Research Topics
| U ZiemannSummaryAffiliation: Frankfurt am Main Country: Germany Publications
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Publications
TMS induced plasticity in human cortexUlf Ziemann
Motor Cortex Laboratory, Department of Neurology, J W Goethe University Frankfurt, Frankfurt am Main, Germany
Rev Neurosci 15:253-66. 2004..This review focuses on RTMS induced changes in excitability, the potential mechanisms underlying these effects, and the usefulness of this knowledge to gain insight into mechanisms of other processes such as learning...- Mechanisms underlying mirror movements in Parkinson's disease: a transcranial magnetic stimulation studyMassimo Cincotta
Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy
Mov Disord 21:1019-25. 2006..These findings provide converging evidence that, in PD, MMs do not depend on unmasking of ipsilateral projections but are explained by motor output along the crossed corticospinal projection from the mirror M1... - Movement-related cortical potentials in patients with Machado-Joseph diseaseMing Kuei Lu
Neuroscience Laboratory, Department of Neurology, China Medical University Hospital, No 2, Yuh Der Road, Taichung 404, Taiwan
Clin Neurophysiol 119:1010-9. 2008..What is the Bereitschaftspotential? Clin Neurophysiol 2006;117:2341-56) were studied in patients with Machado-Joseph disease (MJD) to elucidate the pathophysiology of voluntary movement... - Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patientsSven Jarius
Neurocure, Charite University Medicine Berlin, Berlin, Germany
J Neuroinflammation 9:14. 2012..abstract:.. - Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)Hans Peter Tony
Department Medicine Rheumatology and Clinical Immunology, Charite Universitatsmedizin Berlin, Schumannstr 20 21, 10098 Berlin, Germany
Arthritis Res Ther 13:R75. 2011.... - Consensus: Motor cortex plasticity protocolsUlf Ziemann
Department Neurology, Goethe University Frankfurt, Germany
Brain Stimul 1:164-82. 2008.... - Estimated magnitude and interactions of cortico-motoneuronal and Ia afferent input to spinal motoneurones of the human handUlf Ziemann
Motor Cortex Laboratory, Clinic of Neurology, Johann Wolfgang Goethe University of Frankfurt, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
Neurosci Lett 364:48-52. 2004..The weights of these inputs may relate to the specific functions of the different intrinsic hand muscles in skilled finger movements... - Transcranial magnetic stimulation at the interface with other techniques: a powerful tool for studying the human cortexUlf Ziemann
Department of Neurology, Goethe University Frankfurt, Frankfurt am Main, Germany
Neuroscientist 17:368-81. 2011..This review provides an up-to-date synopsis of these combined approaches and highlights important examples that have advanced our understanding of how TMS interacts with neuronal networks in the human brain... - Pharmacology of TMSUlf Ziemann
Clinic of Neurology, J W Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt am Main, Germany
Suppl Clin Neurophysiol 56:226-31. 2003..Increasing numbers of different forms of cortical inhibition are being discovered, such as SICI (GABAA dependent), CSP (GABAB dependent) and SLAI (cholinergic), and it is very likely that more will follow soon... - Learning modifies subsequent induction of long-term potentiation-like and long-term depression-like plasticity in human motor cortexUlf Ziemann
Motor Cortex Laboratory, Clinic of Neurology, Johann Wolfgang Goethe University, D 60528 Frankfurt am Main, Germany
J Neurosci 24:1666-72. 2004..The same number of repeated slow thumb abduction movements did not result in learning and had no effects on PAS-induced plasticity. Findings support the view that learning in human M1 occurs through LTP-like mechanisms... - Pharmacological modulation of plasticity in the human motor cortexUlf Ziemann
Department of Neurology, J W Goethe University Frankfurt, Frankfurt am Main, Germany
Neurorehabil Neural Repair 20:243-51. 2006..It will be argued that these data may be useful for advancing the concepts of pharmacotherapy for recovery after stroke... - Cortico-motoneuronal excitation of three hand muscles determined by a novel penta-stimulation techniqueUlf Ziemann
Motor Cortex Laboratory, Department of Neurology, Johann Wolfgang Goethe University of Frankfurt, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
Brain 127:1887-98. 2004..The findings strongly suggest that CMS excitation differs between hand muscles and that these differences directly link to capability differences in individuated finger movements... - TMS and drugsUlf Ziemann
Motor Cortex Laboratory, Clinic of Neurology, Johann Wolfgang Goethe University Frankfurt, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
Clin Neurophysiol 115:1717-29. 2004..Finally, TMS or repetitive TMS by themselves may induce changes in endogenous neurotransmitters or neuromodulators. All these possible interactions are the focus of this in-depth review on TMS and drugs... - Modifying motor learning through gating and homeostatic metaplasticityUlf Ziemann
Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
Brain Stimul 1:60-6. 2008..This approach invokes homeostatic metaplasticity. Here we highlight how transcranial brain stimulation can exploit gating and homeostatic metaplasticity to enhance motor learning in healthy subjects and in patients after stroke... - LTP-like plasticity in human motor cortexUlf Ziemann
Department of Neurology, Johann Wolfgang Goethe University of Frankfurt, Schleusenweg 2-16, D-60528 Frankfurt am Main, Germany
Suppl Clin Neurophysiol 57:702-7. 2004 - Dual modulating effects of amphetamine on neuronal excitability and stimulation-induced plasticity in human motor cortexUlf Ziemann
Human Cortical Physiology Section, NINDS, National Institutes of Health, Building 10, Bethesda, MD 20892, USA
Clin Neurophysiol 113:1308-15. 2002..The objective of the present study is to test the modulating effects of dextro-amphetamine (d-AMP) on excitability and stimulation-induced plasticity in human motor cortex... - Hemispheric asymmetry of ipsilateral motor cortex activation during unimanual motor tasks: further evidence for motor dominanceU Ziemann
Clinic of Neurology, J W Goethe University, Theodor Stern Kai 7, D 60590, Frankfurt am Main, Germany
Clin Neurophysiol 112:107-13. 2001..To test to which extent the increase in ipsilateral motor cortex excitability during unimanual motor tasks shows hemispheric asymmetry... - Stimulation-induced within-representation and across-representation plasticity in human motor cortexUlf Ziemann
Human Cortical Physiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1428, USA
J Neurosci 22:5563-71. 2002..This bidirectional plasticity might be used for purposeful modulation of human cortical function... - Long-term potentiation (LTP)-like plasticity and learning in human motor cortex--investigations with transcranial magnetic stimulation (TMS)Ulf Ziemann
Motor Cortex Laboratory, Department of Neurology, Johann Wolfgang Goethe-University of Frankfurt, D-60528 Frankfurt am Main, Germany
Suppl Clin Neurophysiol 59:19-25. 2006 - Development of biomarkers for multiple sclerosis as a neurodegenerative disorderUlf Ziemann
Department of Neurology, Goethe University, Frankfurt am Main, Germany
Prog Neurobiol 95:670-85. 2011..This paper compiles an up-to-date critical review of the available knowledge of candidate biomarkers of neurodegenerative processes in MS... - Modulation of practice-dependent plasticity in human motor cortexU Ziemann
Clinic of Neurology, J W Goethe University, Schleusenweg 2 16, D 60590 Frankfurt am Main, Germany
Brain 124:1171-81. 2001..We propose that changes in GABA activity may be instrumented to modulate plasticity purposefully; for instance, to enhance plastic change and recovery of function after a lesion in neurological patients... - Dissociation of the pathways mediating ipsilateral and contralateral motor-evoked potentials in human hand and arm musclesU Ziemann
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA
J Physiol 518:895-906. 1999..Other pathways, such as branching of corticomotoneuronal axons, a transcallosal projection or a slow-conducting monosynaptic ipsilateral pathway are very unlikely or can be excluded... - Role of the human motor cortex in rapid motor learningW Muellbacher
Medical Neurology Branch, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1428, USA
Exp Brain Res 136:431-8. 2001..Since the changes in MEP amplitude were observed only after TMS of M1 but not after direct stimulation of the corticospinal tract, these findings indicate task- and effector-specific involvement of human M1 in rapid motor learning... - The alpha2-adrenergic agonist guanfacine reduces excitability of human motor cortex through disfacilitation and increase of inhibitionAlexei Korchounov
Clinic of Neurology, Johann Wolfgang Goethe-University Frankfurt, Theodor-Stern-Kai 7, D-60590, Frankfurt, Germany
Clin Neurophysiol 114:1834-40. 2003..These findings support the idea that anti-noradrenergic drugs are detrimental for cortical plasticity and learning which are down-regulated by disfacilitation or increased inhibition... - Physiology of modulation of motor cortex excitability by low-frequency suprathreshold repetitive transcranial magnetic stimulationG Heide
Department of Neurology, Friedrich Schiller University, Erlanger Allee 101, 07740 Jena, Germany
Exp Brain Res 171:26-34. 2006..Modulation of motor cortical inhibition did not play a role in explaining the rTMS induced changes in MEP amplitude... - Subtle hemispheric asymmetry of motor cortical inhibitory toneTihomir V Ilic
Clinic of Neurology, J.W. Goethe-University Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany
Clin Neurophysiol 115:330-40. 2004..This may put the M1-D to an advantage for processes that are associated with a reduction of SICI, such as voluntary activation and use-dependent plasticity... - Modulation of preparatory volitional motor cortical activity by paired associative transcranial magnetic stimulationMing Kuei Lu
Motor Cortex Group, Department of Neurology, Goethe University, Frankfurt am Main, Germany
Hum Brain Mapp 30:3645-56. 2009..Findings indicate a specific interference of PAS with preparatory volitional motor cortical activity, suggestive of a net result caused by increased M1 excitability and disrupted effective connectivity between premotor areas and M1... - Analogous corticocortical inhibition and facilitation in ipsilateral and contralateral human motor cortex representations of the tongueW Muellbacher
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-1428, USA
J Clin Neurophysiol 18:550-8. 2001..0001). These findings indicate that the ipsilateral and contralateral representations of the tongue are under analogous inhibitory and facilitatory control, possibly by a common intracortical network... - Demonstration of facilitatory I wave interaction in the human motor cortex by paired transcranial magnetic stimulationU Ziemann
Department of Clinical Neurophysiology, University of Gottingen, Human Motor Control Section, National Institutes of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
J Physiol 511:181-90. 1998..5. It is concluded that the MEP facilitation after paired TMS, at least for the first MEP peak, is due to facilitatory interaction between I waves, and takes place in the motor cortex at or upstream from the corticospinal neurone... - Complex modulation of human motor cortex excitability by the specific serotonin re-uptake inhibitor sertralineTihomir V Ilic
Department of Neurology, J.W. Goethe-University Frankfurt, Theodor-Stern-Kai 7, D-60590 Franfurt am Main, Germany
Neurosci Lett 319:116-20. 2002..These features may improve the signal-to-noise ratio of output cells in human motor cortex... - Hysteresis effects on the input-output curve of motor evoked potentialsCaroline Möller
Motor Cortex Group, Department of Neurology, Goethe University, Schleusenweg 2 16, 60528 Frankfurt am Main, Germany
Clin Neurophysiol 120:1003-8. 2009..Here we sought to determine hysteresis effects on IO curves, i.e. their short-term dependence on prior corticospinal activation... - Interference of short-interval intracortical inhibition (SICI) and short-interval intracortical facilitation (SICF)Sinikka H Peurala
Motor Cortex Group, Department of Neurology, Goethe University of Frankfurt, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
Clin Neurophysiol 119:2291-7. 2008..However, facilitatory processes may contaminate SICI under certain conditions. Here, we specifically address the contribution of short-interval intracortical facilitation (SICF)... - New graphical method to measure silent periods evoked by transcranial magnetic stimulationM A Garvey
Pediatric Movement Disorders Unit, Pediatrics and Developmental Neuropsychiatry Branch, NIMH, National Institutes of Health, 10 Center Drive, 4N208, MSC 1255, Bethesda, MD 20892 1255, USA
Clin Neurophysiol 112:1451-60. 2001..We describe a graphical method to measure silent periods with greater precision. The statistical process underlying this new method is simple and particularly suited to signal detection in serially dependent data... - Cortical correlates of neuromotor development in healthy childrenM A Garvey
Pediatric Movement Disorders Unit, Human Motor Control Section, Motor Neurology Branch, NINDS, National Institutes of Health, 10 Center Drive, 5N226, MSC 1428, Bethesda, MD 20982 1428, USA
Clin Neurophysiol 114:1662-70. 2003..To examine the relationship between acquisition of fine motor skills in childhood and development of the motor cortex... - Crossed reduction of human motor cortex excitability by 1-Hz transcranial magnetic stimulationE M Wassermann
Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1428, USA
Neurosci Lett 250:141-4. 1998..This demonstrates that rTMS can condition cortical excitability at a distance of one or more synapses and suggest that decreased excitability to TMS is a correlate of decreased blood flow and metabolism... - Differences of the ipsilateral silent period in small hand musclesPatrick Jung
Motor Cortex Laboratory, Department of Neurology, Johann Wolfgang Goethe University, Schleusenweg 2-16, Frankfurt am Main, Germany
Muscle Nerve 34:431-6. 2006..Therefore, for specific assessment of callosal conduction, the iSP should be measured in the APB rather than FDI... - Modification of motor cortical excitability by an acetylcholinesterase inhibitorAlexei Korchounov
Motor Cortex Laboratory, Department of Neurology, Johann Wolfgang Goethe-University of Frankfurt, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany
Exp Brain Res 164:399-405. 2005..The findings predict that acetylcholine has the potential to promote plasticity and learning in human motor cortex... - Homeostatic plasticity in human motor cortex demonstrated by two consecutive sessions of paired associative stimulationJ Florian M Müller
Motor Cortex Laboratory, Department of Neurology, Johann Wolfgang Goethe University, D 60528 Frankfurt am Main, Germany
Eur J Neurosci 25:3461-8. 2007..Because the two PAS sessions activate identical neuronal circuits, we conclude that 'homosynaptic-like' homeostatic mechanisms in accord with the BCM rule contribute to regulating plasticity in human M1... - Vasogenic edema in Bickerstaff's brainstem encephalitis: a serial MRI studyS Weidauer
Institute of Neuroradiology, University of Frankfurt, Frankfurt, Germany
Neurology 61:836-8. 2003..High apparent diffusion coefficient values imply a vasogenic rather than cytotoxic edema as the cause of the hyperintense signal changes on T2-weighted images... - Anthropometric approximation of body weight in unresponsive stroke patientsM W Lorenz
Johann Wolfgang Goethe University, Department for Neurology, Schleusenweg 2 16, D 60528 Frankfurt Main, Germany
J Neurol Neurosurg Psychiatry 78:1331-6. 2007..Instead, weight is estimated visually by the attending physician, but this is known to be inaccurate... - Acute neuropathy with multiple conduction blocks after TNFalpha monoclonal antibody therapyOliver C Singer
Department of Neurology, J.W. Goethe-University Frankfurt am Main, Schleusenweg 2-16, D-60528 Frankfurt/Main, Germany
Neurology 63:1754. 2004 - Improving hand function in chronic strokeWolf Muellbacher
Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Dr, Bldg 10, Room 5N226, Bethesda, MD 20892, USA
Arch Neurol 59:1278-82. 2002..CONCLUSION: This is a novel therapeutic strategy that may help improve hand function in patients with long-term weakness after stroke... - Interindividual variability and age-dependency of motor cortical plasticity induced by paired associative stimulationJ Florian M Müller-Dahlhaus
Motor Cortex Group, Department of Neurology, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528, Frankfurt am Main, Germany
Exp Brain Res 187:467-75. 2008..In conclusion, measures of motor cortical excitability (RMT, MEP(1 mV)) and age determine direction and magnitude of PAS effects in individual subjects... - Intraoperative motor evoked potential alteration in intracranial tumor surgery and its relation to signal alteration in postoperative magnetic resonance imagingAndrea Szelenyi
Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt, Germany
Neurosurgery 67:302-13. 2010.... - The ipsilateral silent period in boys with attention-deficit/hyperactivity disorderMarjorie A Garvey
Pediatric Movement Disorders Unit, Human Motor Control Section, MNB, NINDS, National Institutes of Health, Bethesda, MD 20892, USA
Clin Neurophysiol 116:1889-96. 2005..Characterize maturation of transcallosal inhibition (ipsilateral silent period [iSP]) in attention deficit/hyperactivity disorder (ADHD) using transcranial magnetic stimulation (TMS)... - Short latency afferent inhibition and facilitation in patients with writer's crampKirn R Kessler
Motor Cortex Laboratory, Department of Neurology, J W Goethe University, Frankfurt Main, Germany
Mov Disord 20:238-42. 2005..These findings suggest that somatosensory short-latency inhibitory input into the primary motor cortex is normal in WC, whereas a later excitatory input, which very likely reflects the long-latency reflex II, is exaggerated... - Modification of practice-dependent plasticity in human motor cortex by neuromodulatorsFrank Meintzschel
Motor Cortex Laboratory, Department of Neurology, J.W. Goethe-University Frankfurt, Schleusenweg 2-16, D-60528 Frankfurt am Main, Germany
Cereb Cortex 16:1106-15. 2006..Enhancement of plasticity occurred through different strategies that either favoured extrinsic (NE, ACh) or intrinsic (DA) modulating influence on the motor cortical output network... - Interactions between short-interval intracortical inhibition and short-latency afferent inhibition in human motor cortexHenrik Alle
Department of Neurology, Goethe University, Schleusenweg 2 16, 60528 Frankfurt am Main, Germany
J Physiol 587:5163-76. 2009..Furthermore, dominance of S1 over P is compatible with the notion that the SICI interneurons target the corticospinal neurons closer to their axon initial segment than the SAI interneurons... - Ipsilateral silent period: a marker of callosal conduction abnormality in early relapsing-remitting multiple sclerosis?Patrick Jung
Department of Neurology, Johann Wolfgang Goethe-University, Schleusenweg 2-16, D-60528 Frankfurt am Main, Germany
J Neurol Sci 250:133-9. 2006..ISP duration did not correlate with MRI abnormalities of the CC. CONCLUSIONS: ISP measures are neither a sensitive nor a specific marker of callosal conduction abnormality in early RRMS... - A practical guide to diagnostic transcranial magnetic stimulation: report of an IFCN committeeS Groppa
Department of Neurology, Christian Albrechts University, Kiel, Germany
Clin Neurophysiol 123:858-82. 2012..Additional sections cover safety issues, the triple stimulation technique, and neuropediatric aspects of TMS... - Multimodal evoked potentials measure and predict disability progression in early relapsing-remitting multiple sclerosisP Jung
Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
Mult Scler 14:553-6. 2008..39, p < 0.02). The data suggest that serial mEPS measure and moderately predict clinically relevant disease activity in the therapeutically most relevant early stage of RRMS... - Mechanisms underlying human motor system plasticityB Boroojerdi
Human Cortical Physiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 5N 234, 10 Center Drive, MSC 1428, Bethesda, Maryland 20892-1428, USA
Muscle Nerve 24:602-13. 2001..In this review, we describe paradigms used to study mechanisms of plasticity in the intact human motor system, the functional relevance of such plasticity, and possible ways to modulate it... - TMS-assisted neurophysiological profiling of the dopamine receptor agonist cabergoline in human motor cortexA Korchounov
Motor Cortex Laboratory, Department of Neurology, Johann Wolfgang Goethe University of Frankfurt, Frankfurt am Main, Germany
J Neural Transm 114:223-9. 2007..This shift in the balance from excitation to inhibition may assist, by improving the 'signal-to-noise ratio' in motor cortex, in the positive modulating effect of cabergoline on practice-dependent plasticity... - Interhemispheric motor inhibition: its role in controlling electromyographic mirror activityAnnemarie Hübers
Motor Cortex Group, Department of Neurology, Goethe University, D 60528 Frankfurt am Main, Germany
Eur J Neurosci 28:364-71. 2008..These results provide strong and consistent evidence that transcallosal inhibitory interhemispheric interaction provides a significant route by which unwanted MA during intended unimanual motor tasks can be controlled... - Rapid modulation of GABA in sensorimotor cortex induced by acute deafferentationLucien M Levy
Neuroimaging Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, 5D20, Bethesda, MD 20892, USA
Ann Neurol 52:755-61. 2002..Reduction of brain GABA can play a pivotal role in regulating the extent of rapid cortical reorganization after lesions or changes in sensory input... - Transitions between dynamical states of differing stability in the human brainAndreas Meyer-Lindenberg
Clinical Brain Disorders Branch, National Institute of Mental Health, and Human Cortical Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 99:10948-53. 2002.... - Early consolidation in human primary motor cortexWolf Muellbacher
Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bldg 10, Rm 5N226, 10 Center Drive MSC 1428, Bethesda, Maryland 20892-1428, USA
Nature 415:640-4. 2002..These findings indicate that the human M1 is specifically engaged during the early stage of motor consolidation... - Homeostatic and nonhomeostatic modulation of learning in human motor cortexPatrick Jung
Department of Neurology, Goethe University Frankfurt, 60528 Frankfurt am Main, Germany
J Neurosci 29:5597-604. 2009..The present findings demonstrate that motor learning in humans can be modulated by noninvasive brain stimulation and suggest the possibility of enhancing motor relearning in defined neurological patients... - The human motor corpus callosumMathias Wahl
Department of Neurology, Goethe University, Frankfurt am Main, Germany
Rev Neurosci 19:451-66. 2008..This review surveys current knowledge about the human motor CC, with a focus on recent studies which assessed the motor CC by multimodal advanced neurophysiological and neuroimaging techniques... - Human motor corpus callosum: topography, somatotopy, and link between microstructure and functionMathias Wahl
Department of Neurology, Johann Wolfgang Goethe University of Frankfurt, D 60528 Frankfurt am Main, Germany
J Neurosci 27:12132-8. 2007.... - Inhibitory circuits and the nature of their interactions in the human motor cortex a pharmacological TMS studyJ Florian
Motor Cortex Group, Department of Neurology, Johann Wolfgang Goethe University, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
J Physiol 586:495-514. 2008..It will be argued that the negative interactions between SIHI and SICI, LICI and SIHI, and LICI and SICI are most likely due to presynaptic GABA B R-mediated autoinhibition... - The role of GABA(B) receptors in intracortical inhibition in the human motor cortexMichelle N McDonnell
Research Centre for Human Movement Control, The University of Adelaide, Adelaide, Australia
Exp Brain Res 173:86-93. 2006..The increase in LICI is likely to be a result of increased GABA(B) receptor mediated inhibitory post-synaptic potentials, while the reduction in SICI may relate to the activation of pre-synaptic GABA(B) receptors reducing GABA release... - Exploring motor cortical plasticity using transcranial magnetic stimulation in humansTihomir V Ilic
Clinic of Neurology, Military Medical Academy, Belgrade, Serbia and Montenegro
Ann N Y Acad Sci 1048:175-84. 2005..Purposeful modulation of motor cortical plastic changes by manipulative TMS protocols may offer useful rehabilitative strategies in patients with chronic motor deficits... - Dissociated effects of diazepam and lorazepam on short-latency afferent inhibitionVincenzo Di Lazzaro
Istituto di Neurologia, Universita Cattolica, L go A Gemelli 8, 00168 Rome, Italy
J Physiol 569:315-23. 2005..This dissociation suggests, for the first time, that TMS measures of cortical inhibition provide the opportunity to segregate differences of benzodiazepine action in human central nervous system circuits... - Improving disability in stroke with RTMSUlf Ziemann
Lancet Neurol 4:454-5. 2005 - Separate ipsilateral and contralateral corticospinal projections in congenital mirror movements: Neurophysiological evidence and significance for motor rehabilitationMassimo Cincotta
Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy
Mov Disord 18:1294-300. 2003..A marked reduction of MM was observed after training, suggesting that unwanted mirror activity in the ipsilateral pathway can be suppressed by learning... - Functional connectivity between secondary and primary motor areas underlying hand-foot coordinationWinston D Byblow
Movement Neuroscience Laboratory, University of Auckland, Auckland, New Zealand
J Neurophysiol 98:414-22. 2007..These results may have implications for targeted neurorehabilitation after stroke... - Homeostatic metaplasticity in the human somatosensory cortexBarbara Bliem
Ruhr University Bochum, Germany
J Cogn Neurosci 20:1517-28. 2008..These interactions demonstrate that homeostatic metaplasticity operates in the human somatosensory cortex, controlling both cortical excitability and somatosensory skill... - The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committeeRobert Chen
Division of Neurology, Toronto Western Research Institute, University of Toronto, 7MC411, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ont, Canada M5T 2S8
Clin Neurophysiol 119:504-32. 2008..TMS measures have potential clinical utility in cerebellar disease, dementia, facial nerve disorders, movement disorders, stroke, epilepsy, migraine and chronic pain... - Involvement of the human dorsal premotor cortex in unimanual motor control: an interference approach using transcranial magnetic stimulationMassimo Cincotta
U O di Neurologia, Azienda Sanitaria di Firenze, Ospedale S Maria Nuova, Piazza S Maria Nuova, 1, 50122 Firenze, Italy
Neurosci Lett 367:189-93. 2004..Findings suggest that activity in the dPMC contributes to the suppression of mirror movements during intended unilateral movements... - Cortical inhibition and excitation in abstinent cocaine-dependent patients: a transcranial magnetic stimulation studyKarthik Sundaresan
Department of Psychiatry and Behavioral Neurosciences, School of Medicine, Wayne State University, USA
Neuroreport 18:289-92. 2007..Although the increase in long-interval intracortical facilitation suggests exaggerated cortical glutamatergic excitability, the increase in resting motor threshold may signify a protective mechanism against seizures and psychosis... - Suppression of LTP-like plasticity in human motor cortex by the GABAB receptor agonist baclofenMichelle N McDonnell
Research Centre for Human Movement Control, The University of Adelaide, Adelaide, Australia
Exp Brain Res 180:181-6. 2007..This suggests that increased GABAB mediated inhibitory postsynaptic potentials drive this effect, and that baclofen may have a negative impact on LTP-dependent behavioural processes such as motor learning... - Deafferentation of neighbouring motor cortex areas does not further enhance saturated practice-dependent plasticity in healthy adultsMichael Walther
Department of Neuropediatrics and Muscle Disorders, University Children s Hospital, Freiburg, Germany
Clin Neurophysiol 119:886-91. 2008..To assess effects of deafferentation of the arm representation of primary motor cortex (M1) on practice-dependent plasticity in healthy adults... - Myoclonus-dystonia syndrome: epsilon-sarcoglycan mutations and phenotypeFriedrich Asmus
Neurologische Klinik Grosshadern, Ludwig Maximilians Universitat, Munich, Germany
Ann Neurol 52:489-92. 2002..Six novel and one previously known heterozygous SGCE mutations were identified. SGCE deficiency seems to be the common pathogenetic mechanism in myoclonus-dystonia syndrome... - TMS for ALS: why and why notUlf Ziemann
Clin Neurophysiol 115:1237-8. 2004 - GABAA receptor subtype specific enhancement of inhibition in human motor cortexVincenzo Di Lazzaro
Istituto di Neurologia, Universita Cattolica, L go A Gemelli 8, 00168 Rome, Italy
J Physiol 575:721-6. 2006.... - Surface electromyography shows increased mirroring in Parkinson's disease patients without overt mirror movementsMassimo Cincotta
Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy
Mov Disord 21:1461-5. 2006..Our findings suggest that dysfunction of unimanual motor control is a general feature of PD. It is likely that this deficient movement lateralization contributes to an impairment of nonsymmetrical bimanual movements in PD...