Markus T Bohnsack
Affiliation: Frankfurt am Main
- Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesisMarkus T Bohnsack
Wellcome Trust Centre for Cell Biology, University of Edinburgh, UK
Mol Cell 36:583-92. 2009..We propose that Prp43 acts on preribosomal regions surrounding each binding site, with distinct functions at different locations...
- Quantitative analysis of snoRNA association with pre-ribosomes and release of snR30 by Rok1 helicaseMarkus T Bohnsack
Wellcome Trust Centre for Cell Biology, University of Edinburgh, King s Buildings, Mayfield Road, Edinburgh EH9 3JR, UK
EMBO Rep 9:1230-6. 2008..Dissociation of U3 and U14 from pre-ribosomes is also dependent on helicases, suggesting that release of the essential snoRNAs might differ mechanistically from release of the modification-guide snoRNAs...
- The mRNA encoding the yeast ARE-binding protein Cth2 is generated by a novel 3' processing pathwayDelphine Ciais
Wellcome Trust Centre for Cell Biology, University of Edinburgh, EH9 3JR, UK
Nucleic Acids Res 36:3075-84. 2008..We propose that CTH2 mRNA is processed from a 3'-extended primary transcript by the exosome, TRAMP and Nrd1/Nab3/Sen1 complexes. This unusual pathway may allow time for nuclear, ARE-mediated regulation of CTH2 levels involving Rat1...