Albrecht Ludwig

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. ncbi Release of latent ClyA cytolysin from Escherichia coli mediated by a bacteriophage-associated putative holin (BlyA) from Borrelia burgdorferi
    Albrecht Ludwig
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universität Frankfurt am Main, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    Int J Med Microbiol 298:473-81. 2008
  2. pmc Mutations affecting export and activity of cytolysin A from Escherichia coli
    Albrecht Ludwig
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Bacteriol 192:4001-11. 2010
  3. pmc Molecular analysis of cytolysin A (ClyA) in pathogenic Escherichia coli strains
    Albrecht Ludwig
    Institut fur Medizinische Mikrobiologie, Klinikum der Johann Wolfgang Goethe Universitat, 60596 Frankfurt am Main, Germany
    J Bacteriol 186:5311-20. 2004
  4. doi ClyA cytolysin from Salmonella: distribution within the genus, regulation of expression by SlyA, and pore-forming characteristics
    Christine von Rhein
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    Int J Med Microbiol 299:21-35. 2009
  5. pmc Compensatory adaptation to the loss of biological fitness associated with acquisition of fusidic acid resistance in Staphylococcus aureus
    Silke Besier
    Institut fur Medizinische Mikrobiologie, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Strasse 40, 60596 Frankfurt am Main, Germany
    Antimicrob Agents Chemother 49:1426-31. 2005
  6. pmc Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances
    Silke Besier
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    Antimicrob Agents Chemother 52:1570-2. 2008
  7. doi Occurrence and characteristics of the cytolysin A gene in Shigella strains and other members of the family Enterobacteriaceae
    Christine von Rhein
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Strasse 40, Frankfurt am Main, Germany
    FEMS Microbiol Lett 287:143-8. 2008
  8. ncbi Molecular analysis of the thymidine-auxotrophic small colony variant phenotype of Staphylococcus aureus
    Silke Besier
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Strasse 40, D 60596 Frankfurt am Main, Germany
    Int J Med Microbiol 297:217-25. 2007
  9. pmc Biological cost of rifampin resistance from the perspective of Staphylococcus aureus
    Thomas A Wichelhaus
    Institut fur Medizinische Mikrobiologie, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    Antimicrob Agents Chemother 46:3381-5. 2002
  10. pmc Serologic evidence for effective production of cytolysin A in Salmonella enterica serovars typhi and paratyphi A during human infection
    Christine von Rhein
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universität Frankfurt am Main, Paul Ehrlich Str 40, 60596 Frankfurt am Main, Germany
    Infect Immun 74:6505-8. 2006

Collaborators

Detail Information

Publications12

  1. ncbi Release of latent ClyA cytolysin from Escherichia coli mediated by a bacteriophage-associated putative holin (BlyA) from Borrelia burgdorferi
    Albrecht Ludwig
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universität Frankfurt am Main, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    Int J Med Microbiol 298:473-81. 2008
    ..These findings are compatible with the presumption that BlyA functions as a membrane-active holin...
  2. pmc Mutations affecting export and activity of cytolysin A from Escherichia coli
    Albrecht Ludwig
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Bacteriol 192:4001-11. 2010
    ..The latter regions thus apparently promote membrane interaction without being directly required for pore formation in a lipid bilayer...
  3. pmc Molecular analysis of cytolysin A (ClyA) in pathogenic Escherichia coli strains
    Albrecht Ludwig
    Institut fur Medizinische Mikrobiologie, Klinikum der Johann Wolfgang Goethe Universitat, 60596 Frankfurt am Main, Germany
    J Bacteriol 186:5311-20. 2004
    ..The presented data indicate that cytolysin A can play a role only for some of the pathogenic E. coli strains...
  4. doi ClyA cytolysin from Salmonella: distribution within the genus, regulation of expression by SlyA, and pore-forming characteristics
    Christine von Rhein
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    Int J Med Microbiol 299:21-35. 2009
    ..Typhi and S. Paratyphi A strains produce substantial amounts of ClyA during human infection, these data suggest that ClyA may play a role in S. Typhi and S. Paratyphi A pathogenesis...
  5. pmc Compensatory adaptation to the loss of biological fitness associated with acquisition of fusidic acid resistance in Staphylococcus aureus
    Silke Besier
    Institut fur Medizinische Mikrobiologie, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Strasse 40, 60596 Frankfurt am Main, Germany
    Antimicrob Agents Chemother 49:1426-31. 2005
    ..aureus can be reduced considerably by specific compensating mutations in this target protein. This compensatory adaptation most likely plays a significant role in the stabilization of resistant bacteria within a given population...
  6. pmc Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances
    Silke Besier
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    Antimicrob Agents Chemother 52:1570-2. 2008
    ....
  7. doi Occurrence and characteristics of the cytolysin A gene in Shigella strains and other members of the family Enterobacteriaceae
    Christine von Rhein
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Strasse 40, Frankfurt am Main, Germany
    FEMS Microbiol Lett 287:143-8. 2008
    ..According to these data, ClyA may play a role only for a rather small subset of the enteric bacteria...
  8. ncbi Molecular analysis of the thymidine-auxotrophic small colony variant phenotype of Staphylococcus aureus
    Silke Besier
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Strasse 40, D 60596 Frankfurt am Main, Germany
    Int J Med Microbiol 297:217-25. 2007
    ..In conclusion, these data confirm at the molecular level that impaired thymidylate synthase function is causative for the formation of the thymidine-auxotrophic SCV phenotype in S. aureus...
  9. pmc Biological cost of rifampin resistance from the perspective of Staphylococcus aureus
    Thomas A Wichelhaus
    Institut fur Medizinische Mikrobiologie, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main, Germany
    Antimicrob Agents Chemother 46:3381-5. 2002
    ..The restriction to distinct mutations that confer rifampin resistance in vivo, as demonstrated here, appears to be determined by the Darwinian fitness of the organisms...
  10. pmc Serologic evidence for effective production of cytolysin A in Salmonella enterica serovars typhi and paratyphi A during human infection
    Christine von Rhein
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe Universität Frankfurt am Main, Paul Ehrlich Str 40, 60596 Frankfurt am Main, Germany
    Infect Immun 74:6505-8. 2006
    ..We show here that human infections by these pathogens cause a specific antibody response to ClyA, indicating effective toxin production during infection...
  11. ncbi Molecular analysis of fusidic acid resistance in Staphylococcus aureus
    Silke Besier
    Institut fur Medizinische Mikrobiologie, Klinikum der J W Goethe Universitat, Paul Ehrlich Str 40, 60596 Frankfurt am Main, Germany
    Mol Microbiol 47:463-9. 2003
    ..Thus, the data presented provide evidence for the crucial importance of individual amino acid exchanges within EF-G for the generation of fusidic acid resistance in S. aureus...
  12. pmc Differential regulation of multiple proteins of Escherichia coli and Salmonella enterica serovar Typhimurium by the transcriptional regulator SlyA
    Andrea Spory
    Lehrstuhl fur Mikrobiologie, Theodor Boveri Institut für Biowissenschaften Biozentrum, Universitat Wurzburg, 97074 Wurzburg, Germany
    J Bacteriol 184:3549-59. 2002
    ..The data suggest that gene regulation by SlyA might be crucial for intracellular survival and/or replication of both EIEC and Salmonella serovar Typhimurium in phagocytic host cells...