2000
  7. ncbi Contrasting obesity phenotypes uncovered by partial leptin receptor gene deletion in transgenic mice
    U Reichart
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Vienna, A 1210, Austria
    Biochem Biophys Res Commun 269:502-7. 2000
  8. ncbi [Embryonic stem cells. Future perspectives]
    M Groebner
    Medizinische Klinik und Poliklinik I, ,
    Internist (Berl) 47:502, 504-8. 2006

Collaborators

  • R D Cohn
  • A F Moorman
  • M Muller
  • J Zehelein
  • M Gautel
  • M Groebner
  • N Frey
  • U Reichart
  • H A Katus
  • R David
  • W Rottbauer
  • M Degenhardt
  • E Wolf
  • K Gloeckner
  • B Aigner
  • G Brem
  • O Muller
  • O J Müller
  • A Höflich
  • I Renner-Müller
  • H Merz
  • B Vollrath
  • S Labeit
  • C Fischer
  • W Kubler
  • R Dietz
  • G Mall

Detail Information

Publications8

  1. ncbi Analysis of tissue-specific gene delivery by recombinant adenoviruses containing cardiac-specific promoters
    W M Franz
    Medizinische Klinik II, Medizinische Universitat zu Lubeck, Germany
    Cardiovasc Res 35:560-6. 1997
    ..To approach heart muscle diseases by gene transfer, an adenoviral vector system was intended to be established suitable for gene expression in ventricular and/or atrial myocardium...
  2. ncbi The 2.3 kb smooth muscle myosin heavy chain promoter directs gene expression into the vascular system of transgenic mice and rabbits
    W M Franz
    Medizinische Klinik II, University of Lubeck, Germany
    Cardiovasc Res 43:1040-8. 1999
    ..Since the 2.3 kb rabbit Smooth Muscle Myosin Heavy Chain (SMHC) promoter was shown to be transcriptionally active in primary vascular but not visceral or other non-SMC in vitro, this fragment was chosen for in vivo analysis...
  3. ncbi Association of nonsense mutation of dystrophin gene with disruption of sarcoglycan complex in X-linked dilated cardiomyopathy
    W M Franz
    Medizinische Klinik II, University of Lubeck, Germany
    Lancet 355:1781-5. 2000
    ..We have now attempted to eludicate the genetic mechanism involved in this disease, as well as the role of dystrophin-associated glycoproteins...
  4. ncbi Transgenic animal models: new avenues in cardiovascular physiology
    W M Franz
    Medizinische Klinik II, Universitat Lubeck, Germany
    J Mol Med (Berl) 75:115-29. 1997
    ..These recent advances in transgenic technology are expected to have a considerable impact on cardiovascular research in the near future...
  5. ncbi Novel splice donor site mutation in the cardiac myosin-binding protein-C gene in familial hypertrophic cardiomyopathy. Characterization Of cardiac transcript and protein
    W Rottbauer
    Medizinische Klinik III, Universitat Heidelberg, D 69115 Heidelberg, Germany
    J Clin Invest 100:475-82. 1997
    ....
  6. ncbi Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias
    N Frey
    Department of Internal Medicine II and Department of Pathology, Medical University of Luebeck, Germany
    Cardiovasc Res 47:254-64. 2000
    ..To investigate the causal relationship of cTnT mutations and this particular phenotype, we sought to establish a transgenic rat model for the disease...
  7. ncbi Contrasting obesity phenotypes uncovered by partial leptin receptor gene deletion in transgenic mice
    U Reichart
    Institut fur Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Veterinarplatz 1, Vienna, A 1210, Austria
    Biochem Biophys Res Commun 269:502-7. 2000
    ..p. The leptin-receptor-defective mice of this line might serve as a model for the investigation of genes modulating the development and mode of expression of diabetes...
  8. ncbi [Embryonic stem cells. Future perspectives]
    M Groebner
    Medizinische Klinik und Poliklinik I, ,
    Internist (Berl) 47:502, 504-8. 2006
    ..The first human clinical trial using ES cells will start in the United States this year...