Annemarie Berger

Summary

Affiliation: Frankfurt am Main
Country: Germany

Publications

  1. doi request reprint Case report: risk of virus infection after accidental blood inoculation from a multi-infected AIDS patient
    Annemarie Berger
    Institute of Medical Virology, Hospital of Johann Wolfgang Goethe University, Frankfurt M, Germany
    J Med Virol 84:897-900. 2012
  2. ncbi request reprint [Antiviral treatment of chronic hepatitis C]
    Annemarie Berger
    Institut fur Medizinische Virologie, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Str 40, 60596 Frankfurt am Main
    Med Monatsschr Pharm 35:55-60. 2012
  3. ncbi request reprint Measurements of HCV neutralizing antibodies and of HCV-specific CD4+ and CD8+ cells using hepatitis C virus pseudo-particles (HCVpp)
    Annemarie Berger
    Institut fur Medizinische Virologie, Klinikum der J W Goethe Universitat, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 46:55-60. 2009
  4. ncbi request reprint HBV reactivation after kidney transplantation
    Annemarie Berger
    Institute for Medical Virology, Center of Internal Medicine, J W Goethe University Hospital, Paul Ehrlich Str 40, D 60596 Frankfurt a M, Germany
    J Clin Virol 32:162-5. 2005
  5. ncbi request reprint Comparative evaluation of the Cobas Amplicor HIV-1 Monitor Ultrasensitive Test, the new Cobas AmpliPrep/Cobas Amplicor HIV-1 Monitor Ultrasensitive Test and the Versant HIV RNA 3.0 assays for quantitation of HIV-1 RNA in plasma samples
    Annemarie Berger
    Institute for Medical Virology, J W Goethe University Hospital, Paul Ehrlich Street 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 33:43-51. 2005
  6. ncbi request reprint Evaluation of the Cobas AmpliPrep/Cobas Amplicor HIV-1 Monitor Ultrasensitive Test: comparison with the Cobas Amplicor HIV-1 Monitor test (manual specimen preparation)
    Annemarie Berger
    Institute for Medical Virology, J W Goethe University Hospital, Paul Ehrlich Street 40, D 60596 Frankfurt Main, Germany
    J Clin Virol 25:S103-7. 2002
  7. doi request reprint Detection and quantitation of HBV DNA in miniaturized samples: multi centre study to evaluate the performance of the COBAS ® AmpliPrep/COBAS ® TaqMan ® hepatitis B virus (HBV) test v2.0 by the use of plasma or serum specimens
    Annemarie Berger
    Institut fur Medizinische Virologie, der J W Goethe Universität Frankfurt am Main, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Virol Methods 169:404-8. 2010
  8. doi request reprint Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV): lessons from two accidental cases
    Annemarie Berger
    Institut fur Medizinische Virologie, Klinikum der J W Goethe Universitat, Paul Ehrlich Str 40, D 60596, Frankfurt am Main, Germany
    J Clin Virol 51:285-8. 2011
  9. doi request reprint Evaluation of the new ARCHITECT anti-HCV screening test under routine laboratory conditions
    Annemarie Berger
    Institute for Medical Virology, Frankfurt University Medical School, Paul Ehrlich Street 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 43:158-61. 2008
  10. ncbi request reprint The role of viral load determination for the management of human immunodeficiency virus, hepatitis B virus and hepatitis C virus infection
    A Berger
    Institut fur Medizinische Virologie, Zentrum der Hygiene, Universitatskliniken, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 20:23-30. 2001

Collaborators

Detail Information

Publications39

  1. doi request reprint Case report: risk of virus infection after accidental blood inoculation from a multi-infected AIDS patient
    Annemarie Berger
    Institute of Medical Virology, Hospital of Johann Wolfgang Goethe University, Frankfurt M, Germany
    J Med Virol 84:897-900. 2012
    ..Considering that many HIV carriers are coinfected with hepatitis B and C viruses, this case report support the knowledge that the risk of HCV transmission from a patient with AIDS is greater than that of HIV...
  2. ncbi request reprint [Antiviral treatment of chronic hepatitis C]
    Annemarie Berger
    Institut fur Medizinische Virologie, Klinikum der Johann Wolfgang Goethe Universitat, Paul Ehrlich Str 40, 60596 Frankfurt am Main
    Med Monatsschr Pharm 35:55-60. 2012
    ..In order to reduce the risk of antiviral resistance these drugs are given in combination with pegylated interferon and ribavirin only...
  3. ncbi request reprint Measurements of HCV neutralizing antibodies and of HCV-specific CD4+ and CD8+ cells using hepatitis C virus pseudo-particles (HCVpp)
    Annemarie Berger
    Institut fur Medizinische Virologie, Klinikum der J W Goethe Universitat, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 46:55-60. 2009
    ..For the medical management, it would be of great relevance to get a diagnostic marker predicting the outcome of infection...
  4. ncbi request reprint HBV reactivation after kidney transplantation
    Annemarie Berger
    Institute for Medical Virology, Center of Internal Medicine, J W Goethe University Hospital, Paul Ehrlich Str 40, D 60596 Frankfurt a M, Germany
    J Clin Virol 32:162-5. 2005
    ..Periodic follow-up of HBV serology for early diagnosis of reactivation is highly recommended in transplant recipients...
  5. ncbi request reprint Comparative evaluation of the Cobas Amplicor HIV-1 Monitor Ultrasensitive Test, the new Cobas AmpliPrep/Cobas Amplicor HIV-1 Monitor Ultrasensitive Test and the Versant HIV RNA 3.0 assays for quantitation of HIV-1 RNA in plasma samples
    Annemarie Berger
    Institute for Medical Virology, J W Goethe University Hospital, Paul Ehrlich Street 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 33:43-51. 2005
    ..There are several commercially available assays for the quantitation of HIV RNA. A new automated specimen preparation system, the Cobas AmpliPrep, was developed to automate this last part of the PCR...
  6. ncbi request reprint Evaluation of the Cobas AmpliPrep/Cobas Amplicor HIV-1 Monitor Ultrasensitive Test: comparison with the Cobas Amplicor HIV-1 Monitor test (manual specimen preparation)
    Annemarie Berger
    Institute for Medical Virology, J W Goethe University Hospital, Paul Ehrlich Street 40, D 60596 Frankfurt Main, Germany
    J Clin Virol 25:S103-7. 2002
    ..In comparison to the assay with manual extraction, no significant difference in HIV-1 RNA copy numbers was observed...
  7. doi request reprint Detection and quantitation of HBV DNA in miniaturized samples: multi centre study to evaluate the performance of the COBAS ® AmpliPrep/COBAS ® TaqMan ® hepatitis B virus (HBV) test v2.0 by the use of plasma or serum specimens
    Annemarie Berger
    Institut fur Medizinische Virologie, der J W Goethe Universität Frankfurt am Main, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Virol Methods 169:404-8. 2010
    ..99 and a mean difference of 0.06 log(10)IU/ml. In conclusion, the new test version HBV v2.0 is highly specific and reproducible and quantifies accurately HBV DNA in EDTA plasma and serum samples from patients with chronic HBV infection...
  8. doi request reprint Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV): lessons from two accidental cases
    Annemarie Berger
    Institut fur Medizinische Virologie, Klinikum der J W Goethe Universitat, Paul Ehrlich Str 40, D 60596, Frankfurt am Main, Germany
    J Clin Virol 51:285-8. 2011
    ..Passive IgG treatment of the mother was helpful but the ultimate goal in prevention of congenital CMV infection is to develop a vaccine, which would be administered to seronegative women...
  9. doi request reprint Evaluation of the new ARCHITECT anti-HCV screening test under routine laboratory conditions
    Annemarie Berger
    Institute for Medical Virology, Frankfurt University Medical School, Paul Ehrlich Street 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 43:158-61. 2008
    ..An improved test version of the Abbott ARCHITECT anti-hepatitis C virus (HCV) test became available at the end of 2005...
  10. ncbi request reprint The role of viral load determination for the management of human immunodeficiency virus, hepatitis B virus and hepatitis C virus infection
    A Berger
    Institut fur Medizinische Virologie, Zentrum der Hygiene, Universitatskliniken, Paul Ehrlich Str 40, D 60596 Frankfurt am Main, Germany
    J Clin Virol 20:23-30. 2001
    ..However, viral load may predict the outcome of antiviral therapy. Genetic diversity is another challenge for HCV RNA quantification...
  11. ncbi request reprint Severe acute respiratory syndrome (SARS)--paradigm of an emerging viral infection
    A Berger
    Institute for Medical Virology, Johann Wolfgang Goethe University Hospital, Paul Ehrlich Street 40, D 60596 Frankfurt a M, Germany
    J Clin Virol 29:13-22. 2004
    ....
  12. doi request reprint Clinical utility of the ARCHITECT HCV Ag assay for early treatment monitoring in patients with chronic hepatitis C genotype 1 infection
    Johannes Vermehren
    Medizinische Klinik 1, Klinikum der JW Goethe Universität, Frankfurt am Main, Germany
    J Clin Virol 55:17-22. 2012
    ..However, HCV-RNA assays are time-consuming, expensive and require highly trained personnel. Quantitative determination of HCV core-antigen (HCVAg) levels may be used to supplement treatment monitoring...
  13. doi request reprint Short communication: Different mutation patterns in subtype CRF06_cpx after mother-to-child transmission
    Martin Stürmer
    J W Goethe University Hospital, Institute for Medical Virology, 60596 Frankfurt, Germany
    AIDS Res Hum Retroviruses 24:1429-33. 2008
    ..Whether the nucleoside backbone, course of antiretroviral therapy, or different host environment is responsible for this variability must be determined in larger studies...
  14. ncbi request reprint Viral genome quantification as a tool for improving patient management: the example of HIV, HBV, HCV and CMV
    Annemarie Berger
    Institute for Medical Virology, Klinikum der J W Goethe Universitat, Paul Ehrlich Strasse 40, D 60596 Frankfurt am Main, Germany
    J Antimicrob Chemother 49:713-21. 2002
    ....
  15. ncbi request reprint HIV-1 genotyping: comparison of two commercially available assays
    Martin Stürmer
    Institute for Medical Virology, University Clinic Frankfurt, Paul Ehrlich Str 40, 60596 Frankfurt, Germany
    Expert Rev Mol Diagn 4:281-91. 2004
    ..A final decision on which system to use must be based on an individual's requirements. The future of this field may lie with the use of microarray systems...
  16. pmc High prevalence of anti-HCV antibodies in two metropolitan emergency departments in Germany: a prospective screening analysis of 28,809 patients
    Johannes Vermehren
    Medizinische Klinik 1, Klinikum der J W Goethe Universitat, Frankfurt am Main, Germany
    PLoS ONE 7:e41206. 2012
    ..The aim of this study was to assess the HCV seroprevalence in patients visiting two tertiary care emergency departments in Berlin and Frankfurt, respectively...
  17. ncbi request reprint Modifications and substitutions of the RNA extraction module in the ViroSeq HIV-1 genotyping system version 2: effects on sensitivity and complexity of the assay
    Martin Stürmer
    Institut fur Medizinische Virologie, J W Goethe Universitat, Frankfurt, Germany
    J Med Virol 71:475-9. 2003
    ..This is of great importance as it avoids further time- and cost-intensive steps...
  18. pmc Regional spread of HIV-1 M subtype B in middle-aged patients by random env-C2V4 region sequencing
    Martin Stürmer
    Institute for Medical Virology, University Hospital Frankfurt, Paul Ehrlich Str 40, 69596, Frankfurt, Germany
    Med Microbiol Immunol 199:123-8. 2010
    ....
  19. ncbi request reprint Molecular assays for monitoring HIV infection and antiretroviral therapy
    Miriam Wittek
    Institute for Medical Virology, JW Goethe University Hospital, Frankfurt, Germany
    Expert Rev Mol Diagn 7:237-46. 2007
    ..However, a general recommendation to favor one system over the other cannot be given, because the final decision of which system to use should be decided on the individual requirements...
  20. ncbi request reprint Verification and validation of diagnostic laboratory tests in clinical virology
    Holger F Rabenau
    Institute for Medical Virology, Johann Wolfgang Goethe University Frankfurt Main, Germany
    J Clin Virol 40:93-8. 2007
    ..It covers techniques useful for detection of virus specific antibodies, for detection of viral antigens, for detection of viral nucleic acids, and for isolation of viruses on cell cultures in the routine virology laboratory...
  21. pmc A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers
    Johannes Vermehren
    Pharmazentrum frankfurt ZAFES, Institut fur Klinische Pharmakologie, Klinikum der J W Goethe Universitat, Frankfurt am Main, Germany
    PLoS ONE 7:e32605. 2012
    ..Most significant associations were observed for the A alleles of HLA-DPA1 rs3077 and HLA-DPB1 rs9277535, which conferred a decreased risk for HBV infection. We assessed the implications of these variants for HBV infection in Caucasians...
  22. ncbi request reprint Is transmission of HIV-1 in non-viraemic serodiscordant couples possible?
    Martin Stürmer
    JW Goethe University Hospital, Institute for Medical Virology, Frankfurt, Germany
    Antivir Ther 13:729-32. 2008
    ..This should be added to the discussion of prevention strategies, which should not advise the abandonment of safer-sex practices without referring to the relatively low but not impossible risk of HIV-1 transmission in this context...
  23. ncbi request reprint Impact of tenofovir-containing antiretroviral therapy on chronic hepatitis B in a cohort co-infected with human immunodeficiency virus
    Christoph Stephan
    HIV Research and Treatment Unit at Center for Internal Medicine, Johann Wolfgang Goethe University Hospital Frankfurt, Germany
    J Antimicrob Chemother 56:1087-93. 2005
    ..We studied the impact of tenofovir disoproxil fumarate, given as an antiretroviral medication, on patients with chronic hepatitis B virus (HBV) co-infection...
  24. doi request reprint Intensification of a failing regimen with zidovudine may cause sustained virologic suppression in the presence of resensitising mutations including K65R
    C Stephan
    HIVCENTER, Johann Wolfgang Goethe University Hospital, Department of Internal Medicine II, Theodor Stern Kai 7, Frankfurt, Germany
    J Infect 61:346-50. 2010
    ..The reverse transcriptase (RT)-mutation K65R limits further therapeutic options and has been selected by unfavorable RT-combinations, e.g. tenofovir in combination with abacavir and/or didanosine...
  25. ncbi request reprint Human immunodeficiency virus and hepatitis B virus infection in pregnancy: diagnostic potential of viral genome detection
    A Berger
    Institut fur Medizinische Virologie, Zentrum der Hygiene, Universitatskliniken, Frankfurt am Main, Germany
    Intervirology 41:201-7. 1998
    ....
  26. ncbi request reprint Enterovirus infections in Germany: comparative evaluation of different laboratory diagnostic methods
    S Buxbaum
    Institute for Medical Virology, JW Goethe University Frankfurt am Main, Germany
    Infection 29:138-42. 2001
    ..Serologically, a significant rise in antibody titer may be detected and different enteroviral types can be differentiated using the neutralization assay...
  27. doi request reprint Determination of serum antibodies against swine-origin influenza A virus H1N1/09 by immunofluorescence, haemagglutination inhibition, and by neutralization tests: how is the prevalence rate of protecting antibodies in humans?
    Regina Allwinn
    Institute of Medical Virology, University Hospital, Frankfurt M, Germany
    Med Microbiol Immunol 199:117-21. 2010
    ..Expecting the next waves of influenza A/H1N1v infections, HI testing may avoid vaccinations under special risk of severe or hidden adverse reactions...
  28. ncbi request reprint Rapid detection of enterovirus infection by automated RNA extraction and real-time fluorescence PCR
    Holger F Rabenau
    Institute of Medical Virology, JWG University Frankfurt, D 60596 Frankfurt am Main, Germany
    J Clin Virol 25:155-64. 2002
    ..Molecular detection has been shown to be superior to tissue culture for the detection of enteroviruses in cerebrospinal fluid (CSF) specimens...
  29. ncbi request reprint Evaluation of the new LCx HIV RNA quantitative assay: comparison with the Cobas Amplicor HIV Monitor assay
    A Berger
    Institute for Medical Virology, Johann Wolfgang Goethe University Hospital, Frankfurt am Main, Germany
    Med Microbiol Immunol 190:129-34. 2001
    ..The results of the remaining samples showed a higher degree of variation (when testing four replicates of the subtype panel) than the LCx of 14.2-40.3%. Nevertheless, the results were comparable with the LCx data...
  30. doi request reprint Hepatitis E: are psychiatric patients on special risk?
    Claudia Reinheimer
    Institute for Medical Virology, University Hospital, Paul Ehrlich Strasse 40, 60596, Frankfurt am Main, Germany
    Med Microbiol Immunol 201:171-5. 2012
    ..0%; 95%CI: 17.86-44.61). Overall seroprevalence of anti-HEV-IgG in FFM is higher than in Germany on average. The group of AELE and PSYCH shows significantly more often marker of HEV infections than other groups in our collective...
  31. pmc Multicenter evaluation of a new automated fourth-generation human immunodeficiency virus screening assay with a sensitive antigen detection module and high specificity
    Bernard Weber
    Laboratoires Réunis Kutter Lieners Hastert, Junglinster, Luxembourg
    J Clin Microbiol 40:1938-46. 2002
    ....
  32. ncbi request reprint Evaluation of a new automated assay for hepatitis B surface antigen (HBsAg) detection VIDAS HBsAg Ultra
    Bernard Weber
    Laboratoires Réunis, Junglinster, Luxembourg, Germany
    J Virol Methods 135:109-17. 2006
    ..6% (AxSYM HBsAg v2). In conclusion, the VIDAS HBsAg Ultra is highly sensitive and specific and represents an improvement for the detection of HBsAg in routine diagnostic laboratories...
  33. pmc Evaluation of two new automated assays for hepatitis B virus surface antigen (HBsAg) detection: IMMULITE HBsAg and IMMULITE 2000 HBsAg
    Bernard Weber
    Laboratoires Réunis Kutter Lieners Hastert, Junglinster, Luxembourg
    J Clin Microbiol 41:135-43. 2003
    ..The specificity on repeatedly tested samples was equivalent to that of the alternative assays. The rapid turnaround time, primary tube sampling, and on-board dilution make it an interesting assay system for clinical laboratory diagnosis...
  34. ncbi request reprint Identification of a novel coronavirus in patients with severe acute respiratory syndrome
    Christian Drosten
    Bernhard Nocht Institute for Tropical Medicine, National Reference Center for Tropical Infectious Diseases, Hamburg, Germany
    N Engl J Med 348:1967-76. 2003
    ..The severe acute respiratory syndrome (SARS) has recently been identified as a new clinical entity. SARS is thought to be caused by an unknown infectious agent...
  35. ncbi request reprint Slower progression of HIV-1 infection in persons with GB virus C co-infection correlates with an intact T-helper 1 cytokine profile
    Giuseppe Nunnari
    University of Catania, Italy
    Ann Intern Med 139:26-30. 2003
    ..Progression to AIDS is slower in persons infected with both HIV-1 and GB virus C (GBV-C), also known as hepatitis G virus...
  36. ncbi request reprint Haemolytic anaemia after nucleotide antiretroviral treatment discontinuation in a chronic hepatitis B-virus co-infected AIDS patient
    Christoph Stephan
    AIDS 18:1613-4. 2004
  37. ncbi request reprint High-throughput purification of viral RNA based on novel aqueous chemistry for nucleic acid isolation
    Michael K Hourfar
    Institute of Transfusion Medicine and Immunohaematology, German Red Cross, Johann Wolfgang Goethe University, Frankfurt, Germany
    Clin Chem 51:1217-22. 2005
    ..However, commercially available magnetic-bead-based assays either lack the sensitivity required for viral diagnostics or are disproportionately expensive...
  38. ncbi request reprint Hepatitis A virus infection in tamarins: experimental transmission via contaminated factor VIII concentrates
    Michael Chudy
    Division of Virology, Paul Ehrlich Institut, Paul Ehrlich Strasse 51 59, 63225 Langen, Germany
    J Infect Dis 185:1170-3. 2002
    ..Because a number of HAV transmission episodes have been described for solely solvent/detergent-treated factor VIII preparations, continued use of these agents seems questionable...
  39. pmc Evaluation of a new combined antigen and antibody human immunodeficiency virus screening assay, VIDAS HIV DUO Ultra
    Bernard Weber
    Laboratoires Réunis Kutter Lieners Hastert, Junglinster, Luxembourg, Germany
    J Clin Microbiol 40:1420-6. 2002
    ..The specificity after initial and/or repeated testing of VIDAS HIV DUO Ultra was equivalent to that of a third-generation assay...