Xiaomin Zheng

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. ncbi BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility
    Xiaomin Zheng
    Laboratory for Tumor Stem Cell Biology, Department of Hematology, J W Goethe University, Frankfurt, Germany
    BMC Cancer 6:262. 2006
  2. ncbi Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells
    Xiaomin Zheng
    Laboratory of Tumor Stem Cell Biology, Department of Hematology, J W Goethe University, Frankfurt, Germany
    Haematologica 92:323-31. 2007
  3. ncbi Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment
    Xiaomin Zheng
    Department of Hematology, Laboratory for Tumor Stem Cell Biology, Goethe University, Frankfurt, Germany
    PLoS ONE 4:e7661. 2009
  4. ncbi The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha
    Elena Puccetti
    Department of Hematology, Johann Wolfgang Goethe Universitat, Frankfurt, Germany
    Cancer Res 65:6080-8. 2005
  5. ncbi Cooperation between constitutively activated c-Kit signaling and leukemogenic transcription factors in the determination of the leukemic phenotype in murine hematopoietic stem cells
    Xiaomin Zheng
    Laboratory of Tumor Stem Cell Biology, Department of Hematology, Goethe University, D 60596 Frankfurt, Germany
    Int J Oncol 34:1521-31. 2009
  6. ncbi Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells
    Gesine Bug
    , , Frankfurt, Germany
    Cancer Res 65:2537-41. 2005
  7. ncbi Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells
    Xiaomin Zheng
    Medizinische Klinik III Abteilung Hämatologie, Laboratorium für Experimentelle Hämatolgie, Johan Wolfgang Goethe Universität Frankfurt, Germany
    Blood 103:3535-43. 2004
  8. ncbi [Mitochondrial DNA mutations and non-syndromic sensorineural hearing loss]
    Weijia Kong
    Department of Otorhinolaryngology, Union Hospital of Tongji Medical School, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhonghua Er Bi Yan Hou Ke Za Zhi 37:338-42. 2002

Detail Information

Publications8

  1. ncbi BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility
    Xiaomin Zheng
    Laboratory for Tumor Stem Cell Biology, Department of Hematology, J W Goethe University, Frankfurt, Germany
    BMC Cancer 6:262. 2006
    ..We, therefore, compared the function of the ABL/BCR proteins with that of wild-type BCR...
  2. ncbi Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells
    Xiaomin Zheng
    Laboratory of Tumor Stem Cell Biology, Department of Hematology, J W Goethe University, Frankfurt, Germany
    Haematologica 92:323-31. 2007
    ..Arsenic induces high rates of CR and CMR followed by a long relapse-free survival (RFS). Here we compared the effects of ATRA and arsenic on PML/RARalpha-positive stem cell compartments...
  3. ncbi Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment
    Xiaomin Zheng
    Department of Hematology, Laboratory for Tumor Stem Cell Biology, Goethe University, Frankfurt, Germany
    PLoS ONE 4:e7661. 2009
    ..Herein, we investigated the leukemogenic potential of the der9-associated p96(ABL/BCR) and p40(ABL/BCR) fusion proteins and their roles in the lineage commitment of hematopoietic stem cells in comparison to BCR/ABL...
  4. ncbi The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha
    Elena Puccetti
    Department of Hematology, Johann Wolfgang Goethe Universitat, Frankfurt, Germany
    Cancer Res 65:6080-8. 2005
    ..Taken together, these data provide evidence that the dimerization capacity and the formation of a functionally charged pocket are indispensable for the PLZF/RARalpha-induced leukemogenesis...
  5. ncbi Cooperation between constitutively activated c-Kit signaling and leukemogenic transcription factors in the determination of the leukemic phenotype in murine hematopoietic stem cells
    Xiaomin Zheng
    Laboratory of Tumor Stem Cell Biology, Department of Hematology, Goethe University, D 60596 Frankfurt, Germany
    Int J Oncol 34:1521-31. 2009
    ..Our data provide evidence that c-Kit does not have to be mutated to contribute to the determination of the leukemic phenotype in AML...
  6. ncbi Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells
    Gesine Bug
    , , Frankfurt, Germany
    Cancer Res 65:2537-41. 2005
    ....
  7. ncbi Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells
    Xiaomin Zheng
    Medizinische Klinik III Abteilung Hämatologie, Laboratorium für Experimentelle Hämatolgie, Johan Wolfgang Goethe Universität Frankfurt, Germany
    Blood 103:3535-43. 2004
    ..These data provide the first evidence that the aberrant activation of Wnt signaling by the AATP decisively contributes to the pathogenesis of AML...
  8. ncbi [Mitochondrial DNA mutations and non-syndromic sensorineural hearing loss]
    Weijia Kong
    Department of Otorhinolaryngology, Union Hospital of Tongji Medical School, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhonghua Er Bi Yan Hou Ke Za Zhi 37:338-42. 2002
    ....