Andreas Raabe

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. ncbi [D-Val22]big ET-1[16-38] inhibits endothelin-converting enzyme activity: a promising concept in the prevention of cerebral vasospasm
    Michael Zimmermann
    Department of Neurosurgery, University of Frankfurt Main, Schleusenweg 2 16, 60528 Frankfurt, Germany
    Neurosurg Rev 26:125-32. 2003
  2. ncbi Prospective evaluation of surgical microscope-integrated intraoperative near-infrared indocyanine green videoangiography during aneurysm surgery
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 103:982-9. 2005
  3. ncbi [Recommendations for the management of unruptured intracranial aneurysms]
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Johann Wolfgang Goethe Universität Frankfurt am Main
    Zentralbl Neurochir 63:70-6. 2002
  4. ncbi [Recommendations for the management of patients with aneurysmal subarachnoid hemorrhage]
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Klinikum der Johann Wolfgang Goethe Universität Frankfurt am Main, Germany
    Zentralbl Neurochir 66:79-91. 2005
  5. ncbi [Frame-less and frame-based stereotaxy? How to choose the appropriate procedure]
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Johann Wolfgang Goethe Universitat, Frankfurt am Main
    Zentralbl Neurochir 64:1-5. 2003
  6. ncbi Measurements of serum S-100B protein: effects of storage time and temperature on pre-analytical stability
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Clin Chem Lab Med 41:700-3. 2003
  7. ncbi German Society of Neurosurgery Section on Vascular Neurosurgery: Position Statement on the International Subarachnoid Hemorrhage Trial (ISAT)
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Johann Wolfgang Goethe Universität Frankfurt am Main, Germany
    Zentralbl Neurochir 64:99-103. 2003
  8. ncbi Laser surface scanning for patient registration in intracranial image-guided surgery
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 50:797-801; discussion 802-3. 2002
  9. ncbi Serum S-100B protein as a molecular marker in severe traumatic brain injury
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Restor Neurol Neurosci 21:159-69. 2003
  10. ncbi Three-dimensional rotational angiography guidance for aneurysm surgery
    Andreas Raabe
    Department of Neurosurgery, Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    J Neurosurg 105:406-11. 2006

Detail Information

Publications95

  1. ncbi [D-Val22]big ET-1[16-38] inhibits endothelin-converting enzyme activity: a promising concept in the prevention of cerebral vasospasm
    Michael Zimmermann
    Department of Neurosurgery, University of Frankfurt Main, Schleusenweg 2 16, 60528 Frankfurt, Germany
    Neurosurg Rev 26:125-32. 2003
    ..Therefore, further studies of the biochemical nature of cerebrovascular ECE activity are required...
  2. ncbi Prospective evaluation of surgical microscope-integrated intraoperative near-infrared indocyanine green videoangiography during aneurysm surgery
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 103:982-9. 2005
    ..The authors prospectively compared a new technique of surgical microscope-based indocyanine green (ICG) videoangiography with intraoperative or postoperative digital subtraction (DS) angiography...
  3. ncbi [Recommendations for the management of unruptured intracranial aneurysms]
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Johann Wolfgang Goethe Universität Frankfurt am Main
    Zentralbl Neurochir 63:70-6. 2002
    ..The present recommendations have been developed as a neurosurgical, neuroradiological and neurological consensus. They are based on the existing data of both treatment risks and the risks of the natural history of UIAs...
  4. ncbi [Recommendations for the management of patients with aneurysmal subarachnoid hemorrhage]
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Klinikum der Johann Wolfgang Goethe Universität Frankfurt am Main, Germany
    Zentralbl Neurochir 66:79-91. 2005
    ..Clinical data indicate that current prophylaxis and treatment of cerebral vasospasm is still insufficient and aggressive triple-H-therapy is associated with an increased incidence of complications...
  5. ncbi [Frame-less and frame-based stereotaxy? How to choose the appropriate procedure]
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Johann Wolfgang Goethe Universitat, Frankfurt am Main
    Zentralbl Neurochir 64:1-5. 2003
    ..Therefore, the size of the lesion should exceed 10 mm for punction and biopsy with a frameless system. Frame-based stereotaxy remains the gold standard for accurate targeting of lesions < 10 mm and for functional procedures...
  6. ncbi Measurements of serum S-100B protein: effects of storage time and temperature on pre-analytical stability
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Clin Chem Lab Med 41:700-3. 2003
    ..Therefore, blood samples may be collected as part of the daily clinical routine without time constraint and even stored overnight without affecting S-100B serum levels when measured with the LIAISON Sangtec 100 assay...
  7. ncbi German Society of Neurosurgery Section on Vascular Neurosurgery: Position Statement on the International Subarachnoid Hemorrhage Trial (ISAT)
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Johann Wolfgang Goethe Universität Frankfurt am Main, Germany
    Zentralbl Neurochir 64:99-103. 2003
    ..Therefore, we await with interest the angiographic and clinical follow-up data that will provide evidence about the final patient outcome...
  8. ncbi Laser surface scanning for patient registration in intracranial image-guided surgery
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 50:797-801; discussion 802-3. 2002
    ..We performed a prospective study to measure the calculated registration error and the application accuracy of laser surface registration for intracranial image-guided surgery in the clinical setting...
  9. ncbi Serum S-100B protein as a molecular marker in severe traumatic brain injury
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Restor Neurol Neurosci 21:159-69. 2003
    ..In this paper, we summarize the current knowledge about S-100B serum measurements in severe head injury and address actual controversies...
  10. ncbi Three-dimensional rotational angiography guidance for aneurysm surgery
    Andreas Raabe
    Department of Neurosurgery, Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    J Neurosurg 105:406-11. 2006
    ..The aim of this study was to investigate the feasibility of integrating three-dimensional rotational angiography (3D-RA) data into a surgical navigation system and to assess its accuracy and potential clinical benefit...
  11. ncbi Technique and image quality of intraoperative indocyanine green angiography during aneurysm surgery using surgical microscope integrated near-infrared video technology
    A Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Zentralbl Neurochir 66:1-6; discussion 7-8. 2005
    ..We hypothesized that ICG angiography permits a simple and quick intraoperative assessment of vessel patency and aneurysm occlusion after clip placement...
  12. ncbi Protein S-100B as a serum marker of brain damage in severe head injury: preliminary results
    A Raabe
    Department of Neurosurgery, University of Leipzig, Germany
    Neurosurg Rev 23:136-8. 2000
    ....
  13. ncbi [Practice of perioperative thromboembolic prophylaxis in neurosurgery: results of a German survey]
    A Raabe
    Klinik und Poliklinik fur Neurochirurgie, Universitat Leipzig
    Zentralbl Neurochir 61:103-10. 2000
    ..In our survey a high rate of perioperative use of pharmacological thromboembolic prophylaxis was found. However, given the data from the literature, the optimum protocol remains unclear...
  14. ncbi Relative importance of hypertension compared with hypervolemia for increasing cerebral oxygenation in patients with cerebral vasospasm after subarachnoid hemorrhage
    Andreas Raabe
    Department of Neurosurgery, Neurocenter Frankfurt, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 103:974-81. 2005
    ....
  15. ncbi S-100B protein as a serum marker of secondary neurological complications in neurocritical care patients
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University of Frankfurt am Main, Germany
    Neurol Res 26:440-5. 2004
    ..The major finding of our study was the influence of serial S-100B measurement on actual management of the patient in 21% of cases with neurological complications...
  16. ncbi Near-infrared indocyanine green video angiography: a new method for intraoperative assessment of vascular flow
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University Frankfurt am Main, Frankfurt am Main, Germany
    Neurosurgery 52:132-9; discussion 139. 2003
    ....
  17. ncbi Risk of shunt-dependent hydrocephalus after occlusion of ruptured intracranial aneurysms by surgical clipping or endovascular coiling: a single-institution series and meta-analysis
    Jean G de Oliveira
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 61:924-33; discussion 933-4. 2007
    ..To compare the risk of shunt-dependent hydrocephalus after treatment of ruptured intracranial aneurysms by clipping versus coiling...
  18. ncbi Time course in the development of cerebral vasospasm after experimental subarachnoid hemorrhage: clinical and neuroradiological assessment of the rat double hemorrhage model
    Hartmut Vatter
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt, Germany
    Neurosurgery 58:1190-7; discussion 1190-7. 2006
    ..Additionally, perfusion weighted imaging (PWI) at 3 tesla magnetic resonance (MR) tomography was implemented to assess the reduction in cerebral blood flow (CBF)...
  19. doi Trigonal and peritrigonal lesions of the lateral ventricle-surgical considerations and outcome analysis of 20 patients
    Fernando Ruiz Juretschke
    Department of Neurosurgery, Goethe University Frankfurt Main, Frankfurt Main, Germany
    Neurosurg Rev 33:457-64. 2010
    ..Even large trigonal lesions can be resected with low morbidity using a transcortical approach depending on the peritrigonal extension of the tumor...
  20. ncbi Characterization of the endothelin-B receptor expression and vasomotor function during experimental cerebral vasospasm
    Hartmut Vatter
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 60:1100-8; discussion 1108-9. 2007
    ..The aim of the present investigation is, therefore, to characterize the function and the expression of the ET(B) receptor in the cerebrovasculature during CVS...
  21. ncbi Effects of balloon angioplasty on perfusion- and diffusion-weighted magnetic resonance imaging results and outcome in patients with cerebral vasospasm
    Jürgen Beck
    Department of Neurosurgery and Institute of Neuroradiology, Johann Wolfgang Goethe University, Frankfurt, Germany
    J Neurosurg 105:220-7. 2006
    ....
  22. ncbi Assessment of flow in perforating arteries during intracranial aneurysm surgery using intraoperative near-infrared indocyanine green videoangiography
    Jean G de Oliveira
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 61:63-72; discussion 72-3. 2007
    ..In addition, we analyzed the incidence of perforating vessels involved during the aneurysm surgery and the incidence of ischemic infarct caused by compromised small arteries...
  23. ncbi Effect of delayed cerebral vasospasm on cerebrovascular endothelin A receptor expression and function
    Hartmut Vatter
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 107:121-7. 2007
    ..Therefore, the aim in the present study was to characterize these alterations, with the emphasis on the ET(A) receptor...
  24. doi Subarachnoid hemorrhage and intracerebral hematoma: incidence, prognostic factors, and outcome
    Erdem Güresir
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 63:1088-93; discussion 1093-4. 2008
    ..To analyze the incidence and impact of an intracerebral hematoma (ICH) on treatment and outcome in patients with aneurysmal subarachnoid hemorrhage...
  25. ncbi Functional magnetic resonance imaging-integrated neuronavigation: correlation between lesion-to-motor cortex distance and outcome
    Rene Krishnan
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 55:904-14; discusssion 914-5. 2004
    ..However, the clinical value remains to be defined. In this study, we investigated the correlation between the lesion-to-fMRI activation distance and the occurrence of a new postoperative deficit...
  26. ncbi Alteration of the cerebrovascular function of endothelin B receptor after subarachnoidal hemorrhage in the rat
    Juergen Konczalla
    Department of Neurosurgery, Institute of Neuroradiology, Johann Wolfgang Goethe University, D 60528 Frankfurt am Main, Germany
    Exp Biol Med (Maywood) 231:1064-8. 2006
    ..The present data indicate the loss of the ET(B) receptor-mediated relaxation of the cerebral arteries in cases of CVS, which is independent of the endothelial nitric oxide synthase level...
  27. doi Perfusion-diffusion mismatch in MRI to indicate endovascular treatment of cerebral vasospasm after subarachnoid haemorrhage
    Hartmut Vatter
    Department of Neurosurgery, Goethe University, Schleusenweg, 2 16, Frankfurt Main D 60528, Germany
    J Neurol Neurosurg Psychiatry 82:876-83. 2011
    ..Therefore, an MR based perfusion weighted imaging/diffusion weighted imaging (PWI/DWI) mismatch was used to indicate this treatment and to characterise its effectiveness...
  28. doi Histological evidence of delayed ischemic brain tissue damage in the rat double-hemorrhage model
    Erdem Güresir
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurol Sci 293:18-22. 2010
    ..Accordingly, our data suggest that the rat double-SAH model may be suitable to mimic delayed ischemic brain damage due to CVS and to investigate the neuroprotective effects of drugs...
  29. doi Unsecured intracranial aneurysms and induced hypertension in cerebral vasospasm: is induced hypertension safe?
    Johannes Platz
    Department of Neurosurgery, Johann Wolfgang Goethe University Hospital, Frankfurt am Main, Germany
    Neurocrit Care 14:168-75. 2011
    ..The aim of this study was to investigate the impact of induced hypertension on the rupturing of unsecured aneurysms in treating CVS...
  30. ncbi Post-operative hematoma after surgery for intracranial meningiomas: causes, avoidable risk factors and clinical outcome
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurol Res 26:61-6. 2004
    ..Extending coagulation tests and specific replacement therapy may prevent hematoma formation and improve the patients outcome...
  31. ncbi Risk of postoperative hemorrhage after intracranial surgery after early nadroparin administration: results of a prospective study
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 53:1028-34; discussion 1034-5. 2003
    ....
  32. pmc Postoperative nadroparin administration for prophylaxis of thromboembolic events is not associated with an increased risk of hemorrhage after spinal surgery
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528 Frankfurt Main, Germany
    Eur Spine J 13:9-13. 2004
    ..To determine the risk of postoperative hemorrhage during a 3-year period of early postoperative administration of nadroparin (Fraxiparin) plus compression stockings in a large cohort of patients who underwent spinal surgery...
  33. doi Decompressive craniectomy in subarachnoid hemorrhage
    Erdem Güresir
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurg Focus 26:E4. 2009
    ..The aim of this study was to analyze decompressive craniectomy (DC) in the setting of subarachnoid hemorrhage (SAH) with bleeding, infarction, or brain swelling as the underlying pathology in a large cohort of consecutive patients...
  34. doi Rapid closure technique in decompressive craniectomy
    Erdem Güresir
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 114:954-60. 2011
    ..The object of this study was to describe the rapid closure technique in decompressive craniectomy without duraplasty and its use in a large cohort of consecutive patients...
  35. ncbi Cerebrovascular characterization of clazosentan, the first nonpeptide endothelin receptor antagonist shown to be clinically effective for the treatment of cerebral vasospasm. Part II: effect on endothelin(B) receptor-mediated relaxation
    Hartmut Vatter
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main
    J Neurosurg 102:1108-14. 2005
    ..The aim of the present study was to define the actual selectivity of clazosentan, the first putative highly ET(A) receptor-selective antagonist clinically proven to be effective in the treatment of vasospasm in the cerebrovasculature...
  36. doi Intracranial pressure pulse amplitude during changes in head elevation: a new parameter for determining optimum cerebral perfusion pressure?
    Felix Mahfoud
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 152:443-50. 2010
    ..Therefore, it may be possible to draw conclusions from the ICPPA onto the cerebrovascular resistance (CVR) and thus the relative change in cerebral perfusion pressure (CPP)...
  37. ncbi Characterization of the potent combined endothelin(A/B)-antagonist PD 142893 on cerebral vessels
    Michael Zimmermann
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt, Germany
    Neurol Res 26:692-7. 2004
    ..The ET(B)-dependent relaxation of the cerebrovasculature is inhibited by PD 142893 at least in a comparable amount of contraction...
  38. ncbi Actual aspects of image-guided surgery
    Andreas Raabe
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Surg Technol Int 11:314-9. 2003
    ..Moreover, integration of other imaging modalities is becoming an increasingly used feature and provides useful information during surgery...
  39. ncbi Brain surface reformatted images for fast and easy localization of perirolandic lesions
    Elke Hattingen
    Institute of Neuroradiology, Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 102:302-10. 2005
    ....
  40. ncbi Size and location of ruptured and unruptured intracranial aneurysms measured by 3-dimensional rotational angiography
    Jürgen Beck
    Department of Neurosurgery, Johann Wolfgang Goethe University, 60528 Frankfurt am Main, Germany
    Surg Neurol 65:18-25; discussion 25-7. 2006
    ....
  41. ncbi The influence of barometric pressure changes and standard meteorological variables on the occurrence and clinical features of subarachnoid hemorrhage
    Matthias Setzer
    Department of Neurosurgery, Johann Wolfgang Goethe University, 60526 Frankfurt Main, Germany
    Surg Neurol 67:264-72; discussion 272. 2007
    ..The purpose of this study was to examine a possible association between standard meteorological variables and their changes and the occurrence and clinical features of SAH...
  42. doi Management, risk factors and outcome of cranial dural arteriovenous fistulae: a single-center experience
    Stephan Dützmann
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 153:1273-81. 2011
    ..Our objective was to evaluate the management of patients with intracranial DAVFs treated in our institution to identify the parameters that may help guide the long-term management of these lesions...
  43. pmc Treatment related morbidity of unruptured intracranial aneurysms: results of a prospective single centre series with an interdisciplinary approach over a 6 year period (1999-2005)
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528 Frankfurt Main, Germany
    J Neurol Neurosurg Psychiatry 78:864-71. 2007
    ..To review the angiographic and clinical outcome of patients with unruptured intracranial aneurysm(s) (UIA) with regard to complications and successful obliteration by surgical clipping or endovascular coiling...
  44. doi Thrombophilic risk factors in patients with cranial and spinal dural arteriovenous fistulae
    Ruediger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 63:693-98; discussion 698-9. 2008
    ..Therefore, the objective of this study is to compare thrombophilic risk factors in patients with cDAVF and sDAVF with no history of trauma...
  45. ncbi Automated fiducial marker detection for patient registration in image-guided neurosurgery
    Rene Krishnan
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Comput Aided Surg 8:17-23. 2003
    ..The influence of adjustable values for accuracy and threshold on the sensitivity and specificity of the detection process, as well as the time gain, was investigated...
  46. ncbi Effect of intraventricular sodium nitroprusside on cerebral hemodynamics and oxygenation in poor-grade aneurysm patients with severe, medically refractory vasospasm
    Andreas Raabe
    Department of Neurosurgery and Neurosurgery Center, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 50:1006-13; discussion 1013-4. 2002
    ....
  47. ncbi Comparison between clipping and coiling on the incidence of cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis
    Jean G de Oliveira
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurg Rev 30:22-30; discussion 30-1. 2007
    ..According to the available data, there is no significant difference between the types of technique used for aneurysm occlusion (clipping or coiling) on the risk of cerebral vasospasm development and its consequences...
  48. ncbi Increased incidence of thrombophilic abnormalities in patients with cranial dural arteriovenous fistulae
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528 Frankfurt Main, Germany
    Neurol Res 25:745-8. 2003
    ..Therefore in patients with cranial DAVF thrombophilic abnormalities should be considered in the post-operative/post-interventional management...
  49. ncbi Persistence of the nitric oxide-dependent vasodilator pathway of cerebral vessels after experimental subarachnoid hemorrhage
    Hartmut Vatter
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt, Germany
    Neurosurgery 60:179-87; discussion 187-8. 2007
    ..Therefore, the aim of the present investigation was to characterize this pathway on cerebral arteries during CVS...
  50. ncbi Sentinel headache and the risk of rebleeding after aneurysmal subarachnoid hemorrhage
    Jürgen Beck
    Department of Neurosurgery, Institute of Neuroradiology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Stroke 37:2733-7. 2006
    ..The clinical significance of sentinel headaches in patients with subarachnoid hemorrhage (SAH) is still unknown. We investigated whether patients with a sentinel headache (SH) have a higher rate of rebleeding after SAH...
  51. ncbi Cerebrovascular characterization of clazosentan, the first nonpeptide endothelin receptor antagonist clinically effective for the treatment of cerebral vasospasm. Part I: inhibitory effect on endothelin(A) receptor-mediated contraction
    Hartmut Vatter
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main
    J Neurosurg 102:1101-7. 2005
    ..The aim of the present investigation was, therefore, to define the pharmacological properties of clazosentan that affect ET(A) receptor-mediated contraction in the cerebrovasculature...
  52. ncbi Increased risk for postoperative hemorrhage after intracranial surgery in patients with decreased factor XIII activity: implications of a prospective study
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Stroke 33:1618-23. 2002
    ..The objective of this prospective study was to determine the incidence and clinical relevance of perioperative decreased factor XIII with respect to standard coagulation parameters and the occurrence of postoperative hematoma...
  53. ncbi Mutations in the lysyl oxidase gene not associated with intracranial aneurysm in central European families
    Anne Hofer
    Clinic for Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Cerebrovasc Dis 18:189-93. 2004
    ....
  54. doi A standardized protocol for the prevention of clinically relevant venous air embolism during neurosurgical interventions in the semisitting position
    Senol Jadik
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 64:533-8; discussion 538-9. 2009
    ..We report the results and complications associated with standardized intraoperative management designed for the prevention of hemodynamically relevant venous air embolism during surgery performed in the semisitting position...
  55. ncbi Contemporary management of aneurysmal subarachnoid hemorrhage in germany: results of a survey among 100 neurosurgical departments
    Oliver W Sakowitz
    Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany
    Neurosurgery 58:137-45; discussion 137-45. 2006
    ..In addition to preferences in vascular treatment (i.e., surgical versus endovascular), the choice of diagnostics and treatment options in the pre- and postprocedural phase is emphasized...
  56. ncbi Increased levels of plasma tissue factor pathway inhibitor in patients with glioblastoma and intracerebral metastases
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528 Frankfurt Main, Germany
    Neurol Res 25:335-8. 2003
    ..Further studies are needed to clarify the pathogenic mechanism and the clinical relevance of this phenomenon...
  57. ncbi Effect of endothelin-converting enzyme inhibitors on big endothelin-1 induced contraction in isolated rat basilar artery
    M Zimmermann
    Department of Neurosurgery, Johann Wolfgang Goethe University Frankfurt Main, Germany
    Acta Neurochir (Wien) 144:1213-9. 2002
    ....
  58. ncbi Clinical evaluation of intraparenchymal Spiegelberg pressure sensor
    Josef Michael Lang
    Department of Neurosurgery, Neurocenter, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528 Frankfurt am Main, Germany
    Neurosurgery 52:1455-9; discussion 1459. 2003
    ..The Spiegelberg 3-PN intraparenchymal pressure sensor was clinically evaluated...
  59. ncbi Functional impairment, disability, and quality of life outcome after decompressive hemicraniectomy in malignant middle cerebral artery infarction
    Christian Foerch
    Department of Neurology and Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 101:248-54. 2004
    ..The authors sought to determine functional impairment, disability, and health-related quality of life (QOL) outcome in long-term survivors who had undergone this procedure, and tried to identify factors related to functional outcome...
  60. doi Efficacy of silver-bearing external ventricular drainage catheters: a retrospective analysis
    Jens Fichtner
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 112:840-6. 2010
    ..The aim of this analysis was to compare the efficacy of silver-bearing EVD catheters for reducing the incidence of infection with standard nonimpregnated EVD catheters in neurosurgical patients with acute hydrocephalus...
  61. ncbi Single-center experience with TruFill platinum coils for the embolization of cerebral aneurysms
    Bernard Yan
    Institute of Neuroradiology, JWGU, Frankfurt am Main, Germany
    Neuroradiology 48:264-8. 2006
    ..Embolization by TruFill platinum coils has a comparable total aneurysmal occlusion rate to that with GDC. The mid-term reintervention rate is low, and will require verification by future long-term studies...
  62. ncbi Robot-assisted navigated neuroendoscopy
    Michael Zimmermann
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt, Germany
    Neurosurgery 51:1446-51; discussion 1451-2. 2002
    ..With traditional neuroendoscopic techniques (e.g., freehand endoscopy or the use of mechanical arms), definitive controlled movement of the endoscope within the brain depends on the experience and skill of the individual neurosurgeon...
  63. doi Pineal parenchymal tumor of intermediate differentiation: diagnostic pitfalls and discussion of treatment options of a rare tumor entity
    Christian Senft
    Department of Neurosurgery ZNN, Johann Wolfgang Goethe University Clinics, Schleusenweg 2 16, 60528 Frankfurt, Germany
    Neurosurg Rev 31:231-6. 2008
    ..Thus, treatment options including surgery, radiation therapy, and chemotherapy remain controversial. We recommend surgical removal of PPTID, preferably in toto whenever the size of the tumor permits that kind of excision...
  64. ncbi Elastin polymorphism haplotype and intracranial aneurysms are not associated in Central Europe
    Anne Hofer
    Department of Neurology, Johann Wolfgang Goethe University Frankfurt am Main, Germany
    Stroke 34:1207-11. 2003
    ..Recent genomic studies in Japan have defined 3 chromosomal loci and 1 haplotype of elastin polymorphisms as important risk factors, both for affected sib pairs and sporadic patients...
  65. doi A rare anomaly of the anterior communicating artery complex hidden by a large broad-neck aneurysm and disclosed by three-dimensional rotational angiography
    Jean G de Oliveira
    Neurocenter, Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 150:279-84; discussion 284. 2008
    ..The DSA images missed the double fenestration which was disclosed by 3D-RA, indicating the importance of 3D-RA in the diagnosis and surgical planning of intracranial aneurysms...
  66. ncbi Conservative (labyrinth-preserving) transpetrosal approach to the clivus and petroclival region--indications, complications, results and lessons learned
    V Seifert
    Department of Neurosurgery, Johann Wolfgang Goethe University Frankfurt, Schleusenweg 2 16, 60528 Frankfurt am Main, Germany
    Acta Neurochir (Wien) 145:631-42; discussion 642. 2003
    ....
  67. pmc Tissue at risk concept for endovascular treatment of severe vasospasm after aneurysmal subarachnoid haemorrhage
    J Beck
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurol Neurosurg Psychiatry 75:1779-81. 2004
    ....
  68. ncbi Inhibition of endothelin-converting enzyme activity in the rabbit basilar artery
    M Zimmermann
    Neurosurgical Clinic, Johann Wolfgang Goethe University, Frankfurt, Germany
    Neurosurgery 48:902-8; discussion 908-10. 2001
    ..Blocking ET-converting enzyme activity may be a promising approach to the prevention of cerebral vasospasm after subarachnoid hemorrhage...
  69. ncbi The risk of haemorrhage associated with early postoperative heparin administration after intracranial surgery
    A Raabe
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 143:1-7. 2001
    ....
  70. ncbi Robot-assisted navigated endoscopic ventriculostomy: implementation of a new technology and first clinical results
    M Zimmermann
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 146:697-704. 2004
    ..Therefore, the development of robotic systems to assist surgeons in performing complex neurosurgical procedures is a growing field of interest...
  71. ncbi Transcranial and direct cortical stimulation for motor evoked potential monitoring in intracerebral aneurysm surgery
    A Szelenyi
    Department of Neurosurgery, ZNN, Klinikum der Johann Wolfgang Goethe Universitat, Haus 95, Am Schleusenweg 2 16, 60528 Frankfurt Main, Germany
    Neurophysiol Clin 37:391-8. 2007
    ....
  72. ncbi Active secretion of S100B from astrocytes during metabolic stress
    R Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Schleusenweg 2 16, D 60528 Frankfurt, Germany
    Neuroscience 141:1697-701. 2006
    ..Our data suggest that secretion of S100B during the glial response to metabolic injury is an early and active process...
  73. doi Decompressive hemicraniectomy in subarachnoid haemorrhage: the influence of infarction, haemorrhage and brain swelling
    E Güresir
    Department of Neurosurgery, Johann Wolfgang Goethe University Frankfurt am Main, Schleusenweg 2 16, Frankfurt am Main 60528, Germany
    J Neurol Neurosurg Psychiatry 80:799-801. 2009
    ..To analyse decompressive hemicraniectomy (DHC) in patients with aneurysmal subarachnoid haemorrhage (SAH) with regard to infarction, haemorrhage or brain swelling...
  74. ncbi Application of recombinant activated factor VII during surgery for a giant skull base hemangiopericytoma to achieve safe hemostasis. Case report
    Rüdiger Gerlach
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 96:946-8. 2002
    ....
  75. ncbi Cerebrovascular characterization of the novel nonpeptide endothelin-A receptor antagonist LU 208075
    Hartmut Vatter
    Department of Neurosurgery, Johann Wolfgang Goethe University, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
    Clin Neuropharmacol 26:73-83. 2003
    ..The selectivity for the ET(A) receptor was approximately sevenfold. Furthermore, the results may suggest an inhibition of the functional ET-converting enzyme activity by LU 208075...
  76. ncbi Management-related morbidity and mortality in unselected aneurysms of the basilar trunk and vertebrobasilar junction
    V Seifert
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany
    Acta Neurochir (Wien) 143:343-8; discussion 348-9. 2001
    ..CONCLUSIONS: Location, aneurysm size and the severity of SAH may help to predict the subgroup which highly benefits from surgical clipping of these rare vascular lesions...
  77. pmc Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute stroke
    C Foerch
    Department of Neurology, Johann Wolfgang Goethe University Frankfurt am Main, Schleusenweg 2 16, D 60528 Frankfurt am Main, Germany
    J Neurol Neurosurg Psychiatry 77:181-4. 2006
    ..Biomarkers of stroke are an evolving field of clinical research. A serum marker which can differentiate between haemorrhagic and ischaemic stroke in the very early phase would help to optimise acute stroke management...
  78. ncbi Serum markers of brain damage and outcome prediction in patients after severe head injury
    A Raabe
    Department of Neurosurgery, University of Leipzig, Germany
    Br J Neurosurg 13:56-9. 1999
    ..According to our experience, S-100B protein represents the most promising serum marker of brain cell damage currently under investigation...
  79. ncbi Migraine associated bilateral intracerebral haemorrhages
    A Raabe
    Department of Neurosurgery, University of Leipzig, Germany
    Clin Neurol Neurosurg 101:193-5. 1999
    ..The terminology of the syndrome of migraine associated with intracerebral haemorrhage is reviewed...
  80. ncbi Fatal secondary increase in serum S-100B protein after severe head injury. Report of three cases
    A Raabe
    Department of Neurosurgery, Neurology and Neurosurgery Center, University of Frankfurt am Main, Germany
    J Neurosurg 91:875-7. 1999
    ..All three patients died within 72 hours after the excessive increase in S-100B. These findings indicate that major secondary brain damage may occur at a cellular level without being identified by current neuromonitoring techniques...
  81. ncbi Severe delayed diffuse cerebral vasospasm and cerebral infarctions following spinal subdural hemorrhage
    M Setzer
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 146:517-20. 2004
    ..We report a rare case of severe delayed cerebral vasospasm with cerebral infarctions after spinal subdural hemorrhage...
  82. ncbi Difference in configuration of ruptured and unruptured intracranial aneurysms determined by biplanar digital subtraction angiography
    J Beck
    Department of Neurosurgery, Neurology and Neurosurgery Centre, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 145:861-5; discussion 865. 2003
    ..An irregular multilobar appearance was significantly more common in aneurysms of 5-9 mm size that ruptured...
  83. pmc Diffusion tensor tracking of fornix infarction
    Elke Hattingen
    J Neurol Neurosurg Psychiatry 78:655-6. 2007
  84. doi Fluorescence angiography
    Andreas Raabe
    J Neurosurg 108:429-30; author reply 430. 2008
  85. ncbi Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized, double-blind, placebo-controlled, multicenter phase IIa study
    Peter Vajkoczy
    Department of Neurosurgery, University Hospital Mannheim, and Faculty for Clinical Medicine, Karl Ruprecht University of Heidelberg, Mannheim, Switzerland
    J Neurosurg 103:9-17. 2005
    ....
  86. ncbi Perfusion-weighted magnetic resonance imaging in patients with vasospasm: a useful new tool in the management of patients with subarachnoid hemorrhage
    Jürgen Beck
    Neurosurgery 58:E590; author reply E590. 2006
  87. ncbi GFAP versus S100B in serum after traumatic brain injury: relationship to brain damage and outcome
    Linda E Pelinka
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Research Unit of the Austrian Workers Compensation Board AUVA, Vienna, Austria
    J Neurotrauma 21:1553-61. 2004
    ..0005). Both measurement of GFAP and S100B is a useful non-invasive means of identifying brain damage with some differences based on the pattern of TBI and accompanying multiple trauma and/or shock...
  88. doi Radiation exposure during pregnancy
    Andreas Raabe
    Neurosurg Rev 31:351-2; author reply 353-4. 2008
  89. ncbi Hypervolemia in cerebral vasospasm
    Andreas Raabe
    J Neurosurg 104:994-5; author reply 995. 2006
  90. ncbi Glial fibrillary acidic protein in serum after traumatic brain injury and multiple trauma
    Linda E Pelinka
    Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Research Unit of the Austrian Worker s Compensation Board, Vienna, Austria
    J Trauma 57:1006-12. 2004
    ....
  91. ncbi Fourier analysis of intracranial aneurysms: towards an objective and quantitative evaluation of the shape of aneurysms
    Stefan Rohde
    Institut für Neuroradiologie, Klinikum der Johann Wolfgang Goethe Universitat, Schleusenweg 2 16, 60528 Frankfurt am Main, Germany
    Neuroradiology 47:121-6. 2005
    ..05). Our data have shown significant differences in shape between RIA and UIA, and further developments of Fourier analysis may provide an objective factor for the assessment of the risk of rupture...
  92. doi Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebo-controlled phase 2 dose-finding trial
    R Loch MacDonald
    St Michael s Hospital, Division of Neurosurgery, Toronto, Ontario, Canada
    Stroke 39:3015-21. 2008
    ....
  93. ncbi Impairment of cerebral perfusion and infarct patterns attributable to vasospasm after aneurysmal subarachnoid hemorrhage: a prospective MRI and DSA study
    Stefan Weidauer
    Institute of Neuroradiology, University of Frankfurt, Frankfurt, Germany
    Stroke 38:1831-6. 2007
    ..The objective of this study was to investigate disturbance of perfusion and infarct patterns attributable to cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH)...
  94. ncbi Adaptive noninvasive assessment of intracranial pressure and cerebral autoregulation
    Bernhard Schmidt
    Department of Neurology, Medical Centre Chemnitz, Chemnitz, Germany
    Stroke 34:84-9. 2003
    ..This modification was intended to improve the quality of nICP estimation and noninvasive assessment of pressure reactivity of the cerebrovascular system...
  95. ncbi Symmetry of cerebral hemodynamic indices derived from bilateral transcranial Doppler
    Eric A Schmidt
    Academic Neurosurgery Unit, PO Box 167, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, United Kingdom
    J Neuroimaging 13:248-54. 2003
    ..The authors evaluated with bilateral transcranial Doppler (TCD) ultrasonography the norm of interhemispheric difference for several cerebrovascular hemodynamic parameters...