Alexander Koch

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. pmc Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients
    Alexander Koch
    Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy, JW Goethe University Hospital, Theodor Stern Kai 7, Frankfurt am Main 60590, Germany
    Crit Care 15:R109. 2011
  2. doi Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia
    Waltraud Pfeilschifter
    Department of Neurology, University Hospital, Goethe University Frankfurt
    Biochem Biophys Res Commun 413:212-7. 2011
  3. pmc Attenuation of myocardial injury by HMGB1 blockade during ischemia/reperfusion is toll-like receptor 2-dependent
    Jan Mersmann
    Department of Anaesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Mediators Inflamm 2013:174168. 2013
  4. doi Systemic inflammation after aortic cross clamping is influenced by Toll-like receptor 2 preconditioning and deficiency
    Alexander Koch
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany
    J Surg Res 178:833-41. 2012

Collaborators

  • Kai Zacharowski
  • Matthias Schott
  • Stefan R Bornstein
  • Jan Mersmann
  • Waltraud Pfeilschifter
  • Franziska Iskandar
  • Ralf R Schumann
  • Kathrina Latsch
  • Vera Sprunck
  • Katharina Habeck
  • Rene Zimmermann
  • Andrea Huwiler
  • Marian Sujak
  • Christian Foerch
  • Josef Pfeilschifter
  • Helmuth Steinmetz
  • Bozena Czech-Zechmeister
  • Abdelhaq Rami
  • Ana Mirceska

Detail Information

Publications4

  1. pmc Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients
    Alexander Koch
    Clinic of Anaesthesiology, Intensive Care Medicine and Pain Therapy, JW Goethe University Hospital, Theodor Stern Kai 7, Frankfurt am Main 60590, Germany
    Crit Care 15:R109. 2011
    ..To investigate the link to systemic inflammation in this context, we additionally measured 10 different cytokines in the serum...
  2. doi Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia
    Waltraud Pfeilschifter
    Department of Neurology, University Hospital, Goethe University Frankfurt
    Biochem Biophys Res Commun 413:212-7. 2011
    ..This suggests that SphK2 activity is an important endogenous protective mechanism in cerebral ischemia and corroborates that the protective effect of FTY720 is mediated via phospho-FTY720...
  3. pmc Attenuation of myocardial injury by HMGB1 blockade during ischemia/reperfusion is toll-like receptor 2-dependent
    Jan Mersmann
    Department of Anaesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Goethe University, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany
    Mediators Inflamm 2013:174168. 2013
    ..We here provide evidence that absence of TLR2 signalling abrogates infarct-sparing effects of HMGB1 blockade...
  4. doi Systemic inflammation after aortic cross clamping is influenced by Toll-like receptor 2 preconditioning and deficiency
    Alexander Koch
    Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany
    J Surg Res 178:833-41. 2012
    ..The influence of TLR2 stimulation or deficiency on systemic cytokine release and organ damage after aortic cross clamping has not been evaluated yet...