Research Topics
| K MaurerSummaryAffiliation: Frankfurt am Main Country: Germany Publications
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Detail Information
Publications
Paintings of an artist with Alzheimer's disease: visuoconstructural deficits during dementiaK Maurer
Department of Psychiatry and Psychotherapy, University Clinic of Frankfurt, Germany
J Neural Transm 111:235-45. 2004..Carolus Horn's artwork lets us see the world through the patient's eyes and by that it helps us to better understand the consequences of visuospatial and cognitive changes in AD...
Historical background of Alzheimer's research done 100 years agoK Maurer
Department of Psychiatry and Psychotherapy, University of Frankfurt, Frankfurt, Germany
J Neural Transm 113:1597-601. 2006
Apoptosis of CD4+ T and natural killer cells in Alzheimer's diseaseK Schindowski
Institute of Pharmacology, Biocenter, Johann Wolfgang Goethe University, Frankfurt, Germany
Pharmacopsychiatry 39:220-8. 2006..Immunotherapy appears to be a potent treatment against Alzheimer's disease (AD), but the mechanisms underlying neural-immune interaction are still not known...
Multimodal imaging of residual function and compensatory resource allocation in cortical atrophy: a case study of parietal lobe function in a patient with Huntington's diseaseT Dierks
Department of Psychiatry and Psychotherapy I, University of Frankfurt Main, Frankfurt, Germany
Psychiatry Res 90:67-75. 1999..We propose that fMRI should be considered as a tool for the assessment of functionality of morphologically abnormal cortex and for the investigation of compensatory resource allocation in neurodegenerative disorders...
[Dementia and suicide]B Schneider
Zentrum der Psychiatrie, Klinik für Psychiatrie und Psychotherapie I, Johann Wolfgang Goethe Universitat, Frankfurt Main
Fortschr Neurol Psychiatr 69:164-9. 2001..This review comprehensively presents the association between cognitive deficits, insight in early stages of dementia and suicidality and possible confounders which have not systematically been investigated up to now...
Multimodal imaging of residual function and compensatory resource allocation in cortical atrophy: a case study of parietal lobe function in a patient with Huntington's diseaseT Dierks
Department of Psychiatry and Psychotherapy I, University of Frankfurt Main, Germany
Psychiatry Res 84:27-35. 1998..We propose that fMRI should be considered as a tool for the assessment of functionality of morphologically abnormal cortex and for the investigation of compensatory resource allocation in neurodegenerative disorders...
Generators of brain electrical activity in patients with Wilson's diseaseT Dierks
Dept of Psychiatry I, University of Frankfurt Main, Frankfurt
Eur Arch Psychiatry Clin Neurosci 249:15-20. 1999....
Bias in computerized neuropsychological assessment of depressive disorders caused by computer attitudeB Weber
Department of Psychiatry and Psychotherapy I, J W Goethe University, Frankfurt Main, Germany
Acta Psychiatr Scand 105:126-30. 2002..Psychiatric patients are increasingly confronted to computerized psychological and psychopathological assessment. Patients' attitude to computers was reported to affect acceptance of computerized assessment...
Event-related potentials and psychopharmacology. Cholinergic modulation of P300T Dierks
Department of Psychiatry I, University of Frankfurt, Germany
Pharmacopsychiatry 27:72-4. 1994....
Apolipoprotein E epsilon 4 is associated with an increased vulnerability to cell death in Alzheimer's diseaseC Frey
Department of Pharmacology, Biocenter, University of Frankfurt, Germany
J Neural Transm 113:1753-61. 2006..Therefore, it is likely that circulating A beta is not responsible for the observed effects, which might rather reflect an ongoing systemic response in AD, e.g. an increase in CD95 expression...
Alois Alzheimer revisited: differences in origin of the disease carrying his nameK Maurer
Clinic for Psychiatry, University of Frankfurt, Frankfurt/Main, Germany
J Neural Transm 113:1645-58. 2006..Alois Alzheimer may have been so prescient to assume most of this 100 years ago...
Intensity dependence of auditory evoked potentials (AEPs) as biological marker for cerebral serotonin levels: effects of tryptophan depletion in healthy subjectsT Dierks
Division of Clinical Neurophysiology, University of Frankfurt, Frankfurt, Germany
Psychopharmacology (Berl) 146:101-7. 1999..The intensity dependence of the auditory evoked potentials (AEP) has been suggested to be a specific biological marker of central serotonergic activity...
Functional imaging of visuospatial processing in Alzheimer's diseaseD Prvulovic
Department of Psychiatry, University of Frankfurt, Frankfurt, Germany
Neuroimage 17:1403-14. 2002..We furthermore suggest that local cerebral atrophy should be considered as a covariate in functional imaging studies of neurodegenerative disorders...
Subclinical hyperthyroidism in dementia and correlation of the metabolic index in FDG-PETN Döbert
Department of Nuclear Medicine, University of Frankfurt, Frankfurt, Germany
Acta Med Austriaca 30:130-3. 2003..Thyroid hormone status and thyroid antibodies were evaluated in patients suffering from dementia for further study of an association of hyperthyroidism with AD and vascular dementia (VD), respectively...
Acute effects of treatment for prodromal symptoms for people putatively in a late initial prodromal state of psychosisS Ruhrmann
Department of Psychiatry and Psychotherapy, University Hospital of the University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
Br J Psychiatry Suppl 51:s88-95. 2007..People in a putatively late prodromal state not only have an enhanced risk for psychosis but already suffer from mental and functional disturbances...
Changes in negative symptoms and EEG in schizophrenic patients after repetitive transcranial magnetic stimulation (rTMS): an open-label pilot studyM Jandl
Division of Neurophysiology and Neuroimaging, Department of Psychiatry and Psychotherapy I, Johann Wolfgang Goethe University, Frankfurt, Germany
J Neural Transm 112:955-67. 2005..Although we are aware of the limitations of this study, we assume a slight improvement in NS. The EEG findings refer to a possible neurophysiologic correlate of their improvement after rTMS...
Elevated cytokine expression in the orbitofrontal cortex of victims of suicideL H Tonelli
Mood and Anxiety Program, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Acta Psychiatr Scand 117:198-206. 2008....
First onset and early symptomatology of schizophrenia. A chapter of epidemiological and neurobiological research into age and sex differencesH Hafner
Central Institute of Mental Health, W Mannheim, Federal Republic of Germany
Eur Arch Psychiatry Clin Neurosci 242:109-18. 1992..Apparently, estrogens raise the vulnerability threshold until menopause and have a slight neuroleptic-like effect on the symptomatology in acute schizophrenic episodes...
Enhanced ROS-generation in lymphocytes from Alzheimer's patientsS Leutner
Department of Pharmacology, Biocenter, J. W. Goethe University of Frankfurt, Marie-Curie-Str. 9, 60439 Frankfurt am Main, Germany
Pharmacopsychiatry 38:312-5. 2005..DISCUSSION: The data suggest that the defect(s) responsible for enhanced ROS production in AD may involve different or additional biological pathways than those involved in enhanced ROS generation during aging...
[Effect of daily living-related cognitive training on attention and memory performance of persons with dementia]T Bernhardt
, 60528 Frankfurt, Germany
Z Gerontol Geriatr 35:32-8. 2002..We can show significant improvements of attention and memory performance in our experimental group in comparison to the control group...
The experimental combination of rTMS and fMRI reveals the functional relevance of parietal cortex for visuospatial functionsA T Sack
Department of Psychiatry, Division of Neurophysiology and Neuroimaging, , Theodor-Stern-Kai 7, DE-60590 Frankfurt, Germany
Brain Res Cogn Brain Res 13:85-93. 2002....
A comparison of qEEG and HMPAO-SPECT in relation to the clinical severity of Alzheimer's diseaseT J Müller
Department of Psychiatry, University Hospital Wurzburg, Germany
Eur Arch Psychiatry Clin Neurosci 247:259-63. 1997..Whereas SPECT is a well-established tool for the diagnosis of dementia, the present study indicates qEEG as a potential marker for the staging of the cognitive decline in DAT...
When and how does schizophrenia produce social deficits?H Hafner
Schizophrenia Research Unit, Central Institute of Mental Health, Mannheim, Germany
Eur Arch Psychiatry Clin Neurosci 246:17-28. 1995..The unfavourable early course in men was due mainly to their significantly lower age at onset. These results raise questions concerning an earlier therapeutic and rehabilitative intervention...
Integrity of the blood-CSF barrier in dementia of Alzheimer type: CSF/serum ratios of albumin and IgGL Frolich
Department of Psychiatry, University of Wurzburg, Federal Republic of Germany
Eur Arch Psychiatry Clin Neurosci 240:363-6. 1991..The data do not support the hypothesis that a pathological leakage through the blood-CSF barrier facilitates the entry of extraneuronal proteins to the CNS, which might contribute to the pathophysiological process in DAT...
Safety and efficacy of galantamine in subjects with mild cognitive impairmentB Winblad
Karolinska Institutet, Alzheimer s Disease Research Center, Division of Geriatric Medicine, Stockholm, Sweden
Neurology 70:2024-35. 2008....
