Stephan Fichtlscherer

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. ncbi request reprint [Endothelial dysfunction in patients with acute coronary syndrome]
    S Fichtlscherer
    Abteilung Kardiologie, Johann Wolfgang Goethe Universitat Frankfurt
    Herz 24:534-43. 1999
  2. ncbi request reprint Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for 'pleiotropic' functions of statin therapy
    Stephan Fichtlscherer
    Department of Internal Medicine III, Division of Cardiology, Johann W Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Eur Heart J 27:1182-90. 2006
  3. ncbi request reprint Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes: further evidence for the existence of the "vulnerable" patient
    Stephan Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Circulation 110:1926-32. 2004
  4. ncbi request reprint Elevated secretory non-pancreatic type II phospholipase A2 serum activity is associated with impaired endothelial vasodilator function in patients with coronary artery disease
    Stephan Fichtlscherer
    Division of Cardiology, Department of Internal Medicine IV, Johann W Goethe University, 60590 Frankfurt, Germany
    Clin Sci (Lond) 106:511-7. 2004
  5. ncbi request reprint C-reactive protein levels determine systemic nitric oxide bioavailability in patients with coronary artery disease
    Stephan Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Eur Heart J 25:1412-8. 2004
  6. ncbi request reprint Interleukin-10 serum levels and systemic endothelial vasoreactivity in patients with coronary artery disease
    Stephan Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Frankfurt, Germany
    J Am Coll Cardiol 44:44-9. 2004
  7. doi request reprint Procedural safety and predictors of acute outcome of intracoronary administration of progenitor cells in 775 consecutive procedures performed for acute myocardial infarction or chronic heart failure
    Salvatore De Rosa
    Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Germany
    Circ Cardiovasc Interv 6:44-51. 2013
  8. doi request reprint Impact of interventional strategy for unprotected left main coronary artery percutaneous coronary intervention on long-term survival
    Ralf Lehmann
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, Frankfurt, Germany
    Can J Cardiol 28:553-60. 2012
  9. doi request reprint Prognostic impact of using drug-eluting-stents on outcome and strategy in multivessel PCI: data from the Frankfurt MV-PCI registry
    Thomas Schwietz
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    J Cardiol 61:38-43. 2013
  10. ncbi request reprint Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis
    Christopher Heeschen
    Molecular Cardiology, Department of Internal Medicine III, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    J Am Coll Cardiol 45:229-37. 2005

Collaborators

Detail Information

Publications57

  1. ncbi request reprint [Endothelial dysfunction in patients with acute coronary syndrome]
    S Fichtlscherer
    Abteilung Kardiologie, Johann Wolfgang Goethe Universitat Frankfurt
    Herz 24:534-43. 1999
    ..Both of these are often temporarily limited. Therefore, "non-invasive examination" of endothelial function by venous occlusion plethysmography or high resolution ultrasound might be useful for monitoring high-risk patients...
  2. ncbi request reprint Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for 'pleiotropic' functions of statin therapy
    Stephan Fichtlscherer
    Department of Internal Medicine III, Division of Cardiology, Johann W Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Eur Heart J 27:1182-90. 2006
    ..The clinical availability of ezetimibe, a potent novel cholesterol absorption inhibitor, enables to differentiate lipid-lowering effects from potential non-lipid-lowering (pleiotropic) mechanisms of statins...
  3. ncbi request reprint Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes: further evidence for the existence of the "vulnerable" patient
    Stephan Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    Circulation 110:1926-32. 2004
    ....
  4. ncbi request reprint Elevated secretory non-pancreatic type II phospholipase A2 serum activity is associated with impaired endothelial vasodilator function in patients with coronary artery disease
    Stephan Fichtlscherer
    Division of Cardiology, Department of Internal Medicine IV, Johann W Goethe University, 60590 Frankfurt, Germany
    Clin Sci (Lond) 106:511-7. 2004
    ..The identification of sPLA(2) as a novel independent predictor for endothelial dysfunction provides another important clue to link a systemic marker of inflammation with coronary atherosclerotic disease...
  5. ncbi request reprint C-reactive protein levels determine systemic nitric oxide bioavailability in patients with coronary artery disease
    Stephan Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Eur Heart J 25:1412-8. 2004
    ..Because inflammatory cytokines experimentally reduce basal and stimulated endothelial nitric oxide (NO) release, we hypothesised that patients with elevated CRP-levels are characterised by a systemic impairment in NO bioavailability...
  6. ncbi request reprint Interleukin-10 serum levels and systemic endothelial vasoreactivity in patients with coronary artery disease
    Stephan Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Frankfurt, Germany
    J Am Coll Cardiol 44:44-9. 2004
    ..Because the endothelium is a major target for inflammatory cytokines, we investigated whether elevated interleukin (IL)-10 serum levels are associated with improved endothelial vasoreactivity in patients with coronary artery disease (CAD)...
  7. doi request reprint Procedural safety and predictors of acute outcome of intracoronary administration of progenitor cells in 775 consecutive procedures performed for acute myocardial infarction or chronic heart failure
    Salvatore De Rosa
    Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Germany
    Circ Cardiovasc Interv 6:44-51. 2013
    ..Therefore, we analyzed periprocedural complications and 30-day outcome in 775 consecutive procedures of intracoronary administration of progenitor cells using the stop-flow technique...
  8. doi request reprint Impact of interventional strategy for unprotected left main coronary artery percutaneous coronary intervention on long-term survival
    Ralf Lehmann
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, Frankfurt, Germany
    Can J Cardiol 28:553-60. 2012
    ..In cases involving the left anterior descending-left circumflex bifurcation, the optimal interventional strategy remains unclear. Randomized bifurcation trials in the past excluded ULMCA lesions...
  9. doi request reprint Prognostic impact of using drug-eluting-stents on outcome and strategy in multivessel PCI: data from the Frankfurt MV-PCI registry
    Thomas Schwietz
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    J Cardiol 61:38-43. 2013
    ..The aim of this study was to evaluate the prognostic impact of the introduction of DES in patients undergoing multivessel percutaneous coronary intervention (MV-PCI)...
  10. ncbi request reprint Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis
    Christopher Heeschen
    Molecular Cardiology, Department of Internal Medicine III, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    J Am Coll Cardiol 45:229-37. 2005
    ..The goal of this study was to determine the predictive value of pregnancy-associated plasma protein-A (PAPP-A) in patients with acute coronary syndromes (ACS)...
  11. doi request reprint Complete revascularization in patients undergoing multivessel PCI is an independent predictor of improved long-term survival
    Ralf Lehmann
    Department of Cardiology, Goethe University Frankfurt, Frankfurt, Germany
    J Interv Cardiol 23:256-63. 2010
    ..In addition, different definitions of CR have further complicated the interpretation of clinical studies...
  12. pmc Quantification of circulating endothelial progenitor cells using the modified ISHAGE protocol
    Caroline Schmidt-Lucke
    Department of Molecular Cardiology, Internal Medicine III, J W Goethe University, Frankfurt, Germany
    PLoS ONE 5:e13790. 2010
    ..We, therefore developed a novel protocol adapted from the standardised so-called ISHAGE protocol for enumeration of haematopoietic stem cells to enable comparison of clinical and laboratory data...
  13. ncbi request reprint Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease
    Stephan Fichtlscherer
    Departments of Internal Medicine IV, Division of Cardiology, Johann W Goethe University, Frankfurt am Main, Germany
    Circulation 109:178-83. 2004
    ..Here, we studied the involvement of CYP 2C9 in modulating endothelium-dependent and -independent changes in forearm blood flow (FBF) in healthy volunteers and in patients with manifest coronary artery disease...
  14. doi request reprint Improvement of endothelial damage and regeneration indexes in patients with coronary artery disease after 4 weeks of statin therapy
    Caroline Schmidt-Lucke
    Department of Internal Medicine III, Johann W Goethe University Frankfurt, Germany
    Atherosclerosis 211:249-54. 2010
    ..The availability of ezetimibe, a potent novel cholesterol absorption inhibitor, allows to distinguish between lipid-lowering and pleiotropic properties of statins...
  15. doi request reprint Early remodeling processes as predictors of diastolic function 5 years after reperfused acute myocardial infarction and intracoronary progenitor cell application
    Ulrich Fischer-Rasokat
    Division of Cardiology, Department of Medicine III, Goethe University of Frankfurt, Theodor Stern Kai 7, 60590, Frankfurt, Germany
    Clin Res Cardiol 101:209-16. 2012
    ..Therefore, we aimed to identify AMI characteristics, which determine diastolic function after 5 years...
  16. ncbi request reprint Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair
    Caroline Schmidt-Lucke
    Molecular Cardiology, Department of Medicine III, J W Goethe University, Frankfurt, Germany
    Circulation 111:2981-7. 2005
    ..Circulating EPCs may thus provide an endogenous repair mechanism to counteract ongoing risk factor-induced endothelial injury and to replace dysfunctional endothelium...
  17. ncbi request reprint Prognostic value of placental growth factor in patients with acute chest pain
    Christopher Heeschen
    Department of Cardiology, Johann Wolfgang Goethe University, Frankfurt, Germany
    JAMA 291:435-41. 2004
    ....
  18. doi request reprint Favorable long-term survival in patients undergoing multivessel-PCI compared to predicted prognosis of CABG estimated by EuroSCORE: procedural and clinical determinants of long-term outcome
    Ralf Lehmann
    Department of Cardiology, Johann Wolfgang Goethe University, Frankfurt, Germany
    J Interv Cardiol 22:511-9. 2009
    ..Expected in-hospital mortality for CABG was calculated using the EuroSCORE and compared to the observed mortality rate during in-hospital as well as long-term follow-up...
  19. ncbi request reprint Serum level of the antiinflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes
    Christopher Heeschen
    Department of Internal Medicine IV, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Circulation 107:2109-14. 2003
    ..Therefore, we investigated the prognostic impact of key inflammatory players, namely the inflammatory marker C-reactive protein (CRP) and the antiinflammatory cytokine interleukin-10 (IL-10), in patients with acute coronary syndromes...
  20. doi request reprint Risk stratification following complex PCI: clinical versus anatomical risk stratification including "post PCI residual SYNTAX-score" as quantification of incomplete revascularization
    Thomas Schwietz
    Department of Cardiology, Goethe University Frankfurt, Frankfurt, Germany
    J Interv Cardiol 26:29-37. 2013
    ..The SYNTAX-Score has also been proposed to predict clinical outcome. The prognostic impact of these scores to predict long-term survival after PCI has not yet been compared...
  21. doi request reprint Transcoronary concentration gradients of circulating microRNAs
    Salvatore De Rosa
    Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Frankfurt, Germany
    Circulation 124:1936-44. 2011
    ....
  22. ncbi request reprint FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells
    Carmen Urbich
    Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Frankfurt, Germany
    FASEB J 19:974-6. 2005
    ..In summary, our results show that FOXO-dependent expression of Bim plays a pivotal role for EPC apoptosis. Statins reduce oxidative stress-induced EPC apoptosis, inactivate FOXO4, and down-regulate Bim...
  23. doi request reprint Transcatheter aortic valve implantation improves outcome compared to open-heart surgery in kidney transplant recipients requiring aortic valve replacement
    Henrik Fox
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    J Cardiol 61:423-7. 2013
    ....
  24. doi request reprint Safety and feasibility of transcatheter aortic valve implantation in patients with severe persistent thrombocytopenia
    Henrik Fox
    aDepartment of Cardiology bDepartment of Heart Surgery, Johann Wolfgang Goethe University Frankfurt, Frankfurt, Germany
    Blood Coagul Fibrinolysis 24:732-5. 2013
    ..The indication for TAVI in patients with thrombocytopenia and symptomatic high-grade aortic stenosis might be generated independently from conventional scoring systems...
  25. doi request reprint Impact of aortic valve calcification on the outcome of transcatheter aortic valve implantation: results from the prospective multicenter German TAVI registry
    Stephan Staubach
    CardioVascular Center Frankfurt, Sankt Katharinen und Universitätsklinikum Frankfurt, Frankfurt, Germany
    Catheter Cardiovasc Interv 81:348-55. 2013
    ..Transcatheter aortic valve implantation (TAVI) is an emerging technology in patients with severe aortic stenosis...
  26. pmc The STS score is the strongest predictor of long-term survival following transcatheter aortic valve implantation, whereas access route (transapical versus transfemoral) has no predictive value beyond the periprocedural phase
    Katrin Hemmann
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, Frankfurt, Germany
    Interact Cardiovasc Thorac Surg 17:359-64. 2013
    ..However, no appropriate risk score to predict long-term outcome following TAVI is currently available. The aim of this study was to identify predictors of adverse short- and long-term outcomes...
  27. doi request reprint Characterization of levels and cellular transfer of circulating lipoprotein-bound microRNAs
    Jasmin Wagner
    Institute of Cardiovascular Regeneration, Centre for Molecular Medicine, Goethe University Frankfurt, Frankfurt, Germany
    Arterioscler Thromb Vasc Biol 33:1392-400. 2013
    ..Here, we evaluate the regulation and potential function of HDL- and low-density lipoprotein-bound miRs isolated from healthy subjects and patients with coronary artery disease...
  28. doi request reprint Microvascular dysfunction and pulse wave reflection characterize different vascular pathologies in patients at cardiovascular risk
    Ulrich Fischer-Rasokat
    Division of Cardiology, Department of Medicine III, Goethe University Hospital, Frankfurt Main, Germany
    Vasa 41:192-9. 2012
    ..In this study we assessed the interrelationships among these noninvasive measures of vascular function...
  29. doi request reprint Systemic therapy of plaque-type psoriasis ameliorates endothelial cell function: results of a prospective longitudinal pilot trial
    Sandra Boehncke
    Department of Internal Medicine, Clinic of the Johann Wolfgang Goethe University, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    Arch Dermatol Res 303:381-8. 2011
    ..Future studies need to compare the cardioprotective effects of different treatment modalities, based on hard end points such as the rate of myocardial infarction...
  30. ncbi request reprint Inflammatory markers and coronary artery disease
    Stephan Fichtlscherer
    Johann W Goethe University, Department of Cardiology, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Curr Opin Pharmacol 4:124-31. 2004
    ..As a result, different markers are used clinically for risk stratification in stable coronary artery disease as well as in acute coronary syndromes...
  31. doi request reprint Favorable long-term survival in patients undergoing stent PCI of unprotected left main coronary artery compared to predicted short-term prognosis of CABG estimated by EuroSCORE: clinical determinants of long-term outcome
    Ralf Lehmann
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, D 60590 Frankfurt, Germany
    J Interv Cardiol 22:311-9. 2009
    ..8 +/- 1.2 years)...
  32. ncbi request reprint Benefits of immediate initiation of statin therapy following successful coronary stent implantation in patients with stable and unstable angina pectoris and Q-wave acute myocardial infarction
    Dirk H Walter
    Department of Internal Medicine IV, Division of Cardiology, University of Frankfurt, Germany
    Am J Cardiol 89:1-6. 2002
    ....
  33. doi request reprint Circulating microRNAs: biomarkers or mediators of cardiovascular diseases?
    Stephan Fichtlscherer
    Division of Cardiology, Department of Medicine III, Goethe University, Frankfurt, Germany
    Arterioscler Thromb Vasc Biol 31:2383-90. 2011
    ..In addition, the mechanisms by which miRs are released and their putative function as long-distance communicators are discussed...
  34. ncbi request reprint The pro-apoptotic serum activity is an independent mortality predictor of patients with heart failure
    Lothar Rossig
    Division of Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Eur Heart J 25:1620-5. 2004
    ..Since serum of patients with HF induces apoptosis of endothelial cells (EC), we aimed to determine whether the pro-apoptotic activity in the serum may predict prognosis of patients with HF...
  35. doi request reprint Caffeine enhances endothelial repair by an AMPK-dependent mechanism
    Ioakim Spyridopoulos
    Department of Internal Medicine III, University of Frankfurt, Germany
    Arterioscler Thromb Vasc Biol 28:1967-74. 2008
    ..Migratory capacity of endothelial progenitor cells (EPCs) and mature endothelial cells (ECs) is a key prerequisite for endothelial repair after denuding injury or endothelial damage...
  36. doi request reprint Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium
    Volker Schachinger
    Department of Medicine III, Division of Cardiology, JW Goethe University Frankfurt, Frankfurt am Main, Germany
    Circulation 118:1425-32. 2008
    ..The extent and potential determinants of proangiogenic progenitor cell homing into the damaged myocardium after intracoronary infusion and the underlying mechanisms are still unknown...
  37. doi request reprint Implementation of the transradial approach for coronary procedures is not associated with an elevated complication rate and elevated radiation patient exposure
    Ralf Lehmann
    Department of Cardiology, Johann Wolfgang Goethe University Frankfurt, Theodor Stern Kai 7, D 60590 Frankfurt, Germany
    J Interv Cardiol 24:56-64. 2011
    ..The transradial approach for coronary procedures is associated with a low complication rate, but specific training is considered mandatory...
  38. ncbi request reprint Tumor necrosis factor antagonism with etanercept improves systemic endothelial vasoreactivity in patients with advanced heart failure
    S Fichtlscherer
    Department of Internal Medicine IV, Division of Cardiology, Johann W. Goethe-University Frankfurt, Germany
    Circulation 104:3023-5. 2001
    ..Improvement of systemic endothelial function might importantly contribute to the beneficial effects of etanercept on the functional status of patients with CHF...
  39. doi request reprint Risk for permanent pacemaker after transcatheter aortic valve implantation: a comprehensive analysis of the literature
    Damir Erkapic
    Division of Clinical Electrophysiology, Department of Cardiology, J W Goethe University, Frankfurt, Germany
    J Cardiovasc Electrophysiol 23:391-7. 2012
    ..Permanent pacemaker (PM) requirement is a known complication after transcatheter aortic valve implantation (TAVI). There are, however, no systematic data concerning this complication...
  40. ncbi request reprint Statin therapy in patients with coronary artery disease improves the impaired endothelial progenitor cell differentiation into cardiomyogenic cells
    Stefan Rupp
    Molecular Cardiology, Dept of Internal Medicine IV, University of Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, Germany
    Basic Res Cardiol 99:61-8. 2004
    ..1 micro M atorvastatin did not affect EPC differentiation (116.15% +/- 49.11% of control).EPCs from patients with CAD display impaired differentiation into cardiomyogenic cells. This defect can be improved by in vivo, statin therapy...
  41. ncbi request reprint The endothelium and inflammation
    Thomas Trepels
    Department of Internal Medicine III, Division of Cardiology, Johann Wolfgang Goethe University, Frankfurt, Germany
    Endothelium 13:423-9. 2006
    ....
  42. ncbi request reprint Progress in CT imaging for the cardiac surgeon
    Christopher Herzog
    Institute for Diagnostic and Interventional Radiology, J W Goethe University, Frankfurt, Germany
    Semin Thorac Cardiovasc Surg 16:242-8. 2004
    ..New technological developments such as 64-row MDCT or flat panel computed tomography will further increase the field of possible indications...
  43. doi request reprint Angiotensin-converting enzyme (ACE) inhibitors modulate cellular retinol-binding protein 1 and adiponectin expression in adipocytes via the ACE-dependent signaling cascade
    Karin Kohlstedt
    Institute for Vascular Signaling, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Mol Pharmacol 75:685-92. 2009
    ..The latter may contribute to the beneficial effects of ACE inhibitors on the development of type 2 diabetes in patients with an activated renin-angiotensin system...
  44. ncbi request reprint [Analysis of forearm circulation--a substitute for diagnosis of coronary atherosclerosis?]
    G Rosenberger
    Medizinische Klinik IV, Abteilung fur Kardiologie, Johann Wolfgang Goethe Universitat Frankfurt
    Herz 23:130-4. 1998
    ....
  45. pmc HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway
    S Dimmeler
    Division of Molecular Cardiology, Department of Medicine IV, University of Frankfurt, Frankfurt, Germany
    J Clin Invest 108:391-7. 2001
    ....
  46. ncbi request reprint Statin therapy, inflammation and recurrent coronary events in patients following coronary stent implantation
    D H Walter
    Department of Internal Medicine IV, Division of Cardiology, University of Frankfurt, Frankfurt, Germany
    J Am Coll Cardiol 38:2006-12. 2001
    ....
  47. ncbi request reprint Preprocedural C-reactive protein levels and cardiovascular events after coronary stent implantation
    D H Walter
    Department of Internal Medicine IV, University of Frankfurt, Germans
    J Am Coll Cardiol 37:839-46. 2001
    ..This study assessed the predictive value of preprocedural C-reactive protein (CRP) levels on six-month clinical and angiographic outcome in patients undergoing coronary stent implantation...
  48. ncbi request reprint Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease
    Dirk H Walter
    Molecular Cardiology, Department of Internal Medicine III, University of Frankfurt, Frankfurt, Germany
    Circ Res 97:1142-51. 2005
    ..Stimulating CXCR4 signaling might improve functional properties of EPC and may rescue impaired neovascularization capacity of EPC derived from patients with CAD...
  49. ncbi request reprint Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease
    M Vasa
    Division of Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Theodor-Stern-Kai 7, Frankfurt, Germany
    Circulation 103:2885-90. 2001
    ..Given the well-established role of EPCs of participating in repair after ischemic injury, stimulation of EPCs by statins may contribute to the clinical benefit of statin therapy in patients with CAD...
  50. ncbi request reprint Changing incidence and prognostic factors of survival in AIDS-related non-Hodgkin's lymphoma in the era of highly active antiretroviral therapy (HAART)
    Timo Wolf
    Department of Internal Medicine III, Hematology, Oncology and Infectious Diseases, University Hospital Frankfurt, Germany
    Leuk Lymphoma 46:207-15. 2005
    ....
  51. doi request reprint Circulating microRNAs in patients with coronary artery disease
    Stephan Fichtlscherer
    Institute for Cardiovascular Regeneration, Goethe University Frankfurt, Theodor Stern Kai 7, Frankfurt, Germany
    Circ Res 107:677-84. 2010
    ..MicroRNAs are small RNAs that control gene expression. Besides their cell intrinsic function, recent studies reported that microRNAs are released by cultured cells and can be detected in the blood...
  52. doi request reprint Percutaneous mitral valve repair with the MitraClip® system under deep sedation and local anaesthesia
    Tobias Teufel
    CardioVascular Center Frankfurt, Sankt Katharinen and University Hospital, Frankfurt, Germany
    EuroIntervention 8:587-90. 2012
    ..We report our initial experience in the use of the MitraClip® system under deep sedation and local anaesthesia in five consecutive cases...
  53. ncbi request reprint Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    M Vasa
    Division of Molecular Cardiology, Department of Internal Medicine IV, University of Frankfurt, Germany
    Circ Res 89:E1-7. 2001
    ..The full text of this article is available at http://www.circresaha.org...
  54. ncbi request reprint Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
    Christopher Heeschen
    Department of Internal Medicine IV and Hematology, University of Frankfurt, Germany
    Blood 102:1340-6. 2003
    ..Epo appears to physiologically regulate EPC mobilization in patients with ischemic heart disease. Thus, Epo serum levels may help in identifying patients with impaired EPC recruitment capacity...
  55. ncbi request reprint Transcoronary transplantation of functionally competent BMCs is associated with a decrease in natriuretic peptide serum levels and improved survival of patients with chronic postinfarction heart failure: results of the TOPCARE-CHD Registry
    Birgit Assmus
    Cardiology and Molecular Cardiology, Department of Medicine III, J W Goethe University of Frankfurt, Germany
    Circ Res 100:1234-41. 2007
    ..Importantly, infusion of progenitor cells with a high functional capacity is associated with a significantly lower mortality during further follow-up...
  56. ncbi request reprint Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes
    Timo Lenderink
    Department of Cardiology, Atrium Medical Centre, Heerlen, The Netherlands
    J Am Coll Cardiol 47:307-11. 2006
    ..This study sought to evaluate the predictive value of baseline placental growth factor (PlGF) for long-term cardiovascular events in acute coronary syndromes (ACS)...
  57. ncbi request reprint [Acute coronary syndrome and inflammation. Biomarkers for diagnostics and risk stratification]
    Thomas Trepels
    Medizinische Klinik IV, Kardiologie, Klinikum der Johann Wolfgang Goethe Universitat, Frankfurt am Main
    Herz 29:769-76. 2004
    ..However, the clinical utility of these novel markers has not been established so far...