W P Hofmann

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. pmc Baseline MELD score predicts hepatic decompensation during antiviral therapy in patients with chronic hepatitis C and advanced cirrhosis
    Georg Dultz
    Medizinische Klinik 1, Klinikum der Goethe Universität, Frankfurt am Main, Germany
    PLoS ONE 8:e71262. 2013
  2. pmc Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers
    Johannes Vermehren
    Medizinische Klinik 1, Klinikum der J, W, Goethe Universitat, Frankfurt am Main, Germany
    BMC Gastroenterol 12:27. 2012
  3. ncbi Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir
    Wolf Peter Hofmann
    Department of Internal Medicine I, Goethe University Hospital, Frankfurt, Germany
    Antivir Ther 16:695-704. 2011
  4. doi [Prediction of perioperative mortality in patients with advanced liver disease and abdominal surgery by the use of different scoring systems and tests]
    W P Hofmann
    Medizinische Klinik 1, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main
    Z Gastroenterol 46:1283-9. 2008
  5. doi Effect of ribavirin on the frequency of RNase L cleavage sites within the hepatitis C viral genome
    U Mihm
    Medizinische Klinik I, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt Main, Germany
    J Viral Hepat 17:217-21. 2010
  6. doi Dynamics of hepatitis B virus quasispecies heterogeneity and virologic response in patients receiving low-to-moderate genetic barrier nucleoside analogs
    J Peveling-Oberhag
    Department of Internal Medicine 1, J W Goethe University Hospital, Frankfurt, Germany
    J Viral Hepat 20:234-9. 2013
  7. doi Comparison of envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates
    M W Welker
    Klinikum der Johann Wolfgang Goethe Universitat, Medizinische Klinik 1, Frankfurt am Main, Germany
    J Viral Hepat 18:181-92. 2011
  8. doi Dysregulation of global microRNA expression in splenic marginal zone lymphoma and influence of chronic hepatitis C virus infection
    J Peveling-Oberhag
    Department of Internal Medicine 1, J W Goethe University Hospital, Frankfurt, Germany
    Leukemia 26:1654-62. 2012
  9. doi Prospective study of bone mineral density and metabolism in patients with chronic hepatitis C during pegylated interferon alpha and ribavirin therapy
    W P Hofmann
    Department of Internal Medicine I, Johann Wolfgang Goethe University Hospital, Frankfurt, Germany
    J Viral Hepat 15:790-6. 2008
  10. ncbi Primary actinomycosis of the liver mimicking malignancy
    C M Lange
    Medizinische Klinik 1, J W Goethe Universitätsklinikum, Frankfurt am Main
    Z Gastroenterol 47:1062-4. 2009

Collaborators

Detail Information

Publications10

  1. pmc Baseline MELD score predicts hepatic decompensation during antiviral therapy in patients with chronic hepatitis C and advanced cirrhosis
    Georg Dultz
    Medizinische Klinik 1, Klinikum der Goethe Universität, Frankfurt am Main, Germany
    PLoS ONE 8:e71262. 2013
    ..However, predictive factors associated with hepatic decompensation during antiviral therapy are poorly defined...
  2. pmc Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers
    Johannes Vermehren
    Medizinische Klinik 1, Klinikum der J, W, Goethe Universitat, Frankfurt am Main, Germany
    BMC Gastroenterol 12:27. 2012
    ..Our aim was to determine the prevalence of liver fibrosis and associated risk factors in HIV-infected individuals based on non-invasive fibrosis assessment using transient elastography (TE) and serum biomarkers (Fibrotest [FT])...
  3. ncbi Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir
    Wolf Peter Hofmann
    Department of Internal Medicine I, Goethe University Hospital, Frankfurt, Germany
    Antivir Ther 16:695-704. 2011
    ..Ribavirin increases early and sustained virological response rates in patients chronically infected with HCV who receive pegylated interferon-α and novel HCV protease inhibitors...
  4. doi [Prediction of perioperative mortality in patients with advanced liver disease and abdominal surgery by the use of different scoring systems and tests]
    W P Hofmann
    Medizinische Klinik 1, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main
    Z Gastroenterol 46:1283-9. 2008
    ..Besides other dynamic tests, the indocyanine green (ICG) clearance and the monoethylglycinxylid (MEGX) clearance tests have been satisfactorily evaluated...
  5. doi Effect of ribavirin on the frequency of RNase L cleavage sites within the hepatitis C viral genome
    U Mihm
    Medizinische Klinik I, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt Main, Germany
    J Viral Hepat 17:217-21. 2010
    ..In conclusion, Ribavirin-induced mutagenesis did not increase RNase L cleavage sites (UU/UA dinucleotides) within the HCV NS3 or NS5B encoding regions...
  6. doi Dynamics of hepatitis B virus quasispecies heterogeneity and virologic response in patients receiving low-to-moderate genetic barrier nucleoside analogs
    J Peveling-Oberhag
    Department of Internal Medicine 1, J W Goethe University Hospital, Frankfurt, Germany
    J Viral Hepat 20:234-9. 2013
    ..Further studies are needed to confirm HBV quasispecies evolution as additional predictive marker for beneficial treatment outcome...
  7. doi Comparison of envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates
    M W Welker
    Klinikum der Johann Wolfgang Goethe Universitat, Medizinische Klinik 1, Frankfurt am Main, Germany
    J Viral Hepat 18:181-92. 2011
    ..026). CD81 expression on PBMC was not correlated with the number of mutations within the CD81 binding regions...
  8. doi Dysregulation of global microRNA expression in splenic marginal zone lymphoma and influence of chronic hepatitis C virus infection
    J Peveling-Oberhag
    Department of Internal Medicine 1, J W Goethe University Hospital, Frankfurt, Germany
    Leukemia 26:1654-62. 2012
    ..0016). In conclusion, there is a characteristic dysregulation of miRNA expression in SMZL with a possible implication in its molecular tumorigenesis...
  9. doi Prospective study of bone mineral density and metabolism in patients with chronic hepatitis C during pegylated interferon alpha and ribavirin therapy
    W P Hofmann
    Department of Internal Medicine I, Johann Wolfgang Goethe University Hospital, Frankfurt, Germany
    J Viral Hepat 15:790-6. 2008
    ..Antiviral therapy leads to an on-treatment increase of BMD, which may last in those patients who achieve a sustained virological response...
  10. ncbi Primary actinomycosis of the liver mimicking malignancy
    C M Lange
    Medizinische Klinik 1, J W Goethe Universitätsklinikum, Frankfurt am Main
    Z Gastroenterol 47:1062-4. 2009
    ..However, histological investigations revealed a rare case of primary actinomycosis of the liver which was successfully treated with antibiotics...