M W Lorenz

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. doi request reprint Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data
    Matthias W Lorenz
    Department of Neurology, University Hospital, J W Goethe University, Frankfurt am Main, Germany
    Lancet 379:2053-62. 2012
  2. ncbi request reprint Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS)
    Matthias W Lorenz
    Department of Neurology, Johann Wofgang Goethe University, Frankfurt am Main, Germany
    Stroke 37:87-92. 2006
  3. ncbi request reprint [Evaluation of different protocols for the leg cuff technique for measurement of dynamic cerebral autoregulation]
    M Lorenz
    Neurologische Klinik der Johann Wolfgang Goethe Universität, Frankfurt am Main
    Ultraschall Med 27:368-73. 2006
  4. ncbi request reprint Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis
    Matthias W Lorenz
    Johann Wolfgang Goethe University, Department for Neurology, Schleusenweg 2 16, D 60528 Frankfurt Main, Germany
    Circulation 115:459-67. 2007
  5. ncbi request reprint Both long-term HIV infection and highly active antiretroviral therapy are independent risk factors for early carotid atherosclerosis
    M W Lorenz
    Johann Wolfgang Goethe University Hospital, Department of Neurology, Frankfurt am Main, Germany
    Atherosclerosis 196:720-6. 2008
  6. ncbi request reprint High-sensitivity C-reactive protein is not associated with carotid intima-media progression: the carotid atherosclerosis progression study
    Matthias W Lorenz
    Department of Neurology, J W Goethe University, Frankfurt am Main, Germany
    Stroke 38:1774-9. 2007
  7. pmc Anthropometric approximation of body weight in unresponsive stroke patients
    M W Lorenz
    Johann Wolfgang Goethe University, Department for Neurology, Schleusenweg 2 16, D 60528 Frankfurt Main, Germany
    J Neurol Neurosurg Psychiatry 78:1331-6. 2007
  8. ncbi request reprint Influence of temporal insonation window quality on the assessment of cerebral autoregulation with transcranial Doppler sonography
    Matthias W Lorenz
    Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Ultrasound Med Biol 33:1540-5. 2007
  9. ncbi request reprint Assessment of cerebral autoregulation with transcranial Doppler sonography in poor bone windows using constant infusion of an ultrasound contrast agent
    Matthias W Lorenz
    Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Ultrasound Med Biol 34:345-53. 2008
  10. doi request reprint Effects of poor bone window on the assessment of cerebral autoregulation with transcranial Doppler sonography - a source of systematic bias and strategies to avoid it
    Matthias W Lorenz
    Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurol Sci 283:49-56. 2009

Detail Information

Publications30

  1. doi request reprint Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data
    Matthias W Lorenz
    Department of Neurology, University Hospital, J W Goethe University, Frankfurt am Main, Germany
    Lancet 379:2053-62. 2012
    ..An association between changes in cIMT and cardiovascular risk is frequently assumed but has rarely been reported. Our aim was to test this association...
  2. ncbi request reprint Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS)
    Matthias W Lorenz
    Department of Neurology, Johann Wofgang Goethe University, Frankfurt am Main, Germany
    Stroke 37:87-92. 2006
    ..Carotid intima-media thickness (IMT) is an independent predictor of vascular events in age groups >45 years. However, there is little information about the predictive value of IMT in younger individuals...
  3. ncbi request reprint [Evaluation of different protocols for the leg cuff technique for measurement of dynamic cerebral autoregulation]
    M Lorenz
    Neurologische Klinik der Johann Wolfgang Goethe Universität, Frankfurt am Main
    Ultraschall Med 27:368-73. 2006
    ..In the literature different protocols to choose cuff pressure have been described. The aim of this study is to find a technique as accurate as possible without un-necessary inconvenience for the patient...
  4. ncbi request reprint Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis
    Matthias W Lorenz
    Johann Wolfgang Goethe University, Department for Neurology, Schleusenweg 2 16, D 60528 Frankfurt Main, Germany
    Circulation 115:459-67. 2007
    ..Its use relies on its ability to predict future clinical cardiovascular end points. We performed a systematic review and meta-analysis of data to examine this association...
  5. ncbi request reprint Both long-term HIV infection and highly active antiretroviral therapy are independent risk factors for early carotid atherosclerosis
    M W Lorenz
    Johann Wolfgang Goethe University Hospital, Department of Neurology, Frankfurt am Main, Germany
    Atherosclerosis 196:720-6. 2008
    ..We investigated the relationship between HIV infection, antiretroviral medication and ultrasound evidence of early atherosclerosis in the context of vascular risk factors...
  6. ncbi request reprint High-sensitivity C-reactive protein is not associated with carotid intima-media progression: the carotid atherosclerosis progression study
    Matthias W Lorenz
    Department of Neurology, J W Goethe University, Frankfurt am Main, Germany
    Stroke 38:1774-9. 2007
    ..It is unclear whether elevated serum C-reactive protein (CRP) is causal to the initiation and progression of atherosclerosis. We undertook a prospective longitudinal cohort study to address this question...
  7. pmc Anthropometric approximation of body weight in unresponsive stroke patients
    M W Lorenz
    Johann Wolfgang Goethe University, Department for Neurology, Schleusenweg 2 16, D 60528 Frankfurt Main, Germany
    J Neurol Neurosurg Psychiatry 78:1331-6. 2007
    ..Instead, weight is estimated visually by the attending physician, but this is known to be inaccurate...
  8. ncbi request reprint Influence of temporal insonation window quality on the assessment of cerebral autoregulation with transcranial Doppler sonography
    Matthias W Lorenz
    Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Ultrasound Med Biol 33:1540-5. 2007
    ..This must be considered when studies of elderly patients are planned. This article discusses strategies to account for this bias...
  9. ncbi request reprint Assessment of cerebral autoregulation with transcranial Doppler sonography in poor bone windows using constant infusion of an ultrasound contrast agent
    Matthias W Lorenz
    Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Ultrasound Med Biol 34:345-53. 2008
    ..Furthermore, infusion of the contrast agent can improve reproducibility and contribute to the credibility of autoregulation assessment in the elderly. (E-mail: matthias.lorenz@em.uni-frankfurt.de)...
  10. doi request reprint Effects of poor bone window on the assessment of cerebral autoregulation with transcranial Doppler sonography - a source of systematic bias and strategies to avoid it
    Matthias W Lorenz
    Department of Neurology, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurol Sci 283:49-56. 2009
    ..The consequences of poor insonation conditions on autoregulation parameters assessed with transcranial Doppler (TCD) are unclear...
  11. pmc Individual progression of carotid intima media thickness as a surrogate for vascular risk (PROG-IMT): Rationale and design of a meta-analysis project
    Matthias W Lorenz
    Department of Neurology, University Hospital, Goethe University, Frankfurt am Main, Germany
    Am Heart J 159:730-736.e2. 2010
    ..Recruitment strategies, inclusion criteria, and estimates of the expected numbers of eligible studies are presented along with a detailed analysis plan...
  12. doi request reprint Is carotid intima media thickness useful for individual prediction of cardiovascular risk? Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS)
    Matthias W Lorenz
    Department of Neurology, Johann Wolfgang Goethe University, Schleusenweg 2 16, Frankfurt am Main D 60528, Germany
    Eur Heart J 31:2041-8. 2010
    ..It is often suggested that cIMT be used as a screening tool to select subjects with an elevated event risk. Whether cIMT adds information to traditional risk models has so far received little investigation...
  13. pmc Risk of symptomatic intracerebral hemorrhage in patients treated with intra-arterial thrombolysis
    O C Singer
    Klinik fur Neurologie, Goethe Universitat, Frankfurt, Germany
    Cerebrovasc Dis 27:368-74. 2009
    ..In the present study, we investigated the rate of sICH in IA and combined IV + IA thrombolysis versus IV thrombolysis after adjusting for differences in clinical and MRI parameters...
  14. ncbi request reprint Isolated hypoxic perfusion with mitomycin C in patients with advanced pancreatic cancer
    M Lorenz
    Department of General and Vascular Surgery, University of Frankfurt Medical Center, Frankfurt am Main, Germany
    Eur J Surg Oncol 24:542-7. 1998
    ..An established, commercially available system of isolated hypoxic perfusion (IHP) was therefore evaluated in patients with unresectable or recurrent pancreatic cancer...
  15. ncbi request reprint [Colorectal carcinoma--surgical interventions in metastases]
    M Lorenz
    Klinik für Allgemein und Gefässchirurgie Klinikum der Johann Wolfgang Goethe Universität Theodor Stern Kai 7 D 60590 Frankfurt
    Praxis (Bern 1994) 91:1485-95. 2002
    ..Due to the complex disease and the necessary technical knowledge the treatment outcome is better in the cooperation of colorectal specialists from surgery, gastroenterology and medical and radiation oncology...
  16. ncbi request reprint Impact of dopamine and endothelin-1 antagonism on portal venous blood flow during laparoscopic surgery
    Z G Kim
    Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt Main, Germany
    Surg Endosc 16:1292-6. 2002
    ..Whether dopamine and endothelin-1 (ET-1) antagonists might restore liver blood during laparoscopic surgery has not yet been investigated...
  17. ncbi request reprint Regional chemotherapy in the treatment of advanced pancreatic cancer--is it relevant?
    M Lorenz
    Department of General and Vascular Surgery, University Hospital of Frankfurt, Johann Wolfgang Goethe University, Germany
    Eur J Cancer 36:957-65. 2000
    ..For these reasons, none of the reported treatment regimens can be considered to be standard treatment and in order to evaluate, if regional chemotherapy is indeed superior to systemic chemotherapy, randomised trials must be conducted...
  18. ncbi request reprint Randomized, multicenter trial of fluorouracil plus leucovorin administered either via hepatic arterial or intravenous infusion versus fluorodeoxyuridine administered via hepatic arterial infusion in patients with nonresectable liver metastases from colore
    M Lorenz
    Department of General and Vascular Surgery, Johann Wolfgang Goethe Universit at, Frankfurt am Main, Germany
    J Clin Oncol 18:243-54. 2000
    ....
  19. ncbi request reprint [The status of regional long-term chemotherapy in liver metastasis]
    M Lorenz
    Klinik für Allgemein und Gefässchirurgie, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt a M
    Chirurg 70:141-53. 1999
    ..Overall, local long-term chemotherapy cannot be recommended outside of studies as a primary treatment. However, extensive experience and new drugs support the idea of conducting further regional studies...
  20. ncbi request reprint Impact of laparoscopic surgery on experimental hepatic metastases
    C N Gutt
    Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Br J Surg 88:371-5. 2001
    ..Metastatic disease to the liver is one of the major factors determining outcome after colonic resection with curative intention. The influence of laparoscopic surgery on metastatic disease in the liver is still largely unknown...
  21. ncbi request reprint Phase II study of weekly 24-hour intra-arterial high-dose infusion of 5-fluorouracil and folinic acid for liver metastases from colorectal carcinomas
    M Lorenz
    Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Frankfurt, Germany
    Ann Oncol 12:321-5. 2001
    ..A multicenter phase II trial was initiated in order to evaluate the weekly, high-dose 24-hour infusion of 5-fluorouracil (5-FU) plus folinic acid (FA) in patients with unresectable colorectal cancer hepatic metastases...
  22. ncbi request reprint CO2 environment influences the growth of cultured human cancer cells dependent on insufflation pressure
    C N Gutt
    Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Theodor Ster Kai 7, Frankfurt Main, Germany
    Surg Endosc 15:314-8. 2001
    ..Therefore, we designed a study to investigate the influence of CO2 insufflation administered at different pressures on the growth of cultured human tumor cells...
  23. ncbi request reprint Radioisotope-guided surgery in patients with pheochromocytoma and recurrent medullary thyroid carcinoma: a comparison of preoperative and intraoperative tumor localization with histopathologic findings
    S Adams
    Department of Nuclear Medicine, Johann Wolfgang Goethe University Medical Center, Frankfurt Main, Germany
    Cancer 92:263-70. 2001
    ....
  24. ncbi request reprint Influence of laparoscopy and laparotomy on systemic and peritoneal T lymphocytes in a rat model
    C N Gutt
    Department of General and Vascular Surgery, Johann Wolfgang Goethe University, Frankfurt, Germany
    Int J Colorectal Dis 16:216-20. 2001
    ..The mechanical pressure of the pneumoperitoneum seems to aggravate peritoneal T lymphocytes...
  25. ncbi request reprint Bethesda guidelines: relation to microsatellite instability and MLH1 promoter methylation in patients with colorectal cancer
    J Raedle
    Second Department of Internal Medicine, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt am Main, Germany
    Ann Intern Med 135:566-76. 2001
    ..The Bethesda guidelines were established to identify patients with colorectal cancer who should be tested for microsatellite instability...
  26. ncbi request reprint Relevance of locoregional chemotherapy in patients with liver metastases from colorectal primaries
    M Lorenz
    Department of General and Vascular Surgery, University Hospital of Frankfurt, Germany
    Swiss Surg 6:11-22. 2000
    ..Further evaluations on this technique should only be performed in experienced centers...
  27. ncbi request reprint Relevance of Ki-67 antigen expression and K-ras mutation in colorectal liver metastases
    H Petrowsky
    Department of General and Vascular Surgery, Johann Wolfgang Goethe University, 60590 Frankfurt am Main, Germany
    Eur J Surg Oncol 27:80-7. 2001
    ..The presence of K- ras mutations does not appear to correlate with tumour proliferation status or patient survival...
  28. doi request reprint In-hospital complication rates after stent treatment of 388 symptomatic intracranial stenoses: results from the INTRASTENT multicentric registry
    Wiebke Kurre
    Department of Neuroradiology, University of Frankfurt, Schleusenweg 2 16, 60528 Frankfurt, Germany
    Stroke 41:494-8. 2010
    ..Data from the INTRASTENT multicentric registry should demonstrate in-hospital complications at the current stage of clinical development of the stent procedure...
  29. ncbi request reprint Distal gastric cancer and extensive surgery: a new evaluation method based on the study of the status of residual lymph nodes after limited surgery
    D H Roukos
    Department of Surgery, University Hospital of Frankfurt, Frankfurt am Main, Germany
    Ann Surg Oncol 7:719-26. 2000
    ..We conducted a prospective study on patients who had undergone a D2 TG to evaluate whether certain stations left behind after a D1 SG contain metastasis...
  30. ncbi request reprint Predicting creatinine clearance by a simple formula following live-donor kidney transplantation
    C Zapletal
    Department of Surgery, Knappschaftskrankenhaus Bochum Langendreer, Ruhr University, In der Schornau 23 25, 44892, Bochum, Germany
    Transpl Int 17:490-4. 2004
    ..Therefore, this formula could help to detect early complications in the post-transplantation course if the recipient's creatinine clearance drops below the predicted result...