A Pape

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. pmc The choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs
    Andreas Pape
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Management, JW Goethe University Hospital Frankfurt, Theodor Stern Kai 7, Frankfurt Main, 60590, Germany
    Crit Care 16:R69. 2012
  2. doi request reprint Improved short-term survival with polyethylene glycol modified hemoglobin liposomes in critical normovolemic anemia
    Andreas Pape
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Management, J W Goethe University Hospital, Theodor Stern Kai 7, 60590, Frankfurt Main, Germany
    Intensive Care Med 34:1534-43. 2008
  3. ncbi request reprint Fluid resuscitation from severe hemorrhagic shock using diaspirin cross-linked hemoglobin fails to improve pancreatic and renal perfusion
    A Pape
    Clinic of Anaesthesiology, Intensive Care and Pain Management, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Acta Anaesthesiol Scand 48:1328-37. 2004
  4. ncbi request reprint Alternatives to allogeneic blood transfusions
    Andreas Pape
    Clinic of Anoesthesiology, Intensive Care Medicine and Pain Management, J W Goethe University Hospital Frankfurt am Main, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Best Pract Res Clin Anaesthesiol 21:221-39. 2007
  5. ncbi request reprint Hyperoxic ventilation enables hemodilution beyond the critical myocardial hemoglobin concentration
    J Meier
    Department of Anesthesiology, Intensive Care Medicine and Pain Control, Johann Wolfgang Goethe University, Hospital Center, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Eur J Med Res 10:462-8. 2005
  6. ncbi request reprint Diaspirin cross-linked hemoglobin fails to improve left ventricular diastolic function after fluid resuscitation from hemorrhagic shock
    A Pape
    Clinic of Anaesthesiology, Ludwig Maximilians University, Munich, Germany
    Eur Surg Res 33:318-26. 2001
  7. ncbi request reprint Diaspirin-crosslinked hemoglobin reduces mortality of severe hemorrhagic shock in pigs with critical coronary stenosis
    O Habler
    Clinic of Anesthesiology, Ludwig Maximilians University, Munich, Germany
    Crit Care Med 28:1889-98. 2000
  8. ncbi request reprint Hyperoxic ventilation increases the tolerance of acute normovolemic anemia in anesthetized pigs
    A Pape
    Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Crit Care Med 34:1475-82. 2006
  9. doi request reprint Neuromuscular blockade with rocuronium bromide increases the tolerance of acute normovolemic anemia in anesthetized pigs
    A Pape
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Management, J W Goethe University Hospital, Frankfurt a M, Germany
    Eur Surg Res 48:16-25. 2012
  10. doi request reprint The limit of anemia tolerance during hyperoxic ventilation with pure oxygen in anesthetized domestic pigs
    A Pape
    Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt Main, Germany
    Eur Surg Res 51:156-69. 2013

Detail Information

Publications17

  1. pmc The choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs
    Andreas Pape
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Management, JW Goethe University Hospital Frankfurt, Theodor Stern Kai 7, Frankfurt Main, 60590, Germany
    Crit Care 16:R69. 2012
    ..Whether the choice of the infusion fluid has an impact on the maintenance of oxygen (O₂) supply during acute normovolemic anemia has not been investigated so far...
  2. doi request reprint Improved short-term survival with polyethylene glycol modified hemoglobin liposomes in critical normovolemic anemia
    Andreas Pape
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Management, J W Goethe University Hospital, Theodor Stern Kai 7, 60590, Frankfurt Main, Germany
    Intensive Care Med 34:1534-43. 2008
    ..To investigate the efficacy of a polyethylene glycol (PEG) modified formulation of liposome-encapsulated hemoglobin (LEH) as an oxygen-carrying blood substitute in the treatment of critical normovolemic anemia...
  3. ncbi request reprint Fluid resuscitation from severe hemorrhagic shock using diaspirin cross-linked hemoglobin fails to improve pancreatic and renal perfusion
    A Pape
    Clinic of Anaesthesiology, Intensive Care and Pain Management, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Acta Anaesthesiol Scand 48:1328-37. 2004
    ..Therefore, fluid resuscitation from severe hemorrhagic shock using DCLHb was expected to improve perfusion pressure and tissue perfusion of kidneys and pancreas...
  4. ncbi request reprint Alternatives to allogeneic blood transfusions
    Andreas Pape
    Clinic of Anoesthesiology, Intensive Care Medicine and Pain Management, J W Goethe University Hospital Frankfurt am Main, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Best Pract Res Clin Anaesthesiol 21:221-39. 2007
    ..Nevertheless, to date no artificial oxygen carrier is available for routine clinical use, and further studies are needed to show the safety and efficacy of these substances...
  5. ncbi request reprint Hyperoxic ventilation enables hemodilution beyond the critical myocardial hemoglobin concentration
    J Meier
    Department of Anesthesiology, Intensive Care Medicine and Pain Control, Johann Wolfgang Goethe University, Hospital Center, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Eur J Med Res 10:462-8. 2005
    ..0, HV) reverses hypoxia-induced ECG-changes and enables survival for several hours. The quantification of the HV-induced gain in anemia tolerance and particularly the Hb-equivalent of HV in this situation are unknown...
  6. ncbi request reprint Diaspirin cross-linked hemoglobin fails to improve left ventricular diastolic function after fluid resuscitation from hemorrhagic shock
    A Pape
    Clinic of Anaesthesiology, Ludwig Maximilians University, Munich, Germany
    Eur Surg Res 33:318-26. 2001
    ..However, positive effects on myocardial perfusion and oxygenation result in a significant reduction of the mortality of severe hemorrhagic shock...
  7. ncbi request reprint Diaspirin-crosslinked hemoglobin reduces mortality of severe hemorrhagic shock in pigs with critical coronary stenosis
    O Habler
    Clinic of Anesthesiology, Ludwig Maximilians University, Munich, Germany
    Crit Care Med 28:1889-98. 2000
    ....
  8. ncbi request reprint Hyperoxic ventilation increases the tolerance of acute normovolemic anemia in anesthetized pigs
    A Pape
    Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Crit Care Med 34:1475-82. 2006
    ..To investigate the impact of prophylactic hyperoxic ventilation with Fio2 0.6 on the physiologic limit of acute normovolemic anemia...
  9. doi request reprint Neuromuscular blockade with rocuronium bromide increases the tolerance of acute normovolemic anemia in anesthetized pigs
    A Pape
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Management, J W Goethe University Hospital, Frankfurt a M, Germany
    Eur Surg Res 48:16-25. 2012
    ..The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated...
  10. doi request reprint The limit of anemia tolerance during hyperoxic ventilation with pure oxygen in anesthetized domestic pigs
    A Pape
    Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt Main, Germany
    Eur Surg Res 51:156-69. 2013
    ..While this effect could be demonstrated for HV with inspiratory O2 fraction (FiO2) 0.6, it was unclear whether HV with pure oxygen (FiO2 1.0) would have an additional effect on the physiological limit of acute normovolemic anemia...
  11. ncbi request reprint [Indications for blood transfusion during orthopedic surgery]
    O Habler
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie der Johann Wolfgang Goethe Universität Frankfurt
    Orthopade 33:774-83. 2004
    ....
  12. ncbi request reprint [Artificial oxygen carriers as an alternative to red blood cell transfusion]
    O Habler
    Klinik fur Anasthesiologie, Intensivmedizin und Schmerztherapie, Johann Wolfgang Goethe Universitat, Frankfurt a M
    Anaesthesist 54:741-54. 2005
    ..Although reduction of perioperative allogeneic blood transfusion has already been demonstrated for HBOC and PFC, the global clinical establishment of artificial oxygen carriers is not to be expected in the near future...
  13. ncbi request reprint Norepinephrine increases tolerance to acute anemia
    Jens Meier
    Department of Anesthesiology, Intensive Care Medicine, and Pain Control, J W Goethe University Hospital, Frankfurt, Germany
    Crit Care Med 35:1484-92. 2007
    ..However, it is unknown whether the stabilization of MAP and coronary perfusion pressure with norepinephrine as the sole therapeutic modality may also increase tolerance to extreme anemia and thus improve outcome...
  14. ncbi request reprint Regional blood flow during hyperoxic haemodilution
    Jens Meier
    Department of Anesthesiology, Johann Wolfgang Goethe University, Frankfurt, Germany
    Clin Physiol Funct Imaging 25:158-65. 2005
    ..We therefore investigated the effects of HV on regional blood flow (RBF) and O(2) supply of different vital organs during moderate normovolaemic anaemia...
  15. ncbi request reprint Hyperoxic ventilation reduces six-hour mortality after partial fluid resuscitation from hemorrhagic shock
    Jens Meier
    Department of Anesthesiology, Intensive Care Medicine, and Pain Control, J W Goethe University Hospital, Frankfurt, Germany
    Shock 22:240-7. 2004
    ..e., 6-h mortality 0%; G 0.21 versus G 1.0 P < 0.05). In anesthetized pigs submitted to lethal hemorrhagic shock, the supplementation of partial fluid resuscitation with HV improved tissue oxygenation and enabled survival for 6 h...
  16. ncbi request reprint Effects of standardized acute normovolemic hemodilution on intraoperative allogeneic blood transfusion in patients undergoing major maxillofacial surgery
    O Habler
    Clinic of Anesthesiology, Johann Wolfgang Goethe University Frankfurt, Frankfurt, Germany
    Int J Oral Maxillofac Surg 33:467-75. 2004
    ....
  17. ncbi request reprint Hyperoxia in lethal methemoglobinemia: effects on oxygen transport, tissue oxygenation, and survival in pigs
    Jens Meier
    Department of Anesthesiology, Intensive Care Medicine, and Pain Control, Johann Wolfgang Goethe University Frankfurt am Main, Frankfurt, Germany
    Crit Care Med 33:1582-8. 2005
    ..The objective was to assess whether using hyperoxic ventilation as the sole therapeutic intervention (i.e., ventilation with pure oxygen, Fio2 1.0) improves the short-term (6-hr) survival rate during otherwise lethal methemoglobinemia...