Klaus Peter Hunfeld

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. request reprint
    Hunfeld K, Brade V. Antimicrobial susceptibility of Borrelia burgdorferi sensu lato: what we know, what we don't know, and what we need to know. Wien Klin Wochenschr. 2006;118:659-68 pubmed
    ..This review will summarize what is and what is not known about antimicrobial resistance in B. burgdorferi s.l. and will discuss open questions that continue to fuel the current debate on treatment-resistant Lyme borreliosis. ..
  2. Hunfeld K, Hildebrandt A, Gray J. Babesiosis: recent insights into an ancient disease. Int J Parasitol. 2008;38:1219-37 pubmed publisher
    ..This review covers recent insights into human babesiosis with regard to phylogeny, diagnostics and treatment in order to provide new information on well known as well as recently discovered parasites with zoonotic potential. ..
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    Hunfeld K, Brade V. Prevalence of antibodies against the human granulocytic ehrlichiosis agent in Lyme borreliosis patients from Germany. Eur J Clin Microbiol Infect Dis. 1999;18:221-4 pubmed
    ..6%). The findings indicate that concomitant or serial infections with Borrelia burgdorferi and the HGE agent or closely related organisms may be a common occurrence in tick-exposed patients from Germany. ..
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    Hunfeld K, Brade V. Zoonotic Babesia: possibly emerging pathogens to be considered for tick-infested humans in Central Europe. Int J Med Microbiol. 2004;293 Suppl 37:93-103 pubmed
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    Hunfeld K, Bittner T, Rödel R, Brade V, Cinatl J. New real-time PCR-based method for in vitro susceptibility testing of Anaplasma phagocytophilum against antimicrobial agents. Int J Antimicrob Agents. 2004;23:563-71 pubmed
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    Hunfeld K, Kraiczy P, Wichelhaus T, Schafer V, Brade V. New colorimetric microdilution method for in vitro susceptibility testing of Borrelia burgdorferi against antimicrobial substances. Eur J Clin Microbiol Infect Dis. 2000;19:27-32 pubmed
    ..The colorimetric microdilution method offered the advantages of reliability, reproducibility, and convenience and could handle large numbers of isolates and antibiotics. ..
  7. Hunfeld K, Wichelhaus T, Rödel R, Acker G, Brade V, Kraiczy P. Comparison of in vitro activities of ketolides, macrolides, and an azalide against the spirochete Borrelia burgdorferi. Antimicrob Agents Chemother. 2004;48:344-7 pubmed
    ..0019 micro g/ml) and telithromycin (MIC(90), 0.0078 micro g/ml). Electron-microscope analysis and time-kill studies also supported enhanced effectiveness of both ketolides. ..
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    Hunfeld K, Kraiczy P, Wichelhaus T, Schafer V, Brade V. Colorimetric in vitro susceptibility testing of penicillins, cephalosporins, macrolides, streptogramins, tetracyclines, and aminoglycosides against Borrelia burgdorferi isolates. Int J Antimicrob Agents. 2000;15:11-7 pubmed
    ..Our study showed excellent in vitro antimicrobial activity of all classes of antibiotics tested, except the aminoglycosides and hence their suitability for therapy of Lyme disease. ..
  9. request reprint
    Hunfeld K, Kraiczy P, Kekoukh E, Schäfer V, Brade V. Standardised in vitro susceptibility testing of Borrelia burgdorferi against well-known and newly developed antimicrobial agents--possible implications for new therapeutic approaches to Lyme disease. Int J Med Microbiol. 2002;291 Suppl 33:125-37 pubmed

More Information

Publications12

  1. Hunfeld K, Ruzic Sabljic E, Norris D, Kraiczy P, Strle F. In vitro susceptibility testing of Borrelia burgdorferi sensu lato isolates cultured from patients with erythema migrans before and after antimicrobial chemotherapy. Antimicrob Agents Chemother. 2005;49:1294-301 pubmed
    ..Therefore, resistance mechanisms other than acquired resistance to antimicrobial agents should be considered in patients with LB resistant to treatment. ..
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    Hunfeld K, Weigand J, Wichelhaus T, Kekoukh E, Kraiczy P, Brade V. In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin and fusidic acid against Borrelia burgdorferi. Int J Antimicrob Agents. 2001;17:203-8 pubmed
    ..burgdorferi complex. The excellent in vitro effectiveness of acylamino-penicillin derivatives and their suitability for the therapy of Lyme disease is emphasised. ..
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    Hunfeld K, Ernst M, Zachary P, Jaulhac B, Sonneborn H, Brade V. Development and laboratory evaluation of a new recombinant ELISA for the serodiagnosis of Lyme disease. Wien Klin Wochenschr. 2002;114:580-5 pubmed
    ..The aim of the present study was to develop and evaluate a new recombinant ELISA (RE) for the detection of specific IgG and IgM antibodies against Borrelia burgdorferi...